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The map label for this gene is bcsA [H]

Identifier: 45658787

GI number: 45658787

Start: 3591745

End: 3593295

Strand: Reverse

Name: bcsA [H]

Synonym: LIC12960

Alternate gene names: 45658787

Gene position: 3593295-3591745 (Counterclockwise)

Preceding gene: 45658788

Following gene: 45658785

Centisome position: 84.01

GC content: 37.72

Gene sequence:

>1551_bases
ATGCTGACCGTCGTAACTATATTGTTTCTGGCTATTTATGGGATCGACATAGTCGCTCTCTTTTTCTTTGGGATTCATAC
CTATATCATGGTATACCTTTATAAAAAGAACCATACATATTGTGAATCCGAGCCAGACAAAATTTTAGACATCAACAATC
CAAATCTGCCAGTAGTGACTGTGCAATTACCGATTTTCAACGAATATTATGTAGTGGACCGATTGATTGAAACAACTGTC
GCACTTAAATATCCGAAAGATAAACTTGAAATACAACTTTTAGATGATTCTACAGACGAGACTGTCGAAAAGTCTAGAAA
TCTAATCAACCATTATAAATCACTTGGATTTGACATTCATCATCTTCATCGATCAGGGGCGGAGCGTACCGGACACAAGG
CCGGGGCTTTAGAAGCGGGGATGAAAGTTGCTAGAGGAGAATACATCGCAATTTTTGACGCGGACTTTATGCCGAATCCT
GATTTCTTAATTAAAACCGTGCCATATTTTGATGATCCTCAGATTGGAATGGTACAAGTTCGTTGGGGACATATCAACGC
GGACTATAATGTTCTTACCAAAGCACAATCTTTTGGAATCGATGGACATTTTATGATCGAGCAGGTTGCCAGAAATGGAT
CTCATCTTTGGATGAATTTCAATGGGACTGCTGGAATTTGGAAAAAAGAATGTATTATTGATTCCGGTGGATGGGAACAC
GATACTCTTACGGAAGATTTTGATCTTTCTTACCGCGCAGAAATGAAGGGATGGAAATTCCGCTATTTTAAAGATATTGA
ATGTAAGGCCGAGATTCCAGCAATGATTTCTGCGTATAAATCACAGCAATTCCGTTGGTGTAAAGGTTCTATACAAACTG
CCGTCAAGTTGCTTCCAAGAATTCTTCGTGCAGATCTTCCTTGGAGAATTAAGTCAGAGGCGATTGTTCACTTAATTAAT
TATTCGGTTCATCCTTTAATGGTGATCAATATACTTTTCAGTGCTCCTTTGTTGCTGATGGACTACTGGTCTGGTTTCAG
CTTCTATGATTTACCAATTGAAATTTTAATGGGAACTGCGGCAATTTTATCGGTAGGATCTGTCGGTCCTATGATCTTCT
ATGCGTATTCTCAGAAAATTCTTCATAAAGATTGGAAAAAAAGAATGTTATATCTTCCAATTTTAATTATGATCGGAACT
GGAATTGCGATTGTAAACACAAGAGCTTGGTTAGAAGCGATACTTGGGATTCAATCTTCATTCAAACGTACTCCTAAACT
TAAGATCGAAAAGAATACGGATATATTGAAAGAAAGACTGAAATATACTGTGCCTTTGGATTTTCATGTGGTGCTTGAAT
TTCTAATGGGGTTTTATTGTATTGGGACCGTTTTTCTTTCTTTTGCACTCGGAAAGCCTCAGATTGTAGGTTTCTTAATG
ATTTATGCACTCGGATTTTTCTATGTGGGATATTTATCTTTGAAAGATGCACTCTGGAAATTGGGAGCTTCTAAGCAAGA
ATCTGCAAAAGAACTTTCTACCCAGGCATAA

Upstream 100 bases:

>100_bases
CTTCTGAATAAAAAATAAAGGACCAAATTAAAAAACTAAAAAATTTATGCAGTGCAAAATCTTTGACTTTTAACGAGAAG
AATATTTCCTGGCTATCATT

Downstream 100 bases:

>100_bases
GGATAAAAACAAAACAAGGCTAAAGAGCTTTTTTTAGCTTTGTTTTTTTGAAAAGAAAATCAGTTTTTTCCATAAATCGG
CCTCTATTAAAATTCAAAAA

Product: glycosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MLTVVTILFLAIYGIDIVALFFFGIHTYIMVYLYKKNHTYCESEPDKILDINNPNLPVVTVQLPIFNEYYVVDRLIETTV
ALKYPKDKLEIQLLDDSTDETVEKSRNLINHYKSLGFDIHHLHRSGAERTGHKAGALEAGMKVARGEYIAIFDADFMPNP
DFLIKTVPYFDDPQIGMVQVRWGHINADYNVLTKAQSFGIDGHFMIEQVARNGSHLWMNFNGTAGIWKKECIIDSGGWEH
DTLTEDFDLSYRAEMKGWKFRYFKDIECKAEIPAMISAYKSQQFRWCKGSIQTAVKLLPRILRADLPWRIKSEAIVHLIN
YSVHPLMVINILFSAPLLLMDYWSGFSFYDLPIEILMGTAAILSVGSVGPMIFYAYSQKILHKDWKKRMLYLPILIMIGT
GIAIVNTRAWLEAILGIQSSFKRTPKLKIEKNTDILKERLKYTVPLDFHVVLEFLMGFYCIGTVFLSFALGKPQIVGFLM
IYALGFFYVGYLSLKDALWKLGASKQESAKELSTQA

Sequences:

>Translated_516_residues
MLTVVTILFLAIYGIDIVALFFFGIHTYIMVYLYKKNHTYCESEPDKILDINNPNLPVVTVQLPIFNEYYVVDRLIETTV
ALKYPKDKLEIQLLDDSTDETVEKSRNLINHYKSLGFDIHHLHRSGAERTGHKAGALEAGMKVARGEYIAIFDADFMPNP
DFLIKTVPYFDDPQIGMVQVRWGHINADYNVLTKAQSFGIDGHFMIEQVARNGSHLWMNFNGTAGIWKKECIIDSGGWEH
DTLTEDFDLSYRAEMKGWKFRYFKDIECKAEIPAMISAYKSQQFRWCKGSIQTAVKLLPRILRADLPWRIKSEAIVHLIN
YSVHPLMVINILFSAPLLLMDYWSGFSFYDLPIEILMGTAAILSVGSVGPMIFYAYSQKILHKDWKKRMLYLPILIMIGT
GIAIVNTRAWLEAILGIQSSFKRTPKLKIEKNTDILKERLKYTVPLDFHVVLEFLMGFYCIGTVFLSFALGKPQIVGFLM
IYALGFFYVGYLSLKDALWKLGASKQESAKELSTQA
>Mature_516_residues
MLTVVTILFLAIYGIDIVALFFFGIHTYIMVYLYKKNHTYCESEPDKILDINNPNLPVVTVQLPIFNEYYVVDRLIETTV
ALKYPKDKLEIQLLDDSTDETVEKSRNLINHYKSLGFDIHHLHRSGAERTGHKAGALEAGMKVARGEYIAIFDADFMPNP
DFLIKTVPYFDDPQIGMVQVRWGHINADYNVLTKAQSFGIDGHFMIEQVARNGSHLWMNFNGTAGIWKKECIIDSGGWEH
DTLTEDFDLSYRAEMKGWKFRYFKDIECKAEIPAMISAYKSQQFRWCKGSIQTAVKLLPRILRADLPWRIKSEAIVHLIN
YSVHPLMVINILFSAPLLLMDYWSGFSFYDLPIEILMGTAAILSVGSVGPMIFYAYSQKILHKDWKKRMLYLPILIMIGT
GIAIVNTRAWLEAILGIQSSFKRTPKLKIEKNTDILKERLKYTVPLDFHVVLEFLMGFYCIGTVFLSFALGKPQIVGFLM
IYALGFFYVGYLSLKDALWKLGASKQESAKELSTQA

Specific function: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component responsible for the structural integrity and rigidity of self-supporting mats characteristic of the "wrink

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

Organism=Escherichia coli, GI87082284, Length=243, Percent_Identity=26.7489711934156, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1787259, Length=282, Percent_Identity=23.0496453900709, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003919
- InterPro:   IPR005150
- InterPro:   IPR001173
- InterPro:   IPR009875 [H]

Pfam domain/function: PF03552 Cellulose_synt; PF00535 Glycos_transf_2; PF07238 PilZ [H]

EC number: =2.4.1.12 [H]

Molecular weight: Translated: 59098; Mature: 59098

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTVVTILFLAIYGIDIVALFFFGIHTYIMVYLYKKNHTYCESEPDKILDINNPNLPVVT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEECCCCCCCEEE
VQLPIFNEYYVVDRLIETTVALKYPKDKLEIQLLDDSTDETVEKSRNLINHYKSLGFDIH
EEECCCCCHHHHHHHHHHHHHEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHH
HLHRSGAERTGHKAGALEAGMKVARGEYIAIFDADFMPNPDFLIKTVPYFDDPQIGMVQV
HHHHCCCHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCEEEE
RWGHINADYNVLTKAQSFGIDGHFMIEQVARNGSHLWMNFNGTAGIWKKECIIDSGGWEH
EEEEECCCCHHEEHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCC
DTLTEDFDLSYRAEMKGWKFRYFKDIECKAEIPAMISAYKSQQFRWCKGSIQTAVKLLPR
CCCCCCCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ILRADLPWRIKSEAIVHLINYSVHPLMVINILFSAPLLLMDYWSGFSFYDLPIEILMGTA
HHHCCCCCEECHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHCCCCEECCHHHHHHHHH
AILSVGSVGPMIFYAYSQKILHKDWKKRMLYLPILIMIGTGIAIVNTRAWLEAILGIQSS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHH
FKRTPKLKIEKNTDILKERLKYTVPLDFHVVLEFLMGFYCIGTVFLSFALGKPQIVGFLM
HCCCCCEEEECCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IYALGFFYVGYLSLKDALWKLGASKQESAKELSTQA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MLTVVTILFLAIYGIDIVALFFFGIHTYIMVYLYKKNHTYCESEPDKILDINNPNLPVVT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEECCCCCCCEEE
VQLPIFNEYYVVDRLIETTVALKYPKDKLEIQLLDDSTDETVEKSRNLINHYKSLGFDIH
EEECCCCCHHHHHHHHHHHHHEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHH
HLHRSGAERTGHKAGALEAGMKVARGEYIAIFDADFMPNPDFLIKTVPYFDDPQIGMVQV
HHHHCCCHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCEEEE
RWGHINADYNVLTKAQSFGIDGHFMIEQVARNGSHLWMNFNGTAGIWKKECIIDSGGWEH
EEEEECCCCHHEEHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCC
DTLTEDFDLSYRAEMKGWKFRYFKDIECKAEIPAMISAYKSQQFRWCKGSIQTAVKLLPR
CCCCCCCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ILRADLPWRIKSEAIVHLINYSVHPLMVINILFSAPLLLMDYWSGFSFYDLPIEILMGTA
HHHCCCCCEECHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHCCCCEECCHHHHHHHHH
AILSVGSVGPMIFYAYSQKILHKDWKKRMLYLPILIMIGTGIAIVNTRAWLEAILGIQSS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHH
FKRTPKLKIEKNTDILKERLKYTVPLDFHVVLEFLMGFYCIGTVFLSFALGKPQIVGFLM
HCCCCCEEEECCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IYALGFFYVGYLSLKDALWKLGASKQESAKELSTQA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12019221 [H]