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The map label for this gene is lig [H]

Identifier: 46446585

GI number: 46446585

Start: 1149520

End: 1150524

Strand: Reverse

Name: lig [H]

Synonym: pc0951

Alternate gene names: 46446585

Gene position: 1150524-1149520 (Counterclockwise)

Preceding gene: 46446586

Following gene: 46446584

Centisome position: 47.65

GC content: 40.8

Gene sequence:

>1005_bases
ATGGAAATTCCTTTAAAAGTCATTAAACAAGGTTTATATTGCCCAGACGGAGATTTCTTTATTGATGCTTGGCAACCAGT
CCCTCGTTGCATCATCACGCATGCGCATGGCGATCATGCTTATGCTGGTCATGGACACTACATTGCAACTGATGAAACGA
TTAAAATTCTACGGAAAAGAATTGGAGGCGAGTTTGAAAGCGAAGCTTTAACATATAATCAGAAAATCAAACTTGGAAAT
ACATGGGTTTCATTGCATCCAGCAGGGCATATTTTAGGATCGGCGCAAATAAGAATCGAAACACCTGGCTGTGTCACAGT
CATATCGGGTGATTATAAGCGAGCAAAAGATGAAACGTGTTTACCATTTGAAGTAGTTGAATGTGATATTTTCGTCACTG
AATCTACTTTTGCCTTGCCCATTTATCAATGGCCTCATAGTCACACCATTGCCAAACAGATCAAAGAGTGGTGGTTGGAG
AATGCCACTCATGATTACCCTTCTATTTTATTTTGTTATTCACTTGGCAAAGCACAACGGGTTTTGTCGATGTTAGCGGA
CCAAGAAAATTTTGTGTATTTGCATGGAGCTATATGTTCATTGTCAAAAATCTATGCAGAAATGGGAATCAAAATGGCTC
GTTTTAAGCCTGTTTCGGAAGGTGAAAAGGGGATGAAATTTTCTAAAGAGCTTATACTAGCTCCACCTTCGGCAGCGGGA
ACTCCATGGTTGAAACGTTTTCCAAGTTGTCGGACAGCTTTGGCGTCCGGTTGGATGCAAGTAAGGGGAACAAGGCGTCG
CCACGCTTTAGATCGTGGGTTTATTTTATCTGATCATGCAGATTGGAAAGCATTGATTGAAACAATTTCACAAACACAAG
CAAAAATTATTTTAACTACTCACGGGAATGCTTCTACGTTGGCTCAATATTTACGCGAAACGCGAAACCTCGATGCCAGA
GAGTTAAAGGGGCTAGATGTTACTTTAGTGAGTGAGGATCAATGA

Upstream 100 bases:

>100_bases
TTGGCTTCTCAAGATTCTTCTTATATTTCAGGACAAATTTTGCATCCTAATGGGGGAGAAATTATTAATGGTTAAAAAAA
TTGGAATTTAAGGCTCCCAT

Downstream 100 bases:

>100_bases
AAAATTTTTCACTTCTTTTTGAACAGATTGATCAAACACAATCAACGAATGAAAAAGTCTCTTATATTCAAAAATATTTT
GCTGATTCTTCCCCAGCCGA

Product: hypothetical protein

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MEIPLKVIKQGLYCPDGDFFIDAWQPVPRCIITHAHGDHAYAGHGHYIATDETIKILRKRIGGEFESEALTYNQKIKLGN
TWVSLHPAGHILGSAQIRIETPGCVTVISGDYKRAKDETCLPFEVVECDIFVTESTFALPIYQWPHSHTIAKQIKEWWLE
NATHDYPSILFCYSLGKAQRVLSMLADQENFVYLHGAICSLSKIYAEMGIKMARFKPVSEGEKGMKFSKELILAPPSAAG
TPWLKRFPSCRTALASGWMQVRGTRRRHALDRGFILSDHADWKALIETISQTQAKIILTTHGNASTLAQYLRETRNLDAR
ELKGLDVTLVSEDQ

Sequences:

>Translated_334_residues
MEIPLKVIKQGLYCPDGDFFIDAWQPVPRCIITHAHGDHAYAGHGHYIATDETIKILRKRIGGEFESEALTYNQKIKLGN
TWVSLHPAGHILGSAQIRIETPGCVTVISGDYKRAKDETCLPFEVVECDIFVTESTFALPIYQWPHSHTIAKQIKEWWLE
NATHDYPSILFCYSLGKAQRVLSMLADQENFVYLHGAICSLSKIYAEMGIKMARFKPVSEGEKGMKFSKELILAPPSAAG
TPWLKRFPSCRTALASGWMQVRGTRRRHALDRGFILSDHADWKALIETISQTQAKIILTTHGNASTLAQYLRETRNLDAR
ELKGLDVTLVSEDQ
>Mature_334_residues
MEIPLKVIKQGLYCPDGDFFIDAWQPVPRCIITHAHGDHAYAGHGHYIATDETIKILRKRIGGEFESEALTYNQKIKLGN
TWVSLHPAGHILGSAQIRIETPGCVTVISGDYKRAKDETCLPFEVVECDIFVTESTFALPIYQWPHSHTIAKQIKEWWLE
NATHDYPSILFCYSLGKAQRVLSMLADQENFVYLHGAICSLSKIYAEMGIKMARFKPVSEGEKGMKFSKELILAPPSAAG
TPWLKRFPSCRTALASGWMQVRGTRRRHALDRGFILSDHADWKALIETISQTQAKIILTTHGNASTLAQYLRETRNLDAR
ELKGLDVTLVSEDQ

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 37599; Mature: 37599

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIPLKVIKQGLYCPDGDFFIDAWQPVPRCIITHAHGDHAYAGHGHYIATDETIKILRKR
CCCCHHHHHCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCCEEECHHHHHHHHHH
IGGEFESEALTYNQKIKLGNTWVSLHPAGHILGSAQIRIETPGCVTVISGDYKRAKDETC
HCCCCCCCCEEECCEEEECCEEEEECCCCCEECCEEEEEECCCEEEEEECCCHHCCCCCC
LPFEVVECDIFVTESTFALPIYQWPHSHTIAKQIKEWWLENATHDYPSILFCYSLGKAQR
CCEEEEEEEEEEECCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHH
VLSMLADQENFVYLHGAICSLSKIYAEMGIKMARFKPVSEGEKGMKFSKELILAPPSAAG
HHHHHCCCCCEEEEEHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEECCCCCC
TPWLKRFPSCRTALASGWMQVRGTRRRHALDRGFILSDHADWKALIETISQTQAKIILTT
CHHHHHCCHHHHHHHHCHHHHCCCHHHHHHCCCCEEECCCCHHHHHHHHHCCCEEEEEEE
HGNASTLAQYLRETRNLDARELKGLDVTLVSEDQ
CCCHHHHHHHHHHHCCCCHHHHCCCEEEEEECCC
>Mature Secondary Structure
MEIPLKVIKQGLYCPDGDFFIDAWQPVPRCIITHAHGDHAYAGHGHYIATDETIKILRKR
CCCCHHHHHCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCCEEECHHHHHHHHHH
IGGEFESEALTYNQKIKLGNTWVSLHPAGHILGSAQIRIETPGCVTVISGDYKRAKDETC
HCCCCCCCCEEECCEEEECCEEEEECCCCCEECCEEEEEECCCEEEEEECCCHHCCCCCC
LPFEVVECDIFVTESTFALPIYQWPHSHTIAKQIKEWWLENATHDYPSILFCYSLGKAQR
CCEEEEEEEEEEECCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHH
VLSMLADQENFVYLHGAICSLSKIYAEMGIKMARFKPVSEGEKGMKFSKELILAPPSAAG
HHHHHCCCCCEEEEEHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEEEEECCCCCC
TPWLKRFPSCRTALASGWMQVRGTRRRHALDRGFILSDHADWKALIETISQTQAKIILTT
CHHHHHCCHHHHHHHHCHHHHCCCHHHHHHCCCCEEECCCCHHHHHHHHHCCCEEEEEEE
HGNASTLAQYLRETRNLDARELKGLDVTLVSEDQ
CCCHHHHHHHHHHHCCCCHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA