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The map label for this gene is aroB

Identifier: 46445707

GI number: 46445707

Start: 132397

End: 133455

Strand: Reverse

Name: aroB

Synonym: pc0073

Alternate gene names: 46445707

Gene position: 133455-132397 (Counterclockwise)

Preceding gene: 46445708

Following gene: 46445706

Centisome position: 5.53

GC content: 33.9

Gene sequence:

>1059_bases
ATGTTAAACTCATCAAACTATGTCATTCAAAGCCATTGTTTAGATGATTTAAAATACTATTTAGAGTCTTTATCTTACTC
AAAAGTTGTCATCATAACTCATCCTCAGTTATGGGTAATGTATGAGCAGAAAATAACGGAGCAGTTGTTTAAGCTCAGCT
GGAATTTTTCCGTTTTACTGATCCCTGAAGGTGAAACGAGTAAAAGCTTAAAACAAACAACAAGATGCTGGCGACATTTT
ATCAAACACCAACTAGATCGATATTCTCTTGTGGTCGCTTTAGGAGGCGGTGTTATCTGTGATTTAGCGGGATTTGTAGC
CTCTTGCTATATGAGAGGAATCGATACGATTTATCTTCCAACTACCCTTCTTGCCATGGTTGATGCTAGTATCGGTGGAA
AAACAGGAATTAACACAAGTAAATCTAAAAATATTATAGGATCATTCCATCTACCTAAAAAAATTTTAATAGATCCTTTT
ACTTTAAAAACACTTTCAAAAAAGCATTATCAAGCAGGTTTTGCAGAAATTATTAAATATGGAATGATTGCCTCACCCTC
ACTTTTTGAATTTCTTGAAAATTCTTGGTCCCTTATAGAACAAAGAGATGAAGGATTACTCGAGATTATCATTCAACAAT
CATGTGCAATTAAAAAAAAATATGTTGAAGCTGATTTTAAAGATTTGGGAATAAGAGCCCAGCTGAACTACGGCCATACA
TTTGGTCATGTAATTGAAATGATGAGCCGTTATCAATATTTACATGGGGAAGCAGTTTCTATTGGAATGAGCTGCGCTGC
TTATTTAAGTTGTCAAATGGGTTTAACAACGCAAGAAACTATGCAAAGGCAAGATGCACTTTGTCAACAAGCTCAATTAC
CTATTCATTTACCTCATTTTCCGCTTACACGTTTCACTTATTTAATGGCAAAAGATAAAAAGGGACGAAATGGTTCTATT
AATCTCATTCTGCCTGAAAAAGTTGGTAAAGTGACACAAATTTTTGATGTAGACCCTCATTTAATAAAAAATACTCTGTC
AACAAAAATGACAAAATAA

Upstream 100 bases:

>100_bases
AATTTTGTAGAATTATCAATCTACATTCAAATTCTTAGCAAAAAAAAATTTAACGAAGTTTTTGATTTTCAATTAAATAA
ATTCGAAACGTAAGGTTAAT

Downstream 100 bases:

>100_bases
TAGAATTTTTTCGAAATTTTTAAAGAAAAAAAGAAAGAACTAGTCTTAACACATAAAGATTTTTCAATTTCTATTTTCAA
AACAATCTAATTTTTCATTT

Product: putative 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MLNSSNYVIQSHCLDDLKYYLESLSYSKVVIITHPQLWVMYEQKITEQLFKLSWNFSVLLIPEGETSKSLKQTTRCWRHF
IKHQLDRYSLVVALGGGVICDLAGFVASCYMRGIDTIYLPTTLLAMVDASIGGKTGINTSKSKNIIGSFHLPKKILIDPF
TLKTLSKKHYQAGFAEIIKYGMIASPSLFEFLENSWSLIEQRDEGLLEIIIQQSCAIKKKYVEADFKDLGIRAQLNYGHT
FGHVIEMMSRYQYLHGEAVSIGMSCAAYLSCQMGLTTQETMQRQDALCQQAQLPIHLPHFPLTRFTYLMAKDKKGRNGSI
NLILPEKVGKVTQIFDVDPHLIKNTLSTKMTK

Sequences:

>Translated_352_residues
MLNSSNYVIQSHCLDDLKYYLESLSYSKVVIITHPQLWVMYEQKITEQLFKLSWNFSVLLIPEGETSKSLKQTTRCWRHF
IKHQLDRYSLVVALGGGVICDLAGFVASCYMRGIDTIYLPTTLLAMVDASIGGKTGINTSKSKNIIGSFHLPKKILIDPF
TLKTLSKKHYQAGFAEIIKYGMIASPSLFEFLENSWSLIEQRDEGLLEIIIQQSCAIKKKYVEADFKDLGIRAQLNYGHT
FGHVIEMMSRYQYLHGEAVSIGMSCAAYLSCQMGLTTQETMQRQDALCQQAQLPIHLPHFPLTRFTYLMAKDKKGRNGSI
NLILPEKVGKVTQIFDVDPHLIKNTLSTKMTK
>Mature_352_residues
MLNSSNYVIQSHCLDDLKYYLESLSYSKVVIITHPQLWVMYEQKITEQLFKLSWNFSVLLIPEGETSKSLKQTTRCWRHF
IKHQLDRYSLVVALGGGVICDLAGFVASCYMRGIDTIYLPTTLLAMVDASIGGKTGINTSKSKNIIGSFHLPKKILIDPF
TLKTLSKKHYQAGFAEIIKYGMIASPSLFEFLENSWSLIEQRDEGLLEIIIQQSCAIKKKYVEADFKDLGIRAQLNYGHT
FGHVIEMMSRYQYLHGEAVSIGMSCAAYLSCQMGLTTQETMQRQDALCQQAQLPIHLPHFPLTRFTYLMAKDKKGRNGSI
NLILPEKVGKVTQIFDVDPHLIKNTLSTKMTK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=342, Percent_Identity=36.5497076023392, Blast_Score=202, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6320332, Length=309, Percent_Identity=33.9805825242718, Blast_Score=160, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_PARUW (Q6MF52)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007072.1
- ProteinModelPortal:   Q6MF52
- SMR:   Q6MF52
- STRING:   Q6MF52
- GeneID:   2779772
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0073
- NMPDR:   fig|264201.1.peg.73
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- PhylomeDB:   Q6MF52
- BioCyc:   CPRO264201:PC0073-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39939; Mature: 39939

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSSNYVIQSHCLDDLKYYLESLSYSKVVIITHPQLWVMYEQKITEQLFKLSWNFSVLL
CCCCCCCEEHHHHHHHHHHHHHHCCCCEEEEEECCCEEEHHHHHHHHHHHHHCCCEEEEE
IPEGETSKSLKQTTRCWRHFIKHQLDRYSLVVALGGGVICDLAGFVASCYMRGIDTIYLP
EECCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCEEHHH
TTLLAMVDASIGGKTGINTSKSKNIIGSFHLPKKILIDPFTLKTLSKKHYQAGFAEIIKY
HHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GMIASPSLFEFLENSWSLIEQRDEGLLEIIIQQSCAIKKKYVEADFKDLGIRAQLNYGHT
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECCCCH
FGHVIEMMSRYQYLHGEAVSIGMSCAAYLSCQMGLTTQETMQRQDALCQQAQLPIHLPHF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCC
PLTRFTYLMAKDKKGRNGSINLILPEKVGKVTQIFDVDPHLIKNTLSTKMTK
CHHHHHHHHEECCCCCCCCEEEEECHHCCCCCEEECCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLNSSNYVIQSHCLDDLKYYLESLSYSKVVIITHPQLWVMYEQKITEQLFKLSWNFSVLL
CCCCCCCEEHHHHHHHHHHHHHHCCCCEEEEEECCCEEEHHHHHHHHHHHHHCCCEEEEE
IPEGETSKSLKQTTRCWRHFIKHQLDRYSLVVALGGGVICDLAGFVASCYMRGIDTIYLP
EECCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCEEHHH
TTLLAMVDASIGGKTGINTSKSKNIIGSFHLPKKILIDPFTLKTLSKKHYQAGFAEIIKY
HHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GMIASPSLFEFLENSWSLIEQRDEGLLEIIIQQSCAIKKKYVEADFKDLGIRAQLNYGHT
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECCCCH
FGHVIEMMSRYQYLHGEAVSIGMSCAAYLSCQMGLTTQETMQRQDALCQQAQLPIHLPHF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCC
PLTRFTYLMAKDKKGRNGSINLILPEKVGKVTQIFDVDPHLIKNTLSTKMTK
CHHHHHHHHEECCCCCCCCEEEEECHHCCCCCEEECCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA