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The map label for this gene is ydjE [C]

Identifier: 46446561

GI number: 46446561

Start: 1119383

End: 1120690

Strand: Reverse

Name: ydjE [C]

Synonym: pc0927

Alternate gene names: 46446561

Gene position: 1120690-1119383 (Counterclockwise)

Preceding gene: 46446562

Following gene: 46446560

Centisome position: 46.42

GC content: 37.16

Gene sequence:

>1308_bases
ATGGCAACAAATAAAATGGGGCTCATGAGCGCAATTTTGCTTGGGATCAATATGATTTTAGGATCGGGAATCTTTCTTCT
CCCTGGAAAAGTTTCTGAATTAACCGGTGCATCTAGTCTGTATGTCTATGTCTTTGTTTCTCTACTTATTTTGTCAATTG
CTTGGTGCTTTGCGCAATGTGCAGCTCTATTCGATCGCAATGGAGGTGCTTATTTATATGCTAAAGAAGCTTTTGGTGAT
TTTATAGGATTTGAAATAGGTTTTATGCGATGGATTGCTGGAGCGATGGCTTGGGCTTCGCTTATTGTAGGTTTTGTTAC
AGCTCTGAGTTCTATTTGGCCAAATGCATTGACAGAGCCTTTAAGGGGATTTTTGATCTTAATTTTTTTAGCTCTTCTTA
TTTTATTTAATATGGGAGGAACTGAAAAACTTAAAAATATCAACAATGTCGTGACGATAGCAAAGGTATTACCTCTTCTA
TTTTTTGTTTTGATTGGTTTTTTTTATACTAAGGGGAACTTTCAAGCGATTGATGTGTCATTATCCCATTTAGATTCTAT
TTCTTTTGGAAATGCCGCTATAGTTATTTTTTATGCTTTTGGAGGGTTTGAAACTCTTGTTATTGCTGCAGGAGAAATAA
AAAATCCTCACCGTAACTTACCAATAGCGGTGATGGCTGTTATTAGCTTTTGCTCGTTTCTATATTTTTTAATTCAAATA
ATTGCCATGGAGATATTAGGACCTCACTTGGCTGAAAGTTCTATTCCTTTAGCTGATGCGACTGAACAAATGATTGGGTC
CGCTGGGAGATGGATTGTAACTTTAGGTATGATTATTTCGATTGGAGGTGTGAATCTTACAGCTTCTTTTATTACTCCAA
GAAGTGGAGCGGCTTTAGCAGAAGATGGTTTGGTTCCCAGATGGATCGCCAAAAATAATAAAGCCGGTGTTCCCGTAGTA
GCTATCTTCTTGACAGCAAGTTTGACTACCATTGCTGCTTTGTCAGGGAGTTTTACTCAGCTAGCTGTGATCAGCGTTGT
CTCTCGATTTGTACAGTATGGAGCGACATGTTTAGCTGTTTTTGTCCTTTATTATCGCAATAGGGCAACATTAAAAATGT
TAAAAAAAATATCTCTGGTTATTATTCCTTCGTTATCTTTGATTGGTCTTATTTGGATGTTATTTCAAGCTTCTTCTTCT
CAGTTATATTGGGGCCTAGGGGCGCTCCTGCCTGGAATTCCCATTTATTTTTTTCAGAAGTGGAAAAATAATTTAACGTT
AGCGACAGTTTCTGAAATGGGTGATTAA

Upstream 100 bases:

>100_bases
ATTGGTGTACAATGGCACCCAGAATTAATGGCCGATAAACAAGAAGAAACGCGAAAGCTCTTTGAGGGTTTAGTCAAAGC
TAGTCAATAGGGAGAAAACG

Downstream 100 bases:

>100_bases
ATATCATAAATAAATATTTATCATTTTCAACTTTTTAATGGGTAGATTTAACTAAATTTAAATAACTATAGACAATTTCC
AGTTTAAATTATATTTAAAG

Product: putative cationic amino acid transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MATNKMGLMSAILLGINMILGSGIFLLPGKVSELTGASSLYVYVFVSLLILSIAWCFAQCAALFDRNGGAYLYAKEAFGD
FIGFEIGFMRWIAGAMAWASLIVGFVTALSSIWPNALTEPLRGFLILIFLALLILFNMGGTEKLKNINNVVTIAKVLPLL
FFVLIGFFYTKGNFQAIDVSLSHLDSISFGNAAIVIFYAFGGFETLVIAAGEIKNPHRNLPIAVMAVISFCSFLYFLIQI
IAMEILGPHLAESSIPLADATEQMIGSAGRWIVTLGMIISIGGVNLTASFITPRSGAALAEDGLVPRWIAKNNKAGVPVV
AIFLTASLTTIAALSGSFTQLAVISVVSRFVQYGATCLAVFVLYYRNRATLKMLKKISLVIIPSLSLIGLIWMLFQASSS
QLYWGLGALLPGIPIYFFQKWKNNLTLATVSEMGD

Sequences:

>Translated_435_residues
MATNKMGLMSAILLGINMILGSGIFLLPGKVSELTGASSLYVYVFVSLLILSIAWCFAQCAALFDRNGGAYLYAKEAFGD
FIGFEIGFMRWIAGAMAWASLIVGFVTALSSIWPNALTEPLRGFLILIFLALLILFNMGGTEKLKNINNVVTIAKVLPLL
FFVLIGFFYTKGNFQAIDVSLSHLDSISFGNAAIVIFYAFGGFETLVIAAGEIKNPHRNLPIAVMAVISFCSFLYFLIQI
IAMEILGPHLAESSIPLADATEQMIGSAGRWIVTLGMIISIGGVNLTASFITPRSGAALAEDGLVPRWIAKNNKAGVPVV
AIFLTASLTTIAALSGSFTQLAVISVVSRFVQYGATCLAVFVLYYRNRATLKMLKKISLVIIPSLSLIGLIWMLFQASSS
QLYWGLGALLPGIPIYFFQKWKNNLTLATVSEMGD
>Mature_434_residues
ATNKMGLMSAILLGINMILGSGIFLLPGKVSELTGASSLYVYVFVSLLILSIAWCFAQCAALFDRNGGAYLYAKEAFGDF
IGFEIGFMRWIAGAMAWASLIVGFVTALSSIWPNALTEPLRGFLILIFLALLILFNMGGTEKLKNINNVVTIAKVLPLLF
FVLIGFFYTKGNFQAIDVSLSHLDSISFGNAAIVIFYAFGGFETLVIAAGEIKNPHRNLPIAVMAVISFCSFLYFLIQII
AMEILGPHLAESSIPLADATEQMIGSAGRWIVTLGMIISIGGVNLTASFITPRSGAALAEDGLVPRWIAKNNKAGVPVVA
IFLTASLTTIAALSGSFTQLAVISVVSRFVQYGATCLAVFVLYYRNRATLKMLKKISLVIIPSLSLIGLIWMLFQASSSQ
LYWGLGALLPGIPIYFFQKWKNNLTLATVSEMGD

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI114326544, Length=410, Percent_Identity=22.6829268292683, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI114326550, Length=410, Percent_Identity=22.6829268292683, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI258614005, Length=416, Percent_Identity=23.5576923076923, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI258614003, Length=416, Percent_Identity=23.5576923076923, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI258645169, Length=415, Percent_Identity=23.6144578313253, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4507047, Length=400, Percent_Identity=23.5, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI110347453, Length=328, Percent_Identity=27.7439024390244, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI181337167, Length=385, Percent_Identity=23.8961038961039, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI33286428, Length=445, Percent_Identity=25.6179775280899, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI71979932, Length=442, Percent_Identity=23.9819004524887, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI187423910, Length=411, Percent_Identity=23.3576642335766, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI7657591, Length=411, Percent_Identity=23.3576642335766, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI115648063, Length=451, Percent_Identity=23.2815964523282, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI115648022, Length=451, Percent_Identity=23.2815964523282, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI2367353, Length=416, Percent_Identity=26.9230769230769, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1786908, Length=361, Percent_Identity=24.0997229916898, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787890, Length=345, Percent_Identity=25.2173913043478, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082250, Length=346, Percent_Identity=25.7225433526012, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790575, Length=338, Percent_Identity=21.8934911242604, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=392, Percent_Identity=24.7448979591837, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71993915, Length=436, Percent_Identity=24.0825688073394, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17540018, Length=441, Percent_Identity=24.2630385487528, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17533459, Length=385, Percent_Identity=23.3766233766234, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17532491, Length=383, Percent_Identity=25.065274151436, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71995388, Length=397, Percent_Identity=26.7002518891688, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71995382, Length=397, Percent_Identity=26.7002518891688, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32566695, Length=411, Percent_Identity=22.8710462287105, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193208714, Length=411, Percent_Identity=22.8710462287105, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17568033, Length=442, Percent_Identity=24.4343891402715, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221512776, Length=383, Percent_Identity=25.5874673629243, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666159, Length=383, Percent_Identity=25.5874673629243, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281366235, Length=392, Percent_Identity=23.2142857142857, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI116007820, Length=392, Percent_Identity=23.2142857142857, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24668806, Length=406, Percent_Identity=22.9064039408867, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356285, Length=406, Percent_Identity=22.9064039408867, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24668802, Length=406, Percent_Identity=22.9064039408867, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667468, Length=376, Percent_Identity=22.8723404255319, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI116007818, Length=390, Percent_Identity=23.3333333333333, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI85725152, Length=390, Percent_Identity=23.3333333333333, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221331183, Length=444, Percent_Identity=23.6486486486486, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17647653, Length=444, Percent_Identity=23.6486486486486, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24664379, Length=444, Percent_Identity=23.6486486486486, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45550968, Length=430, Percent_Identity=24.1860465116279, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19921172, Length=430, Percent_Identity=24.1860465116279, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24651635, Length=443, Percent_Identity=24.6049661399549, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24651633, Length=443, Percent_Identity=24.6049661399549, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357367, Length=459, Percent_Identity=22.6579520697168, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 46975; Mature: 46843

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATNKMGLMSAILLGINMILGSGIFLLPGKVSELTGASSLYVYVFVSLLILSIAWCFAQC
CCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AALFDRNGGAYLYAKEAFGDFIGFEIGFMRWIAGAMAWASLIVGFVTALSSIWPNALTEP
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LRGFLILIFLALLILFNMGGTEKLKNINNVVTIAKVLPLLFFVLIGFFYTKGNFQAIDVS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LSHLDSISFGNAAIVIFYAFGGFETLVIAAGEIKNPHRNLPIAVMAVISFCSFLYFLIQI
HHHHCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IAMEILGPHLAESSIPLADATEQMIGSAGRWIVTLGMIISIGGVNLTASFITPRSGAALA
HHHHHHCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHH
EDGLVPRWIAKNNKAGVPVVAIFLTASLTTIAALSGSFTQLAVISVVSRFVQYGATCLAV
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FVLYYRNRATLKMLKKISLVIIPSLSLIGLIWMLFQASSSQLYWGLGALLPGIPIYFFQK
HHHHHCCHHHHHHHHHHHHHEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHH
WKNNLTLATVSEMGD
HCCCCEEEEHHCCCC
>Mature Secondary Structure 
ATNKMGLMSAILLGINMILGSGIFLLPGKVSELTGASSLYVYVFVSLLILSIAWCFAQC
CCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AALFDRNGGAYLYAKEAFGDFIGFEIGFMRWIAGAMAWASLIVGFVTALSSIWPNALTEP
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LRGFLILIFLALLILFNMGGTEKLKNINNVVTIAKVLPLLFFVLIGFFYTKGNFQAIDVS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LSHLDSISFGNAAIVIFYAFGGFETLVIAAGEIKNPHRNLPIAVMAVISFCSFLYFLIQI
HHHHCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IAMEILGPHLAESSIPLADATEQMIGSAGRWIVTLGMIISIGGVNLTASFITPRSGAALA
HHHHHHCHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHH
EDGLVPRWIAKNNKAGVPVVAIFLTASLTTIAALSGSFTQLAVISVVSRFVQYGATCLAV
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FVLYYRNRATLKMLKKISLVIIPSLSLIGLIWMLFQASSSQLYWGLGALLPGIPIYFFQK
HHHHHCCHHHHHHHHHHHHHEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHH
WKNNLTLATVSEMGD
HCCCCEEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]