Click here to switch to the map view.

The map label for this gene is 45658854

Identifier: 45658854

GI number: 45658854

Start: 3689502

End: 3690191

Strand: Direct

Name: 45658854

Synonym: LIC13027

Alternate gene names: NA

Gene position: 3689502-3690191 (Clockwise)

Preceding gene: 45658852

Following gene: 45658856

Centisome position: 86.26

GC content: 34.2

Gene sequence:

>690_bases
GTGAATTATCAAAAATATTTATTTTTAGATGTAGGAGATACAATTCTCCATCTAAAAAAATCCGCCGGAGAAACATATCT
TGAAATCCTTTTACAAGCAGGGTTACAAAAGAAAGAGAATGCGGGAGAGATTTACAGAAGAGCATTCACTGAGTCTTGGC
AAAAAATGCAAAAAAATTCTCCACCAGAACATAGAGATAAATACCAATTTCATTCAGGAGGAACTCCAGGTTGGTGGAAG
GAACTACTTGAAGATTTTTTGAAAAGAGTTCCAGACCAAGTCTCAATTGAAAAAGCGTTTCCGATTATATATCATAAATT
TGCAGACCCCGAACTATGGACCTTGGATCCAGGTTTTTGGAAACTTAAAGATTATTGTAAAGAAGAAAACTGGGGACTCG
GAGCAATTTCAAATTGGGATCACAGACTCAGAGCACTTTTAGAAGCAAAAGGAATATTAGAATATTTGAATCCTGTAATT
GTAAGTGCCGAATTTGGGTATGAAAAACCTTCTCCAAAAATATTTGAAGAAGCGATGCGTTTAGTAGGACTTTCGGGTGA
TTGTTTAGTTTACTGTGGCGATAAATACGAATTGGATATAAAAATACCAAAATCATTAGGTTGGAGGTCTTATTTAAAAG
GAGAAAAAGGAGATCTAAAAACTTTATCCGAGTTAATTCAATTTTTATAA

Upstream 100 bases:

>100_bases
TAAATTTAAAGAATAGATTATGTAAAGTGACTTACAAGTCATTTTTGATTTTAAAATTCTTACAGAGATGCAAAAAACCA
GGAGTAAATAAACTAGGTCT

Downstream 100 bases:

>100_bases
ATTAGATCTATAAAAGAAATCAAGATTGAAATCATGTGTTCTTTACAACCACAATCTTATACTTCAATTTCTGCTCAGAA
CTACATAATAAAAAACCAAA

Product: hypothetical protein

Products: (R)-2-hydroxyacid; halide

Alternate protein names: HAD Family Hydrolase; Hydrolase; Haloacid Dehalogenase Subfamily IA; HAD Superfamily Hydrolase; Haloacid Dehalogenase-Like Hydrolase; REG-2-Like HAD Superfamily Hydrolase

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNYQKYLFLDVGDTILHLKKSAGETYLEILLQAGLQKKENAGEIYRRAFTESWQKMQKNSPPEHRDKYQFHSGGTPGWWK
ELLEDFLKRVPDQVSIEKAFPIIYHKFADPELWTLDPGFWKLKDYCKEENWGLGAISNWDHRLRALLEAKGILEYLNPVI
VSAEFGYEKPSPKIFEEAMRLVGLSGDCLVYCGDKYELDIKIPKSLGWRSYLKGEKGDLKTLSELIQFL

Sequences:

>Translated_229_residues
MNYQKYLFLDVGDTILHLKKSAGETYLEILLQAGLQKKENAGEIYRRAFTESWQKMQKNSPPEHRDKYQFHSGGTPGWWK
ELLEDFLKRVPDQVSIEKAFPIIYHKFADPELWTLDPGFWKLKDYCKEENWGLGAISNWDHRLRALLEAKGILEYLNPVI
VSAEFGYEKPSPKIFEEAMRLVGLSGDCLVYCGDKYELDIKIPKSLGWRSYLKGEKGDLKTLSELIQFL
>Mature_229_residues
MNYQKYLFLDVGDTILHLKKSAGETYLEILLQAGLQKKENAGEIYRRAFTESWQKMQKNSPPEHRDKYQFHSGGTPGWWK
ELLEDFLKRVPDQVSIEKAFPIIYHKFADPELWTLDPGFWKLKDYCKEENWGLGAISNWDHRLRALLEAKGILEYLNPVI
VSAEFGYEKPSPKIFEEAMRLVGLSGDCLVYCGDKYELDIKIPKSLGWRSYLKGEKGDLKTLSELIQFL

Specific function: Unknown

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI13654294, Length=211, Percent_Identity=29.3838862559242, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17553988, Length=213, Percent_Identity=27.6995305164319, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19923000, Length=224, Percent_Identity=29.0178571428571, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.8.1.2

Molecular weight: Translated: 26658; Mature: 26658

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYQKYLFLDVGDTILHLKKSAGETYLEILLQAGLQKKENAGEIYRRAFTESWQKMQKNS
CCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
PPEHRDKYQFHSGGTPGWWKELLEDFLKRVPDQVSIEKAFPIIYHKFADPELWTLDPGFW
CCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCHH
KLKDYCKEENWGLGAISNWDHRLRALLEAKGILEYLNPVIVSAEFGYEKPSPKIFEEAMR
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHH
LVGLSGDCLVYCGDKYELDIKIPKSLGWRSYLKGEKGDLKTLSELIQFL
HHCCCCCEEEEECCEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MNYQKYLFLDVGDTILHLKKSAGETYLEILLQAGLQKKENAGEIYRRAFTESWQKMQKNS
CCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
PPEHRDKYQFHSGGTPGWWKELLEDFLKRVPDQVSIEKAFPIIYHKFADPELWTLDPGFW
CCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCHH
KLKDYCKEENWGLGAISNWDHRLRALLEAKGILEYLNPVIVSAEFGYEKPSPKIFEEAMR
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHH
LVGLSGDCLVYCGDKYELDIKIPKSLGWRSYLKGEKGDLKTLSELIQFL
HHCCCCCEEEEECCEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-haloacid; H2O

Specific reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA