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The map label for this gene is ribD [H]

Identifier: 46446676

GI number: 46446676

Start: 1240454

End: 1241560

Strand: Direct

Name: ribD [H]

Synonym: pc1042

Alternate gene names: 46446676

Gene position: 1240454-1241560 (Clockwise)

Preceding gene: 46446674

Following gene: 46446680

Centisome position: 51.38

GC content: 38.66

Gene sequence:

>1107_bases
ATGAAAAACTCTGAAATACATCATACGTTCATGCTAGAAGCCATTGCAGAATCTTGGAAAGCACGTCTTCATGCTCCTCC
TAATCCTTGGGTGGGATGTGTCATTGTCAAAGATCAAAAAATCATTGGAAAAGGTTATACATATCCATCAGGACAAGCTC
ATGCTGAAATCAATGCCTTAAAATCAGCTAGTGAAAATGCTAAAGGAGCTTCTTTATACGTAACTTTAGAGCCCTGCTCT
CATCATGGAAAAACACCACCTTGCACAGAAGCGATTATTCGCGCAGGGATTTTAAATGTCTATGTGGCTTTAAAAGATCC
TGATTCACGAGTTCGAGGGCAAGGGATTCAGAAACTCCGAGAAGCAGGTATTCATGTTAAAGTAGGAATTGGTGAAAAAG
AAGCAAAAGTTGTATTAACCCCTTATTTATATCAACGTGAAAGCCAAATCCCTTATACAGTCTTAAAAATAGCGACAAGC
GTTGATGGTCGAACAGCTGCTGTGGATGGAACTTCTCAATGGTTAACGTCTTCTGAAGCACGATTAGATGCGCATCTGCA
AAGAGCTTATTCCCAAGCGGTTGTAATCGGATCTGGAACTGCGACTATTGACTCGCCTCAACTTACAGTTCGACATCCAA
CTATTCATCTATTTCAACAACCACAAAGAATTTTAATTGATTCTAGCGGCAAAACTCCTGCAACAGGCCTCTTATTTGAT
CAAAAGTTAGCCCCAACTCTTGTTTTAACAACGAAAGCTTCATCTATTACGAGGCAAAATGAATGGTTAAAAACTGGGGC
AGAGGTCATTGTGATTTCTGCAACAAAAAATGGGCATGTCAACTTACGCGAAGCATGGCAATTACTTGCGAAAAGAGGAA
TTATTCAAGTTCTTGTCGAGGGTGGATCTACGTTACAAAGTGCTTTGTTAGAAATCGGTCTTGTTAATTGTCTGTCAGTT
TATACAGGGCCATTATTAATAGGTAAAAGCGGACTTCCACTATTTTCTAAGGAAATTCCGACTCTAAAAAAAGCCAAGTT
GTTAAAAATTCAAAATATCAAACAGTTCGACAATTCCTTTCGAGTAGATTATTTACTAAAAGTTTAA

Upstream 100 bases:

>100_bases
TTCATATTATTTAATTGGCTCGAGCTTTGAGTTTTCTAGATTTATTGTTAACATTTGTTAATTAAGATAAGTTTATTTAA
ATTATTAGGATAATTTTTCA

Downstream 100 bases:

>100_bases
TCTAGGTAAAGGAGAAAGCTTTTTAAATAATCGCTTTCTGGATGAAACAGATTAATGGGGTGGTCACAGGCTAATTGATG
TCTACCGATGAGGCGTACAT

Product: diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKNSEIHHTFMLEAIAESWKARLHAPPNPWVGCVIVKDQKIIGKGYTYPSGQAHAEINALKSASENAKGASLYVTLEPCS
HHGKTPPCTEAIIRAGILNVYVALKDPDSRVRGQGIQKLREAGIHVKVGIGEKEAKVVLTPYLYQRESQIPYTVLKIATS
VDGRTAAVDGTSQWLTSSEARLDAHLQRAYSQAVVIGSGTATIDSPQLTVRHPTIHLFQQPQRILIDSSGKTPATGLLFD
QKLAPTLVLTTKASSITRQNEWLKTGAEVIVISATKNGHVNLREAWQLLAKRGIIQVLVEGGSTLQSALLEIGLVNCLSV
YTGPLLIGKSGLPLFSKEIPTLKKAKLLKIQNIKQFDNSFRVDYLLKV

Sequences:

>Translated_368_residues
MKNSEIHHTFMLEAIAESWKARLHAPPNPWVGCVIVKDQKIIGKGYTYPSGQAHAEINALKSASENAKGASLYVTLEPCS
HHGKTPPCTEAIIRAGILNVYVALKDPDSRVRGQGIQKLREAGIHVKVGIGEKEAKVVLTPYLYQRESQIPYTVLKIATS
VDGRTAAVDGTSQWLTSSEARLDAHLQRAYSQAVVIGSGTATIDSPQLTVRHPTIHLFQQPQRILIDSSGKTPATGLLFD
QKLAPTLVLTTKASSITRQNEWLKTGAEVIVISATKNGHVNLREAWQLLAKRGIIQVLVEGGSTLQSALLEIGLVNCLSV
YTGPLLIGKSGLPLFSKEIPTLKKAKLLKIQNIKQFDNSFRVDYLLKV
>Mature_368_residues
MKNSEIHHTFMLEAIAESWKARLHAPPNPWVGCVIVKDQKIIGKGYTYPSGQAHAEINALKSASENAKGASLYVTLEPCS
HHGKTPPCTEAIIRAGILNVYVALKDPDSRVRGQGIQKLREAGIHVKVGIGEKEAKVVLTPYLYQRESQIPYTVLKIATS
VDGRTAAVDGTSQWLTSSEARLDAHLQRAYSQAVVIGSGTATIDSPQLTVRHPTIHLFQQPQRILIDSSGKTPATGLLFD
QKLAPTLVLTTKASSITRQNEWLKTGAEVIVISATKNGHVNLREAWQLLAKRGIIQVLVEGGSTLQSALLEIGLVNCLSV
YTGPLLIGKSGLPLFSKEIPTLKKAKLLKIQNIKQFDNSFRVDYLLKV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=360, Percent_Identity=40.5555555555556, Blast_Score=237, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40128; Mature: 40128

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSEIHHTFMLEAIAESWKARLHAPPNPWVGCVIVKDQKIIGKGYTYPSGQAHAEINAL
CCCCCHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEECCEEEECCCCCCCCCCHHHHHHH
KSASENAKGASLYVTLEPCSHHGKTPPCTEAIIRAGILNVYVALKDPDSRVRGQGIQKLR
HHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCEEEEEEEEECCCHHHHHHHHHHHH
EAGIHVKVGIGEKEAKVVLTPYLYQRESQIPYTVLKIATSVDGRTAAVDGTSQWLTSSEA
HCCCEEEEECCCCCCEEEECCHHHCCCCCCCEEEEEEECCCCCCEEEECCCHHHHCCCHH
RLDAHLQRAYSQAVVIGSGTATIDSPQLTVRHPTIHLFQQPQRILIDSSGKTPATGLLFD
HHHHHHHHHHHCEEEEECCCEEECCCEEEEECCEEEEECCCCEEEEECCCCCCCCCEEEC
QKLAPTLVLTTKASSITRQNEWLKTGAEVIVISATKNGHVNLREAWQLLAKRGIIQVLVE
CCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHHHCCCEEEEEC
GGSTLQSALLEIGLVNCLSVYTGPLLIGKSGLPLFSKEIPTLKKAKLLKIQNIKQFDNSF
CCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCC
RVDYLLKV
CEEEEEEC
>Mature Secondary Structure
MKNSEIHHTFMLEAIAESWKARLHAPPNPWVGCVIVKDQKIIGKGYTYPSGQAHAEINAL
CCCCCHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEECCEEEECCCCCCCCCCHHHHHHH
KSASENAKGASLYVTLEPCSHHGKTPPCTEAIIRAGILNVYVALKDPDSRVRGQGIQKLR
HHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCEEEEEEEEECCCHHHHHHHHHHHH
EAGIHVKVGIGEKEAKVVLTPYLYQRESQIPYTVLKIATSVDGRTAAVDGTSQWLTSSEA
HCCCEEEEECCCCCCEEEECCHHHCCCCCCCEEEEEEECCCCCCEEEECCCHHHHCCCHH
RLDAHLQRAYSQAVVIGSGTATIDSPQLTVRHPTIHLFQQPQRILIDSSGKTPATGLLFD
HHHHHHHHHHHCEEEEECCCEEECCCEEEEECCEEEEECCCCEEEEECCCCCCCCCEEEC
QKLAPTLVLTTKASSITRQNEWLKTGAEVIVISATKNGHVNLREAWQLLAKRGIIQVLVE
CCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHHHCCCEEEEEC
GGSTLQSALLEIGLVNCLSVYTGPLLIGKSGLPLFSKEIPTLKKAKLLKIQNIKQFDNSF
CCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCC
RVDYLLKV
CEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]