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The map label for this gene is ruvB

Identifier: 46446742

GI number: 46446742

Start: 1328687

End: 1329685

Strand: Reverse

Name: ruvB

Synonym: pc1108

Alternate gene names: 46446742

Gene position: 1329685-1328687 (Counterclockwise)

Preceding gene: 46446747

Following gene: 46446741

Centisome position: 55.07

GC content: 38.64

Gene sequence:

>999_bases
ATGAATAAAAATTTTATTGAATCTAACCTAAATAAGCAAGAGCTCTCTTTTGAAGTTCCTTTACGCCCTCAGTGTTTAAC
TGACTTTGTCGGTCAAGATTCAATTCGTGATCGATTAGAGGTTCATATTGGAGCCGCTAGGCAACGAGGAGAGGTTCTAG
GGCATTGTTTATTTAGCGGTCCTCCTGGGCTTGGTAAAACGACTCTTGCTTCTATTCTTTCTAAAGCAATGGAATCAAAT
TTAGTTTTAACTTCTGGGCCTGTTATTGAGAAGGCAGGAGATTTAGCCGGTATTCTAACCAGTCTAAAAACTGGGGATGT
ATTATTTATTGATGAAATCCATCGTTTAAATCGGTCCGTTGAAGAATATTTATATCAGGCAATGGAAGATTTTGCGTTAG
ATTTAATGATTGATAGTGGTCCCAATGCACGCAGTATTCAGGTAAAACTTAACCAATTTACCTTAGCAGGCGCTACAACT
CGTTTAGGATTGCTTTCAGAACCTCTTCGTTCCCGATTTGCTTTTACATGTCGTCTTGAATATTATGATCCCATGATTTT
ACAAAAAATTTTGTTGAGAACAAGCCGAATTTTAAATGTCAAAATTGATTCGGAAGCTGCTTTGGAAATTGCCAAAAGAT
CTCGAGGAACTCCTCGGGTGGCTAATCATCTGCTTCGCTGGGTTCGTGATTTTGCTCAAATAAAAGCTAACAACTACATT
GATCTTTCTGTTGCCAATCGAGCTTTGACCATGCTTTCCATTGATGAAAAGGGACTGGATGAAATGGATAAAAAAATGTT
ACAGACAATGATCGATCATTACAGTGGAGGGCCTGTAGGAATTAACGCTATCGCCGCATCAATTGGGGAAGAGCCTTCAA
CTGTTGAAGAAGTTTATGAACCTTATTTAATTTTGCAAGGGTTGTTAAAACGAACTCCCAGAGGACGAGAAGTGACTTCC
TTAGGCTATCAACATATCGTAGGATCTTCACAAAGATAA

Upstream 100 bases:

>100_bases
TGTATCTTATTCTCATCCAGATCAAATTCAATTCTTATTTGAAAGCTTTGCATAGGCAATCAGAATTGAAAAGTTTTAAA
GCTTGAAGGCAACTCCATTC

Downstream 100 bases:

>100_bases
AATAAATGACAAATAAATAGGAGAAAGAAGATGGTATTAATGAGATTTCTTCTGCTTGCTTTAACGGTTTTACCGTTAAC
TGTTCAGTTACAAGCGGGAA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNKNFIESNLNKQELSFEVPLRPQCLTDFVGQDSIRDRLEVHIGAARQRGEVLGHCLFSGPPGLGKTTLASILSKAMESN
LVLTSGPVIEKAGDLAGILTSLKTGDVLFIDEIHRLNRSVEEYLYQAMEDFALDLMIDSGPNARSIQVKLNQFTLAGATT
RLGLLSEPLRSRFAFTCRLEYYDPMILQKILLRTSRILNVKIDSEAALEIAKRSRGTPRVANHLLRWVRDFAQIKANNYI
DLSVANRALTMLSIDEKGLDEMDKKMLQTMIDHYSGGPVGINAIAASIGEEPSTVEEVYEPYLILQGLLKRTPRGREVTS
LGYQHIVGSSQR

Sequences:

>Translated_332_residues
MNKNFIESNLNKQELSFEVPLRPQCLTDFVGQDSIRDRLEVHIGAARQRGEVLGHCLFSGPPGLGKTTLASILSKAMESN
LVLTSGPVIEKAGDLAGILTSLKTGDVLFIDEIHRLNRSVEEYLYQAMEDFALDLMIDSGPNARSIQVKLNQFTLAGATT
RLGLLSEPLRSRFAFTCRLEYYDPMILQKILLRTSRILNVKIDSEAALEIAKRSRGTPRVANHLLRWVRDFAQIKANNYI
DLSVANRALTMLSIDEKGLDEMDKKMLQTMIDHYSGGPVGINAIAASIGEEPSTVEEVYEPYLILQGLLKRTPRGREVTS
LGYQHIVGSSQR
>Mature_332_residues
MNKNFIESNLNKQELSFEVPLRPQCLTDFVGQDSIRDRLEVHIGAARQRGEVLGHCLFSGPPGLGKTTLASILSKAMESN
LVLTSGPVIEKAGDLAGILTSLKTGDVLFIDEIHRLNRSVEEYLYQAMEDFALDLMIDSGPNARSIQVKLNQFTLAGATT
RLGLLSEPLRSRFAFTCRLEYYDPMILQKILLRTSRILNVKIDSEAALEIAKRSRGTPRVANHLLRWVRDFAQIKANNYI
DLSVANRALTMLSIDEKGLDEMDKKMLQTMIDHYSGGPVGINAIAASIGEEPSTVEEVYEPYLILQGLLKRTPRGREVTS
LGYQHIVGSSQR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=306, Percent_Identity=54.5751633986928, Blast_Score=345, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_PARUW (Q6MC67)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008107.1
- ProteinModelPortal:   Q6MC67
- SMR:   Q6MC67
- STRING:   Q6MC67
- GeneID:   2779416
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1108
- NMPDR:   fig|264201.1.peg.1108
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   CPRO264201:PC1108-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 36960; Mature: 36960

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNFIESNLNKQELSFEVPLRPQCLTDFVGQDSIRDRLEVHIGAARQRGEVLGHCLFSG
CCCCCHHCCCCHHHCEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPGLGKTTLASILSKAMESNLVLTSGPVIEKAGDLAGILTSLKTGDVLFIDEIHRLNRSV
CCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
EEYLYQAMEDFALDLMIDSGPNARSIQVKLNQFTLAGATTRLGLLSEPLRSRFAFTCRLE
HHHHHHHHHHHEEEEEEECCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHEEEEEEEC
YYDPMILQKILLRTSRILNVKIDSEAALEIAKRSRGTPRVANHLLRWVRDFAQIKANNYI
CCCHHHHHHHHHHHHHEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEE
DLSVANRALTMLSIDEKGLDEMDKKMLQTMIDHYSGGPVGINAIAASIGEEPSTVEEVYE
EEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHH
PYLILQGLLKRTPRGREVTSLGYQHIVGSSQR
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKNFIESNLNKQELSFEVPLRPQCLTDFVGQDSIRDRLEVHIGAARQRGEVLGHCLFSG
CCCCCHHCCCCHHHCEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPGLGKTTLASILSKAMESNLVLTSGPVIEKAGDLAGILTSLKTGDVLFIDEIHRLNRSV
CCCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
EEYLYQAMEDFALDLMIDSGPNARSIQVKLNQFTLAGATTRLGLLSEPLRSRFAFTCRLE
HHHHHHHHHHHEEEEEEECCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHEEEEEEEC
YYDPMILQKILLRTSRILNVKIDSEAALEIAKRSRGTPRVANHLLRWVRDFAQIKANNYI
CCCHHHHHHHHHHHHHEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEE
DLSVANRALTMLSIDEKGLDEMDKKMLQTMIDHYSGGPVGINAIAASIGEEPSTVEEVYE
EEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHH
PYLILQGLLKRTPRGREVTSLGYQHIVGSSQR
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA