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The map label for this gene is murB

Identifier: 45658960

GI number: 45658960

Start: 3849035

End: 3850027

Strand: Reverse

Name: murB

Synonym: LIC13138

Alternate gene names: 45658960

Gene position: 3850027-3849035 (Counterclockwise)

Preceding gene: 45658961

Following gene: 45658955

Centisome position: 90.01

GC content: 36.05

Gene sequence:

>993_bases
GTGGTAGAGAATTGGGGAAGTTCATTTTTTATTCATATGTCTCCTGTTCTTTCCGAATCCCAACTTCGGGATTTTAAACA
TACCTTAGAATCTTCTAAAATACCTTTTCGTTCGGAAGTTAGATTGGGGATTTTGTCTTCCTTCAAAATTGGTGGTGTTT
GTCCTGTAATTGTCGAACCCGAAATTTCTTCCCAAGTTTCGGAAATCTTGCACATATTTTCTAAATTCGATATTCCTTGG
AAAATTTTAGGGGGAGGTTCTAATCTTTTGATTTCGGATCACCCTGATAATTTTGTTACTTTACGCTTGTCCGGTAAATT
TAAGGAGTTTGTATCTTTAGGTGATGGAAAGTTTAAAATTGGGGCCGCGACCAATACCACTCCTACGTTTCGTCAAATTT
CTCAGCTTGGTTATACGGGAGCAGAGTTTTTAAGTACAATTCCAGGTTGGACCGGTGGAGCAGTGATTCAAAATGCTGGT
TGTTACGGCGGAGAACTTTTTGATTTGATTGAATCCGTTGAATTTTTGAGAAACGGAGAAGTGTTTGTTCGTAAACCATC
TGAAATCAAATACGGTTATCGATTTACCGAATTTTTAAATCAAAAAGATTCCATTATTTTAGGAATTGAAATTCTTCTTA
AAGAAGGAAACTTAGAAGAGATTGAATCTTCTTTAAAAGATAAAAGAGATAGAAGAAACTCTTCTCAGCCCGAAAATAAA
AAAAGCGCGGGTTCTGTTTTTAAAAATCCCAAAGTTTTTCGTGAAGATGGAAAAGAAATTAAAGCTTGGGAATTGCTTGA
TCAAGCTGGTTTGAGAGGTCAGATCAAAGGTGGTGCTCAGATTTCTCCTGAACATTGTAATTTTATAGTCAATTTAGGAA
CGGCTACCGCTTCCGATGTACATTATCTGATTGATTTAGTTGTCGATAGGGTTTATCAAACGTCTGGAATTCTTTTAAAC
AGAGAGATCGAATTTTTCGGAGATATTCCTTAA

Upstream 100 bases:

>100_bases
GCAAAGTCGAGATAAATGGATTCTAACAATAGAAAAAACATAAATCACCTCTTTCTTTAAGATCGATCCGATTTCAGATT
TTCCTTGAGTTCTTTTTTTT

Downstream 100 bases:

>100_bases
TTTTTTTTCGGAGTTTTTACTATGAAGACGCTTAAAAATGAGTCTTTACTCTATCCATATACGTAAAAATAATATGGGTT
TTTACGCAAGTAATACTTAA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MVENWGSSFFIHMSPVLSESQLRDFKHTLESSKIPFRSEVRLGILSSFKIGGVCPVIVEPEISSQVSEILHIFSKFDIPW
KILGGGSNLLISDHPDNFVTLRLSGKFKEFVSLGDGKFKIGAATNTTPTFRQISQLGYTGAEFLSTIPGWTGGAVIQNAG
CYGGELFDLIESVEFLRNGEVFVRKPSEIKYGYRFTEFLNQKDSIILGIEILLKEGNLEEIESSLKDKRDRRNSSQPENK
KSAGSVFKNPKVFREDGKEIKAWELLDQAGLRGQIKGGAQISPEHCNFIVNLGTATASDVHYLIDLVVDRVYQTSGILLN
REIEFFGDIP

Sequences:

>Translated_330_residues
MVENWGSSFFIHMSPVLSESQLRDFKHTLESSKIPFRSEVRLGILSSFKIGGVCPVIVEPEISSQVSEILHIFSKFDIPW
KILGGGSNLLISDHPDNFVTLRLSGKFKEFVSLGDGKFKIGAATNTTPTFRQISQLGYTGAEFLSTIPGWTGGAVIQNAG
CYGGELFDLIESVEFLRNGEVFVRKPSEIKYGYRFTEFLNQKDSIILGIEILLKEGNLEEIESSLKDKRDRRNSSQPENK
KSAGSVFKNPKVFREDGKEIKAWELLDQAGLRGQIKGGAQISPEHCNFIVNLGTATASDVHYLIDLVVDRVYQTSGILLN
REIEFFGDIP
>Mature_330_residues
MVENWGSSFFIHMSPVLSESQLRDFKHTLESSKIPFRSEVRLGILSSFKIGGVCPVIVEPEISSQVSEILHIFSKFDIPW
KILGGGSNLLISDHPDNFVTLRLSGKFKEFVSLGDGKFKIGAATNTTPTFRQISQLGYTGAEFLSTIPGWTGGAVIQNAG
CYGGELFDLIESVEFLRNGEVFVRKPSEIKYGYRFTEFLNQKDSIILGIEILLKEGNLEEIESSLKDKRDRRNSSQPENK
KSAGSVFKNPKVFREDGKEIKAWELLDQAGLRGQIKGGAQISPEHCNFIVNLGTATASDVHYLIDLVVDRVYQTSGILLN
REIEFFGDIP

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=292, Percent_Identity=27.0547945205479, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 36760; Mature: 36760

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVENWGSSFFIHMSPVLSESQLRDFKHTLESSKIPFRSEVRLGILSSFKIGGVCPVIVEP
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECC
EISSQVSEILHIFSKFDIPWKILGGGSNLLISDHPDNFVTLRLSGKFKEFVSLGDGKFKI
CHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCEEEEEECCCHHHHHHCCCCCEEE
GAATNTTPTFRQISQLGYTGAEFLSTIPGWTGGAVIQNAGCYGGELFDLIESVEFLRNGE
ECCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCHHEECCCCCCHHHHHHHHHHHHHHCCC
VFVRKPSEIKYGYRFTEFLNQKDSIILGIEILLKEGNLEEIESSLKDKRDRRNSSQPENK
EEEECCCCCCCCCHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCH
KSAGSVFKNPKVFREDGKEIKAWELLDQAGLRGQIKGGAQISPEHCNFIVNLGTATASDV
HHHCHHHCCCHHHHHCCCHHHHHHHHHHCCCCEEECCCCEECHHHCEEEEEECCCCHHHH
HYLIDLVVDRVYQTSGILLNREIEFFGDIP
HHHHHHHHHHHHHHCCEEEEECCCCCCCCC
>Mature Secondary Structure
MVENWGSSFFIHMSPVLSESQLRDFKHTLESSKIPFRSEVRLGILSSFKIGGVCPVIVEP
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECC
EISSQVSEILHIFSKFDIPWKILGGGSNLLISDHPDNFVTLRLSGKFKEFVSLGDGKFKI
CHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCEEEEEECCCHHHHHHCCCCCEEE
GAATNTTPTFRQISQLGYTGAEFLSTIPGWTGGAVIQNAGCYGGELFDLIESVEFLRNGE
ECCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCHHEECCCCCCHHHHHHHHHHHHHHCCC
VFVRKPSEIKYGYRFTEFLNQKDSIILGIEILLKEGNLEEIESSLKDKRDRRNSSQPENK
EEEECCCCCCCCCHHHHHCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCH
KSAGSVFKNPKVFREDGKEIKAWELLDQAGLRGQIKGGAQISPEHCNFIVNLGTATASDV
HHHCHHHCCCHHHHHCCCHHHHHHHHHHCCCCEEECCCCEECHHHCEEEEEECCCCHHHH
HYLIDLVVDRVYQTSGILLNREIEFFGDIP
HHHHHHHHHHHHHHCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA