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The map label for this gene is gseA [H]

Identifier: 46446461

GI number: 46446461

Start: 1012343

End: 1013596

Strand: Direct

Name: gseA [H]

Synonym: pc0827

Alternate gene names: 46446461

Gene position: 1012343-1013596 (Clockwise)

Preceding gene: 46446460

Following gene: 46446462

Centisome position: 41.93

GC content: 35.49

Gene sequence:

>1254_bases
ATGCTTTATTATTTTTTTATTCACGGGAAATACCGACACAGCTTGTGGTATCGATTAGGATTTAAAGGGTTTGAAATCAG
TCAAGAACACCCTTTGATTTGGATTCATGCTGTATCTCTTGGAGAGACGAAAGCCGTTATCGCTTTAGCGCGAGAATTAA
AACTTACTTATCCTCATCATCGCTTACTTATTTCTTCGGTGACAGAAACTGGTCATGCTGAAGCAAAAAGGAGTTTGCCT
TTTGCCAATTATCATGTTTATTTACCCTTCGATTTTTATTTCATTATAAAAAAAATCGTCCGAAAAACGGCCCCCCAGCT
CGTGATTATTTGTGAATCCGACTTTTGGTTGAATTTTATGAGACTAACTAAGCAAGAGGGAGCTGCACTTGTTTTAGTTA
ATGGTAAGTTATCTCAAAAATCTGCGGCACGTTTTAAAGTATTTAATTTTTTCTCTAAAAAACTTTTTAGTTTGTTCGAT
CTTCTATGCGTTCAAAATTCTTTATATAAAGAACGTTTTGTTGATATTGGTGTACAGGAAGAAAAATTACATGTGACTGG
AAACCTTAAATTAGATGATGAGTATCCACAACTGACAAAAGAAGGGGTGTATGCATGGAGAGAAAAATTGGGAATTTCTC
CGGAGCAACCCGTCTTAACAATTGGTTCTTCACATTATCCAGAAGAACAAATGCTTATTCGCATGCTTAAAGAACTCTGG
AATCAAATTCCTGATTTAAAAGCTATTTTAGTGCCTCGTCATCCTGAAAGATTTAAGGAAGTGGTTGCTTTTTTAGAAAA
GGAACGACTCAAGTGGATTAATTTTACAGATATCAATAGGAGAACTGGAAAAGAGCAAGTTATTCTTATTGATGCGATGG
GAATGCTTCGCATGTGTTACCAACTTTCGGATATTGCAATTGTTGGGGGGAGTTTTACATTAAAGGTAGGTGGACATAAC
ATCCTAGAGCCTTGTTGGTATGGTAAACCTGTTATTTTTGGACTTTCTATGTATTCGCAATTAGAACTTGTTGACCTTAT
TAAACAAGCTGAAGCTGGGATTCAAGTTTCAGAGCAAGAATTACAAAAAGTTTTAGAAATTTTATTAATTGACAGTTCTA
TCCGAGAAGAAATTGGTCAGAACGGATTAGCACTTGTCCAAAGTTTGAGAGGGTCAACAAAACGAACACTGCAAACTATC
ACAAATCTTTTCCAAAAATTTAAATTCCCTTCGACAGATACATTAAAGGCTTAG

Upstream 100 bases:

>100_bases
AATTTATTAATTTTAAACTTTTGAGATCAGAGTGAAGCGTCTTTTCTTTCTCCTATATGAAATGTCATTATGGCTATTAG
CTATTTTAGCATCTCCCAAA

Downstream 100 bases:

>100_bases
TAAAGCTTATTTTTGTAAATAATAGAAATTATAGTTGTTTGAAAATAACGCATTTGCTATAGTCAATGTTTCTTTAGCAA
ACTAAAACCCAGTTTGCATC

Product: putative 3-deoxy-manno-octulosonate

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MLYYFFIHGKYRHSLWYRLGFKGFEISQEHPLIWIHAVSLGETKAVIALARELKLTYPHHRLLISSVTETGHAEAKRSLP
FANYHVYLPFDFYFIIKKIVRKTAPQLVIICESDFWLNFMRLTKQEGAALVLVNGKLSQKSAARFKVFNFFSKKLFSLFD
LLCVQNSLYKERFVDIGVQEEKLHVTGNLKLDDEYPQLTKEGVYAWREKLGISPEQPVLTIGSSHYPEEQMLIRMLKELW
NQIPDLKAILVPRHPERFKEVVAFLEKERLKWINFTDINRRTGKEQVILIDAMGMLRMCYQLSDIAIVGGSFTLKVGGHN
ILEPCWYGKPVIFGLSMYSQLELVDLIKQAEAGIQVSEQELQKVLEILLIDSSIREEIGQNGLALVQSLRGSTKRTLQTI
TNLFQKFKFPSTDTLKA

Sequences:

>Translated_417_residues
MLYYFFIHGKYRHSLWYRLGFKGFEISQEHPLIWIHAVSLGETKAVIALARELKLTYPHHRLLISSVTETGHAEAKRSLP
FANYHVYLPFDFYFIIKKIVRKTAPQLVIICESDFWLNFMRLTKQEGAALVLVNGKLSQKSAARFKVFNFFSKKLFSLFD
LLCVQNSLYKERFVDIGVQEEKLHVTGNLKLDDEYPQLTKEGVYAWREKLGISPEQPVLTIGSSHYPEEQMLIRMLKELW
NQIPDLKAILVPRHPERFKEVVAFLEKERLKWINFTDINRRTGKEQVILIDAMGMLRMCYQLSDIAIVGGSFTLKVGGHN
ILEPCWYGKPVIFGLSMYSQLELVDLIKQAEAGIQVSEQELQKVLEILLIDSSIREEIGQNGLALVQSLRGSTKRTLQTI
TNLFQKFKFPSTDTLKA
>Mature_417_residues
MLYYFFIHGKYRHSLWYRLGFKGFEISQEHPLIWIHAVSLGETKAVIALARELKLTYPHHRLLISSVTETGHAEAKRSLP
FANYHVYLPFDFYFIIKKIVRKTAPQLVIICESDFWLNFMRLTKQEGAALVLVNGKLSQKSAARFKVFNFFSKKLFSLFD
LLCVQNSLYKERFVDIGVQEEKLHVTGNLKLDDEYPQLTKEGVYAWREKLGISPEQPVLTIGSSHYPEEQMLIRMLKELW
NQIPDLKAILVPRHPERFKEVVAFLEKERLKWINFTDINRRTGKEQVILIDAMGMLRMCYQLSDIAIVGGSFTLKVGGHN
ILEPCWYGKPVIFGLSMYSQLELVDLIKQAEAGIQVSEQELQKVLEILLIDSSIREEIGQNGLALVQSLRGSTKRTLQTI
TNLFQKFKFPSTDTLKA

Specific function: Transfers three 3-deoxy-D-mono octulonic acid (KDO) individually from CMP-KDO to a tetraacyldisaccharide 1,4'- bisphosphate precursor of lipid A (lipid IVA) [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=408, Percent_Identity=32.1078431372549, Blast_Score=205, Evalue=5e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007507 [H]

Pfam domain/function: PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 48207; Mature: 48207

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYYFFIHGKYRHSLWYRLGFKGFEISQEHPLIWIHAVSLGETKAVIALARELKLTYPHH
CEEEEEEECCHHHHHHEEECCCCCEECCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCHH
RLLISSVTETGHAEAKRSLPFANYHVYLPFDFYFIIKKIVRKTAPQLVIICESDFWLNFM
HHHHHHHHHCCCHHHHHCCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
RLTKQEGAALVLVNGKLSQKSAARFKVFNFFSKKLFSLFDLLCVQNSLYKERFVDIGVQE
HHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EKLHVTGNLKLDDEYPQLTKEGVYAWREKLGISPEQPVLTIGSSHYPEEQMLIRMLKELW
CEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHH
NQIPDLKAILVPRHPERFKEVVAFLEKERLKWINFTDINRRTGKEQVILIDAMGMLRMCY
HHCCCCEEEECCCCHHHHHHHHHHHHHHHCCEECEECCCCCCCCCEEEEEEHHHHHHHHH
QLSDIAIVGGSFTLKVGGHNILEPCWYGKPVIFGLSMYSQLELVDLIKQAEAGIQVSEQE
HHCCEEEECCEEEEEECCCCCCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCEECHHH
LQKVLEILLIDSSIREEIGQNGLALVQSLRGSTKRTLQTITNLFQKFKFPSTDTLKA
HHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLYYFFIHGKYRHSLWYRLGFKGFEISQEHPLIWIHAVSLGETKAVIALARELKLTYPHH
CEEEEEEECCHHHHHHEEECCCCCEECCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCHH
RLLISSVTETGHAEAKRSLPFANYHVYLPFDFYFIIKKIVRKTAPQLVIICESDFWLNFM
HHHHHHHHHCCCHHHHHCCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
RLTKQEGAALVLVNGKLSQKSAARFKVFNFFSKKLFSLFDLLCVQNSLYKERFVDIGVQE
HHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EKLHVTGNLKLDDEYPQLTKEGVYAWREKLGISPEQPVLTIGSSHYPEEQMLIRMLKELW
CEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHH
NQIPDLKAILVPRHPERFKEVVAFLEKERLKWINFTDINRRTGKEQVILIDAMGMLRMCY
HHCCCCEEEECCCCHHHHHHHHHHHHHHHCCEECEECCCCCCCCCEEEEEEHHHHHHHHH
QLSDIAIVGGSFTLKVGGHNILEPCWYGKPVIFGLSMYSQLELVDLIKQAEAGIQVSEQE
HHCCEEEECCEEEEEECCCCCCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCEECHHH
LQKVLEILLIDSSIREEIGQNGLALVQSLRGSTKRTLQTITNLFQKFKFPSTDTLKA
HHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1382060; 7861960 [H]