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The map label for this gene is galE [H]

Identifier: 46446936

GI number: 46446936

Start: 1557808

End: 1558776

Strand: Direct

Name: galE [H]

Synonym: pc1302

Alternate gene names: 46446936

Gene position: 1557808-1558776 (Clockwise)

Preceding gene: 46446934

Following gene: 46446938

Centisome position: 64.52

GC content: 37.56

Gene sequence:

>969_bases
ATGTCTCAACTAACAATTCTTATTGTCGGAGGAGCCGGATATATTGGTTCTCATGTCAACAAAATGCTAAATCTCATGGG
TTATCACACTATAGTTGTCGATAATCTCAGTCGAGGATCTATAAAAACTGTTCTTCATGGGACATTTGTGCAGGGAGATC
TCTGCGATCCACTTTTTCTCAATCAGCTATTCCAAAAATACTCTATTGATGCTGTCATGCATTTTGCTGCATATATCGAT
GTTGGAGAGTCTGTCGTGAATCCAGCCAAATATTATCAGAACAATGTTGTGAACACATTGAATCTTTTAACAGCAATGGT
AAAATCTCAAGTTAAAACGTTTATTTTCTCCTCAACTGCAGCCATTTTTGGCTATCCTCTTTCCAATAAGATCGGTGAAT
CTCATCCCTGTCATCCTATTAATCCCTATGGGGAAACTAAATGGGTCGTAGAAAAGATGTTACGAGATTTTGAACAGGCT
TATGGTCTTAAATATTCTTGTCTTCGCTATTTTAATGCAGCTGGAGGAGATCCTGAAGGCAAAATTAAAAATTATCAGAC
AAAATCTTCAAATCTCATCCCTCTCATCCTCAAAAGCCTTCAACATGAAACAGAATCTATCACCATTTATGGAACTGATT
ATGCAACTCCTGATGGAACATGCATCAGAGATTATATTCACATTCAAGACTTAGGGCATGCTCATATTAAAGCCTTAGAA
CAATTACTTAATGGCTCTTCTTCTACAAGCTATAATCTTGGAAACGGAAGTGGATTTAGCGTTAAAGAGGTCATCCAAAC
GGTGGAGAAAGTATTAAATAAAAAAGTTTCCTTCATTGAAGGAGCTCGTCGACCAGGTGATCCTCCCATATTGCTTGCAG
ATACACAAAAAGCAGCATCGCTATTAAATTGGCATCCTCAGTTTAGTTTAGCTAAAATGATTGATCATGCCTGGACTGCT
TATCACTAG

Upstream 100 bases:

>100_bases
CACATGAAATAGGTGGAATTGGAATAGGAGTGAGAACATAGACAAAAAAATGAATCTAACTTAGATTGATTGTTTTAAAT
TTTCAGTAATTAGTGATTGT

Downstream 100 bases:

>100_bases
AAAAGGTTTCTAATAAATACCTCTCTAAGCAGCAGTTCAAAATTCTCTCATCTAAATAAAAAAATAAAATTGATCTACAA
TTTGACAATACAATTTTTAA

Product: putative UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSQLTILIVGGAGYIGSHVNKMLNLMGYHTIVVDNLSRGSIKTVLHGTFVQGDLCDPLFLNQLFQKYSIDAVMHFAAYID
VGESVVNPAKYYQNNVVNTLNLLTAMVKSQVKTFIFSSTAAIFGYPLSNKIGESHPCHPINPYGETKWVVEKMLRDFEQA
YGLKYSCLRYFNAAGGDPEGKIKNYQTKSSNLIPLILKSLQHETESITIYGTDYATPDGTCIRDYIHIQDLGHAHIKALE
QLLNGSSSTSYNLGNGSGFSVKEVIQTVEKVLNKKVSFIEGARRPGDPPILLADTQKAASLLNWHPQFSLAKMIDHAWTA
YH

Sequences:

>Translated_322_residues
MSQLTILIVGGAGYIGSHVNKMLNLMGYHTIVVDNLSRGSIKTVLHGTFVQGDLCDPLFLNQLFQKYSIDAVMHFAAYID
VGESVVNPAKYYQNNVVNTLNLLTAMVKSQVKTFIFSSTAAIFGYPLSNKIGESHPCHPINPYGETKWVVEKMLRDFEQA
YGLKYSCLRYFNAAGGDPEGKIKNYQTKSSNLIPLILKSLQHETESITIYGTDYATPDGTCIRDYIHIQDLGHAHIKALE
QLLNGSSSTSYNLGNGSGFSVKEVIQTVEKVLNKKVSFIEGARRPGDPPILLADTQKAASLLNWHPQFSLAKMIDHAWTA
YH
>Mature_321_residues
SQLTILIVGGAGYIGSHVNKMLNLMGYHTIVVDNLSRGSIKTVLHGTFVQGDLCDPLFLNQLFQKYSIDAVMHFAAYIDV
GESVVNPAKYYQNNVVNTLNLLTAMVKSQVKTFIFSSTAAIFGYPLSNKIGESHPCHPINPYGETKWVVEKMLRDFEQAY
GLKYSCLRYFNAAGGDPEGKIKNYQTKSSNLIPLILKSLQHETESITIYGTDYATPDGTCIRDYIHIQDLGHAHIKALEQ
LLNGSSSTSYNLGNGSGFSVKEVIQTVEKVLNKKVSFIEGARRPGDPPILLADTQKAASLLNWHPQFSLAKMIDHAWTAY
H

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=330, Percent_Identity=38.4848484848485, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI56118217, Length=330, Percent_Identity=38.4848484848485, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI189083684, Length=330, Percent_Identity=38.4848484848485, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI42516563, Length=325, Percent_Identity=27.6923076923077, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI7657641, Length=278, Percent_Identity=29.8561151079137, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI1786974, Length=326, Percent_Identity=39.5705521472393, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1788353, Length=350, Percent_Identity=27.7142857142857, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994969, Length=339, Percent_Identity=28.6135693215339, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788365, Length=328, Percent_Identity=24.6951219512195, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71982038, Length=336, Percent_Identity=35.1190476190476, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI71982035, Length=334, Percent_Identity=35.6287425149701, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17539532, Length=327, Percent_Identity=26.605504587156, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17568069, Length=303, Percent_Identity=27.3927392739274, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=332, Percent_Identity=36.7469879518072, Blast_Score=199, Evalue=7e-52,
Organism=Drosophila melanogaster, GI19923002, Length=338, Percent_Identity=38.1656804733728, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI21356223, Length=316, Percent_Identity=26.8987341772152, Blast_Score=104, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35680; Mature: 35549

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLTILIVGGAGYIGSHVNKMLNLMGYHTIVVDNLSRGSIKTVLHGTFVQGDLCDPLFL
CCCEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHCCCCCCCCCCHHHH
NQLFQKYSIDAVMHFAAYIDVGESVVNPAKYYQNNVVNTLNLLTAMVKSQVKTFIFSSTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AIFGYPLSNKIGESHPCHPINPYGETKWVVEKMLRDFEQAYGLKYSCLRYFNAAGGDPEG
HHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCC
KIKNYQTKSSNLIPLILKSLQHETESITIYGTDYATPDGTCIRDYIHIQDLGHAHIKALE
CCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHH
QLLNGSSSTSYNLGNGSGFSVKEVIQTVEKVLNKKVSFIEGARRPGDPPILLADTQKAAS
HHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHH
LLNWHPQFSLAKMIDHAWTAYH
HHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQLTILIVGGAGYIGSHVNKMLNLMGYHTIVVDNLSRGSIKTVLHGTFVQGDLCDPLFL
CCEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHCCCCCCCCCCHHHH
NQLFQKYSIDAVMHFAAYIDVGESVVNPAKYYQNNVVNTLNLLTAMVKSQVKTFIFSSTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AIFGYPLSNKIGESHPCHPINPYGETKWVVEKMLRDFEQAYGLKYSCLRYFNAAGGDPEG
HHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCC
KIKNYQTKSSNLIPLILKSLQHETESITIYGTDYATPDGTCIRDYIHIQDLGHAHIKALE
CCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHH
QLLNGSSSTSYNLGNGSGFSVKEVIQTVEKVLNKKVSFIEGARRPGDPPILLADTQKAAS
HHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHH
LLNWHPQFSLAKMIDHAWTAYH
HHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]