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The map label for this gene is ppx [H]

Identifier: 46447428

GI number: 46447428

Start: 2148700

End: 2149728

Strand: Direct

Name: ppx [H]

Synonym: pc1794

Alternate gene names: 46447428

Gene position: 2148700-2149728 (Clockwise)

Preceding gene: 46447424

Following gene: 46447434

Centisome position: 88.99

GC content: 37.22

Gene sequence:

>1029_bases
ATGAATCAACGTTTGGCCTGGTTATTCATGACATTATTTGTTGTATTCGCTCTATTTGCGATATCGAAACAAATGACAGA
GCCAAAAGGAGAAATACGAGCTGCTTTAGACATTGGATCTGGAGCGACTAATTTAAAAGTCGCAAGAGTCGATCCAGAAA
CAAATAAAATTATTTCTCAAATTTTTGAAAGATCTATTCCTGTTCCTTATCAAAAACATTTAGAACAGTCTAACGATAAT
ACTTTTGATCAAGTTGTTAAGCAACAAGGGATGCAAGCCATTAAAAGTTTGAAAGAAATAGCTGACGGTTATCAAGCAAA
AAAAATCATTGCTGTTGCCACTGCAGCATTTCGACAAGCGGCTAATGCTCCTCAGTTTGCACAAGAAATTGAAAAACAAA
CAGGTGTGCAAGTAAGAATCATCAATCAAGATGAAGAAGGAATCATGGCCTTTCGAGGTGCTTTAGCACTCTCTTCCGCG
GAACCTGAGAAAACTGTGGTCTGGGATATTGGAGGAGGAAGCATGCAACTAACTACACTAACAGAATCCGGAACTTATCT
TGTTGAAAAAGGCAAAACAGCCTCCATTTCATTTAAAAATGCTATTATTCAACAGATTAAACAAAAAAACATCGCCACTG
AACCTTCTCCTAATCCCATGACTTTAAAAGAAATGAACACAGCTCTCGATTATGCAGGCACTTTAGCTTTACAGACGGAT
CCTTATATTTTAGAAAAAATCCATCATCCTTCAACAAAAATGATTGCTGTCGGAAGTCTATTTAACTATGGAATTAGACC
AGTGGTTGACAACAATCAAAAAATCGAACAAGTTGAATTAGAAATGGCCGTGTATAAAATGGCAGGAAAAACCGATGCTG
ATCTTTCTGGAGGGACGTTGGCAGAAGTTGCTGTTTCCAATCCCCTCCTTGTTTTAGGTTACATGAAAGCTTTGCAAATA
TCACGATTAGAAATAATGCAAGTCAATAATGCTGATGGAGCGTTAACTTATCCTCCTTACTGGAAATAA

Upstream 100 bases:

>100_bases
TTAACATAAGAACAAAGCGAATACTTGAATTTGGCATTGATTTTGCAATCTTGAATCAGTTTATCAGTATAAACGATATC
CTTTCAGGAAAGGGGAGATT

Downstream 100 bases:

>100_bases
AATCTCTAGTTCCATTTTTTAACTTTTTGACGTTGGGTTGGTTACTCAACGTCATTTGTTTTAAACGATTTATTTTTATT
TAAATTATTCAATTAAGGTT

Product: putative exopolyphosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNQRLAWLFMTLFVVFALFAISKQMTEPKGEIRAALDIGSGATNLKVARVDPETNKIISQIFERSIPVPYQKHLEQSNDN
TFDQVVKQQGMQAIKSLKEIADGYQAKKIIAVATAAFRQAANAPQFAQEIEKQTGVQVRIINQDEEGIMAFRGALALSSA
EPEKTVVWDIGGGSMQLTTLTESGTYLVEKGKTASISFKNAIIQQIKQKNIATEPSPNPMTLKEMNTALDYAGTLALQTD
PYILEKIHHPSTKMIAVGSLFNYGIRPVVDNNQKIEQVELEMAVYKMAGKTDADLSGGTLAEVAVSNPLLVLGYMKALQI
SRLEIMQVNNADGALTYPPYWK

Sequences:

>Translated_342_residues
MNQRLAWLFMTLFVVFALFAISKQMTEPKGEIRAALDIGSGATNLKVARVDPETNKIISQIFERSIPVPYQKHLEQSNDN
TFDQVVKQQGMQAIKSLKEIADGYQAKKIIAVATAAFRQAANAPQFAQEIEKQTGVQVRIINQDEEGIMAFRGALALSSA
EPEKTVVWDIGGGSMQLTTLTESGTYLVEKGKTASISFKNAIIQQIKQKNIATEPSPNPMTLKEMNTALDYAGTLALQTD
PYILEKIHHPSTKMIAVGSLFNYGIRPVVDNNQKIEQVELEMAVYKMAGKTDADLSGGTLAEVAVSNPLLVLGYMKALQI
SRLEIMQVNNADGALTYPPYWK
>Mature_342_residues
MNQRLAWLFMTLFVVFALFAISKQMTEPKGEIRAALDIGSGATNLKVARVDPETNKIISQIFERSIPVPYQKHLEQSNDN
TFDQVVKQQGMQAIKSLKEIADGYQAKKIIAVATAAFRQAANAPQFAQEIEKQTGVQVRIINQDEEGIMAFRGALALSSA
EPEKTVVWDIGGGSMQLTTLTESGTYLVEKGKTASISFKNAIIQQIKQKNIATEPSPNPMTLKEMNTALDYAGTLALQTD
PYILEKIHHPSTKMIAVGSLFNYGIRPVVDNNQKIEQVELEMAVYKMAGKTDADLSGGTLAEVAVSNPLLVLGYMKALQI
SRLEIMQVNNADGALTYPPYWK

Specific function: Degradation Of Inorganic Polyphosphates. Orthophosphate Is Released Progressively From The Ends Of Polyphosphate Of Circa 500 Residues Long, While Chains Of Circa 15 Residues Compete Poorly With Polyphosphate As Substrate. [C]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=175, Percent_Identity=29.1428571428571, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 37629; Mature: 37629

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRLAWLFMTLFVVFALFAISKQMTEPKGEIRAALDIGSGATNLKVARVDPETNKIISQ
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEECCHHHHHHHH
IFERSIPVPYQKHLEQSNDNTFDQVVKQQGMQAIKSLKEIADGYQAKKIIAVATAAFRQA
HHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ANAPQFAQEIEKQTGVQVRIINQDEEGIMAFRGALALSSAEPEKTVVWDIGGGSMQLTTL
CCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEE
TESGTYLVEKGKTASISFKNAIIQQIKQKNIATEPSPNPMTLKEMNTALDYAGTLALQTD
ECCCCEEEECCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEEECCC
PYILEKIHHPSTKMIAVGSLFNYGIRPVVDNNQKIEQVELEMAVYKMAGKTDADLSGGTL
CHHHHHHCCCCCCEEEEHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCE
AEVAVSNPLLVLGYMKALQISRLEIMQVNNADGALTYPPYWK
EEHHHCCCCHHHHHHHHHHHHHEEEEEECCCCCEECCCCCCC
>Mature Secondary Structure
MNQRLAWLFMTLFVVFALFAISKQMTEPKGEIRAALDIGSGATNLKVARVDPETNKIISQ
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEECCHHHHHHHH
IFERSIPVPYQKHLEQSNDNTFDQVVKQQGMQAIKSLKEIADGYQAKKIIAVATAAFRQA
HHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ANAPQFAQEIEKQTGVQVRIINQDEEGIMAFRGALALSSAEPEKTVVWDIGGGSMQLTTL
CCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEE
TESGTYLVEKGKTASISFKNAIIQQIKQKNIATEPSPNPMTLKEMNTALDYAGTLALQTD
ECCCCEEEECCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEEECCC
PYILEKIHHPSTKMIAVGSLFNYGIRPVVDNNQKIEQVELEMAVYKMAGKTDADLSGGTL
CHHHHHHCCCCCCEEEEHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCE
AEVAVSNPLLVLGYMKALQISRLEIMQVNNADGALTYPPYWK
EEHHHCCCCHHHHHHHHHHHHHEEEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]