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The map label for this gene is recG [H]

Identifier: 45658972

GI number: 45658972

Start: 3860811

End: 3862985

Strand: Direct

Name: recG [H]

Synonym: LIC13150

Alternate gene names: 45658972

Gene position: 3860811-3862985 (Clockwise)

Preceding gene: 45658971

Following gene: 45658974

Centisome position: 90.27

GC content: 38.21

Gene sequence:

>2175_bases
ATGAAGAACTCGGTCTCTAAAACTGAAACCCAAAGCAACGGACTTCTTTTACCTGTAACAGTAATCAAAGGAGTTGGTCC
TTCCAAGGCGGCAGCGCTTGCGTCCATAGGAATTGATACCTTACAAGACCTTCTCAACTTTTTTCCGAGAAGATACTTAG
ATAGAAACCTAACCGACAACGTACTTTTAAAAACCGGCGAAACCGTAACCTTAATCGTAGAGGTTATAGACGCATACCTT
GCACACGGTAAAAAATCCAGACTTGTAGTCGGTACTAAAACCAGAAACAACGAAAGGATTTCGATCGTGTTTTTTCGTGG
TGTTAATTTTTTTCAAAAAATATTTCAACCAGGAACCACGTTAGTCGCCACAGGAAAATTGGAATACTTCCGAGGTTTTC
AACTGATCCATCCAGACTATGAAATTTTAACGAGTGCGATCAAAACTACTTATCCTATAAGTTCGACTGGTTCTAAAAAG
AAAAAACAGGAGCAAGAACCGGAAGAAGAATTGTCAGAACTTCCTGAAATGATCCATGCAGGTAGAATCATTCCTTTATA
TCCTTCAGGTGAAGTTCTCAAATCGGAAGGTCTTGATTCCAGAGGTTTTCGTAAAATTCTTTATTCCGCGTTGGAAAAAT
TAAAAGGTAAAATTCCGGAAATCCTTCCAAACGAAATTGTAAAACGAAGAGGTTTGATTCTAAGAGAAGAATCATACCGA
GAAATACATTTTCCGACGGATGAAAATTCTTTAGACACCGCGAAATACAGATTGAAATATGAAGAATTATTTTATTTTAA
TCTTCTAATTGAACATAAAAAGAAAGAACGGGAAAAAATCAAACGAGTACTTTGGCCTTTACCGGAATCAGAAACCGCAA
ACAAAGTTCGTAAAAATCTTCCGTTTCAACTTACAGAAGATCAAAACTCGGCGCTTCAAAAAATTAAGGAACTTACAAAT
AAAGAACAACCGATCGCCGTTCTTTTACAAGGTGACGTAGGTTCTGGAAAGACGTTAGTTGCTCTTTTGACTGCTTTGCG
TTATATAGATAACCAAATTCAAGTGTGTATGGTTGCACCGACTGAAATTCTCGCAAGACAACACTACCAGACCATTCTTT
CTTTTTTAGGTAACATGCCTTTTTTAGGAATCGAACTTTTAGTTGGCAAAGAACCTAAAAAAAACAGATACGAAAAACTC
TATAGAATTAAAAAAGGAGACACGTTATTTGTCATTGGAACACACAGTGTTTTTCAAGAAGACGTTTACTTTTCTGAGTT
AGGTCTTGTGATCATAGATGAACAACATAAGTTCGGAGTGGATCAAAGAGAAACTCTCCGTTCTAAAGGAAAGAACCCTG
ACATTCTCGCCATGACGGCAACCCCGATTCCTAGGACTCTTTGTTTAACCCTTTACGGAGACTTGGATCTTTTAACGATC
AAATCCAAACCCAAAGGTAGAATGCCGATTCAAACAAAATGGTTTCAGGAAGATCGAAGAGAAGGAATCTATAAATCCAT
TCGTAAATACGTTTCCTCCGGCAGACAATGTTATATCGTTTATCCATTGGTGGAAGAATCGGAAAAAGTAGATCTTAAGT
CTTGTATCGAGGCTTATGAATATTTGAAGCACGAAATCTTTCCTGACTTCGAAGTGGGACTTGTTCACGGTAAAATGGAA
GTGGAAGAAAAAGATCGTGTTATGCGAGAATTCTCCAAAAATAGAATTCAGATTTTAGTTTCTACGACCGTGATCGAAGT
CGGAATCGATGTACCGAACTCGACCGTTATGGTGATCGAACACGCGGATCGTTTTGGTATTTCCCAACTACATCAGCTGA
GAGGACGTGTAGGTAGAGGAGATCAAGAAAGCTTTTGTATTTTAATGACAGATTCCAAAGTTACAGAAGACGCAAAGGTC
AGATTAGAAGCAATGGTAAATTTTTCTGACGGATTTGCGTTATCCGAAATCGACCTTCAATTACGAGGTCCGGGTGAATT
GATGGGAGTTCGTCAAAGTGGTCTTCCAGATTTTAAAATTGCAGACTTAAGAAAAGATTCCAATCTAATAGAACTGACTA
GAGAAGACGCGACCTTATTTGGAAATCCGGGCGACTTGGAAAAAGAGGAAATTCGAGGTAGATTTAGTGAAGGAAGACTG
TTGTTTTCAAATTAG

Upstream 100 bases:

>100_bases
TGTAGATATTGTTATCTTGGATTAGAAGAAGAAACGGAAAATCGAAATTTGGTATCTTCTGAAATTCCCGATCCGGAATG
GACTCCAACGCCAATCAACG

Downstream 100 bases:

>100_bases
ATAAATAGTATATTTTCTGCTTAAGAGAACCTCTATAAAATCTAAAAAAACAATTAATCAAATTTCTGCATCAAATCGCT
GTTTTGTGGTCAACATCTCA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 724

Protein sequence:

>724_residues
MKNSVSKTETQSNGLLLPVTVIKGVGPSKAAALASIGIDTLQDLLNFFPRRYLDRNLTDNVLLKTGETVTLIVEVIDAYL
AHGKKSRLVVGTKTRNNERISIVFFRGVNFFQKIFQPGTTLVATGKLEYFRGFQLIHPDYEILTSAIKTTYPISSTGSKK
KKQEQEPEEELSELPEMIHAGRIIPLYPSGEVLKSEGLDSRGFRKILYSALEKLKGKIPEILPNEIVKRRGLILREESYR
EIHFPTDENSLDTAKYRLKYEELFYFNLLIEHKKKEREKIKRVLWPLPESETANKVRKNLPFQLTEDQNSALQKIKELTN
KEQPIAVLLQGDVGSGKTLVALLTALRYIDNQIQVCMVAPTEILARQHYQTILSFLGNMPFLGIELLVGKEPKKNRYEKL
YRIKKGDTLFVIGTHSVFQEDVYFSELGLVIIDEQHKFGVDQRETLRSKGKNPDILAMTATPIPRTLCLTLYGDLDLLTI
KSKPKGRMPIQTKWFQEDRREGIYKSIRKYVSSGRQCYIVYPLVEESEKVDLKSCIEAYEYLKHEIFPDFEVGLVHGKME
VEEKDRVMREFSKNRIQILVSTTVIEVGIDVPNSTVMVIEHADRFGISQLHQLRGRVGRGDQESFCILMTDSKVTEDAKV
RLEAMVNFSDGFALSEIDLQLRGPGELMGVRQSGLPDFKIADLRKDSNLIELTREDATLFGNPGDLEKEEIRGRFSEGRL
LFSN

Sequences:

>Translated_724_residues
MKNSVSKTETQSNGLLLPVTVIKGVGPSKAAALASIGIDTLQDLLNFFPRRYLDRNLTDNVLLKTGETVTLIVEVIDAYL
AHGKKSRLVVGTKTRNNERISIVFFRGVNFFQKIFQPGTTLVATGKLEYFRGFQLIHPDYEILTSAIKTTYPISSTGSKK
KKQEQEPEEELSELPEMIHAGRIIPLYPSGEVLKSEGLDSRGFRKILYSALEKLKGKIPEILPNEIVKRRGLILREESYR
EIHFPTDENSLDTAKYRLKYEELFYFNLLIEHKKKEREKIKRVLWPLPESETANKVRKNLPFQLTEDQNSALQKIKELTN
KEQPIAVLLQGDVGSGKTLVALLTALRYIDNQIQVCMVAPTEILARQHYQTILSFLGNMPFLGIELLVGKEPKKNRYEKL
YRIKKGDTLFVIGTHSVFQEDVYFSELGLVIIDEQHKFGVDQRETLRSKGKNPDILAMTATPIPRTLCLTLYGDLDLLTI
KSKPKGRMPIQTKWFQEDRREGIYKSIRKYVSSGRQCYIVYPLVEESEKVDLKSCIEAYEYLKHEIFPDFEVGLVHGKME
VEEKDRVMREFSKNRIQILVSTTVIEVGIDVPNSTVMVIEHADRFGISQLHQLRGRVGRGDQESFCILMTDSKVTEDAKV
RLEAMVNFSDGFALSEIDLQLRGPGELMGVRQSGLPDFKIADLRKDSNLIELTREDATLFGNPGDLEKEEIRGRFSEGRL
LFSN
>Mature_724_residues
MKNSVSKTETQSNGLLLPVTVIKGVGPSKAAALASIGIDTLQDLLNFFPRRYLDRNLTDNVLLKTGETVTLIVEVIDAYL
AHGKKSRLVVGTKTRNNERISIVFFRGVNFFQKIFQPGTTLVATGKLEYFRGFQLIHPDYEILTSAIKTTYPISSTGSKK
KKQEQEPEEELSELPEMIHAGRIIPLYPSGEVLKSEGLDSRGFRKILYSALEKLKGKIPEILPNEIVKRRGLILREESYR
EIHFPTDENSLDTAKYRLKYEELFYFNLLIEHKKKEREKIKRVLWPLPESETANKVRKNLPFQLTEDQNSALQKIKELTN
KEQPIAVLLQGDVGSGKTLVALLTALRYIDNQIQVCMVAPTEILARQHYQTILSFLGNMPFLGIELLVGKEPKKNRYEKL
YRIKKGDTLFVIGTHSVFQEDVYFSELGLVIIDEQHKFGVDQRETLRSKGKNPDILAMTATPIPRTLCLTLYGDLDLLTI
KSKPKGRMPIQTKWFQEDRREGIYKSIRKYVSSGRQCYIVYPLVEESEKVDLKSCIEAYEYLKHEIFPDFEVGLVHGKME
VEEKDRVMREFSKNRIQILVSTTVIEVGIDVPNSTVMVIEHADRFGISQLHQLRGRVGRGDQESFCILMTDSKVTEDAKV
RLEAMVNFSDGFALSEIDLQLRGPGELMGVRQSGLPDFKIADLRKDSNLIELTREDATLFGNPGDLEKEEIRGRFSEGRL
LFSN

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=692, Percent_Identity=36.5606936416185, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1787357, Length=383, Percent_Identity=39.9477806788512, Blast_Score=270, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 82560; Mature: 82560

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50817 INTEIN_N_TER ; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSVSKTETQSNGLLLPVTVIKGVGPSKAAALASIGIDTLQDLLNFFPRRYLDRNLTDN
CCCCCCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
VLLKTGETVTLIVEVIDAYLAHGKKSRLVVGTKTRNNERISIVFFRGVNFFQKIFQPGTT
EEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHCCCCE
LVATGKLEYFRGFQLIHPDYEILTSAIKTTYPISSTGSKKKKQEQEPEEELSELPEMIHA
EEEECCCHHHCCEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHC
GRIIPLYPSGEVLKSEGLDSRGFRKILYSALEKLKGKIPEILPNEIVKRRGLILREESYR
CCEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEECCCCC
EIHFPTDENSLDTAKYRLKYEELFYFNLLIEHKKKEREKIKRVLWPLPESETANKVRKNL
EEECCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
PFQLTEDQNSALQKIKELTNKEQPIAVLLQGDVGSGKTLVALLTALRYIDNQIQVCMVAP
CEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECC
TEILARQHYQTILSFLGNMPFLGIELLVGKEPKKNRYEKLYRIKKGDTLFVIGTHSVFQE
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECHHHHHH
DVYFSELGLVIIDEQHKFGVDQRETLRSKGKNPDILAMTATPIPRTLCLTLYGDLDLLTI
HHHHHHCCEEEEECCHHCCCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECCEEEEEE
KSKPKGRMPIQTKWFQEDRREGIYKSIRKYVSSGRQCYIVYPLVEESEKVDLKSCIEAYE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHH
YLKHEIFPDFEVGLVHGKMEVEEKDRVMREFSKNRIQILVSTTVIEVGIDVPNSTVMVIE
HHHHHCCCCCEEEEEECEECHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCCCEEEEEE
HADRFGISQLHQLRGRVGRGDQESFCILMTDSKVTEDAKVRLEAMVNFSDGFALSEIDLQ
CCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHEEEEEEEECCCCCEEEEEEEE
LRGPGELMGVRQSGLPDFKIADLRKDSNLIELTREDATLFGNPGDLEKEEIRGRFSEGRL
ECCCCCEECCCCCCCCCCEEECCCCCCCEEEEECCCCEEECCCCCCCHHHHCCCCCCCEE
LFSN
EECC
>Mature Secondary Structure
MKNSVSKTETQSNGLLLPVTVIKGVGPSKAAALASIGIDTLQDLLNFFPRRYLDRNLTDN
CCCCCCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
VLLKTGETVTLIVEVIDAYLAHGKKSRLVVGTKTRNNERISIVFFRGVNFFQKIFQPGTT
EEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHCCCCE
LVATGKLEYFRGFQLIHPDYEILTSAIKTTYPISSTGSKKKKQEQEPEEELSELPEMIHA
EEEECCCHHHCCEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHC
GRIIPLYPSGEVLKSEGLDSRGFRKILYSALEKLKGKIPEILPNEIVKRRGLILREESYR
CCEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEECCCCC
EIHFPTDENSLDTAKYRLKYEELFYFNLLIEHKKKEREKIKRVLWPLPESETANKVRKNL
EEECCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
PFQLTEDQNSALQKIKELTNKEQPIAVLLQGDVGSGKTLVALLTALRYIDNQIQVCMVAP
CEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECC
TEILARQHYQTILSFLGNMPFLGIELLVGKEPKKNRYEKLYRIKKGDTLFVIGTHSVFQE
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECHHHHHH
DVYFSELGLVIIDEQHKFGVDQRETLRSKGKNPDILAMTATPIPRTLCLTLYGDLDLLTI
HHHHHHCCEEEEECCHHCCCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECCEEEEEE
KSKPKGRMPIQTKWFQEDRREGIYKSIRKYVSSGRQCYIVYPLVEESEKVDLKSCIEAYE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHH
YLKHEIFPDFEVGLVHGKMEVEEKDRVMREFSKNRIQILVSTTVIEVGIDVPNSTVMVIE
HHHHHCCCCCEEEEEECEECHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCCCEEEEEE
HADRFGISQLHQLRGRVGRGDQESFCILMTDSKVTEDAKVRLEAMVNFSDGFALSEIDLQ
CCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHEEEEEEEECCCCCEEEEEEEE
LRGPGELMGVRQSGLPDFKIADLRKDSNLIELTREDATLFGNPGDLEKEEIRGRFSEGRL
ECCCCCEECCCCCCCCCCEEECCCCCCCEEEEECCCCEEECCCCCCCHHHHCCCCCCCEE
LFSN
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]