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The map label for this gene is desA

Identifier: 45658879

GI number: 45658879

Start: 3726617

End: 3727714

Strand: Reverse

Name: desA

Synonym: LIC13053

Alternate gene names: 45658879

Gene position: 3727714-3726617 (Counterclockwise)

Preceding gene: 45658881

Following gene: 45658875

Centisome position: 87.15

GC content: 35.43

Gene sequence:

>1098_bases
ATGAAAGTGAAAAATAAAACAAATCATTCACCAAAAGAAACTTTAGGTTCGGTTCGGGAAATTCTTTCCGACGAAACTTT
TGCAAATCCAGCTTATAAGGGGGTTGGTTATTTTTTAAGAGATCTGTTTTTTTTCGTCATAGTAACGGTTTTACTTTGGA
ACGTAGATAGTTGGTATGTTCTTCCATTTTTATGGTTTTTTGCAGGAATGATCATTTCGGCTTTATTTGTAGTGGGACAT
GACTGCGCTCACGAAGCGTTGTTCAAAAGTAAGTTTCTTCAATACTGGATCGGACAAACTGCAATGCTTCCTTCTTTGCA
CGCATATAATCAATGGGGCTATGGCCATAATAGAATTCATCACGGTCATACGATCAAAAGACAAGCTGACTTCGTATGGC
ACCCAACTACTAAAGAGGAATATTCAGAATTCGGAATATTCAAAAAATTGATGCATCGATTTTTTTGGTCTATTTGGGGC
GGCGGTTTTTATTATATGATAGAAATTTGGTTTAAGGGAATGGTTTTATTTACAGCTCCTTTGAAAGAGGCTAAAAGAGA
TAAGTTGATTATGCTTTCTTTCGCGTTTATTTCATCGGGTTTGGTTTTTTATTTTGGAGCTTCTTCTATCCCCGGAGTTT
TTGATATTGGAACTGGTTTGTGGATGTTTACAAAGGTTTGTTTGATACCGTTTATCGCTTGGAATTATTTTATGGGGATT
ACGGTTTACGTACATCATATTCATTCGGAGATTCCTTGGAAAACGAAAGAAGAGTGGACTCCGTTTTATGGACAAATGAA
AGGAACCATCAACTACCATATCAATCCGATTATGAATTTTTTCTTCCATAATATTTTTATTCACATGCCTCATCACGTTC
ATATGAAAATTCCATTTTACAATTTAAAACGCGCTTTGAATGAGATTAAGGTTATTTATGGAGATTACGTTTTGGAAAGG
AATACGATCCTCGGAGATTATTTAAAATCAACTTCACTTTGTAAGGTGATCGATTCGGATACTGGTAAATGGATGACTTA
TAGAGAAGCCGAAGAGATGTCTCTAAAAGAGAAAGATTTGGAATCTATCCCAGTTTGA

Upstream 100 bases:

>100_bases
CTCAATTTTCAATTTGAAACAGTCATTTTTCTTGCCAAAAGATTCTATTTTAGTTAACATCGTTAATTATTAAAATGAAC
GATGTTCGTTAAGGAGAAAA

Downstream 100 bases:

>100_bases
TATTTCTTTAATGAGTCTGTCCCAAAATCTGCTCGGCGATTATAGGAACGAGAAGGCTTTAGTTTTCTCGAACTACCCAA
AACGCGATCCGTAAAAAACG

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(12)-desaturase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKVKNKTNHSPKETLGSVREILSDETFANPAYKGVGYFLRDLFFFVIVTVLLWNVDSWYVLPFLWFFAGMIISALFVVGH
DCAHEALFKSKFLQYWIGQTAMLPSLHAYNQWGYGHNRIHHGHTIKRQADFVWHPTTKEEYSEFGIFKKLMHRFFWSIWG
GGFYYMIEIWFKGMVLFTAPLKEAKRDKLIMLSFAFISSGLVFYFGASSIPGVFDIGTGLWMFTKVCLIPFIAWNYFMGI
TVYVHHIHSEIPWKTKEEWTPFYGQMKGTINYHINPIMNFFFHNIFIHMPHHVHMKIPFYNLKRALNEIKVIYGDYVLER
NTILGDYLKSTSLCKVIDSDTGKWMTYREAEEMSLKEKDLESIPV

Sequences:

>Translated_365_residues
MKVKNKTNHSPKETLGSVREILSDETFANPAYKGVGYFLRDLFFFVIVTVLLWNVDSWYVLPFLWFFAGMIISALFVVGH
DCAHEALFKSKFLQYWIGQTAMLPSLHAYNQWGYGHNRIHHGHTIKRQADFVWHPTTKEEYSEFGIFKKLMHRFFWSIWG
GGFYYMIEIWFKGMVLFTAPLKEAKRDKLIMLSFAFISSGLVFYFGASSIPGVFDIGTGLWMFTKVCLIPFIAWNYFMGI
TVYVHHIHSEIPWKTKEEWTPFYGQMKGTINYHINPIMNFFFHNIFIHMPHHVHMKIPFYNLKRALNEIKVIYGDYVLER
NTILGDYLKSTSLCKVIDSDTGKWMTYREAEEMSLKEKDLESIPV
>Mature_365_residues
MKVKNKTNHSPKETLGSVREILSDETFANPAYKGVGYFLRDLFFFVIVTVLLWNVDSWYVLPFLWFFAGMIISALFVVGH
DCAHEALFKSKFLQYWIGQTAMLPSLHAYNQWGYGHNRIHHGHTIKRQADFVWHPTTKEEYSEFGIFKKLMHRFFWSIWG
GGFYYMIEIWFKGMVLFTAPLKEAKRDKLIMLSFAFISSGLVFYFGASSIPGVFDIGTGLWMFTKVCLIPFIAWNYFMGI
TVYVHHIHSEIPWKTKEEWTPFYGQMKGTINYHINPIMNFFFHNIFIHMPHHVHMKIPFYNLKRALNEIKVIYGDYVLER
NTILGDYLKSTSLCKVIDSDTGKWMTYREAEEMSLKEKDLESIPV

Specific function: Can introduce a second cis double bond at the Delta(12) position of fatty acid bound to membranes glycerolipids. This enzyme is involved in chilling tolerance because the phase transition temperature of lipids of cellular membranes depends on the degree o

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 42961; Mature: 42961

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKNKTNHSPKETLGSVREILSDETFANPAYKGVGYFLRDLFFFVIVTVLLWNVDSWYV
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LPFLWFFAGMIISALFVVGHDCAHEALFKSKFLQYWIGQTAMLPSLHAYNQWGYGHNRIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCCCCCCCCCEE
HGHTIKRQADFVWHPTTKEEYSEFGIFKKLMHRFFWSIWGGGFYYMIEIWFKGMVLFTAP
CCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEECC
LKEAKRDKLIMLSFAFISSGLVFYFGASSIPGVFDIGTGLWMFTKVCLIPFIAWNYFMGI
HHHHCCCCEEEEEHHHHHCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TVYVHHIHSEIPWKTKEEWTPFYGQMKGTINYHINPIMNFFFHNIFIHMPHHVHMKIPFY
HHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEEHHHHHHHHHHHHHEECCCEEEEECCHH
NLKRALNEIKVIYGDYVLERNTILGDYLKSTSLCKVIDSDTGKWMTYREAEEMSLKEKDL
HHHHHHHHHHHHHHHEEEECCCHHHHHHHCCHHHHHHCCCCCCEEEECCHHHHHHHHHHH
ESIPV
HCCCC
>Mature Secondary Structure
MKVKNKTNHSPKETLGSVREILSDETFANPAYKGVGYFLRDLFFFVIVTVLLWNVDSWYV
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LPFLWFFAGMIISALFVVGHDCAHEALFKSKFLQYWIGQTAMLPSLHAYNQWGYGHNRIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHCCCCCCCCCEE
HGHTIKRQADFVWHPTTKEEYSEFGIFKKLMHRFFWSIWGGGFYYMIEIWFKGMVLFTAP
CCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEECC
LKEAKRDKLIMLSFAFISSGLVFYFGASSIPGVFDIGTGLWMFTKVCLIPFIAWNYFMGI
HHHHCCCCEEEEEHHHHHCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TVYVHHIHSEIPWKTKEEWTPFYGQMKGTINYHINPIMNFFFHNIFIHMPHHVHMKIPFY
HHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEEHHHHHHHHHHHHHEECCCEEEEECCHH
NLKRALNEIKVIYGDYVLERNTILGDYLKSTSLCKVIDSDTGKWMTYREAEEMSLKEKDL
HHHHHHHHHHHHHHHEEEECCCHHHHHHHCCHHHHHHCCCCCCEEEECCHHHHHHHHHHH
ESIPV
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA