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The map label for this gene is tolC

Identifier: 45658957

GI number: 45658957

Start: 3843112

End: 3845142

Strand: Direct

Name: tolC

Synonym: LIC13135

Alternate gene names: 45658957

Gene position: 3843112-3845142 (Clockwise)

Preceding gene: 45658956

Following gene: 45658958

Centisome position: 89.85

GC content: 32.59

Gene sequence:

>2031_bases
TTGGAACAAACTCACAGAATTATTTCCATGAAAATAAATAGCAAATTCAAACAAATAAATCTTTATAGATTAGAAATAAA
TAAACATATTAATATACTAATATATTCTTTTAAAAAAATAACTCGAAAGTTCAAAATATTCCCAGAAAAATTCTATAAAA
TGAATTTAAAATTTGATGATAGTCGCAAAATGAAACTTTCATGTAAAAATTTGATTGGACAGTTATTTTTTTTAGACTTT
AGAAGGATTGATTTCAAAAACAATTTGCAACTTAAAAACTTTTTCTGTTACCAAATTTATCTTTTATCCTTATATAAATT
TTGGGACGAGTTTTCAAATACACATCGGATTTTTTCTGTAAAAAAAGAAAATAAATTTAAATTTTTTTCCAATTTTGGAA
ATTTCTGGAACATAAAATCCGAAAAGGCTATTTCTTTAAAAAAACTTAAATCTAAAATTATGTACACATTTTCAATAAAT
ACATTTATAAATAATTATAAACTTATATTCTATAACATAAATTCATTATTATTCCAAAAACATAAAGTATATTACAAAAA
GAAACCGAATGCAAAAAAAGTTTTAAAACTCCAAAACGTTTTTTTTACATTCATTTCTTTTTTTATATTAGTGTTTACAT
CTGAATGCACGGACGATTCCGGAATTCGAACAGGAGACGGAATTGTTGAACCCAGACTGGAAGAAGTAACCGGGATAACT
ACCGAAAAAATCAAAAGTATTTTACCTGAACAAGAACTGACTATAGATGAATTATATGCTTTCGCTGTAGAAAGAACGGA
AAGAATCGCTCTCAAGGAAGAAGCGATCCAACAGGCCGATGCTCAAAAGGCTGCCGCGTTCGCCTCCTTTTTTCCCTCTT
TATCTTTAGTGTATAATAAATTTTATAGAATTCCAGGGCCAAATTCCCATTTTAATCCTTTTTATACAGAACCAAATCCC
CTCACCGGAAGCTCTTCTACAACAAGCAGCCTCCCGCCCACGGTTGGCCCTGGAACGAGATTACTTTTGAGTATTCCAAT
CTTAAACGGAGTAAGTCAATATACTACTTATAAAGCCTCTGGCGCTTTAACCAACGTGAGACTGAACGAAGCTCGCTACG
AATCAGGAAGACTTTATCTAGAAATTGCACAAGCATATTATAATGTTCTACAATTAAAAGAAATCATTCTTTTAGAAGAA
AAAAAGACTGATTTGGTTCGTAAAACAATTCAAGAAAGAAGAAGACTTTTTTCCTTAGGAAAAATTACTAGAGCGGACTT
AAGTGGAGCCGAGGCTGATTTCTCCAGATCCGAAGCATACTTAGAAGATTTTAAATATCAATTAAAACAGGCGGAAATGG
CGCTGGAAAGCCTTATAGGAGCTGGAGAAGGTGGTCTACGATTAGCAATTCCTAAGGAAGTAATTTCCATTCCTAAAAAC
TTATTACCCGAAGAAAGAATCGCAAAACGATATGACGTAATCGCTGCAAAAGAAAATCTAAAGGCAGCGGAATTCAATCT
GAAAAAAGCCTGGGGCGGGCATTTACCTTCAGTTACATTAAACAATTATTATACAATTCCAGAACACAACACAACCCCAA
ATAAAGATATTACGATGCAACTATCTATCAACGTGCCTCTATTATCCGCTGGAATCGTCACAGCAGGAGTTAAACAGGCA
GAATCTGCATTAAGACAAGCAGAACTACAATTGTCTCAAACAAAAAGGATTGCGACTGATGAAATTCGAAAGGCATATGA
AAGCTCCTTAAATTCCGCTCGTTTATTATCCTTATATTCAAAAGCCCGCAATTCTGCAGAATCCAACCTAAGTTCTCAGA
GAAGAGGTTTCAGTTTTAAAACAGTTTCCCGTCTTGAACTTTTAGTATCAGAAACTTCTTTTTTAGATTCCGAAATTGCT
TATAGAAAGGCGTATTATCAACACTCTTTGAATACGATTTGGTATTCAGTTGCAATTGGCGAACTGCCAAAGTTAAAAAA
ATTAAAAGAAGAGGATAAGACTACAAATTAG

Upstream 100 bases:

>100_bases
TTACTCAGAATTATACAATAAAATACCTAATATTTTTTACTCAGAGGATATTGAAGTCATCAAAACTTATAAAAATTTGG
GAGCTCATACATTCTAAGTT

Downstream 100 bases:

>100_bases
TTTTCTTTGATGCTTGACATCTCTTCTCGATACTCTTAATTATTGGGCATAATTAGAGGTATAAACTCAATGATTATCAG
CAATTACTTTCAAGACAATG

Product: outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MEQTHRIISMKINSKFKQINLYRLEINKHINILIYSFKKITRKFKIFPEKFYKMNLKFDDSRKMKLSCKNLIGQLFFLDF
RRIDFKNNLQLKNFFCYQIYLLSLYKFWDEFSNTHRIFSVKKENKFKFFSNFGNFWNIKSEKAISLKKLKSKIMYTFSIN
TFINNYKLIFYNINSLLFQKHKVYYKKKPNAKKVLKLQNVFFTFISFFILVFTSECTDDSGIRTGDGIVEPRLEEVTGIT
TEKIKSILPEQELTIDELYAFAVERTERIALKEEAIQQADAQKAAAFASFFPSLSLVYNKFYRIPGPNSHFNPFYTEPNP
LTGSSSTTSSLPPTVGPGTRLLLSIPILNGVSQYTTYKASGALTNVRLNEARYESGRLYLEIAQAYYNVLQLKEIILLEE
KKTDLVRKTIQERRRLFSLGKITRADLSGAEADFSRSEAYLEDFKYQLKQAEMALESLIGAGEGGLRLAIPKEVISIPKN
LLPEERIAKRYDVIAAKENLKAAEFNLKKAWGGHLPSVTLNNYYTIPEHNTTPNKDITMQLSINVPLLSAGIVTAGVKQA
ESALRQAELQLSQTKRIATDEIRKAYESSLNSARLLSLYSKARNSAESNLSSQRRGFSFKTVSRLELLVSETSFLDSEIA
YRKAYYQHSLNTIWYSVAIGELPKLKKLKEEDKTTN

Sequences:

>Translated_676_residues
MEQTHRIISMKINSKFKQINLYRLEINKHINILIYSFKKITRKFKIFPEKFYKMNLKFDDSRKMKLSCKNLIGQLFFLDF
RRIDFKNNLQLKNFFCYQIYLLSLYKFWDEFSNTHRIFSVKKENKFKFFSNFGNFWNIKSEKAISLKKLKSKIMYTFSIN
TFINNYKLIFYNINSLLFQKHKVYYKKKPNAKKVLKLQNVFFTFISFFILVFTSECTDDSGIRTGDGIVEPRLEEVTGIT
TEKIKSILPEQELTIDELYAFAVERTERIALKEEAIQQADAQKAAAFASFFPSLSLVYNKFYRIPGPNSHFNPFYTEPNP
LTGSSSTTSSLPPTVGPGTRLLLSIPILNGVSQYTTYKASGALTNVRLNEARYESGRLYLEIAQAYYNVLQLKEIILLEE
KKTDLVRKTIQERRRLFSLGKITRADLSGAEADFSRSEAYLEDFKYQLKQAEMALESLIGAGEGGLRLAIPKEVISIPKN
LLPEERIAKRYDVIAAKENLKAAEFNLKKAWGGHLPSVTLNNYYTIPEHNTTPNKDITMQLSINVPLLSAGIVTAGVKQA
ESALRQAELQLSQTKRIATDEIRKAYESSLNSARLLSLYSKARNSAESNLSSQRRGFSFKTVSRLELLVSETSFLDSEIA
YRKAYYQHSLNTIWYSVAIGELPKLKKLKEEDKTTN
>Mature_676_residues
MEQTHRIISMKINSKFKQINLYRLEINKHINILIYSFKKITRKFKIFPEKFYKMNLKFDDSRKMKLSCKNLIGQLFFLDF
RRIDFKNNLQLKNFFCYQIYLLSLYKFWDEFSNTHRIFSVKKENKFKFFSNFGNFWNIKSEKAISLKKLKSKIMYTFSIN
TFINNYKLIFYNINSLLFQKHKVYYKKKPNAKKVLKLQNVFFTFISFFILVFTSECTDDSGIRTGDGIVEPRLEEVTGIT
TEKIKSILPEQELTIDELYAFAVERTERIALKEEAIQQADAQKAAAFASFFPSLSLVYNKFYRIPGPNSHFNPFYTEPNP
LTGSSSTTSSLPPTVGPGTRLLLSIPILNGVSQYTTYKASGALTNVRLNEARYESGRLYLEIAQAYYNVLQLKEIILLEE
KKTDLVRKTIQERRRLFSLGKITRADLSGAEADFSRSEAYLEDFKYQLKQAEMALESLIGAGEGGLRLAIPKEVISIPKN
LLPEERIAKRYDVIAAKENLKAAEFNLKKAWGGHLPSVTLNNYYTIPEHNTTPNKDITMQLSINVPLLSAGIVTAGVKQA
ESALRQAELQLSQTKRIATDEIRKAYESSLNSARLLSLYSKARNSAESNLSSQRRGFSFKTVSRLELLVSETSFLDSEIA
YRKAYYQHSLNTIWYSVAIGELPKLKKLKEEDKTTN

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 77981; Mature: 77981

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTHRIISMKINSKFKQINLYRLEINKHINILIYSFKKITRKFKIFPEKFYKMNLKFDD
CCCCCEEEEEEECCCEEEEEEEEEEECCCEEEEEEHHHHHHHHHHCCCCHHEEEECEECC
SRKMKLSCKNLIGQLFFLDFRRIDFKNNLQLKNFFCYQIYLLSLYKFWDEFSNTHRIFSV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KKENKFKFFSNFGNFWNIKSEKAISLKKLKSKIMYTFSINTFINNYKLIFYNINSLLFQK
ECCCCCHHHHCCCCEECCCCCHHHHHHHHHHHEEEEEEEEHHHCCEEEEEEEHHHHHHHH
HKVYYKKKPNAKKVLKLQNVFFTFISFFILVFTSECTDDSGIRTGDGIVEPRLEEVTGIT
HHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCC
TEKIKSILPEQELTIDELYAFAVERTERIALKEEAIQQADAQKAAAFASFFPSLSLVYNK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYRIPGPNSHFNPFYTEPNPLTGSSSTTSSLPPTVGPGTRLLLSIPILNGVSQYTTYKAS
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCHHHEEEECC
GALTNVRLNEARYESGRLYLEIAQAYYNVLQLKEIILLEEKKTDLVRKTIQERRRLFSLG
CCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
KITRADLSGAEADFSRSEAYLEDFKYQLKQAEMALESLIGAGEGGLRLAIPKEVISIPKN
CCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHCCHH
LLPEERIAKRYDVIAAKENLKAAEFNLKKAWGGHLPSVTLNNYYTIPEHNTTPNKDITMQ
CCCHHHHHHHHHHHHHHCCCCHHHCCHHHHCCCCCCCEEECCEEECCCCCCCCCCCEEEE
LSINVPLLSAGIVTAGVKQAESALRQAELQLSQTKRIATDEIRKAYESSLNSARLLSLYS
EEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KARNSAESNLSSQRRGFSFKTVSRLELLVSETSFLDSEIAYRKAYYQHSLNTIWYSVAIG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
ELPKLKKLKEEDKTTN
CCHHHHHHHHHCCCCC
>Mature Secondary Structure
MEQTHRIISMKINSKFKQINLYRLEINKHINILIYSFKKITRKFKIFPEKFYKMNLKFDD
CCCCCEEEEEEECCCEEEEEEEEEEECCCEEEEEEHHHHHHHHHHCCCCHHEEEECEECC
SRKMKLSCKNLIGQLFFLDFRRIDFKNNLQLKNFFCYQIYLLSLYKFWDEFSNTHRIFSV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KKENKFKFFSNFGNFWNIKSEKAISLKKLKSKIMYTFSINTFINNYKLIFYNINSLLFQK
ECCCCCHHHHCCCCEECCCCCHHHHHHHHHHHEEEEEEEEHHHCCEEEEEEEHHHHHHHH
HKVYYKKKPNAKKVLKLQNVFFTFISFFILVFTSECTDDSGIRTGDGIVEPRLEEVTGIT
HHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCC
TEKIKSILPEQELTIDELYAFAVERTERIALKEEAIQQADAQKAAAFASFFPSLSLVYNK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYRIPGPNSHFNPFYTEPNPLTGSSSTTSSLPPTVGPGTRLLLSIPILNGVSQYTTYKAS
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCHHHEEEECC
GALTNVRLNEARYESGRLYLEIAQAYYNVLQLKEIILLEEKKTDLVRKTIQERRRLFSLG
CCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
KITRADLSGAEADFSRSEAYLEDFKYQLKQAEMALESLIGAGEGGLRLAIPKEVISIPKN
CCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHCCHH
LLPEERIAKRYDVIAAKENLKAAEFNLKKAWGGHLPSVTLNNYYTIPEHNTTPNKDITMQ
CCCHHHHHHHHHHHHHHCCCCHHHCCHHHHCCCCCCCEEECCEEECCCCCCCCCCCEEEE
LSINVPLLSAGIVTAGVKQAESALRQAELQLSQTKRIATDEIRKAYESSLNSARLLSLYS
EEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KARNSAESNLSSQRRGFSFKTVSRLELLVSETSFLDSEIAYRKAYYQHSLNTIWYSVAIG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECC
ELPKLKKLKEEDKTTN
CCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]