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The map label for this gene is aroE

Identifier: 45658777

GI number: 45658777

Start: 3580082

End: 3581023

Strand: Direct

Name: aroE

Synonym: LIC12949

Alternate gene names: 45658777

Gene position: 3580082-3581023 (Clockwise)

Preceding gene: 45658775

Following gene: 45658778

Centisome position: 83.7

GC content: 34.18

Gene sequence:

>942_bases
TTGCATTTAACAAGAAACGAATCGAAAAAATTGAATCTTGTTTGTAAAATTCACAAAGAGAAAATTGAAATGAAAACTAA
AACAAATCAATCTGTTAAAACTTTCGGTATAGTAGGATTTCCTCTTTCACATTCTCTTTCTCCTCTAATTCATAATTCAA
TTTATAAAGATAGAAATATAAACGCCTCTTATCTCGTTTTTGAAACTCAAAACCTAAATGTAGAAAAAATACAAGAATTC
CGAAACTCTGGAATTTTAGGACTTTCTGTAACCATTCCTCATAAAGAAACCGCTTTTACTCTCGCAGATAAAGCAGATGA
CACATCTAGAATTATGAAAGCTTCCAACACGTTGTTGATCGGACCGGATTCAACTTATGCATACAACACCGATGGAGAAG
GCGCCTATCATTCTATCTTAGAATTTTCTCCAGAATCCTTAAAAACCGGAAAGGTAGTAATCTTAGGAAGCGGCGGAAGC
GCGAGAGGAATTGCATTTAGTCTTGCAGTTTCGGGTAAAATTCAAAACTTACTTGTATGTTCCAGAAATGAAATCACTGC
AAAAGAAATTTGTTTATTAGTTACTAAAAATTCAAATGTAAAAGCGGAACCAATTTCGCAAGATGTATTACTTACTCGAA
AAGAAGAAATTTCATTAGTAATTCATACAACTCCTTTGGGAATGAAGGGACAATCACCAGGTCCGTATCTTCCCGAAGAT
TTTTTTAACTCGAACATGACTCTTTTCGATATAGTTTATAATCCTTTAGAAACTCCTTTGGTAAAAGCCGCACAAAAAGC
GGGAGCAAAAATCATTCCAGGATCGGAGATGCTTTTATATCAAGCAATGAAACAGTTCGAACTTTTTACAGAAATTTCGC
CTAACGCAGAAGATATAATCAAAACCAGGGAACGTTTGTCTAAAGCATTAGAAAATCGATGA

Upstream 100 bases:

>100_bases
CAGCATTTTCGGGAATTGTCTTTTTAGTCGACTCATTTTACTACTCGTTCTAAAACTTGCTCCTTTTGGAGCAAAAAAGT
CAAAAGTTTAGAGTGATTCC

Downstream 100 bases:

>100_bases
ATTCAGATTCCGACTTTTTAGAATTTGCAAACGGACTTTCTAATTTAGAAAAAAGCAGAAACTTCAATGTTTTTGCCGGT
TATTCCTTGGAACCATTTAC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MHLTRNESKKLNLVCKIHKEKIEMKTKTNQSVKTFGIVGFPLSHSLSPLIHNSIYKDRNINASYLVFETQNLNVEKIQEF
RNSGILGLSVTIPHKETAFTLADKADDTSRIMKASNTLLIGPDSTYAYNTDGEGAYHSILEFSPESLKTGKVVILGSGGS
ARGIAFSLAVSGKIQNLLVCSRNEITAKEICLLVTKNSNVKAEPISQDVLLTRKEEISLVIHTTPLGMKGQSPGPYLPED
FFNSNMTLFDIVYNPLETPLVKAAQKAGAKIIPGSEMLLYQAMKQFELFTEISPNAEDIIKTRERLSKALENR

Sequences:

>Translated_313_residues
MHLTRNESKKLNLVCKIHKEKIEMKTKTNQSVKTFGIVGFPLSHSLSPLIHNSIYKDRNINASYLVFETQNLNVEKIQEF
RNSGILGLSVTIPHKETAFTLADKADDTSRIMKASNTLLIGPDSTYAYNTDGEGAYHSILEFSPESLKTGKVVILGSGGS
ARGIAFSLAVSGKIQNLLVCSRNEITAKEICLLVTKNSNVKAEPISQDVLLTRKEEISLVIHTTPLGMKGQSPGPYLPED
FFNSNMTLFDIVYNPLETPLVKAAQKAGAKIIPGSEMLLYQAMKQFELFTEISPNAEDIIKTRERLSKALENR
>Mature_313_residues
MHLTRNESKKLNLVCKIHKEKIEMKTKTNQSVKTFGIVGFPLSHSLSPLIHNSIYKDRNINASYLVFETQNLNVEKIQEF
RNSGILGLSVTIPHKETAFTLADKADDTSRIMKASNTLLIGPDSTYAYNTDGEGAYHSILEFSPESLKTGKVVILGSGGS
ARGIAFSLAVSGKIQNLLVCSRNEITAKEICLLVTKNSNVKAEPISQDVLLTRKEEISLVIHTTPLGMKGQSPGPYLPED
FFNSNMTLFDIVYNPLETPLVKAAQKAGAKIIPGSEMLLYQAMKQFELFTEISPNAEDIIKTRERLSKALENR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=267, Percent_Identity=28.0898876404494, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1789675, Length=284, Percent_Identity=29.2253521126761, Blast_Score=100, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=279, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 34631; Mature: 34631

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLTRNESKKLNLVCKIHKEKIEMKTKTNQSVKTFGIVGFPLSHSLSPLIHNSIYKDRNI
CCCCCCCCCEEEEEEEEEHHHHHHHHCCCCCEEEEEEEECCHHCCCCHHHHHHHHCCCCC
NASYLVFETQNLNVEKIQEFRNSGILGLSVTIPHKETAFTLADKADDTSRIMKASNTLLI
CEEEEEEEECCCCHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCCHHHHHHCCCEEEE
GPDSTYAYNTDGEGAYHSILEFSPESLKTGKVVILGSGGSARGIAFSLAVSGKIQNLLVC
CCCCCEEECCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEEE
SRNEITAKEICLLVTKNSNVKAEPISQDVLLTRKEEISLVIHTTPLGMKGQSPGPYLPED
CCCCCCHHHEEEEEECCCCCEECCCCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCHH
FFNSNMTLFDIVYNPLETPLVKAAQKAGAKIIPGSEMLLYQAMKQFELFTEISPNAEDII
HHCCCCEEEEEECCCCCHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHCCCCHHHHH
KTRERLSKALENR
HHHHHHHHHHHCC
>Mature Secondary Structure
MHLTRNESKKLNLVCKIHKEKIEMKTKTNQSVKTFGIVGFPLSHSLSPLIHNSIYKDRNI
CCCCCCCCCEEEEEEEEEHHHHHHHHCCCCCEEEEEEEECCHHCCCCHHHHHHHHCCCCC
NASYLVFETQNLNVEKIQEFRNSGILGLSVTIPHKETAFTLADKADDTSRIMKASNTLLI
CEEEEEEEECCCCHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCCHHHHHHCCCEEEE
GPDSTYAYNTDGEGAYHSILEFSPESLKTGKVVILGSGGSARGIAFSLAVSGKIQNLLVC
CCCCCEEECCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEEE
SRNEITAKEICLLVTKNSNVKAEPISQDVLLTRKEEISLVIHTTPLGMKGQSPGPYLPED
CCCCCCHHHEEEEEECCCCCEECCCCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCHH
FFNSNMTLFDIVYNPLETPLVKAAQKAGAKIIPGSEMLLYQAMKQFELFTEISPNAEDII
HHCCCCEEEEEECCCCCHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHCCCCHHHHH
KTRERLSKALENR
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA