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The map label for this gene is norM [H]

Identifier: 46446615

GI number: 46446615

Start: 1178115

End: 1179518

Strand: Reverse

Name: norM [H]

Synonym: pc0981

Alternate gene names: 46446615

Gene position: 1179518-1178115 (Counterclockwise)

Preceding gene: 46446618

Following gene: 46446613

Centisome position: 48.85

GC content: 37.46

Gene sequence:

>1404_bases
TTGATGATAGGTGATTATATGATGTCTTCTCCTTTGTCTCCTTTGAATTTGAATAAATTAACAGCTTATCCTCAAGGTTC
GATGGGGGAGTTGTGGCAAATTTCTTTTCCTTTAATGCTTTCTCTGATGTCTGTCAGTTTAATGCTTTTTCTAGACCGCC
TATTTTTAGCTAACTATTCTCTTGAGGCTCTAAATGCTTCTGCTAATGCAGGAATTCTAGTTCAGTTTTTGCAGTTTTGG
TGTATTTCAACTGTTAGTGTCGCTGAAATTTTTGTAGGGCGTTATAATGGATCAAAAAAATTTGAAAAGTTAGGTCAACC
TGTTTGGCAAATGATTTGGCTTTCTTTAGCCTCTTTTTTTTGGTTTATTCCTCTTGCTTTATGGGCTGGCCCTTATTTTT
TTGATGGTCATCCTTCTGCTTTGCTAGAAATAGAGTATTTCAAATATTTGTTGTGTTTTGGTCCTCTGGCAGCTCTTTCA
GGAGCGATTTCTGCTTTTTACATTGGACAAGGACAGGTAAAGTGTGTGACTTGCGTAATGGCTGTTTCGAATCTGGTGAA
TATCGGCTTAGATTATTTGTTAATTTTCGGGTGGGAGCCGTGGATTCCTGCTTTAGGTATTAAAGGAGCTGCTATCGCAA
CTGGAATAGCTCTGACAGTTCAAGTTGTAATTTTCGGGTGGGATTTTTTCAAAGCCAGTAATCGAAAAGAAAAAGGGACT
AACAAATGGCGAATTAATAAACGTCTTTTTCGGAAAAGCCTTAGTATTGGCATCCCCAATGCTTTTGCTCACACACTCGA
ATTGATGGCTTGGGTTTTGATTTTTCATTTGATGACAAAACTAGGAACAGATTACATCACAGTTGTGACAGTCGCGCAAA
GTATTTTCTTTCTTTTCACTTTTATGACGGAGGGTGTTTCTAAAGGAGCAACAGCGATTGCTGCAAATTTTTTTGGAGCA
GAGCAACATGAACTTGTGTGGAAATTACTAAAATCAGGTTTAAAGCTTTACTTATTCGTTTTTTTACTTTTAGGCGTCAT
TTTAGTTTGGTATCCAGATCCCTTAATCCATTTATTTTTAGTACAAAAAGAAGCTCTAAGTCCTGCCGTACTTTCTACTT
TACATGCAGCATGTTTTTGGGTTTGGTTATTTTTTCTATTTGATGGAATTAATTGGTTGTTAGTCGGGCTATTAACGGCT
GCAGGGGATACGCGTTTTATTATGAAAGTGGGAGGTACAGGTCCTTGGATTGTGGCTTTGTTACCCATTTACTTCTTCGT
ATTTAAGTGGGGAGCTCCGGCAAATATTGCTTGGATGTTAATTGCTCTGTATGGAGTTGTTTCTAGCCTCATTTACTTAT
GGCGTTTCAAAACCGAAAAATGGAAATATGCTTTTGTGACTTAA

Upstream 100 bases:

>100_bases
TTTTTATCAGATCAGCAAAAAAATTGTGTGAAAAAATGTAAATTAAATCACTGATCAGTCGAAAAAAATCGTGAGACCAA
AAGAAATTACTTTTGGACTA

Downstream 100 bases:

>100_bases
GCCGATGCTGAATGACGACACTGGAAGCTGCCATTCAGAATTGATTTATCTTTTTGGTTATAAAGAATTTTCTCGGCAGC
AAAATGCTTTTAAATTTGTC

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MMIGDYMMSSPLSPLNLNKLTAYPQGSMGELWQISFPLMLSLMSVSLMLFLDRLFLANYSLEALNASANAGILVQFLQFW
CISTVSVAEIFVGRYNGSKKFEKLGQPVWQMIWLSLASFFWFIPLALWAGPYFFDGHPSALLEIEYFKYLLCFGPLAALS
GAISAFYIGQGQVKCVTCVMAVSNLVNIGLDYLLIFGWEPWIPALGIKGAAIATGIALTVQVVIFGWDFFKASNRKEKGT
NKWRINKRLFRKSLSIGIPNAFAHTLELMAWVLIFHLMTKLGTDYITVVTVAQSIFFLFTFMTEGVSKGATAIAANFFGA
EQHELVWKLLKSGLKLYLFVFLLLGVILVWYPDPLIHLFLVQKEALSPAVLSTLHAACFWVWLFFLFDGINWLLVGLLTA
AGDTRFIMKVGGTGPWIVALLPIYFFVFKWGAPANIAWMLIALYGVVSSLIYLWRFKTEKWKYAFVT

Sequences:

>Translated_467_residues
MMIGDYMMSSPLSPLNLNKLTAYPQGSMGELWQISFPLMLSLMSVSLMLFLDRLFLANYSLEALNASANAGILVQFLQFW
CISTVSVAEIFVGRYNGSKKFEKLGQPVWQMIWLSLASFFWFIPLALWAGPYFFDGHPSALLEIEYFKYLLCFGPLAALS
GAISAFYIGQGQVKCVTCVMAVSNLVNIGLDYLLIFGWEPWIPALGIKGAAIATGIALTVQVVIFGWDFFKASNRKEKGT
NKWRINKRLFRKSLSIGIPNAFAHTLELMAWVLIFHLMTKLGTDYITVVTVAQSIFFLFTFMTEGVSKGATAIAANFFGA
EQHELVWKLLKSGLKLYLFVFLLLGVILVWYPDPLIHLFLVQKEALSPAVLSTLHAACFWVWLFFLFDGINWLLVGLLTA
AGDTRFIMKVGGTGPWIVALLPIYFFVFKWGAPANIAWMLIALYGVVSSLIYLWRFKTEKWKYAFVT
>Mature_467_residues
MMIGDYMMSSPLSPLNLNKLTAYPQGSMGELWQISFPLMLSLMSVSLMLFLDRLFLANYSLEALNASANAGILVQFLQFW
CISTVSVAEIFVGRYNGSKKFEKLGQPVWQMIWLSLASFFWFIPLALWAGPYFFDGHPSALLEIEYFKYLLCFGPLAALS
GAISAFYIGQGQVKCVTCVMAVSNLVNIGLDYLLIFGWEPWIPALGIKGAAIATGIALTVQVVIFGWDFFKASNRKEKGT
NKWRINKRLFRKSLSIGIPNAFAHTLELMAWVLIFHLMTKLGTDYITVVTVAQSIFFLFTFMTEGVSKGATAIAANFFGA
EQHELVWKLLKSGLKLYLFVFLLLGVILVWYPDPLIHLFLVQKEALSPAVLSTLHAACFWVWLFFLFDGINWLLVGLLTA
AGDTRFIMKVGGTGPWIVALLPIYFFVFKWGAPANIAWMLIALYGVVSSLIYLWRFKTEKWKYAFVT

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 52574; Mature: 52574

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIGDYMMSSPLSPLNLNKLTAYPQGSMGELWQISFPLMLSLMSVSLMLFLDRLFLANYS
CCCCCHHHHCCCCCCCCCCEECCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHCCC
LEALNASANAGILVQFLQFWCISTVSVAEIFVGRYNGSKKFEKLGQPVWQMIWLSLASFF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHH
WFIPLALWAGPYFFDGHPSALLEIEYFKYLLCFGPLAALSGAISAFYIGQGQVKCVTCVM
HHHHHHHHCCCCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHH
AVSNLVNIGLDYLLIFGWEPWIPALGIKGAAIATGIALTVQVVIFGWDFFKASNRKEKGT
HHHHHHHHCHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEHHHHHCCCCCCCCC
NKWRINKRLFRKSLSIGIPNAFAHTLELMAWVLIFHLMTKLGTDYITVVTVAQSIFFLFT
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FMTEGVSKGATAIAANFFGAEQHELVWKLLKSGLKLYLFVFLLLGVILVWYPDPLIHLFL
HHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VQKEALSPAVLSTLHAACFWVWLFFLFDGINWLLVGLLTAAGDTRFIMKVGGTGPWIVAL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH
LPIYFFVFKWGAPANIAWMLIALYGVVSSLIYLWRFKTEKWKYAFVT
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure
MMIGDYMMSSPLSPLNLNKLTAYPQGSMGELWQISFPLMLSLMSVSLMLFLDRLFLANYS
CCCCCHHHHCCCCCCCCCCEECCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHCCC
LEALNASANAGILVQFLQFWCISTVSVAEIFVGRYNGSKKFEKLGQPVWQMIWLSLASFF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHH
WFIPLALWAGPYFFDGHPSALLEIEYFKYLLCFGPLAALSGAISAFYIGQGQVKCVTCVM
HHHHHHHHCCCCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHH
AVSNLVNIGLDYLLIFGWEPWIPALGIKGAAIATGIALTVQVVIFGWDFFKASNRKEKGT
HHHHHHHHCHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEHHHHHCCCCCCCCC
NKWRINKRLFRKSLSIGIPNAFAHTLELMAWVLIFHLMTKLGTDYITVVTVAQSIFFLFT
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FMTEGVSKGATAIAANFFGAEQHELVWKLLKSGLKLYLFVFLLLGVILVWYPDPLIHLFL
HHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VQKEALSPAVLSTLHAACFWVWLFFLFDGINWLLVGLLTAAGDTRFIMKVGGTGPWIVAL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH
LPIYFFVFKWGAPANIAWMLIALYGVVSSLIYLWRFKTEKWKYAFVT
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]