Click here to switch to the map view.

The map label for this gene is npr [H]

Identifier: 46445829

GI number: 46445829

Start: 290379

End: 291191

Strand: Reverse

Name: npr [H]

Synonym: pc0195

Alternate gene names: 46445829

Gene position: 291191-290379 (Counterclockwise)

Preceding gene: 46445830

Following gene: 46445828

Centisome position: 12.06

GC content: 35.06

Gene sequence:

>813_bases
ATGGCAGAATTATCGCACGCTTTTAATAGTCCCTCACCATATCAACCAACACAAGTTCTTTCATATACTACAGAAGAACT
TTTGCAAAAAGGTTACCTAGCTATTCCCTGCAGTACCCAAGAAGAAGCAAAACTTTGTTTAAAAATCAATGCAGTAGTAG
AAACAATAAAAGAATTTTATTGGATGAATTTTCAACTAATAGGTGTAAATGTGGATAAAGAGGGAGCTATTCCACCGTTT
TTTATTCATTATCCTAAAGAAAATGCCTATTATGCTCCTAAGCTGAAACATTTCGCTTTTGATAACAAATTTGCTTCTTG
CCTAGATATTGTGTGTCATGAAATGACACACGCCGTGATAGCGTATCATAATCCATTACAATATAAAGGAGAATCAGGAG
CGTTAGATGAAGCAATTGCGGATGTTGCTGCTATAGCGTTCAAACAATATGAGAGTACGAGTCAAAATGATTGGCAAATT
GGTAATTTGCGTAACTTAAGCAAAATCCCTGAAAAATTTAAGTCTTCTCCTACATATAGCCTCGGCAATGATTTCGGCTA
TGTGCATGATAATAGCTTGATTATCAGCCATACATTTTATCTTGCTTCAAAAAATCTGTCTCATGATTCAACTCATTGTA
AATTACTCTTTAACATTTGGTTTAAGTCGATGTTAGCTCTTGGAGATAAAACTTTTAAAGGATTTAGAGCTAAGACAATC
AAAGTTGCTAATGAGAATATTCATACAGTCGGTAGGATTGTTATTAACGCTATCTCCGATGCTTGGGAACAAACCTCACC
CCTTTTTCCGTAA

Upstream 100 bases:

>100_bases
TACGCCCAATTAAATATAAAAACTTCAAGCTATTCTGTTCGTGCTGAAATGACTAAATAAATTATTTTTTATCAAATAAT
TCAAAAACAAAGGAATAAAA

Downstream 100 bases:

>100_bases
AATGTTAACAAATTTAGTTGGTTGACTTGGGCCCTGCTAACATTCTAGACAAATGACATAAAACGTATTAAAAAATGGGA
AATTAAAAAAGCTACCAACC

Product: putative metalloendopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MAELSHAFNSPSPYQPTQVLSYTTEELLQKGYLAIPCSTQEEAKLCLKINAVVETIKEFYWMNFQLIGVNVDKEGAIPPF
FIHYPKENAYYAPKLKHFAFDNKFASCLDIVCHEMTHAVIAYHNPLQYKGESGALDEAIADVAAIAFKQYESTSQNDWQI
GNLRNLSKIPEKFKSSPTYSLGNDFGYVHDNSLIISHTFYLASKNLSHDSTHCKLLFNIWFKSMLALGDKTFKGFRAKTI
KVANENIHTVGRIVINAISDAWEQTSPLFP

Sequences:

>Translated_270_residues
MAELSHAFNSPSPYQPTQVLSYTTEELLQKGYLAIPCSTQEEAKLCLKINAVVETIKEFYWMNFQLIGVNVDKEGAIPPF
FIHYPKENAYYAPKLKHFAFDNKFASCLDIVCHEMTHAVIAYHNPLQYKGESGALDEAIADVAAIAFKQYESTSQNDWQI
GNLRNLSKIPEKFKSSPTYSLGNDFGYVHDNSLIISHTFYLASKNLSHDSTHCKLLFNIWFKSMLALGDKTFKGFRAKTI
KVANENIHTVGRIVINAISDAWEQTSPLFP
>Mature_269_residues
AELSHAFNSPSPYQPTQVLSYTTEELLQKGYLAIPCSTQEEAKLCLKINAVVETIKEFYWMNFQLIGVNVDKEGAIPPFF
IHYPKENAYYAPKLKHFAFDNKFASCLDIVCHEMTHAVIAYHNPLQYKGESGALDEAIADVAAIAFKQYESTSQNDWQIG
NLRNLSKIPEKFKSSPTYSLGNDFGYVHDNSLIISHTFYLASKNLSHDSTHCKLLFNIWFKSMLALGDKTFKGFRAKTIK
VANENIHTVGRIVINAISDAWEQTSPLFP

Specific function: Unknown

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013856
- InterPro:   IPR001570 [H]

Pfam domain/function: PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: NA

Molecular weight: Translated: 30544; Mature: 30413

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELSHAFNSPSPYQPTQVLSYTTEELLQKGYLAIPCSTQEEAKLCLKINAVVETIKEFY
CCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
WMNFQLIGVNVDKEGAIPPFFIHYPKENAYYAPKLKHFAFDNKFASCLDIVCHEMTHAVI
HCCEEEEEEEECCCCCCCCEEEECCCCCCEECCCHHHHHHCCHHHHHHHHHHHHHHHHHH
AYHNPLQYKGESGALDEAIADVAAIAFKQYESTSQNDWQIGNLRNLSKIPEKFKSSPTYS
EECCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCCCCCC
LGNDFGYVHDNSLIISHTFYLASKNLSHDSTHCKLLFNIWFKSMLALGDKTFKGFRAKTI
CCCCCCEEECCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCEEEE
KVANENIHTVGRIVINAISDAWEQTSPLFP
EECCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AELSHAFNSPSPYQPTQVLSYTTEELLQKGYLAIPCSTQEEAKLCLKINAVVETIKEFY
CCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
WMNFQLIGVNVDKEGAIPPFFIHYPKENAYYAPKLKHFAFDNKFASCLDIVCHEMTHAVI
HCCEEEEEEEECCCCCCCCEEEECCCCCCEECCCHHHHHHCCHHHHHHHHHHHHHHHHHH
AYHNPLQYKGESGALDEAIADVAAIAFKQYESTSQNDWQIGNLRNLSKIPEKFKSSPTYS
EECCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCCCCCC
LGNDFGYVHDNSLIISHTFYLASKNLSHDSTHCKLLFNIWFKSMLALGDKTFKGFRAKTI
CCCCCCEEECCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCEEEE
KVANENIHTVGRIVINAISDAWEQTSPLFP
EECCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917878 [H]