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The map label for this gene is nhaP

Identifier: 45659009

GI number: 45659009

Start: 3900969

End: 3902438

Strand: Reverse

Name: nhaP

Synonym: LIC13187

Alternate gene names: 45659009

Gene position: 3902438-3900969 (Counterclockwise)

Preceding gene: 45659010

Following gene: 45659008

Centisome position: 91.24

GC content: 37.48

Gene sequence:

>1470_bases
ATGGAATTTGAATTCAATACACTTATCTTATCAGGGTTAATCATACTCAGCATAGGACTTTTAAGAATTTCGTCCAAGTT
CGGAGTACCTTCTCTATTGTTATTTTTAATGATAGGAATGGCCGCCGGTTCGGATGGTCCGGGAGGAATTGATTTTGATA
ATCCGATTCTTGCAAGACAAGTAGGTTCCATAGCATTGGCGTATATTCTTTTTTCAGGAGGATTAGAAACCGAATGGCAA
AAGATCAGACCGGTTCTCTGGAAGGGAATCGTTTTAGGCAACTTAGGAGTGTTGATTACTTGGGCCGTAATGGGGCTGTT
CTCTGTTTATGTTTTAGGATTCTCACCGATTATAGGATTTTTGTTGGGAGCGGTCGTATCATCTACGGATGCGGCTGCTG
TATTCAATGTATTAAGAACTAGAAATACAGGAATGAAAAAAGGACTGACTTCCTTGCTCGAGTTAGAGTCTGGAAGTAAC
GATCCGTTAGCTGTTCTTTTAACCGTAAGTATATTAAGTCTTTTAGGCCCTCAGATACCGAAGGCAGAAGAATTAGTATT
TCATATTATTATACAATTTTCAATTGGGTCTGTAGCGGGAGCTCTATTTGGATACTTAATCTATAAAGGGCTTAATCGAA
TTAGGTTAGAATACGAAGGATTGTATCCAGTGTTGATTTCTGCTTCTGTATTATTTGTATATTCTGCTACGGAATTGATA
GGAGGGAATCCGTTTTTAGCTGTTTATATTGCGGGGCTTGTGTTAGGAAATCAATCCTTTGTTCATAAGCGGAGTAATTT
ACGATTCTTAGATGGGATTGCGTGGTTGATGCAAATTGTAATGTTCTTAACGTTAGGTTTGCTTGTTTATCCGAGTAGAA
TTCCTCCACTTTTCGGAACCGGAATTTTATTTTCTTGTTTTTTAGTATTCATTGCGAGACCAATTGCAGTGTTTATCTCT
TTAATTAAATCTGGATATAATTTCAAAGAAAAATTATTAGTATCTTGGATCGGACTTAGAGGTGCGGCGCCGATTATACT
TGCTACATTCCCGTTTGCTCAAGGAGTGGAAGGGTCAGATAAAATTTTTCATTTAGTATTTTTTACGGTACTCGTTTCTT
TGCTGATTCAAGGAACTAGTGTGCCTCAAGTGGTTCGATGGCTCGGGCTAGATGCGCCTTTAGAACAAAGAGCTTCTTAT
CCGTTCGAGTTTGAAAATAGGGAACAGAGTGATTCCAACCTACTTGAGTTTATCGTACCTTACGGATCGGATACGGTTGG
AAAATTTGTATATTCTTTAAATTTTCCGGAGAATTCGTTAATTACTCTAATTTATCGAGGAGACAAACATATTGTTCCAA
CAGGAAAAACTAAATTAGAAGAAGGTGATGTACTTTTGATTTTGACTCCAAAAGGGAGTGAAGATAAAATTCGAGAAATT
CTATCTAAAGTAGATTCAAGTCTGCCTTAA

Upstream 100 bases:

>100_bases
AAAGTCTGAAAGAAATTTTTGGAATGACAACTTTCATTAAAAAAAGGGAATGAGAATAAACTTATCTTTCGTATAAGATC
TAAAAAAGAAATTTTAAATA

Downstream 100 bases:

>100_bases
TAAATTATCCCAAAATCTAGAAAAGCATAAACATAATATTTTAGAAAATTCAATAAAAGGTTATAATTCTCCCAAGTAGT
TCTGTATCTGGAAGTTTTTG

Product: potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MEFEFNTLILSGLIILSIGLLRISSKFGVPSLLLFLMIGMAAGSDGPGGIDFDNPILARQVGSIALAYILFSGGLETEWQ
KIRPVLWKGIVLGNLGVLITWAVMGLFSVYVLGFSPIIGFLLGAVVSSTDAAAVFNVLRTRNTGMKKGLTSLLELESGSN
DPLAVLLTVSILSLLGPQIPKAEELVFHIIIQFSIGSVAGALFGYLIYKGLNRIRLEYEGLYPVLISASVLFVYSATELI
GGNPFLAVYIAGLVLGNQSFVHKRSNLRFLDGIAWLMQIVMFLTLGLLVYPSRIPPLFGTGILFSCFLVFIARPIAVFIS
LIKSGYNFKEKLLVSWIGLRGAAPIILATFPFAQGVEGSDKIFHLVFFTVLVSLLIQGTSVPQVVRWLGLDAPLEQRASY
PFEFENREQSDSNLLEFIVPYGSDTVGKFVYSLNFPENSLITLIYRGDKHIVPTGKTKLEEGDVLLILTPKGSEDKIREI
LSKVDSSLP

Sequences:

>Translated_489_residues
MEFEFNTLILSGLIILSIGLLRISSKFGVPSLLLFLMIGMAAGSDGPGGIDFDNPILARQVGSIALAYILFSGGLETEWQ
KIRPVLWKGIVLGNLGVLITWAVMGLFSVYVLGFSPIIGFLLGAVVSSTDAAAVFNVLRTRNTGMKKGLTSLLELESGSN
DPLAVLLTVSILSLLGPQIPKAEELVFHIIIQFSIGSVAGALFGYLIYKGLNRIRLEYEGLYPVLISASVLFVYSATELI
GGNPFLAVYIAGLVLGNQSFVHKRSNLRFLDGIAWLMQIVMFLTLGLLVYPSRIPPLFGTGILFSCFLVFIARPIAVFIS
LIKSGYNFKEKLLVSWIGLRGAAPIILATFPFAQGVEGSDKIFHLVFFTVLVSLLIQGTSVPQVVRWLGLDAPLEQRASY
PFEFENREQSDSNLLEFIVPYGSDTVGKFVYSLNFPENSLITLIYRGDKHIVPTGKTKLEEGDVLLILTPKGSEDKIREI
LSKVDSSLP
>Mature_489_residues
MEFEFNTLILSGLIILSIGLLRISSKFGVPSLLLFLMIGMAAGSDGPGGIDFDNPILARQVGSIALAYILFSGGLETEWQ
KIRPVLWKGIVLGNLGVLITWAVMGLFSVYVLGFSPIIGFLLGAVVSSTDAAAVFNVLRTRNTGMKKGLTSLLELESGSN
DPLAVLLTVSILSLLGPQIPKAEELVFHIIIQFSIGSVAGALFGYLIYKGLNRIRLEYEGLYPVLISASVLFVYSATELI
GGNPFLAVYIAGLVLGNQSFVHKRSNLRFLDGIAWLMQIVMFLTLGLLVYPSRIPPLFGTGILFSCFLVFIARPIAVFIS
LIKSGYNFKEKLLVSWIGLRGAAPIILATFPFAQGVEGSDKIFHLVFFTVLVSLLIQGTSVPQVVRWLGLDAPLEQRASY
PFEFENREQSDSNLLEFIVPYGSDTVGKFVYSLNFPENSLITLIYRGDKHIVPTGKTKLEEGDVLLILTPKGSEDKIREI
LSKVDSSLP

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=453, Percent_Identity=39.514348785872, Blast_Score=281, Evalue=8e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 53351; Mature: 53351

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFEFNTLILSGLIILSIGLLRISSKFGVPSLLLFLMIGMAAGSDGPGGIDFDNPILARQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
VGSIALAYILFSGGLETEWQKIRPVLWKGIVLGNLGVLITWAVMGLFSVYVLGFSPIIGF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGAVVSSTDAAAVFNVLRTRNTGMKKGLTSLLELESGSNDPLAVLLTVSILSLLGPQIP
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
KAEELVFHIIIQFSIGSVAGALFGYLIYKGLNRIRLEYEGLYPVLISASVLFVYSATELI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCHHHHHHHHHHHHEEHHHHH
GGNPFLAVYIAGLVLGNQSFVHKRSNLRFLDGIAWLMQIVMFLTLGLLVYPSRIPPLFGT
CCCCHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GILFSCFLVFIARPIAVFISLIKSGYNFKEKLLVSWIGLRGAAPIILATFPFAQGVEGSD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCH
KIFHLVFFTVLVSLLIQGTSVPQVVRWLGLDAPLEQRASYPFEFENREQSDSNLLEFIVP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCHHHHEEC
YGSDTVGKFVYSLNFPENSLITLIYRGDKHIVPTGKTKLEEGDVLLILTPKGSEDKIREI
CCCCCHHHEEEEECCCCCCEEEEEEECCEEECCCCCCCCCCCCEEEEECCCCCHHHHHHH
LSKVDSSLP
HHHHHCCCC
>Mature Secondary Structure
MEFEFNTLILSGLIILSIGLLRISSKFGVPSLLLFLMIGMAAGSDGPGGIDFDNPILARQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
VGSIALAYILFSGGLETEWQKIRPVLWKGIVLGNLGVLITWAVMGLFSVYVLGFSPIIGF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGAVVSSTDAAAVFNVLRTRNTGMKKGLTSLLELESGSNDPLAVLLTVSILSLLGPQIP
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
KAEELVFHIIIQFSIGSVAGALFGYLIYKGLNRIRLEYEGLYPVLISASVLFVYSATELI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCHHHHHHHHHHHHEEHHHHH
GGNPFLAVYIAGLVLGNQSFVHKRSNLRFLDGIAWLMQIVMFLTLGLLVYPSRIPPLFGT
CCCCHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GILFSCFLVFIARPIAVFISLIKSGYNFKEKLLVSWIGLRGAAPIILATFPFAQGVEGSD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCH
KIFHLVFFTVLVSLLIQGTSVPQVVRWLGLDAPLEQRASYPFEFENREQSDSNLLEFIVP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCHHHHEEC
YGSDTVGKFVYSLNFPENSLITLIYRGDKHIVPTGKTKLEEGDVLLILTPKGSEDKIREI
CCCCCHHHEEEEECCCCCCEEEEEEECCEEECCCCCCCCCCCCEEEEECCCCCHHHHHHH
LSKVDSSLP
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA