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The map label for this gene is corA [H]

Identifier: 46445940

GI number: 46445940

Start: 422980

End: 424113

Strand: Reverse

Name: corA [H]

Synonym: pc0306

Alternate gene names: 46445940

Gene position: 424113-422980 (Counterclockwise)

Preceding gene: 46445941

Following gene: 46445936

Centisome position: 17.57

GC content: 32.54

Gene sequence:

>1134_bases
TTGGATTTATATATTCGAAATCATTTAAGTTTTTGTTCACTTGAATTTTTAGACTTTAGCGAGTTCATTATGTATCGACT
ATTAAAAAATAGAACTAAAAAAACTGGCCTCTCCCCCGGATCTTTAATTCCCATAGGAGAAAAACCGCCCCACGAAATTA
AACTTTCCATCATTGAATATTCTGAATCAGAGTTTATTGAAAAAGAAAACGTATCTATAGAGGAATGTTTAGATCATCTT
ACAACTCCTAATATGACTTGGATTCAAGTGTTTGGCGTTTATGATCCTGCCAGCATTGCGTCGATTGGCAAACGTTTTGA
TTTACACGCACTTATCCAAGAAGATATTCTTAATACTTCTCAACGCCCAAAACTTGATATCTACCAAGACCAAGTTTTCA
TTGTTGCAAGATTTTTAAAATATAATCAACGAGATCATCAAATCCAAGACGAGCAAGTCAGTCTTATTTTTGGACAAAAT
TTACTCATTTCTTTTTTAGAACAAGATAAAGATGTTTTTACTTCTGTTAAAGAAAGACTTCGACAAGGTAACATTCGCAT
ACGCAAACAAAAGGCAGATTATTTGGCTTATGCTTTGTTAGATACTATTGTGGACCATTATTTCATCGTTTTAGAAAAAA
TTGATACCAATTTAGATCATTTAGAAGAAGAACTTGTCCGTTCTCCAAAACCTGGTACTTTACAAAGCATTCAGCGAGCT
AAACAAGAAATAGCTGTTTTGAAAAGATCTATTTGGCCTATGCGGGAGGTAGTTAATCGTTTTCAACGTATTGAACCTCC
GTTAGTCAATGCGCATACACAAATTTTCTTAAAAGATGTCTATGATCATATTATTCAAAACAATGATATCATTGAAGGGT
TTCGTGATGTAGTCTCAGGAATGTTAGATATTTATTTGTCTAACATCAATATTCGCTCAAATGAGATCATGAAAGTTTTG
ACAATTGTTTCCACAATTTTTGTTCCTTTAACGTTTATTTCAAGCATCTATGGAATGAATTTTGATAGCATGCCAGAATT
ACATTATCCATTTGGATATCCGTTGATTATGTTGTTCATGCTAACTTTGAGCTTATTGATGTTGCATTACTTCCGACAAA
AAAAATGGATTTAA

Upstream 100 bases:

>100_bases
ATTAAATGCGTTATCTCTAAAATAAAAGCTACATTTGTTGTCATCCATCAATTTAGTGAATGTTTGATCATCCATTAAAG
ATAAGCTAATCATCTAGATT

Downstream 100 bases:

>100_bases
TCATAAACAGTTGTACGACAAAAAGTTAAAGCATAAAGAGAACCAGGAAAACCTTCACTTAAAGCCTCCGCACATTTATG
AAGAGTTGTTCCTGTTGTCA

Product: putative divalent cation transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MDLYIRNHLSFCSLEFLDFSEFIMYRLLKNRTKKTGLSPGSLIPIGEKPPHEIKLSIIEYSESEFIEKENVSIEECLDHL
TTPNMTWIQVFGVYDPASIASIGKRFDLHALIQEDILNTSQRPKLDIYQDQVFIVARFLKYNQRDHQIQDEQVSLIFGQN
LLISFLEQDKDVFTSVKERLRQGNIRIRKQKADYLAYALLDTIVDHYFIVLEKIDTNLDHLEEELVRSPKPGTLQSIQRA
KQEIAVLKRSIWPMREVVNRFQRIEPPLVNAHTQIFLKDVYDHIIQNNDIIEGFRDVVSGMLDIYLSNINIRSNEIMKVL
TIVSTIFVPLTFISSIYGMNFDSMPELHYPFGYPLIMLFMLTLSLLMLHYFRQKKWI

Sequences:

>Translated_377_residues
MDLYIRNHLSFCSLEFLDFSEFIMYRLLKNRTKKTGLSPGSLIPIGEKPPHEIKLSIIEYSESEFIEKENVSIEECLDHL
TTPNMTWIQVFGVYDPASIASIGKRFDLHALIQEDILNTSQRPKLDIYQDQVFIVARFLKYNQRDHQIQDEQVSLIFGQN
LLISFLEQDKDVFTSVKERLRQGNIRIRKQKADYLAYALLDTIVDHYFIVLEKIDTNLDHLEEELVRSPKPGTLQSIQRA
KQEIAVLKRSIWPMREVVNRFQRIEPPLVNAHTQIFLKDVYDHIIQNNDIIEGFRDVVSGMLDIYLSNINIRSNEIMKVL
TIVSTIFVPLTFISSIYGMNFDSMPELHYPFGYPLIMLFMLTLSLLMLHYFRQKKWI
>Mature_377_residues
MDLYIRNHLSFCSLEFLDFSEFIMYRLLKNRTKKTGLSPGSLIPIGEKPPHEIKLSIIEYSESEFIEKENVSIEECLDHL
TTPNMTWIQVFGVYDPASIASIGKRFDLHALIQEDILNTSQRPKLDIYQDQVFIVARFLKYNQRDHQIQDEQVSLIFGQN
LLISFLEQDKDVFTSVKERLRQGNIRIRKQKADYLAYALLDTIVDHYFIVLEKIDTNLDHLEEELVRSPKPGTLQSIQRA
KQEIAVLKRSIWPMREVVNRFQRIEPPLVNAHTQIFLKDVYDHIIQNNDIIEGFRDVVSGMLDIYLSNINIRSNEIMKVL
TIVSTIFVPLTFISSIYGMNFDSMPELHYPFGYPLIMLFMLTLSLLMLHYFRQKKWI

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=236, Percent_Identity=27.9661016949153, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 44270; Mature: 44270

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYIRNHLSFCSLEFLDFSEFIMYRLLKNRTKKTGLSPGSLIPIGEKPPHEIKLSIIEY
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEEC
SESEFIEKENVSIEECLDHLTTPNMTWIQVFGVYDPASIASIGKRFDLHALIQEDILNTS
CHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
QRPKLDIYQDQVFIVARFLKYNQRDHQIQDEQVSLIFGQNLLISFLEQDKDVFTSVKERL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQGNIRIRKQKADYLAYALLDTIVDHYFIVLEKIDTNLDHLEEELVRSPKPGTLQSIQRA
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHH
KQEIAVLKRSIWPMREVVNRFQRIEPPLVNAHTQIFLKDVYDHIIQNNDIIEGFRDVVSG
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MLDIYLSNINIRSNEIMKVLTIVSTIFVPLTFISSIYGMNFDSMPELHYPFGYPLIMLFM
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LTLSLLMLHYFRQKKWI
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLYIRNHLSFCSLEFLDFSEFIMYRLLKNRTKKTGLSPGSLIPIGEKPPHEIKLSIIEY
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEEC
SESEFIEKENVSIEECLDHLTTPNMTWIQVFGVYDPASIASIGKRFDLHALIQEDILNTS
CHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
QRPKLDIYQDQVFIVARFLKYNQRDHQIQDEQVSLIFGQNLLISFLEQDKDVFTSVKERL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQGNIRIRKQKADYLAYALLDTIVDHYFIVLEKIDTNLDHLEEELVRSPKPGTLQSIQRA
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHH
KQEIAVLKRSIWPMREVVNRFQRIEPPLVNAHTQIFLKDVYDHIIQNNDIIEGFRDVVSG
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MLDIYLSNINIRSNEIMKVLTIVSTIFVPLTFISSIYGMNFDSMPELHYPFGYPLIMLFM
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LTLSLLMLHYFRQKKWI
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]