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The map label for this gene is luxQ [H]

Identifier: 45658908

GI number: 45658908

Start: 3766557

End: 3768233

Strand: Direct

Name: luxQ [H]

Synonym: LIC13082

Alternate gene names: 45658908

Gene position: 3766557-3768233 (Clockwise)

Preceding gene: 45658907

Following gene: 45658912

Centisome position: 88.06

GC content: 34.94

Gene sequence:

>1677_bases
GTGAATACTTCAAACAACCATTCAGTTCCTATTCCACTTAACGAGACGGCAAGACTCCGCGCTCTACATTCTTATCAAAT
CCTAGACACGGCTTCGGAGGAAAAATTTGATTCATTAACTCAAATAGCAGCGTATATTTGCAATTCTTCGATGGCCTTGA
TTTCGTTAGTCGATACAAACCGACTTTGGTTTAAATCGAAATTGGGAATGCAAGAATCCGAAGCTCCTAGAAAAATTTCC
TTTTGTCAATATGCAATCATGAAGGACGATCTTTTAGAAATAGAAGATGCTCTGGAAAACGAAATATTTAAGAATAAACC
CTCCGTTTTAGGTCCCCCCTACATCCGTTTTTACGTGGGAGCCCCCTTAAAAACTCCGGATGGTTTTAATATAGGAACAC
TTTGTGTGTTCGACTCACAACCGAAACATTTAAATCCTAAACAAAGAGTCATTCTAAAAGCGTTATCAAATCAAATTATC
TATAACTTTGAACTAAATAAAAAAAATATAGAACTATTACTGATTCAAAAGAAAGAAGAAGAATTACAAAAATCTAAAAG
TCTGTTTTTTGCAAACATGAGCCACGAAATTCGTACTCCAGTTCACGGAATTTTAGGAGTTTCTGGTCTTTTATCGGAAA
CGGAATTACAACAAGAACAAAAAGAATACGTAGATACGATCCAGAGAAGCGGCAAGTTATTACTCAATCTTTTAAACGAT
ATATTAGATTTTTCTAAATTAGAATCATTCAATATGAAAATTGAAATCATAGCTTTTGATCTGATAGATTTGTTAAAAGA
CGTATTTCATCTTTTTGAGGCGGATGCAAAACGTAAAAATATAGAATTTAAATTAGTAGGAAAACAACCCTCTCACTCGA
TCGTATCTACAGATCCGCACAGATTTAAACAGATCTTAGTCAATCTTATTTCCAATGCCATCAAGTTCACCGAAAAAGGA
AGTGTATTGATCGAATTCGATTTCAAATCCGACTTAAAACATTGTGACATACAAATTCGAATAAAGGACACCGGCGTTGG
AATACCGGAACAAAAGCTTAAAGAATTATTCCAAGCCTACAGACAAGTAGACACGTCTGTTTCCAGAAAATATGGAGGAA
CCGGACTAGGTCTTTCAATCAGCAAAAACCTTTCAGAGATGATGAATTTAAAATTAACTGCGCGGAGCATTATTAATCAA
GGAAGTGTTTTTGAAATTTCGGGACAAATTCCACTCGCCGAAAAATCAGAAGTAAATTTTGAACCTAAAAAAGCGACCCA
AAATATAGAGATTCAAAATCTAAATATTCTAGTGGCAGAAGACAACGAAACCAATCAAATGCTAATCAAAAAGATTTTGG
AAAAACTAGGTTACAAACCTGTAATCGTTTCCAATGGAATAGAAGCGCTTCATCACATAAAAATGTATAAAACAGACGTT
TTATTTTTAGACATTCAGATGCCAGAACTGAACGGAATCGAAGCCGCTAAAATCCTAACACAACAAAACGATTCATCCAT
TCGTCCTTATATCATTGCAATGACGGCTAATGCTAGTCAAACGGATAAGGAAGATTGTATGGCCTCGGGAATCGACCAAT
ATCTCAGTAAGCCCTTTCACAAGGAAGAAATAGCAGACTTACTAAATCAATTTATTTCTCACAAAACAACAAATTGA

Upstream 100 bases:

>100_bases
TTTTCCAAAACATTTTCAAATTATCCGAATTTAGTTTTCCGATCAAAATTCCTCTTGCCTAATATTAGTTTTTAGTGAAA
ATGTTTTCGGTTTAGTTCCA

Downstream 100 bases:

>100_bases
TTCTCTTAGGACAGTTAGAAATTGCCTTAAAACCTAAAAATGTGGGAACTATTACAGTTTTAGATTGAACTTTGGAATTA
TAGTAATTACTACAAATTAT

Product: histidine kinase response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MNTSNNHSVPIPLNETARLRALHSYQILDTASEEKFDSLTQIAAYICNSSMALISLVDTNRLWFKSKLGMQESEAPRKIS
FCQYAIMKDDLLEIEDALENEIFKNKPSVLGPPYIRFYVGAPLKTPDGFNIGTLCVFDSQPKHLNPKQRVILKALSNQII
YNFELNKKNIELLLIQKKEEELQKSKSLFFANMSHEIRTPVHGILGVSGLLSETELQQEQKEYVDTIQRSGKLLLNLLND
ILDFSKLESFNMKIEIIAFDLIDLLKDVFHLFEADAKRKNIEFKLVGKQPSHSIVSTDPHRFKQILVNLISNAIKFTEKG
SVLIEFDFKSDLKHCDIQIRIKDTGVGIPEQKLKELFQAYRQVDTSVSRKYGGTGLGLSISKNLSEMMNLKLTARSIINQ
GSVFEISGQIPLAEKSEVNFEPKKATQNIEIQNLNILVAEDNETNQMLIKKILEKLGYKPVIVSNGIEALHHIKMYKTDV
LFLDIQMPELNGIEAAKILTQQNDSSIRPYIIAMTANASQTDKEDCMASGIDQYLSKPFHKEEIADLLNQFISHKTTN

Sequences:

>Translated_558_residues
MNTSNNHSVPIPLNETARLRALHSYQILDTASEEKFDSLTQIAAYICNSSMALISLVDTNRLWFKSKLGMQESEAPRKIS
FCQYAIMKDDLLEIEDALENEIFKNKPSVLGPPYIRFYVGAPLKTPDGFNIGTLCVFDSQPKHLNPKQRVILKALSNQII
YNFELNKKNIELLLIQKKEEELQKSKSLFFANMSHEIRTPVHGILGVSGLLSETELQQEQKEYVDTIQRSGKLLLNLLND
ILDFSKLESFNMKIEIIAFDLIDLLKDVFHLFEADAKRKNIEFKLVGKQPSHSIVSTDPHRFKQILVNLISNAIKFTEKG
SVLIEFDFKSDLKHCDIQIRIKDTGVGIPEQKLKELFQAYRQVDTSVSRKYGGTGLGLSISKNLSEMMNLKLTARSIINQ
GSVFEISGQIPLAEKSEVNFEPKKATQNIEIQNLNILVAEDNETNQMLIKKILEKLGYKPVIVSNGIEALHHIKMYKTDV
LFLDIQMPELNGIEAAKILTQQNDSSIRPYIIAMTANASQTDKEDCMASGIDQYLSKPFHKEEIADLLNQFISHKTTN
>Mature_558_residues
MNTSNNHSVPIPLNETARLRALHSYQILDTASEEKFDSLTQIAAYICNSSMALISLVDTNRLWFKSKLGMQESEAPRKIS
FCQYAIMKDDLLEIEDALENEIFKNKPSVLGPPYIRFYVGAPLKTPDGFNIGTLCVFDSQPKHLNPKQRVILKALSNQII
YNFELNKKNIELLLIQKKEEELQKSKSLFFANMSHEIRTPVHGILGVSGLLSETELQQEQKEYVDTIQRSGKLLLNLLND
ILDFSKLESFNMKIEIIAFDLIDLLKDVFHLFEADAKRKNIEFKLVGKQPSHSIVSTDPHRFKQILVNLISNAIKFTEKG
SVLIEFDFKSDLKHCDIQIRIKDTGVGIPEQKLKELFQAYRQVDTSVSRKYGGTGLGLSISKNLSEMMNLKLTARSIINQ
GSVFEISGQIPLAEKSEVNFEPKKATQNIEIQNLNILVAEDNETNQMLIKKILEKLGYKPVIVSNGIEALHHIKMYKTDV
LFLDIQMPELNGIEAAKILTQQNDSSIRPYIIAMTANASQTDKEDCMASGIDQYLSKPFHKEEIADLLNQFISHKTTN

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=375, Percent_Identity=33.8666666666667, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1788713, Length=370, Percent_Identity=37.027027027027, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1789149, Length=397, Percent_Identity=34.7607052896725, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI87081816, Length=398, Percent_Identity=30.9045226130653, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=36.5546218487395, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1786783, Length=212, Percent_Identity=28.3018867924528, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788393, Length=215, Percent_Identity=24.6511627906977, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786600, Length=243, Percent_Identity=24.2798353909465, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=248, Percent_Identity=24.5967741935484, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=212, Percent_Identity=25, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=24.8847926267281, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=204, Percent_Identity=25.9803921568627, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=127, Percent_Identity=29.9212598425197, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=120, Percent_Identity=29.1666666666667, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323034, Length=197, Percent_Identity=30.4568527918782, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63295; Mature: 63295

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSNNHSVPIPLNETARLRALHSYQILDTASEEKFDSLTQIAAYICNSSMALISLVDTN
CCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCC
RLWFKSKLGMQESEAPRKISFCQYAIMKDDLLEIEDALENEIFKNKPSVLGPPYIRFYVG
CEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEC
APLKTPDGFNIGTLCVFDSQPKHLNPKQRVILKALSNQIIYNFELNKKNIELLLIQKKEE
CCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECHHH
ELQKSKSLFFANMSHEIRTPVHGILGVSGLLSETELQQEQKEYVDTIQRSGKLLLNLLND
HHHHHHHEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILDFSKLESFNMKIEIIAFDLIDLLKDVFHLFEADAKRKNIEFKLVGKQPSHSIVSTDPH
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCHHCCCEEEEECCCCCCCCCCCCHH
RFKQILVNLISNAIKFTEKGSVLIEFDFKSDLKHCDIQIRIKDTGVGIPEQKLKELFQAY
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHH
RQVDTSVSRKYGGTGLGLSISKNLSEMMNLKLTARSIINQGSVFEISGQIPLAEKSEVNF
HHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCC
EPKKATQNIEIQNLNILVAEDNETNQMLIKKILEKLGYKPVIVSNGIEALHHIKMYKTDV
CCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHEECEE
LFLDIQMPELNGIEAAKILTQQNDSSIRPYIIAMTANASQTDKEDCMASGIDQYLSKPFH
EEEEEECCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCC
KEEIADLLNQFISHKTTN
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNTSNNHSVPIPLNETARLRALHSYQILDTASEEKFDSLTQIAAYICNSSMALISLVDTN
CCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCC
RLWFKSKLGMQESEAPRKISFCQYAIMKDDLLEIEDALENEIFKNKPSVLGPPYIRFYVG
CEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEC
APLKTPDGFNIGTLCVFDSQPKHLNPKQRVILKALSNQIIYNFELNKKNIELLLIQKKEE
CCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECHHH
ELQKSKSLFFANMSHEIRTPVHGILGVSGLLSETELQQEQKEYVDTIQRSGKLLLNLLND
HHHHHHHEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILDFSKLESFNMKIEIIAFDLIDLLKDVFHLFEADAKRKNIEFKLVGKQPSHSIVSTDPH
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCHHCCCEEEEECCCCCCCCCCCCHH
RFKQILVNLISNAIKFTEKGSVLIEFDFKSDLKHCDIQIRIKDTGVGIPEQKLKELFQAY
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHH
RQVDTSVSRKYGGTGLGLSISKNLSEMMNLKLTARSIINQGSVFEISGQIPLAEKSEVNF
HHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCC
EPKKATQNIEIQNLNILVAEDNETNQMLIKKILEKLGYKPVIVSNGIEALHHIKMYKTDV
CCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHEECEE
LFLDIQMPELNGIEAAKILTQQNDSSIRPYIIAMTANASQTDKEDCMASGIDQYLSKPFH
EEEEEECCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCC
KEEIADLLNQFISHKTTN
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA