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The map label for this gene is rpiA

Identifier: 46446809

GI number: 46446809

Start: 1402002

End: 1402700

Strand: Direct

Name: rpiA

Synonym: pc1175

Alternate gene names: 46446809

Gene position: 1402002-1402700 (Clockwise)

Preceding gene: 46446808

Following gene: 46446810

Centisome position: 58.07

GC content: 36.77

Gene sequence:

>699_bases
ATGACACAAACAAACGATTCGCCATCCATTAAAGCAAAAAAGGCAGCTGCCCTTAAAGCTGTAGAATTTGTTCAAGATCA
AATGATTATTGGTTTAGGAACAGGTTCCACAATAGCCTACTTCATTGAAGCTTTGGGTAAGCGCTGTCAAGCAGGCCTAA
AAATAACTGCAATTGCCTCTTCAGAACGATCCATGCGGCAGGCTCGATTGGTTGGCATTCCTATTGTCGATTCAGACACT
ATTTTAGAATTAGATTTAACAATCGATGGAGCGGACGAAATAGATCCTCTCAAACAGATGATTAAAGGAGGAGGAGGAGC
TCTTTTACGAGAAAAACTCATTGCCTCAGCAAGTAAAGAAATGATCGTTGTTATCGATGAGACTAAACTTGTGAATAAAT
TAGGAAAATTTCCCGTAGCTACCGAGATTTCAATATTTACATTTCGTCATATAGTAAAAAAACTTAAGGATCACGGTTAT
TGCGGATCGTTACGAGTTAATCAAGATCAGAGTTTGTATCGTACAGATAATGGAAATTATATTTTTGATATTTGTTTTCC
TGAACCTATTGACAATCCTATTTTTGAACATAATCGGCTTAAAAGTTTTGCCGGGGTTTTAGAAACTGGCCTTTTTTTTA
ATTTAGCAGGGCGTGTTATCATTGGATACCAAAATGGAATGACTAAAATTGTTGCATGA

Upstream 100 bases:

>100_bases
ATTTATCCTGCTTTAAATACAGAGATGCAAGCCTATTGGTTGTCCCTTTGGGGCATAAATTTCTCTGATTAATAAGCTTA
TTTTTGACAAGGAATTTTAT

Downstream 100 bases:

>100_bases
CTTATAAAAAAAATGCTTATTTATTAAAATAATAGATTTTTTCTTCAAAGAATTAGGATAGTATAAAGAAATCTCATTAA
ATATGATTAATTAGACTAAT

Product: putative ribose 5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTQTNDSPSIKAKKAAALKAVEFVQDQMIIGLGTGSTIAYFIEALGKRCQAGLKITAIASSERSMRQARLVGIPIVDSDT
ILELDLTIDGADEIDPLKQMIKGGGGALLREKLIASASKEMIVVIDETKLVNKLGKFPVATEISIFTFRHIVKKLKDHGY
CGSLRVNQDQSLYRTDNGNYIFDICFPEPIDNPIFEHNRLKSFAGVLETGLFFNLAGRVIIGYQNGMTKIVA

Sequences:

>Translated_232_residues
MTQTNDSPSIKAKKAAALKAVEFVQDQMIIGLGTGSTIAYFIEALGKRCQAGLKITAIASSERSMRQARLVGIPIVDSDT
ILELDLTIDGADEIDPLKQMIKGGGGALLREKLIASASKEMIVVIDETKLVNKLGKFPVATEISIFTFRHIVKKLKDHGY
CGSLRVNQDQSLYRTDNGNYIFDICFPEPIDNPIFEHNRLKSFAGVLETGLFFNLAGRVIIGYQNGMTKIVA
>Mature_231_residues
TQTNDSPSIKAKKAAALKAVEFVQDQMIIGLGTGSTIAYFIEALGKRCQAGLKITAIASSERSMRQARLVGIPIVDSDTI
LELDLTIDGADEIDPLKQMIKGGGGALLREKLIASASKEMIVVIDETKLVNKLGKFPVATEISIFTFRHIVKKLKDHGYC
GSLRVNQDQSLYRTDNGNYIFDICFPEPIDNPIFEHNRLKSFAGVLETGLFFNLAGRVIIGYQNGMTKIVA

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=224, Percent_Identity=33.4821428571429, Blast_Score=105, Evalue=3e-23,
Organism=Escherichia coli, GI1789280, Length=220, Percent_Identity=39.5454545454545, Blast_Score=133, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17551758, Length=232, Percent_Identity=33.6206896551724, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6324669, Length=250, Percent_Identity=32.8, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281364072, Length=215, Percent_Identity=34.4186046511628, Blast_Score=104, Evalue=4e-23,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_PARUW (Q6MC00)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008174.1
- ProteinModelPortal:   Q6MC00
- SMR:   Q6MC00
- STRING:   Q6MC00
- GeneID:   2780519
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1175
- NMPDR:   fig|264201.1.peg.1175
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   HAREKIV
- PhylomeDB:   Q6MC00
- ProtClustDB:   CLSK2762341
- BioCyc:   CPRO264201:PC1175-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 25396; Mature: 25265

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTNDSPSIKAKKAAALKAVEFVQDQMIIGLGTGSTIAYFIEALGKRCQAGLKITAIAS
CCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEC
SERSMRQARLVGIPIVDSDTILELDLTIDGADEIDPLKQMIKGGGGALLREKLIASASKE
CHHHHHHHHEEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCC
MIVVIDETKLVNKLGKFPVATEISIFTFRHIVKKLKDHGYCGSLRVNQDQSLYRTDNGNY
EEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEECCCCE
IFDICFPEPIDNPIFEHNRLKSFAGVLETGLFFNLAGRVIIGYQNGMTKIVA
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCEEEEEECCCCEEECC
>Mature Secondary Structure 
TQTNDSPSIKAKKAAALKAVEFVQDQMIIGLGTGSTIAYFIEALGKRCQAGLKITAIAS
CCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEC
SERSMRQARLVGIPIVDSDTILELDLTIDGADEIDPLKQMIKGGGGALLREKLIASASKE
CHHHHHHHHEEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCC
MIVVIDETKLVNKLGKFPVATEISIFTFRHIVKKLKDHGYCGSLRVNQDQSLYRTDNGNY
EEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEECCCCE
IFDICFPEPIDNPIFEHNRLKSFAGVLETGLFFNLAGRVIIGYQNGMTKIVA
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCEEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA