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The map label for this gene is fabZ

Identifier: 46446036

GI number: 46446036

Start: 539976

End: 540440

Strand: Direct

Name: fabZ

Synonym: pc0402

Alternate gene names: 46446036

Gene position: 539976-540440 (Clockwise)

Preceding gene: 46446035

Following gene: 46446037

Centisome position: 22.36

GC content: 40.0

Gene sequence:

>465_bases
ATGGTTAATCTTTCAGATAACCCACAGGCATTGGATATCAATCAAATCATCAATATTTTACCCCACCGTTATCCTTTTCT
GCTTGTCGATCGTGTCTTAGAAATCGATGTAGAAAAAGGATATATCCTAGCGCAAAAAAACGTAACAATTAACGAGTCTT
TTTTTCAAGGTCATTTCCCTAATGCTCCAATCATGCCAGGCGTTTTGATTTTAGAGGCGTTAGCTCAGGCGGGTGGTATT
TTGGTTCATTTGAGAGGGCCGGGAGATAAAATTGCAATTTTGCTTAATGTCAATCACGCTAAATTTAGACAGCCCGTGAA
ACCAGGCGATGTTCTCCATTTGAAAGGCGAAGGATTGCATTTTAGTAGCAAGGGGGGGCGAATTAAAGCTGAAGCACTAG
TGAACCAAAAAATTGCAGCCGAGGCTGAAATAGGCTTTGTGTTTGTAGACAAAAGTCAAATTTAA

Upstream 100 bases:

>100_bases
ATGATTTCCATGCTCACATCATTGCGATTCGATCGGGACATTTGACAAACTTTCTTTTTGCTAAAGAATTATTAAAACAT
ATCACTATGGAGAGTCATTG

Downstream 100 bases:

>100_bases
TACACATCTCAAAAAATTAAAATATTTTAAGTTAAGTGAATGTTGCATGAAAAGTTCTTGTCAAATACACCCAACAGCTA
TTATTGCGCCTGGAGTGGTT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MVNLSDNPQALDINQIINILPHRYPFLLVDRVLEIDVEKGYILAQKNVTINESFFQGHFPNAPIMPGVLILEALAQAGGI
LVHLRGPGDKIAILLNVNHAKFRQPVKPGDVLHLKGEGLHFSSKGGRIKAEALVNQKIAAEAEIGFVFVDKSQI

Sequences:

>Translated_154_residues
MVNLSDNPQALDINQIINILPHRYPFLLVDRVLEIDVEKGYILAQKNVTINESFFQGHFPNAPIMPGVLILEALAQAGGI
LVHLRGPGDKIAILLNVNHAKFRQPVKPGDVLHLKGEGLHFSSKGGRIKAEALVNQKIAAEAEIGFVFVDKSQI
>Mature_154_residues
MVNLSDNPQALDINQIINILPHRYPFLLVDRVLEIDVEKGYILAQKNVTINESFFQGHFPNAPIMPGVLILEALAQAGGI
LVHLRGPGDKIAILLNVNHAKFRQPVKPGDVLHLKGEGLHFSSKGGRIKAEALVNQKIAAEAEIGFVFVDKSQI

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=145, Percent_Identity=44.8275862068966, Blast_Score=119, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_PARUW (Q6ME73)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007401.1
- ProteinModelPortal:   Q6ME73
- SMR:   Q6ME73
- STRING:   Q6ME73
- GeneID:   2780878
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0402
- NMPDR:   fig|264201.1.peg.402
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   ILQANIQ
- ProtClustDB:   PRK00006
- BioCyc:   CPRO264201:PC0402-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16887; Mature: 16887

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: ACT_SITE 58-58

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLSDNPQALDINQIINILPHRYPFLLVDRVLEIDVEKGYILAQKNVTINESFFQGHFP
CCCCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHEEECCCCEEEEECCCEECCHHHCCCCC
NAPIMPGVLILEALAQAGGILVHLRGPGDKIAILLNVNHAKFRQPVKPGDVLHLKGEGLH
CCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCHHHHCCCCCCCCEEEEECCCEE
FSSKGGRIKAEALVNQKIAAEAEIGFVFVDKSQI
ECCCCCEEEHHHHHCCHHCCCCEEEEEEEECCCC
>Mature Secondary Structure
MVNLSDNPQALDINQIINILPHRYPFLLVDRVLEIDVEKGYILAQKNVTINESFFQGHFP
CCCCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHEEECCCCEEEEECCCEECCHHHCCCCC
NAPIMPGVLILEALAQAGGILVHLRGPGDKIAILLNVNHAKFRQPVKPGDVLHLKGEGLH
CCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCHHHHCCCCCCCCEEEEECCCEE
FSSKGGRIKAEALVNQKIAAEAEIGFVFVDKSQI
ECCCCCEEEHHHHHCCHHCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA