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The map label for this gene is gpsA

Identifier: 45658967

GI number: 45658967

Start: 3856799

End: 3857806

Strand: Reverse

Name: gpsA

Synonym: LIC13145

Alternate gene names: 45658967

Gene position: 3857806-3856799 (Counterclockwise)

Preceding gene: 45658973

Following gene: 45658966

Centisome position: 90.19

GC content: 38.89

Gene sequence:

>1008_bases
ATGAAAATTGGAGTGATCGGATCGGGAAGTTTTGGAACCGCGTTGGGAAGTCTTCTTGCGGATAAAGGTTATGAAGTTAC
TCTCTGGTGTAGAAATGATTCTCAAGTTGAAAGTATCAATCGCAATCATATCAATAACAAACATCTTCCTAATTTTACTC
TACCGGAAAAACTCACAGCAAGTAAGGATCTGAGAAACGTAGTTCAAGGAAAAGATATGATCGTATCTTCTCCACCTTCT
CATGCGCTAAGTGAAGTTTTAAGAGAAATCAAAGAATATTTACCAGAAAAAGTCCCTATCGTTTCCGCGAGTAAGGGAAT
TGAAAATGGAACGTTACGTCTTGTTTCCGAAATTTTTGAATCGGAACTTCCCGAAAAATATCATTCTTATCTTTCGTATT
TATCTGGACCTTCTTTTGCAAAAGAGATTATCCAAAAAGTACCGACCATTGTAAGTATTGCTTCTAAAAACGAAACGACC
GCACGTAAGGTTCAGGAAATATTCAGTTTTTTGTATTTTCGAACGTATTGGACTCCGGACGTGATCGGAGTAGAAGTGGG
AGGTTCTCTGAAGAATGTGATCGCTTTGGCTGCGGGCGTAAGTGATGGATTAGGTTTTGGACAAAATACAAGAGCTGCTT
TGATTACAAGAGGTTTGAATGAAATTACAAAAATAGGTTTGAAGTTGGGAGCTGATCCGATGACTTTTCTAGGACCTTCT
GGAATGGGAGATTTGATTTTGACTTGTTGTGGAGAACAATCTAGAAATCGTACCGTAGGGTTTCGATTAGGTAAGGGAGA
AACCTTGGAACAAATTCTTTCTAGCATGAACGAAGTTGCCGAAGGGGTAAAGACTACTCAAAGCGCGTATGAGTTATCAC
AGAAGTTGGGAATAGAAATGGCGATTACAAATGAAGTTTATAAAATGCTTTACGAAGGTAAGAATCCAAGAGAAGTTGTG
AAAGACCTTATGAAGCGCGATCTTAAAAGAGAGGGCGTTTCAGTCTGA

Upstream 100 bases:

>100_bases
GAAGAGTAAACTAAATTATTAATTCCAAGTTGGGAACGGTTGTTTCGAAATTGTTTGGTAGAAAAATTTTTTCGATTTTA
ACCTCACATGAGGAGTTTAC

Downstream 100 bases:

>100_bases
TCACTTTGAAACCTCTTTCCTTTAAATTTCATCTTTGTTTGGTTTTGAGTCTTGTATCTTTTAATTCGATTTCGACTCAA
ACTAAGCAGGAGTTTGGATG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKIGVIGSGSFGTALGSLLADKGYEVTLWCRNDSQVESINRNHINNKHLPNFTLPEKLTASKDLRNVVQGKDMIVSSPPS
HALSEVLREIKEYLPEKVPIVSASKGIENGTLRLVSEIFESELPEKYHSYLSYLSGPSFAKEIIQKVPTIVSIASKNETT
ARKVQEIFSFLYFRTYWTPDVIGVEVGGSLKNVIALAAGVSDGLGFGQNTRAALITRGLNEITKIGLKLGADPMTFLGPS
GMGDLILTCCGEQSRNRTVGFRLGKGETLEQILSSMNEVAEGVKTTQSAYELSQKLGIEMAITNEVYKMLYEGKNPREVV
KDLMKRDLKREGVSV

Sequences:

>Translated_335_residues
MKIGVIGSGSFGTALGSLLADKGYEVTLWCRNDSQVESINRNHINNKHLPNFTLPEKLTASKDLRNVVQGKDMIVSSPPS
HALSEVLREIKEYLPEKVPIVSASKGIENGTLRLVSEIFESELPEKYHSYLSYLSGPSFAKEIIQKVPTIVSIASKNETT
ARKVQEIFSFLYFRTYWTPDVIGVEVGGSLKNVIALAAGVSDGLGFGQNTRAALITRGLNEITKIGLKLGADPMTFLGPS
GMGDLILTCCGEQSRNRTVGFRLGKGETLEQILSSMNEVAEGVKTTQSAYELSQKLGIEMAITNEVYKMLYEGKNPREVV
KDLMKRDLKREGVSV
>Mature_335_residues
MKIGVIGSGSFGTALGSLLADKGYEVTLWCRNDSQVESINRNHINNKHLPNFTLPEKLTASKDLRNVVQGKDMIVSSPPS
HALSEVLREIKEYLPEKVPIVSASKGIENGTLRLVSEIFESELPEKYHSYLSYLSGPSFAKEIIQKVPTIVSIASKNETT
ARKVQEIFSFLYFRTYWTPDVIGVEVGGSLKNVIALAAGVSDGLGFGQNTRAALITRGLNEITKIGLKLGADPMTFLGPS
GMGDLILTCCGEQSRNRTVGFRLGKGETLEQILSSMNEVAEGVKTTQSAYELSQKLGIEMAITNEVYKMLYEGKNPREVV
KDLMKRDLKREGVSV

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=344, Percent_Identity=29.6511627906977, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI24307999, Length=345, Percent_Identity=29.5652173913043, Blast_Score=135, Evalue=4e-32,
Organism=Escherichia coli, GI1790037, Length=328, Percent_Identity=42.9878048780488, Blast_Score=281, Evalue=6e-77,
Organism=Caenorhabditis elegans, GI17507425, Length=318, Percent_Identity=28.6163522012579, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32564399, Length=346, Percent_Identity=29.4797687861272, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI32564403, Length=355, Percent_Identity=29.0140845070423, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI193210136, Length=355, Percent_Identity=29.0140845070423, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI193210134, Length=253, Percent_Identity=32.8063241106719, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324513, Length=339, Percent_Identity=28.9085545722714, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320181, Length=358, Percent_Identity=27.9329608938547, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI22026922, Length=350, Percent_Identity=26.8571428571429, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136202, Length=341, Percent_Identity=24.3401759530792, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17136200, Length=341, Percent_Identity=24.3401759530792, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17136204, Length=341, Percent_Identity=24.3401759530792, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45551945, Length=263, Percent_Identity=30.0380228136882, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362270, Length=263, Percent_Identity=30.0380228136882, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648969, Length=222, Percent_Identity=31.5315315315315, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36709; Mature: 36709

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGVIGSGSFGTALGSLLADKGYEVTLWCRNDSQVESINRNHINNKHLPNFTLPEKLTA
CEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHH
SKDLRNVVQGKDMIVSSPPSHALSEVLREIKEYLPEKVPIVSASKGIENGTLRLVSEIFE
HHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHH
SELPEKYHSYLSYLSGPSFAKEIIQKVPTIVSIASKNETTARKVQEIFSFLYFRTYWTPD
HHCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
VIGVEVGGSLKNVIALAAGVSDGLGFGQNTRAALITRGLNEITKIGLKLGADPMTFLGPS
EEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
GMGDLILTCCGEQSRNRTVGFRLGKGETLEQILSSMNEVAEGVKTTQSAYELSQKLGIEM
CCHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
AITNEVYKMLYEGKNPREVVKDLMKRDLKREGVSV
EHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIGVIGSGSFGTALGSLLADKGYEVTLWCRNDSQVESINRNHINNKHLPNFTLPEKLTA
CEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHH
SKDLRNVVQGKDMIVSSPPSHALSEVLREIKEYLPEKVPIVSASKGIENGTLRLVSEIFE
HHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHH
SELPEKYHSYLSYLSGPSFAKEIIQKVPTIVSIASKNETTARKVQEIFSFLYFRTYWTPD
HHCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
VIGVEVGGSLKNVIALAAGVSDGLGFGQNTRAALITRGLNEITKIGLKLGADPMTFLGPS
EEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
GMGDLILTCCGEQSRNRTVGFRLGKGETLEQILSSMNEVAEGVKTTQSAYELSQKLGIEM
CCHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
AITNEVYKMLYEGKNPREVVKDLMKRDLKREGVSV
EHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA