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The map label for this gene is htpX [H]

Identifier: 46446535

GI number: 46446535

Start: 1092119

End: 1093099

Strand: Direct

Name: htpX [H]

Synonym: pc0901

Alternate gene names: 46446535

Gene position: 1092119-1093099 (Clockwise)

Preceding gene: 46446534

Following gene: 46446538

Centisome position: 45.23

GC content: 38.53

Gene sequence:

>981_bases
GTGATGGCCATGAACTTTTGGGAAGCTCAGCGTGAAGCAAAGACAAAAACAACTCTTTATTTAGTGATCTTCTTTATTCT
TACTCTTATCTCAGCAACACTTGCAGAAATATTGATGAGAGGCTTTGCACAAGATGGCTACCATACTGATTTTCCTTATA
TAGGCTTAGGATTTTTAAGTGTTATTTTTTGTGTGGCCGGATTCAATTATATGAATTATTTGCAAAATGGAGGTAGTTAC
GTAGCAGAGTCTTTAGGTGCGAGACTTGTCGACCCTAATACGCGCGATGGTAAAGAAAGGCAATTATTGAATATCGTGGA
AGAAATTGCTTTGGCCACTTCTTTACCTATTCCTCCTGTGTACATTTTAGAAGCTCAAGAAATCAATGCTTTTGCGGCAG
GAACTTCGTACGATAATGCAGCTATAACTGTCACACAAGGATGTTTATTAGCTTTGAATCGAGATGAATTGCAAGGAGTT
TTAGCTCACGAATTCGGGCATATATATAATCGAGATATGCTGATTGGAATGCGTGTTGCGGCTATGATTATGGGATTCTT
TATTGTCTCTTATATTGGACTTAGAATGTTACAAACCGCCCCTTATGCAAGAAGAGATGATAAGGAAGAACGTAAAAGTG
GTAATCCTGTTGCAGCGATAGGTATGATTTTCACGTTAGTGGGAGCATTCATGTGGTTTTTTGGCTCTATTCTTCAAGCC
ATGGTGAGTCGCCAAAGGGAGTATTTAGCGGATGCAAGTTCTGTCCAATATACACGCAATCCTGCAGGGATCTCTAGTGC
TTTAAAGAAGATCCAAAACTATAAACTTTCTGATATGCCAAAAAGTGGAAAACCTTTTGCTCATTTATACTTTAATGAGC
ATACCTCTTTTTGGCAGCGTTTATTCGCGAGTCATCCTCCAATTGAAGATCGTATTGCAGCGATTGAAGGTCATAAATAT
GTGGATCTTAATCAAAAATGA

Upstream 100 bases:

>100_bases
TCATTCAGTGGAATTATTTCAAATTGATGATCAAAAAGCTAAACTAGCTCCAAAAATATCTTTTGATTAAGTAACTTATT
TTAAAAAATAGAAGGATTCA

Downstream 100 bases:

>100_bases
TATTGCATTGCCCTCCCCTGCACTTAATGAAAAATTTCACAAAATTTTACTAAAGCACCTAAACTATCAAAGGAAAAAAT
TAAAATGTCTAGATAGTGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MMAMNFWEAQREAKTKTTLYLVIFFILTLISATLAEILMRGFAQDGYHTDFPYIGLGFLSVIFCVAGFNYMNYLQNGGSY
VAESLGARLVDPNTRDGKERQLLNIVEEIALATSLPIPPVYILEAQEINAFAAGTSYDNAAITVTQGCLLALNRDELQGV
LAHEFGHIYNRDMLIGMRVAAMIMGFFIVSYIGLRMLQTAPYARRDDKEERKSGNPVAAIGMIFTLVGAFMWFFGSILQA
MVSRQREYLADASSVQYTRNPAGISSALKKIQNYKLSDMPKSGKPFAHLYFNEHTSFWQRLFASHPPIEDRIAAIEGHKY
VDLNQK

Sequences:

>Translated_326_residues
MMAMNFWEAQREAKTKTTLYLVIFFILTLISATLAEILMRGFAQDGYHTDFPYIGLGFLSVIFCVAGFNYMNYLQNGGSY
VAESLGARLVDPNTRDGKERQLLNIVEEIALATSLPIPPVYILEAQEINAFAAGTSYDNAAITVTQGCLLALNRDELQGV
LAHEFGHIYNRDMLIGMRVAAMIMGFFIVSYIGLRMLQTAPYARRDDKEERKSGNPVAAIGMIFTLVGAFMWFFGSILQA
MVSRQREYLADASSVQYTRNPAGISSALKKIQNYKLSDMPKSGKPFAHLYFNEHTSFWQRLFASHPPIEDRIAAIEGHKY
VDLNQK
>Mature_326_residues
MMAMNFWEAQREAKTKTTLYLVIFFILTLISATLAEILMRGFAQDGYHTDFPYIGLGFLSVIFCVAGFNYMNYLQNGGSY
VAESLGARLVDPNTRDGKERQLLNIVEEIALATSLPIPPVYILEAQEINAFAAGTSYDNAAITVTQGCLLALNRDELQGV
LAHEFGHIYNRDMLIGMRVAAMIMGFFIVSYIGLRMLQTAPYARRDDKEERKSGNPVAAIGMIFTLVGAFMWFFGSILQA
MVSRQREYLADASSVQYTRNPAGISSALKKIQNYKLSDMPKSGKPFAHLYFNEHTSFWQRLFASHPPIEDRIAAIEGHKY
VDLNQK

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=258, Percent_Identity=30.2325581395349, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 36610; Mature: 36610

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAMNFWEAQREAKTKTTLYLVIFFILTLISATLAEILMRGFAQDGYHTDFPYIGLGFLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VIFCVAGFNYMNYLQNGGSYVAESLGARLVDPNTRDGKERQLLNIVEEIALATSLPIPPV
HHHHHHHHHHHHHHHCCHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCE
YILEAQEINAFAAGTSYDNAAITVTQGCLLALNRDELQGVLAHEFGHIYNRDMLIGMRVA
EEEEHHHCCCEECCCCCCCCEEEEECCHHEEECHHHHHHHHHHHHHHHHCCCHHHHHHHH
AMIMGFFIVSYIGLRMLQTAPYARRDDKEERKSGNPVAAIGMIFTLVGAFMWFFGSILQA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MVSRQREYLADASSVQYTRNPAGISSALKKIQNYKLSDMPKSGKPFAHLYFNEHTSFWQR
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHH
LFASHPPIEDRIAAIEGHKYVDLNQK
HHHCCCCHHHHHHHHCCCEEECCCCC
>Mature Secondary Structure
MMAMNFWEAQREAKTKTTLYLVIFFILTLISATLAEILMRGFAQDGYHTDFPYIGLGFLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VIFCVAGFNYMNYLQNGGSYVAESLGARLVDPNTRDGKERQLLNIVEEIALATSLPIPPV
HHHHHHHHHHHHHHHCCHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCE
YILEAQEINAFAAGTSYDNAAITVTQGCLLALNRDELQGVLAHEFGHIYNRDMLIGMRVA
EEEEHHHCCCEECCCCCCCCEEEEECCHHEEECHHHHHHHHHHHHHHHHCCCHHHHHHHH
AMIMGFFIVSYIGLRMLQTAPYARRDDKEERKSGNPVAAIGMIFTLVGAFMWFFGSILQA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MVSRQREYLADASSVQYTRNPAGISSALKKIQNYKLSDMPKSGKPFAHLYFNEHTSFWQR
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHH
LFASHPPIEDRIAAIEGHKYVDLNQK
HHHCCCCHHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]