Click here to switch to the map view.

The map label for this gene is accD

Identifier: 46445903

GI number: 46445903

Start: 380973

End: 381890

Strand: Reverse

Name: accD

Synonym: pc0269

Alternate gene names: 46445903

Gene position: 381890-380973 (Counterclockwise)

Preceding gene: 46445904

Following gene: 46445902

Centisome position: 15.82

GC content: 37.91

Gene sequence:

>918_bases
ATGGGATTATTCTCTCGGGACAAGCCAAAAATTAAAATCCAAACCACCAAAAAGGATGGGTTTAGTGGATGGTTAAAATG
TACGCATTGCAATGAGCTAATCCACGCTAATGAATTAGAACAAAATAGCAACTGCTGCCCAAAATGTGATTATCACTATC
GTCTTTCAACTGAAGATCGTATTAAAAGTTTAAGTAATCCTAATACTTTTAAACCGTTATTTCAAAACTTACAACCTGTT
GACACTCTTAATTTTGTTGATACAGAACCCTATCCCAAAAGACTTGCAAATGCTCAGGAAAAATCGACTAGCAATGAAGC
TGTTGTTGTCGGTACGTGTATGATAAATAAACATAAAATTGCTCTAGGAGTCTTAGATTTCAGCTTTATGGGCGGCTCCA
TGGGATCTGTTGTAGGTGAACGGCTCACTCGTCTAATTGAACATGCTTTAAAAGAAAAACTTCCTTTAATTATTGTTTCG
ACCTCTGGCGGAGCTCGTATGCAAGAGTCGATTCTATCTCTTATGCAAATGGCCAAAACCTCAGGAGCACTTGCCAAGTT
ACATGAAGCGCGTATCCCCTATATTTCTGTTTTAACGAATCCAACAACTGGGGGCGTGACAGCCTCTTTTGCTTCTTTAG
GTGATATTATTGTTGCAGAACCGAATGCTTTGATTTGTTTCGCAGGTCCACGAGTTATTGAGCAAACTATCGGTCAACGA
CTCCCCCCAGGAGCCCAAAAATCAGAATTTTTACTTGAACATGGAATGATTGACTGTATCGTCAAACGGCCTGAACTCAA
ACAAAAATTGGCCGAACTTATTGACTTTTTAAAAGGAAATTTTTCTGAAGAAAATGAGCCTTCCCCCCCTCCTAAAAATT
TAATTAAAAAAACTTCTCCTTTAAAAGATAAAAATTAA

Upstream 100 bases:

>100_bases
ATACAAGATAGTTTATTAAGATAATTGAAATCATATATATATCTACCCAAATTTTCAATAAATACTATATTTCTTATAAA
AATTAATTGAGATACCAACG

Downstream 100 bases:

>100_bases
GTATTTTCATGACCCAATCTTATTCAAATACGTTGACTATTCCTACTCTAATTGAAAATGAAGAGCTACTTCCCTTCTAT
ATGACTCCCGAAGCAGCAGG

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MGLFSRDKPKIKIQTTKKDGFSGWLKCTHCNELIHANELEQNSNCCPKCDYHYRLSTEDRIKSLSNPNTFKPLFQNLQPV
DTLNFVDTEPYPKRLANAQEKSTSNEAVVVGTCMINKHKIALGVLDFSFMGGSMGSVVGERLTRLIEHALKEKLPLIIVS
TSGGARMQESILSLMQMAKTSGALAKLHEARIPYISVLTNPTTGGVTASFASLGDIIVAEPNALICFAGPRVIEQTIGQR
LPPGAQKSEFLLEHGMIDCIVKRPELKQKLAELIDFLKGNFSEENEPSPPPKNLIKKTSPLKDKN

Sequences:

>Translated_305_residues
MGLFSRDKPKIKIQTTKKDGFSGWLKCTHCNELIHANELEQNSNCCPKCDYHYRLSTEDRIKSLSNPNTFKPLFQNLQPV
DTLNFVDTEPYPKRLANAQEKSTSNEAVVVGTCMINKHKIALGVLDFSFMGGSMGSVVGERLTRLIEHALKEKLPLIIVS
TSGGARMQESILSLMQMAKTSGALAKLHEARIPYISVLTNPTTGGVTASFASLGDIIVAEPNALICFAGPRVIEQTIGQR
LPPGAQKSEFLLEHGMIDCIVKRPELKQKLAELIDFLKGNFSEENEPSPPPKNLIKKTSPLKDKN
>Mature_304_residues
GLFSRDKPKIKIQTTKKDGFSGWLKCTHCNELIHANELEQNSNCCPKCDYHYRLSTEDRIKSLSNPNTFKPLFQNLQPVD
TLNFVDTEPYPKRLANAQEKSTSNEAVVVGTCMINKHKIALGVLDFSFMGGSMGSVVGERLTRLIEHALKEKLPLIIVST
SGGARMQESILSLMQMAKTSGALAKLHEARIPYISVLTNPTTGGVTASFASLGDIIVAEPNALICFAGPRVIEQTIGQRL
PPGAQKSEFLLEHGMIDCIVKRPELKQKLAELIDFLKGNFSEENEPSPPPKNLIKKTSPLKDKN

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=269, Percent_Identity=51.3011152416357, Blast_Score=286, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_PARUW (Q6MEK6)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007268.1
- ProteinModelPortal:   Q6MEK6
- SMR:   Q6MEK6
- STRING:   Q6MEK6
- GeneID:   2781314
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0269
- NMPDR:   fig|264201.1.peg.269
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- PhylomeDB:   Q6MEK6
- ProtClustDB:   PRK05654
- BioCyc:   CPRO264201:PC0269-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 33647; Mature: 33516

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFSRDKPKIKIQTTKKDGFSGWLKCTHCNELIHANELEQNSNCCPKCDYHYRLSTEDR
CCCCCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHH
IKSLSNPNTFKPLFQNLQPVDTLNFVDTEPYPKRLANAQEKSTSNEAVVVGTCMINKHKI
HHHCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCHHHHCCCCCEEEEEEEEECCCEE
ALGVLDFSFMGGSMGSVVGERLTRLIEHALKEKLPLIIVSTSGGARMQESILSLMQMAKT
EEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHH
SGALAKLHEARIPYISVLTNPTTGGVTASFASLGDIIVAEPNALICFAGPRVIEQTIGQR
HHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCEEEECCCEEEEECCHHHHHHHHHHC
LPPGAQKSEFLLEHGMIDCIVKRPELKQKLAELIDFLKGNFSEENEPSPPPKNLIKKTSP
CCCCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCC
LKDKN
CCCCC
>Mature Secondary Structure 
GLFSRDKPKIKIQTTKKDGFSGWLKCTHCNELIHANELEQNSNCCPKCDYHYRLSTEDR
CCCCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHH
IKSLSNPNTFKPLFQNLQPVDTLNFVDTEPYPKRLANAQEKSTSNEAVVVGTCMINKHKI
HHHCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCHHHHCCCCCEEEEEEEEECCCEE
ALGVLDFSFMGGSMGSVVGERLTRLIEHALKEKLPLIIVSTSGGARMQESILSLMQMAKT
EEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHH
SGALAKLHEARIPYISVLTNPTTGGVTASFASLGDIIVAEPNALICFAGPRVIEQTIGQR
HHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCEEEECCCEEEEECCHHHHHHHHHHC
LPPGAQKSEFLLEHGMIDCIVKRPELKQKLAELIDFLKGNFSEENEPSPPPKNLIKKTSP
CCCCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCC
LKDKN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA