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The map label for this gene is recD [H]

Identifier: 46445644

GI number: 46445644

Start: 18855

End: 20723

Strand: Direct

Name: recD [H]

Synonym: pc0010

Alternate gene names: 46445644

Gene position: 18855-20723 (Clockwise)

Preceding gene: 46445643

Following gene: 46445645

Centisome position: 0.78

GC content: 34.67

Gene sequence:

>1869_bases
GTGAAGGTAATGGAAAGAGGATTCGCAAAGCAAAATTTTTTAGAATCATATAAGTTAGCTCCTTGGTTGGGCACAAAAAG
AGCTCAAGACTTACCGAATTGGCCCCTCGTTAATCAGTTATTAAGTAAAAATCAACTTTCTTATTTAAACTATCTTTTAA
CTTTAGAAATTATTAAAGATCAATGGATCAATCAAAACCTTGTGTTGTTTATTTGCCATCTTTTGATGGCTGCTCAAGAG
GGGCATTTATGCGTGGAAATCAGGAATCAGACTTTATTTCCTACGGTAAAACAACTTTGGACGAATGAAGCGGCAGCACC
GTTATCTAATGAAGAGTTAGAGAATTTAACCCATTCAATTTTGCAGGGATCACAAAATATTCCGGTTAATTTTGTGACAG
CTATGGATAGCCTTGAAAATTCTGTTTATCCGAATACTCCCATATGTATGCATAAAGGCAATTTTTATTTGCAAAAACAT
TGGGTTTTGGAAACAGTTTTTCTAAAAAATTTAAACAAACATTTACAAACATCCCCAACGCTTGAATTAAATCGAGTTGT
TCTTGAACAACACCTTAATGAATGTGTGTTGAAAAAAAAATTGTTATTGGAACAAGCTCAAGCAATTTTAACAGGATGCT
TATCGTCTCTTTCACTTATTACTGGTGGACCTGGAACCGGAAAAACTTTTACGGCTGGCCGTTTTATTCAAATTTATTGG
GATAGTTTAAAAGAATGTCAGAAAAAAAACTGCCAAATTGCTTTAGCAGCACCGACGGGTAAAGCTGCTGCAAATTTACA
AAAAAGTTTGAGTTTAGTCACCGCGCAGTTAAAAGATTTTCCTCCTTTAAAAGCAAAAACTTTGCATCAATTATTGGGAA
TTAATAATCGCTCAAGAAATGAATCTGGTATAAGATTAGCAGCGGATTTGATTATTGTAGATGAAAGTTCGATGATCGAT
GTCAAAATGATGGCTTATTTATTTGAAGCTTTAAAAAAAGGCTCGCGACTGATTTTACTCGGTGATCAGCATCAATTACC
TTCTGTGGAAGCAGGAAGTTTATTTGCTGATTTGACGAAATTAAAAACAAAAATTCCCTGTACAGAACTGAAAGTTTGTT
TACGCACAGAATTAAGCTCTATTGTTTCATTGGCGCATTATATTAATCAAGGAAAGGGTCAAGAAACGTTGAGCATGCTT
AACGAAACACAGATTGCTGGGATTTCTCGTTTAAATTTGTCTCCAGATAGAAGAGAAGCGCAAAAAGAATTTGTCCAGCA
CGTTATGAATCATTTTCCTTTATCTATAAAAGTTCACGATAATCAAAAAATATTAGAGCTTTTTAATACCATTCGTATTT
TATCACCTATGCGAAAAGGGTATTTTGGAGTAGATAGCATTAATCAGCTCATTTGGAATCATGTGAGCCAAATAAAACTA
TCACCAGGGTGGTTAGCAATTCCTATTATTATTGTCACGAATGATTACAAACAAAATTTGTTCAATGGCGAAACTGGTGT
GTTAATTCGAAAACTACCTTTAAAATCAATAACGAGCGAAGATTATGCTTTATTTCCTTCTAAAGATGAGGGAGAAAATA
TGCGTTGTTTACCCGCTTGTTTACTTCCTAAGTATGAATTAGCTTATTGCTTATCTGTCCATAAGAGTCAGGGCAGCGAA
TTCGAGAGAGTCATTTTAATGTTACCTGAAGGATCGGAATGCTTTGGTAGAGAAGTTTTTTATACTGGCGTTACGAGGGC
TCGTAAACATATTGAGGTGTGGGGAACCGATTTCACAATTGAAAAAACAATTTCTCAACAAAGTTTTCGCTTATCTGGGA
TTCAAACGCGTCTGGAAAAATTTATTTAA

Upstream 100 bases:

>100_bases
TTTACTTATTTTTAAGAGGAATTCAATCTAATAAACAATCAGGAATTTATTTTTGTGACGCGCAGGATCTAATAAAAATT
TTCTCGCCTAAAAATTACGA

Downstream 100 bases:

>100_bases
TTAAATTAAATTGATTAACCTCACCCACAATAATTTAAAAATACGAGAACAAAAAATTTGTGCTAAATAAAGAATTTATT
TCAAACAAGGGTTGTTAAAG

Product: putative exodeoxyribonuclease V alpha chain recD

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MKVMERGFAKQNFLESYKLAPWLGTKRAQDLPNWPLVNQLLSKNQLSYLNYLLTLEIIKDQWINQNLVLFICHLLMAAQE
GHLCVEIRNQTLFPTVKQLWTNEAAAPLSNEELENLTHSILQGSQNIPVNFVTAMDSLENSVYPNTPICMHKGNFYLQKH
WVLETVFLKNLNKHLQTSPTLELNRVVLEQHLNECVLKKKLLLEQAQAILTGCLSSLSLITGGPGTGKTFTAGRFIQIYW
DSLKECQKKNCQIALAAPTGKAAANLQKSLSLVTAQLKDFPPLKAKTLHQLLGINNRSRNESGIRLAADLIIVDESSMID
VKMMAYLFEALKKGSRLILLGDQHQLPSVEAGSLFADLTKLKTKIPCTELKVCLRTELSSIVSLAHYINQGKGQETLSML
NETQIAGISRLNLSPDRREAQKEFVQHVMNHFPLSIKVHDNQKILELFNTIRILSPMRKGYFGVDSINQLIWNHVSQIKL
SPGWLAIPIIIVTNDYKQNLFNGETGVLIRKLPLKSITSEDYALFPSKDEGENMRCLPACLLPKYELAYCLSVHKSQGSE
FERVILMLPEGSECFGREVFYTGVTRARKHIEVWGTDFTIEKTISQQSFRLSGIQTRLEKFI

Sequences:

>Translated_622_residues
MKVMERGFAKQNFLESYKLAPWLGTKRAQDLPNWPLVNQLLSKNQLSYLNYLLTLEIIKDQWINQNLVLFICHLLMAAQE
GHLCVEIRNQTLFPTVKQLWTNEAAAPLSNEELENLTHSILQGSQNIPVNFVTAMDSLENSVYPNTPICMHKGNFYLQKH
WVLETVFLKNLNKHLQTSPTLELNRVVLEQHLNECVLKKKLLLEQAQAILTGCLSSLSLITGGPGTGKTFTAGRFIQIYW
DSLKECQKKNCQIALAAPTGKAAANLQKSLSLVTAQLKDFPPLKAKTLHQLLGINNRSRNESGIRLAADLIIVDESSMID
VKMMAYLFEALKKGSRLILLGDQHQLPSVEAGSLFADLTKLKTKIPCTELKVCLRTELSSIVSLAHYINQGKGQETLSML
NETQIAGISRLNLSPDRREAQKEFVQHVMNHFPLSIKVHDNQKILELFNTIRILSPMRKGYFGVDSINQLIWNHVSQIKL
SPGWLAIPIIIVTNDYKQNLFNGETGVLIRKLPLKSITSEDYALFPSKDEGENMRCLPACLLPKYELAYCLSVHKSQGSE
FERVILMLPEGSECFGREVFYTGVTRARKHIEVWGTDFTIEKTISQQSFRLSGIQTRLEKFI
>Mature_622_residues
MKVMERGFAKQNFLESYKLAPWLGTKRAQDLPNWPLVNQLLSKNQLSYLNYLLTLEIIKDQWINQNLVLFICHLLMAAQE
GHLCVEIRNQTLFPTVKQLWTNEAAAPLSNEELENLTHSILQGSQNIPVNFVTAMDSLENSVYPNTPICMHKGNFYLQKH
WVLETVFLKNLNKHLQTSPTLELNRVVLEQHLNECVLKKKLLLEQAQAILTGCLSSLSLITGGPGTGKTFTAGRFIQIYW
DSLKECQKKNCQIALAAPTGKAAANLQKSLSLVTAQLKDFPPLKAKTLHQLLGINNRSRNESGIRLAADLIIVDESSMID
VKMMAYLFEALKKGSRLILLGDQHQLPSVEAGSLFADLTKLKTKIPCTELKVCLRTELSSIVSLAHYINQGKGQETLSML
NETQIAGISRLNLSPDRREAQKEFVQHVMNHFPLSIKVHDNQKILELFNTIRILSPMRKGYFGVDSINQLIWNHVSQIKL
SPGWLAIPIIIVTNDYKQNLFNGETGVLIRKLPLKSITSEDYALFPSKDEGENMRCLPACLLPKYELAYCLSVHKSQGSE
FERVILMLPEGSECFGREVFYTGVTRARKHIEVWGTDFTIEKTISQQSFRLSGIQTRLEKFI

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=631, Percent_Identity=28.2091917591125, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 70386; Mature: 70386

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVMERGFAKQNFLESYKLAPWLGTKRAQDLPNWPLVNQLLSKNQLSYLNYLLTLEIIKD
CCCHHHCCHHHHHHHHHCCCCCCCCCHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
QWINQNLVLFICHLLMAAQEGHLCVEIRNQTLFPTVKQLWTNEAAAPLSNEELENLTHSI
HHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LQGSQNIPVNFVTAMDSLENSVYPNTPICMHKGNFYLQKHWVLETVFLKNLNKHLQTSPT
HCCCCCCCEEHHHHHHHHHCCCCCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHCCCCC
LELNRVVLEQHLNECVLKKKLLLEQAQAILTGCLSSLSLITGGPGTGKTFTAGRFIQIYW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEHHH
DSLKECQKKNCQIALAAPTGKAAANLQKSLSLVTAQLKDFPPLKAKTLHQLLGINNRSRN
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
ESGIRLAADLIIVDESSMIDVKMMAYLFEALKKGSRLILLGDQHQLPSVEAGSLFADLTK
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHH
LKTKIPCTELKVCLRTELSSIVSLAHYINQGKGQETLSMLNETQIAGISRLNLSPDRREA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCCHHHHH
QKEFVQHVMNHFPLSIKVHDNQKILELFNTIRILSPMRKGYFGVDSINQLIWNHVSQIKL
HHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEE
SPGWLAIPIIIVTNDYKQNLFNGETGVLIRKLPLKSITSEDYALFPSKDEGENMRCLPAC
CCCEEEEEEEEEECCHHHHHCCCCCCEEEEECCCHHCCCCCEEECCCCCCCCCCEEEHHH
LLPKYELAYCLSVHKSQGSEFERVILMLPEGSECFGREVFYTGVTRARKHIEVWGTDFTI
HCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHCCHHHHHHHHHHHHEEEEECCCEEE
EKTISQQSFRLSGIQTRLEKFI
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVMERGFAKQNFLESYKLAPWLGTKRAQDLPNWPLVNQLLSKNQLSYLNYLLTLEIIKD
CCCHHHCCHHHHHHHHHCCCCCCCCCHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
QWINQNLVLFICHLLMAAQEGHLCVEIRNQTLFPTVKQLWTNEAAAPLSNEELENLTHSI
HHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LQGSQNIPVNFVTAMDSLENSVYPNTPICMHKGNFYLQKHWVLETVFLKNLNKHLQTSPT
HCCCCCCCEEHHHHHHHHHCCCCCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHCCCCC
LELNRVVLEQHLNECVLKKKLLLEQAQAILTGCLSSLSLITGGPGTGKTFTAGRFIQIYW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEHHH
DSLKECQKKNCQIALAAPTGKAAANLQKSLSLVTAQLKDFPPLKAKTLHQLLGINNRSRN
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
ESGIRLAADLIIVDESSMIDVKMMAYLFEALKKGSRLILLGDQHQLPSVEAGSLFADLTK
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHH
LKTKIPCTELKVCLRTELSSIVSLAHYINQGKGQETLSMLNETQIAGISRLNLSPDRREA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCCHHHHH
QKEFVQHVMNHFPLSIKVHDNQKILELFNTIRILSPMRKGYFGVDSINQLIWNHVSQIKL
HHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEE
SPGWLAIPIIIVTNDYKQNLFNGETGVLIRKLPLKSITSEDYALFPSKDEGENMRCLPAC
CCCEEEEEEEEEECCHHHHHCCCCCCEEEEECCCHHCCCCCEEECCCCCCCCCCEEEHHH
LLPKYELAYCLSVHKSQGSEFERVILMLPEGSECFGREVFYTGVTRARKHIEVWGTDFTI
HCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHCCHHHHHHHHHHHHEEEEECCCEEE
EKTISQQSFRLSGIQTRLEKFI
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]