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The map label for this gene is pkn1 [H]

Identifier: 45659053

GI number: 45659053

Start: 3966708

End: 3968021

Strand: Direct

Name: pkn1 [H]

Synonym: LIC13231

Alternate gene names: 45659053

Gene position: 3966708-3968021 (Clockwise)

Preceding gene: 45659052

Following gene: 45659055

Centisome position: 92.74

GC content: 38.51

Gene sequence:

>1314_bases
ATGACTTTCGATTTTAAACTCAAACGATTCTATTTTTTCCTTTTATTTGGATCGATTACTTTTCTATTCGCACAAACACA
AGATTCCTCTCTTAATACGAGAATGATCCCACTTTGGAAAGGAGAAGTAGAAGCGGTTTATAGCGGTAAAGGTAAGGTAA
AAATTCGAATCCGAAGAGGTTCTATATTTTACGGTAAGGAAGAAGAGGAAATCAAAGCCATCCTGGAAAAAAAATCTCAG
TATTCCGTCTTACAAAAAAATCCCGAAAAAGAAATCGGCTACTTTTCTATCCGCCAGATCTCAGTGGTCTATCAAAACAA
TTCAGGTGGAAAAAAAGCTTCCGAAGTTGAACTTTATGGTTCATTTTCTGCAATTCCAGGTGTCCCTGAAAGTTTACTCA
CAGCAGGAACTTTTATCCAAGACTATAAACAAGAAATCGCCTATATCGAACCGGGTGCTTTTTTCACCGAAGATAGAAGA
AGAACAAGACCTTCAAAACAACTTAGACATCCCAAAGACGGTAAGGAGATGGTTCTTGTCTCAGGAGGTTACGAACAAAA
CGGAGAACCGTTTTACGAATCGATGGGATTTTTTATTCACGGACAAGGAAACGATCCTTCTGAAGACAGTTATAATCCAT
TTTATTTTAAACCAGAGCGTGGTAATCTTCAAGACGTCTCTTCTTTTTATATAGATAAGTACGAAGTTACAAATCAAGAA
TATTCAAAATTCTTAAAGGAAACAAACACTTCTCCCCCACCTCATTGGAAAAGTGGAAACTTTCCTGCGGGAAAAGAACA
TCATCCAGTCAGCGGGATCACTTACAGAGAAGCGGAAACTTACGCACGTTGGTCCGGTAAAAGACTTCCTACAGAAATGG
AATGGGAAAAAGCGGCTCGCGGAACCGGAATGACTTGGAAAATTAATCGAGACGAATCCTATTCTTTTTTTCCAAGTCCT
TTGGAATATCCGTTCGGAAACGATTTTGATTCTACATTATGCAATACTATAGAAAGCAAACAAAACGATACAATTTCAGT
TTACGAACTTGCAAAAAAATCTGCAAGTCCTTACGGAGTCATCGGAATGTGCGGAAATATAGCAGAGTGGACAAGCTCGG
ATTATCTTCCCTATCCAGGACATTCTCTCAAAAGAAACACATTCGGAAAAATGCATAAAGTAATTAGAGGCGGCTCGTTT
TCCTCTACAAAAGAAGAAGCCACTACTTACTTTAGATCCTTTGGTGGAATTCCAAATTTAAAAACGGATCGCAGAGCCGG
CTTTAGACTTGTTTGGGATCTTCCTGGAAAATAA

Upstream 100 bases:

>100_bases
TAGATTTGTAATCTTCGGGAAATTTATTTTTTAATCCTGAAATTTATGCCGAAATGAATAATAGAAAAACCGTTCTTTAC
AAAACGGATTATTAAACATT

Downstream 100 bases:

>100_bases
AGAATATTCAATTTCTATAAACTACTCAGAAAACTATACAATAGAGTATTAAATATTTTGCATTCAAACAATGCTTTGCA
ATAAAAAATTATAGTATTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTFDFKLKRFYFFLLFGSITFLFAQTQDSSLNTRMIPLWKGEVEAVYSGKGKVKIRIRRGSIFYGKEEEEIKAILEKKSQ
YSVLQKNPEKEIGYFSIRQISVVYQNNSGGKKASEVELYGSFSAIPGVPESLLTAGTFIQDYKQEIAYIEPGAFFTEDRR
RTRPSKQLRHPKDGKEMVLVSGGYEQNGEPFYESMGFFIHGQGNDPSEDSYNPFYFKPERGNLQDVSSFYIDKYEVTNQE
YSKFLKETNTSPPPHWKSGNFPAGKEHHPVSGITYREAETYARWSGKRLPTEMEWEKAARGTGMTWKINRDESYSFFPSP
LEYPFGNDFDSTLCNTIESKQNDTISVYELAKKSASPYGVIGMCGNIAEWTSSDYLPYPGHSLKRNTFGKMHKVIRGGSF
SSTKEEATTYFRSFGGIPNLKTDRRAGFRLVWDLPGK

Sequences:

>Translated_437_residues
MTFDFKLKRFYFFLLFGSITFLFAQTQDSSLNTRMIPLWKGEVEAVYSGKGKVKIRIRRGSIFYGKEEEEIKAILEKKSQ
YSVLQKNPEKEIGYFSIRQISVVYQNNSGGKKASEVELYGSFSAIPGVPESLLTAGTFIQDYKQEIAYIEPGAFFTEDRR
RTRPSKQLRHPKDGKEMVLVSGGYEQNGEPFYESMGFFIHGQGNDPSEDSYNPFYFKPERGNLQDVSSFYIDKYEVTNQE
YSKFLKETNTSPPPHWKSGNFPAGKEHHPVSGITYREAETYARWSGKRLPTEMEWEKAARGTGMTWKINRDESYSFFPSP
LEYPFGNDFDSTLCNTIESKQNDTISVYELAKKSASPYGVIGMCGNIAEWTSSDYLPYPGHSLKRNTFGKMHKVIRGGSF
SSTKEEATTYFRSFGGIPNLKTDRRAGFRLVWDLPGK
>Mature_436_residues
TFDFKLKRFYFFLLFGSITFLFAQTQDSSLNTRMIPLWKGEVEAVYSGKGKVKIRIRRGSIFYGKEEEEIKAILEKKSQY
SVLQKNPEKEIGYFSIRQISVVYQNNSGGKKASEVELYGSFSAIPGVPESLLTAGTFIQDYKQEIAYIEPGAFFTEDRRR
TRPSKQLRHPKDGKEMVLVSGGYEQNGEPFYESMGFFIHGQGNDPSEDSYNPFYFKPERGNLQDVSSFYIDKYEVTNQEY
SKFLKETNTSPPPHWKSGNFPAGKEHHPVSGITYREAETYARWSGKRLPTEMEWEKAARGTGMTWKINRDESYSFFPSPL
EYPFGNDFDSTLCNTIESKQNDTISVYELAKKSASPYGVIGMCGNIAEWTSSDYLPYPGHSLKRNTFGKMHKVIRGGSFS
STKEEATTYFRSFGGIPNLKTDRRAGFRLVWDLPGK

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 50000; Mature: 49868

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFDFKLKRFYFFLLFGSITFLFAQTQDSSLNTRMIPLWKGEVEAVYSGKGKVKIRIRRG
CCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECCCEEEEECCCCEEEEEEEEC
SIFYGKEEEEIKAILEKKSQYSVLQKNPEKEIGYFSIRQISVVYQNNSGGKKASEVELYG
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCCCCCCEEEEEE
SFSAIPGVPESLLTAGTFIQDYKQEIAYIEPGAFFTEDRRRTRPSKQLRHPKDGKEMVLV
CCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHCCCHHHHCCCCCCCEEEEE
SGGYEQNGEPFYESMGFFIHGQGNDPSEDSYNPFYFKPERGNLQDVSSFYIDKYEVTNQE
ECCCCCCCCHHHHCCCEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHEEECCHH
YSKFLKETNTSPPPHWKSGNFPAGKEHHPVSGITYREAETYARWSGKRLPTEMEWEKAAR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHC
GTGMTWKINRDESYSFFPSPLEYPFGNDFDSTLCNTIESKQNDTISVYELAKKSASPYGV
CCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCEE
IGMCGNIAEWTSSDYLPYPGHSLKRNTFGKMHKVIRGGSFSSTKEEATTYFRSFGGIPNL
EEECCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
KTDRRAGFRLVWDLPGK
CCCCCCCCEEEEECCCC
>Mature Secondary Structure 
TFDFKLKRFYFFLLFGSITFLFAQTQDSSLNTRMIPLWKGEVEAVYSGKGKVKIRIRRG
CCCHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECCCEEEEECCCCEEEEEEEEC
SIFYGKEEEEIKAILEKKSQYSVLQKNPEKEIGYFSIRQISVVYQNNSGGKKASEVELYG
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCCCCCCEEEEEE
SFSAIPGVPESLLTAGTFIQDYKQEIAYIEPGAFFTEDRRRTRPSKQLRHPKDGKEMVLV
CCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHCCCHHHHCCCCCCCEEEEE
SGGYEQNGEPFYESMGFFIHGQGNDPSEDSYNPFYFKPERGNLQDVSSFYIDKYEVTNQE
ECCCCCCCCHHHHCCCEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHEEECCHH
YSKFLKETNTSPPPHWKSGNFPAGKEHHPVSGITYREAETYARWSGKRLPTEMEWEKAAR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHC
GTGMTWKINRDESYSFFPSPLEYPFGNDFDSTLCNTIESKQNDTISVYELAKKSASPYGV
CCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCEE
IGMCGNIAEWTSSDYLPYPGHSLKRNTFGKMHKVIRGGSFSSTKEEATTYFRSFGGIPNL
EEECCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
KTDRRAGFRLVWDLPGK
CCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]