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The map label for this gene is dnaQ [H]

Identifier: 46446795

GI number: 46446795

Start: 1388733

End: 1389383

Strand: Direct

Name: dnaQ [H]

Synonym: pc1161

Alternate gene names: 46446795

Gene position: 1388733-1389383 (Clockwise)

Preceding gene: 46446794

Following gene: 46446796

Centisome position: 57.52

GC content: 38.71

Gene sequence:

>651_bases
GTGATTGAAATTGCTGCCTATGACCCTGTTCAAAATCGACGGTTTGAGAAATTCGTTCATCCTGGTTTTCCGATTCCTCC
AGAATCCACCGCTATTCATCATATCACTGATGAAATGGTTGCAAACGCAGGTTCTTTTGCAGATGTCGGGGCAGAATTTG
TCGAATTTTGTGCCGGTGAAGTTGTTTTAATCGCGCATAATAATGACAATTTTGACCTTCATTTTCTACGGCACGAATTT
GAGAGGAATCAACTTATTCTTCCAACTCATTGGAAGTTTCTTGATTCTTTAAAATGGGCACGACGGTACCGATCAGATCT
CCCTCGGCATACATTACAGTTTTTAAGAGAAATTTATGGAATAACTGCTAACAATGCGCACAGGGCATTAGATGACGTGA
TTGTTTTAGAAAGAGTTTTTCGCTCAATGGTTGATGATTTAGAAATTCAAGATGTATTTGATTTATTAAATCGCCCAAGA
GCTATCCAACATATGCCTTTTGGCAAACACCAAGGGCAGCCCTTAAATAAAATTCCAAAAAATTATATCTCATGGCTAGC
AACGACAGGGGCTTTTGATAAACCTGAAAATCAAGAACTGAAAGCAAGTTTTGTAAAGCTTGGCTTACTAGAAATGGCAG
AATCCATGTGA

Upstream 100 bases:

>100_bases
GGAAAAAACACGTGAAATGGAGAATGAAAGCTAATCCATGTCTTTAAGAGCGATTTACTATGATACAGAAACGACAGGCA
TAAAACCCGAAAAAGATCGG

Downstream 100 bases:

>100_bases
GAATCGGAATTTTAGGATGTGGATATGTTGGTCAAGCTGCCGCAGTTTTCTGGAAAAATCAATCTCATTTTTTAACTGTT
ACCACACGGCAGATAGAAAA

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MIEIAAYDPVQNRRFEKFVHPGFPIPPESTAIHHITDEMVANAGSFADVGAEFVEFCAGEVVLIAHNNDNFDLHFLRHEF
ERNQLILPTHWKFLDSLKWARRYRSDLPRHTLQFLREIYGITANNAHRALDDVIVLERVFRSMVDDLEIQDVFDLLNRPR
AIQHMPFGKHQGQPLNKIPKNYISWLATTGAFDKPENQELKASFVKLGLLEMAESM

Sequences:

>Translated_216_residues
MIEIAAYDPVQNRRFEKFVHPGFPIPPESTAIHHITDEMVANAGSFADVGAEFVEFCAGEVVLIAHNNDNFDLHFLRHEF
ERNQLILPTHWKFLDSLKWARRYRSDLPRHTLQFLREIYGITANNAHRALDDVIVLERVFRSMVDDLEIQDVFDLLNRPR
AIQHMPFGKHQGQPLNKIPKNYISWLATTGAFDKPENQELKASFVKLGLLEMAESM
>Mature_216_residues
MIEIAAYDPVQNRRFEKFVHPGFPIPPESTAIHHITDEMVANAGSFADVGAEFVEFCAGEVVLIAHNNDNFDLHFLRHEF
ERNQLILPTHWKFLDSLKWARRYRSDLPRHTLQFLREIYGITANNAHRALDDVIVLERVFRSMVDDLEIQDVFDLLNRPR
AIQHMPFGKHQGQPLNKIPKNYISWLATTGAFDKPENQELKASFVKLGLLEMAESM

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25007; Mature: 25007

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEIAAYDPVQNRRFEKFVHPGFPIPPESTAIHHITDEMVANAGSFADVGAEFVEFCAGE
CEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
VVLIAHNNDNFDLHFLRHEFERNQLILPTHWKFLDSLKWARRYRSDLPRHTLQFLREIYG
EEEEEECCCCCCHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
ITANNAHRALDDVIVLERVFRSMVDDLEIQDVFDLLNRPRAIQHMPFGKHQGQPLNKIPK
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHH
NYISWLATTGAFDKPENQELKASFVKLGLLEMAESM
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIEIAAYDPVQNRRFEKFVHPGFPIPPESTAIHHITDEMVANAGSFADVGAEFVEFCAGE
CEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
VVLIAHNNDNFDLHFLRHEFERNQLILPTHWKFLDSLKWARRYRSDLPRHTLQFLREIYG
EEEEEECCCCCCHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
ITANNAHRALDDVIVLERVFRSMVDDLEIQDVFDLLNRPRAIQHMPFGKHQGQPLNKIPK
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHH
NYISWLATTGAFDKPENQELKASFVKLGLLEMAESM
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]