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The map label for this gene is nadA

Identifier: 45658791

GI number: 45658791

Start: 3601920

End: 3602906

Strand: Reverse

Name: nadA

Synonym: LIC12964

Alternate gene names: 45658791

Gene position: 3602906-3601920 (Counterclockwise)

Preceding gene: 45658792

Following gene: 45658788

Centisome position: 84.24

GC content: 37.89

Gene sequence:

>987_bases
TTGGCCTTATCCATGAAAACTCTCGAAGAAGTTGCAAAAGCTCTTAAAAACACTTATATGGAACATGAGGTGGATGAAAA
ATTACCTCTGATCCAAGAAATTCAAAGATTAAAAAAAGAAAAGAACGCGATTCTCCTTGGTCATAACTATATGACTCCGG
ATGTGTTTCATGGTGTTTCGGATATTACCGGCGATTCTCTTTATCTGAGTAAAGTGGCAGCGGATACGGATGCGGATGTA
ATTCTTTTTAACGGGGTTCACTTTATGGCGGAGACAGCTAAGTTGATGTCTCCTCAAAAGAAAGTTCTCATTGCGGATCT
GAAGGCTGGTTGTTCTCTCGCGGAAAGTATTACTAGACAAGATGTAATTGATCTAAAACAAAAATATCCGGGTGTTCCTG
TCGTGACTTACGTCAATTGTACTGCGGATGTAAAGGCGGAGACAGATATTTGTTGTACATCGGCTAACGCTTTGCAGGTG
GTAGAATCTCTGGAAAGTGATACCGTGATTTTTTTACCAGATCGTTATTTGGCTGCGAACGTTCAAAATCTTACTCAGAA
AAAAATCATCACTCATCCAGGAAGTTGTATGGTTCATGAAATGTATTCTGCGGAAGACATTGAACTAACAAGAAGACAAT
TTCCTGGTGTTACAGTGATTTCTCATCCAGAATGTAAAACTGAAGTGGTGGATCGTTCGGATTATTCTGGTTCTACTTCT
CAGATGAGCGATTTTATCCGTAAGTCTGAAGCTAAAAATATTTTTTTAATTACCGAATGTTCTATGGGAGATAATCTTCG
TTCCGAATTTCCGGACAGACATTTTGTTTCTACTTGTCAGGTTTGCCCTCATATGAAAAAAATCACCCTCGAAAAAATCA
GAGATTCTTTGTTATACGATCAGTATGAAATTCATCTTGATCCGGAAGTGATCGAAAAAGGCAGAATGTCTGTTCAAAGA
ATGTTAGATCTTTCTTTTAAAAAATAA

Upstream 100 bases:

>100_bases
CAAATAGCGGGAATCTTTGGAGACAATGCCAGTCTAATTGTAACACGGGAACGAATTCTTCTTTTCCAAAGTTAAATGGG
ATTTCAACTACAACTACTTA

Downstream 100 bases:

>100_bases
AATCTGCATATACGGATTTCTATAAAATTGAGTGCTTTTAATTTTCATTACAAAACACTGTTTCGACGTAAAAATATTGG
GTATTTATTATATAATCTGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MALSMKTLEEVAKALKNTYMEHEVDEKLPLIQEIQRLKKEKNAILLGHNYMTPDVFHGVSDITGDSLYLSKVAADTDADV
ILFNGVHFMAETAKLMSPQKKVLIADLKAGCSLAESITRQDVIDLKQKYPGVPVVTYVNCTADVKAETDICCTSANALQV
VESLESDTVIFLPDRYLAANVQNLTQKKIITHPGSCMVHEMYSAEDIELTRRQFPGVTVISHPECKTEVVDRSDYSGSTS
QMSDFIRKSEAKNIFLITECSMGDNLRSEFPDRHFVSTCQVCPHMKKITLEKIRDSLLYDQYEIHLDPEVIEKGRMSVQR
MLDLSFKK

Sequences:

>Translated_328_residues
MALSMKTLEEVAKALKNTYMEHEVDEKLPLIQEIQRLKKEKNAILLGHNYMTPDVFHGVSDITGDSLYLSKVAADTDADV
ILFNGVHFMAETAKLMSPQKKVLIADLKAGCSLAESITRQDVIDLKQKYPGVPVVTYVNCTADVKAETDICCTSANALQV
VESLESDTVIFLPDRYLAANVQNLTQKKIITHPGSCMVHEMYSAEDIELTRRQFPGVTVISHPECKTEVVDRSDYSGSTS
QMSDFIRKSEAKNIFLITECSMGDNLRSEFPDRHFVSTCQVCPHMKKITLEKIRDSLLYDQYEIHLDPEVIEKGRMSVQR
MLDLSFKK
>Mature_327_residues
ALSMKTLEEVAKALKNTYMEHEVDEKLPLIQEIQRLKKEKNAILLGHNYMTPDVFHGVSDITGDSLYLSKVAADTDADVI
LFNGVHFMAETAKLMSPQKKVLIADLKAGCSLAESITRQDVIDLKQKYPGVPVVTYVNCTADVKAETDICCTSANALQVV
ESLESDTVIFLPDRYLAANVQNLTQKKIITHPGSCMVHEMYSAEDIELTRRQFPGVTVISHPECKTEVVDRSDYSGSTSQ
MSDFIRKSEAKNIFLITECSMGDNLRSEFPDRHFVSTCQVCPHMKKITLEKIRDSLLYDQYEIHLDPEVIEKGRMSVQRM
LDLSFKK

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=320, Percent_Identity=29.375, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 36964; Mature: 36833

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSMKTLEEVAKALKNTYMEHEVDEKLPLIQEIQRLKKEKNAILLGHNYMTPDVFHGVS
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHCHH
DITGDSLYLSKVAADTDADVILFNGVHFMAETAKLMSPQKKVLIADLKAGCSLAESITRQ
HCCCCCEEHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCHHEEEEHHHHCHHHHHHHHHH
DVIDLKQKYPGVPVVTYVNCTADVKAETDICCTSANALQVVESLESDTVIFLPDRYLAAN
HHHHHHHHCCCCCEEEEEECEECCCCCCCEEECCCHHHHHHHHCCCCEEEEECCHHHHHH
VQNLTQKKIITHPGSCMVHEMYSAEDIELTRRQFPGVTVISHPECKTEVVDRSDYSGSTS
HHHHHHHHHHCCCCCEEEEHHCCCCHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCHH
QMSDFIRKSEAKNIFLITECSMGDNLRSEFPDRHFVSTCQVCPHMKKITLEKIRDSLLYD
HHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCC
QYEIHLDPEVIEKGRMSVQRMLDLSFKK
CEEEEECHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALSMKTLEEVAKALKNTYMEHEVDEKLPLIQEIQRLKKEKNAILLGHNYMTPDVFHGVS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHCHH
DITGDSLYLSKVAADTDADVILFNGVHFMAETAKLMSPQKKVLIADLKAGCSLAESITRQ
HCCCCCEEHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCHHEEEEHHHHCHHHHHHHHHH
DVIDLKQKYPGVPVVTYVNCTADVKAETDICCTSANALQVVESLESDTVIFLPDRYLAAN
HHHHHHHHCCCCCEEEEEECEECCCCCCCEEECCCHHHHHHHHCCCCEEEEECCHHHHHH
VQNLTQKKIITHPGSCMVHEMYSAEDIELTRRQFPGVTVISHPECKTEVVDRSDYSGSTS
HHHHHHHHHHCCCCCEEEEHHCCCCHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCHH
QMSDFIRKSEAKNIFLITECSMGDNLRSEFPDRHFVSTCQVCPHMKKITLEKIRDSLLYD
HHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCC
QYEIHLDPEVIEKGRMSVQRMLDLSFKK
CEEEEECHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA