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The map label for this gene is mip [H]

Identifier: 46446017

GI number: 46446017

Start: 508641

End: 509513

Strand: Reverse

Name: mip [H]

Synonym: pc0383

Alternate gene names: 46446017

Gene position: 509513-508641 (Counterclockwise)

Preceding gene: 46446018

Following gene: 46446016

Centisome position: 21.1

GC content: 37.8

Gene sequence:

>873_bases
ATGTTCAAACAGACAAAATTATTAGCTCTAGCTAGCTTTGGAATGTTTATCGGATGTGGTGTCTTGCATGCTAATGATGC
CAATATAGCAACAAATCAGACTAATAAAAGTGTTCAAGCTTCGACTGAAACACCAAAATCTGATCAAATTGACATGCAAA
AACTTTCTGAAGCTTTCGGCCATTTTATCGGCCGAAATTTACAAGCCCCTGGCTTGCAATTTGACTTAGAAGCTATTATC
AAAGGGATTCGTGAAGGTGCAGCTGGAAAACCTGCCCCTCTTTCAGAAAAAGAATATGAAGAAATGATGGCAGCAGTTCA
AGAAAGAGCATTTAAAGAAATGTCAACAAAGAACTTAAAAAATGCCAATGATTTTATGATAAAAAATAGCCAAAGTACAG
ATGTCACTGAGATCGTTCCGGGCAAACTGCAGTATTCAGTAGAAAAAGAAGGAACAGGGCCAGTCGTTGAACCTCACTCT
TCTCCAAAAATTCATTATACAGGAAAATACCAAGATGGAACTGTGTTTGGAACTTCTGAAGAAATGGACGGTCCTATTAC
CATTCCTCTTGATCAAACAATCCCTGGCTTTAGCAAAGGAATTGTAGGAATGAAAGAAGGAGAAAAAAGACGTCTTTACG
TTCATCCTGATCTCGGATACGGAACGACCGGACAACTTCCTCCAAACGAACTTTTAATTTTTGACATTGAAGTGATAAAA
GCCAACTCAGACGATGCGAAAACTAAAACAGGTAAATCTGCTGATGATGCGGATGAAGAAGATCTTTTTATCGATGAAGA
AGAATATGAACTTGAGCCCGCTCAAAAAAATGCAAAAACACCAGAAGCTTCAAATACTTCTGCTAAAAATTAA

Upstream 100 bases:

>100_bases
AACTTAAAGAATTAGAAATACGTGTACCTGACTCTCAATTTTCTTGGACTTAATTCGTGAGATTGCCTACAGTAATATTC
TTTCAAATGGAGGTCTATTT

Downstream 100 bases:

>100_bases
TAAATTGCATTAACTCCGATCTCATTGAAAATTTGCAAGACTTTAGGCTTGCAAATTTTCATTAAATTTCCTTTTCCTCT
ATGAAAATTATTTTATTCCA

Product: putative MIP (macrophage infectivity potentiator, fkbp-type peptidyl-prolyl cis-trans isomerase)

Products: NA

Alternate protein names: PPIase; 27 kDa membrane protein; Chl-Mip; Rotamase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MFKQTKLLALASFGMFIGCGVLHANDANIATNQTNKSVQASTETPKSDQIDMQKLSEAFGHFIGRNLQAPGLQFDLEAII
KGIREGAAGKPAPLSEKEYEEMMAAVQERAFKEMSTKNLKNANDFMIKNSQSTDVTEIVPGKLQYSVEKEGTGPVVEPHS
SPKIHYTGKYQDGTVFGTSEEMDGPITIPLDQTIPGFSKGIVGMKEGEKRRLYVHPDLGYGTTGQLPPNELLIFDIEVIK
ANSDDAKTKTGKSADDADEEDLFIDEEEYELEPAQKNAKTPEASNTSAKN

Sequences:

>Translated_290_residues
MFKQTKLLALASFGMFIGCGVLHANDANIATNQTNKSVQASTETPKSDQIDMQKLSEAFGHFIGRNLQAPGLQFDLEAII
KGIREGAAGKPAPLSEKEYEEMMAAVQERAFKEMSTKNLKNANDFMIKNSQSTDVTEIVPGKLQYSVEKEGTGPVVEPHS
SPKIHYTGKYQDGTVFGTSEEMDGPITIPLDQTIPGFSKGIVGMKEGEKRRLYVHPDLGYGTTGQLPPNELLIFDIEVIK
ANSDDAKTKTGKSADDADEEDLFIDEEEYELEPAQKNAKTPEASNTSAKN
>Mature_290_residues
MFKQTKLLALASFGMFIGCGVLHANDANIATNQTNKSVQASTETPKSDQIDMQKLSEAFGHFIGRNLQAPGLQFDLEAII
KGIREGAAGKPAPLSEKEYEEMMAAVQERAFKEMSTKNLKNANDFMIKNSQSTDVTEIVPGKLQYSVEKEGTGPVVEPHS
SPKIHYTGKYQDGTVFGTSEEMDGPITIPLDQTIPGFSKGIVGMKEGEKRRLYVHPDLGYGTTGQLPPNELLIFDIEVIK
ANSDDAKTKTGKSADDADEEDLFIDEEEYELEPAQKNAKTPEASNTSAKN

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=82, Percent_Identity=41.4634146341463, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI17149844, Length=82, Percent_Identity=41.4634146341463, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI17149842, Length=82, Percent_Identity=41.4634146341463, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082390, Length=208, Percent_Identity=31.25, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789745, Length=205, Percent_Identity=29.2682926829268, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17540882, Length=110, Percent_Identity=36.3636363636364, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281363946, Length=108, Percent_Identity=38.8888888888889, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17352457, Length=108, Percent_Identity=38.8888888888889, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356629, Length=83, Percent_Identity=40.9638554216867, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR000774 [H]

Pfam domain/function: PF00254 FKBP_C; PF01346 FKBP_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 31683; Mature: 31683

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKQTKLLALASFGMFIGCGVLHANDANIATNQTNKSVQASTETPKSDQIDMQKLSEAFG
CCCCHHHHHHHHHHHHHHCEEEECCCCCEEECCCCCCEEECCCCCCCCCHHHHHHHHHHH
HFIGRNLQAPGLQFDLEAIIKGIREGAAGKPAPLSEKEYEEMMAAVQERAFKEMSTKNLK
HHHCCCCCCCCCEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NANDFMIKNSQSTDVTEIVPGKLQYSVEKEGTGPVVEPHSSPKIHYTGKYQDGTVFGTSE
CCCCEEEECCCCCCHHHHCCCCEEEEEECCCCCCEECCCCCCEEEEECCCCCCEEEECCC
EMDGPITIPLDQTIPGFSKGIVGMKEGEKRRLYVHPDLGYGTTGQLPPNELLIFDIEVIK
CCCCCEEEECCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEE
ANSDDAKTKTGKSADDADEEDLFIDEEEYELEPAQKNAKTPEASNTSAKN
CCCCCCCCCCCCCCCCCCCCCEEECCHHCCCCCCHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MFKQTKLLALASFGMFIGCGVLHANDANIATNQTNKSVQASTETPKSDQIDMQKLSEAFG
CCCCHHHHHHHHHHHHHHCEEEECCCCCEEECCCCCCEEECCCCCCCCCHHHHHHHHHHH
HFIGRNLQAPGLQFDLEAIIKGIREGAAGKPAPLSEKEYEEMMAAVQERAFKEMSTKNLK
HHHCCCCCCCCCEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NANDFMIKNSQSTDVTEIVPGKLQYSVEKEGTGPVVEPHSSPKIHYTGKYQDGTVFGTSE
CCCCEEEECCCCCCHHHHCCCCEEEEEECCCCCCEECCCCCCEEEEECCCCCCEEEECCC
EMDGPITIPLDQTIPGFSKGIVGMKEGEKRRLYVHPDLGYGTTGQLPPNELLIFDIEVIK
CCCCCEEEECCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEE
ANSDDAKTKTGKSADDADEEDLFIDEEEYELEPAQKNAKTPEASNTSAKN
CCCCCCCCCCCCCCCCCCCCCEEECCHHCCCCCCHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1406289; 9784136; 2013997 [H]