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The map label for this gene is sglT

Identifier: 45658738

GI number: 45658738

Start: 3529726

End: 3531531

Strand: Reverse

Name: sglT

Synonym: LIC12908

Alternate gene names: 45658738

Gene position: 3531531-3529726 (Counterclockwise)

Preceding gene: 45658748

Following gene: 45658736

Centisome position: 82.57

GC content: 38.37

Gene sequence:

>1806_bases
ATGTTCAGTTTTATAGATTGGTTTTTTATATTTATGTATCTATTCTTTGCGTTTACAGCGGGAATATTACTTTCTCCAAA
AGCGGGTAAAAGTCTCGTTTCCTATTTTGTAGCCGATCGTAAACTACCTTGGTGGTGGCTCGGAACTTCGATGGTTGCGA
CCACGTTCGCCGCGGATACCCCTCTTGTAATTACCGGTTTTATCGCGGCTGACGGAATCTCGGCTAACTGGTTTTGGTGG
AGTTGGGCGATCGGTTATATGGCCATGACCGTTTTTTTTGCGGGTAAGTGGAGAAGGATGGAAGTTTTAACGGACGTTGA
GTTTGTAGAGCTACGTTATGGAGGCAAACCGGCAATTATACTTAGAATGGTCAAAGCATTCTATTTAAGTATATTAGTAA
ATTCGATTGTACTAGGATGGGTGTTTAAGGCGATGTCCAAAATTACTGGACCTTTCTTAGATTGGAAAGATTTACTCGGT
GCCGATCGGTTTTCGATTATACAAAACGTGTGGCCTTCTTTTTTAATATTTGATTCTTTGAATAATACGATTACTGTTTT
GATTTTATTTTTAGTGGTAGTCGTTTATAGCAGCATGGGAGGGATCCAAGGTGTGATCCTGACAGATCTTGTTCAATTTG
CTTTGGGAATGGGTGGAGCAATTTTGTTTGCGGTATATGCGGTTTCGAGTCAGGGAGGAATTTCCGGATTACTTTCAAAA
ATGGAAGAATTATATCCTGACAAACACAAATCGATTTTGAGTTTTTGGCCGGACTTTCAAGAAGCTTCATTATCAATTAA
TGTTTTTTTAATATTCATAAGTGTACAATGGTGGGCTCAGTATTATTCTGATGGTTCGGGGTATTTGGCTCAAAGAATAC
ACACCGCAAAAAATCCAAAAGAAGCAGAAAAGGGATCTCTTTGGTTTAACATAGCCAATTTTATGGTTCGCACCTGGCCT
TGGATATTAACTGCACTTGTAACGTTAGTTGTGTTTCCTTTGCACGATCCGACAAAATATTTTTCAGAAGGATGGATCGT
AGGCGGCGATCGTGAAATGGGATATCCGATTTTAATGAAATTGATATTACCCAATGGAATTTTGGGAATTGTATTTGCGA
GTTTGATGGCCGCTTTTATGTCTACGGCTGACACTCATATCAATTGGGGTGCGAGTTATCTTGTAAACGATTTTTATTTG
AGATTTGTACATCCAAAAGCGGACGATAAAACTTTGGTGAAAGCGAGTAGAATTGCAGTAGTTACTATGTCTATCATCGC
CATTTTGGTAGCCACTCAGATTCAATCTATCGCGAACGCTTGGAAATTTTTATTGGCATTTGCTTCCGGAATGGGATTAC
CTCAAATACTAAGATGGATTTGGTGGAGGACTAACGCTTGGACTGAACTTTCCGGAATGATCACCGCGTTGATCCTTTCT
ATGATTTTGTATCCTTCTTATCCAAATGTTCGATCGGAATATCTTTTATTTTGGGTTGCGATAGGTTCTGTTGCGGTTTC
GATCCTAGTTACGTTTTTAACCCCGCCGGTTCCACAAAACACGTTAGACGATTTTATAAAAAGAGTTGATCCTATCGGAT
TTTGGAAAGGAGAAGATAATAAAAAAAGACTCGAGGATTTTTATAAAAAAATCTTTCTTTGGCTTTTAGGAACGGTCGCT
TTATTTTTTGGAATGTTTTCTTTAGGGTATTTTTTCTTATTACAGTCTTGGCAAGGGTTCTTTTGTTTGTTTGGTTTTGT
GTTTTTAGGGATCTTGTATTGGAAAAAAGAATTTGGTAGAATTTGA

Upstream 100 bases:

>100_bases
GGTTTCGTTTTCAAGAAAGGTATTAAAACTGACGAAAGTTTTATCAGCATATAGGATTTCGTATTTAAACGAGTCTTGAT
TCTACCTTTAAGAAAAAAGT

Downstream 100 bases:

>100_bases
TAGATTCTAAATTATAGTAAAATAAAATATTATAATAAATTAATAATCAATATTTGTCATAAAATGTGTATAAACGGTGC
TATACATTTGGTTCTTGAAT

Product: sodium/glucose cotransport protein

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MFSFIDWFFIFMYLFFAFTAGILLSPKAGKSLVSYFVADRKLPWWWLGTSMVATTFAADTPLVITGFIAADGISANWFWW
SWAIGYMAMTVFFAGKWRRMEVLTDVEFVELRYGGKPAIILRMVKAFYLSILVNSIVLGWVFKAMSKITGPFLDWKDLLG
ADRFSIIQNVWPSFLIFDSLNNTITVLILFLVVVVYSSMGGIQGVILTDLVQFALGMGGAILFAVYAVSSQGGISGLLSK
MEELYPDKHKSILSFWPDFQEASLSINVFLIFISVQWWAQYYSDGSGYLAQRIHTAKNPKEAEKGSLWFNIANFMVRTWP
WILTALVTLVVFPLHDPTKYFSEGWIVGGDREMGYPILMKLILPNGILGIVFASLMAAFMSTADTHINWGASYLVNDFYL
RFVHPKADDKTLVKASRIAVVTMSIIAILVATQIQSIANAWKFLLAFASGMGLPQILRWIWWRTNAWTELSGMITALILS
MILYPSYPNVRSEYLLFWVAIGSVAVSILVTFLTPPVPQNTLDDFIKRVDPIGFWKGEDNKKRLEDFYKKIFLWLLGTVA
LFFGMFSLGYFFLLQSWQGFFCLFGFVFLGILYWKKEFGRI

Sequences:

>Translated_601_residues
MFSFIDWFFIFMYLFFAFTAGILLSPKAGKSLVSYFVADRKLPWWWLGTSMVATTFAADTPLVITGFIAADGISANWFWW
SWAIGYMAMTVFFAGKWRRMEVLTDVEFVELRYGGKPAIILRMVKAFYLSILVNSIVLGWVFKAMSKITGPFLDWKDLLG
ADRFSIIQNVWPSFLIFDSLNNTITVLILFLVVVVYSSMGGIQGVILTDLVQFALGMGGAILFAVYAVSSQGGISGLLSK
MEELYPDKHKSILSFWPDFQEASLSINVFLIFISVQWWAQYYSDGSGYLAQRIHTAKNPKEAEKGSLWFNIANFMVRTWP
WILTALVTLVVFPLHDPTKYFSEGWIVGGDREMGYPILMKLILPNGILGIVFASLMAAFMSTADTHINWGASYLVNDFYL
RFVHPKADDKTLVKASRIAVVTMSIIAILVATQIQSIANAWKFLLAFASGMGLPQILRWIWWRTNAWTELSGMITALILS
MILYPSYPNVRSEYLLFWVAIGSVAVSILVTFLTPPVPQNTLDDFIKRVDPIGFWKGEDNKKRLEDFYKKIFLWLLGTVA
LFFGMFSLGYFFLLQSWQGFFCLFGFVFLGILYWKKEFGRI
>Mature_601_residues
MFSFIDWFFIFMYLFFAFTAGILLSPKAGKSLVSYFVADRKLPWWWLGTSMVATTFAADTPLVITGFIAADGISANWFWW
SWAIGYMAMTVFFAGKWRRMEVLTDVEFVELRYGGKPAIILRMVKAFYLSILVNSIVLGWVFKAMSKITGPFLDWKDLLG
ADRFSIIQNVWPSFLIFDSLNNTITVLILFLVVVVYSSMGGIQGVILTDLVQFALGMGGAILFAVYAVSSQGGISGLLSK
MEELYPDKHKSILSFWPDFQEASLSINVFLIFISVQWWAQYYSDGSGYLAQRIHTAKNPKEAEKGSLWFNIANFMVRTWP
WILTALVTLVVFPLHDPTKYFSEGWIVGGDREMGYPILMKLILPNGILGIVFASLMAAFMSTADTHINWGASYLVNDFYL
RFVHPKADDKTLVKASRIAVVTMSIIAILVATQIQSIANAWKFLLAFASGMGLPQILRWIWWRTNAWTELSGMITALILS
MILYPSYPNVRSEYLLFWVAIGSVAVSILVTFLTPPVPQNTLDDFIKRVDPIGFWKGEDNKKRLEDFYKKIFLWLLGTVA
LFFGMFSLGYFFLLQSWQGFFCLFGFVFLGILYWKKEFGRI

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI14140236, Length=612, Percent_Identity=19.9346405228758, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI109659836, Length=611, Percent_Identity=20.6219312602291, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI109659839, Length=631, Percent_Identity=20.919175911252, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI206597483, Length=576, Percent_Identity=22.7430555555556, Blast_Score=67, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 68405; Mature: 68405

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSFIDWFFIFMYLFFAFTAGILLSPKAGKSLVSYFVADRKLPWWWLGTSMVATTFAADT
CCHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHCCCCCEEECCHHHHHHHHCCCC
PLVITGFIAADGISANWFWWSWAIGYMAMTVFFAGKWRRMEVLTDVEFVELRYGGKPAII
CEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCHHHH
LRMVKAFYLSILVNSIVLGWVFKAMSKITGPFLDWKDLLGADRFSIIQNVWPSFLIFDSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHCHHHEEHHCC
NNTITVLILFLVVVVYSSMGGIQGVILTDLVQFALGMGGAILFAVYAVSSQGGISGLLSK
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHH
MEELYPDKHKSILSFWPDFQEASLSINVFLIFISVQWWAQYYSDGSGYLAQRIHTAKNPK
HHHHCCCHHHHHHHHCCCHHHCCCEEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCC
EAEKGSLWFNIANFMVRTWPWILTALVTLVVFPLHDPTKYFSEGWIVGGDREMGYPILMK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEECCCCCCCHHHHHH
LILPNGILGIVFASLMAAFMSTADTHINWGASYLVNDFYLRFVHPKADDKTLVKASRIAV
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHH
VTMSIIAILVATQIQSIANAWKFLLAFASGMGLPQILRWIWWRTNAWTELSGMITALILS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
MILYPSYPNVRSEYLLFWVAIGSVAVSILVTFLTPPVPQNTLDDFIKRVDPIGFWKGEDN
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
KKRLEDFYKKIFLWLLGTVALFFGMFSLGYFFLLQSWQGFFCLFGFVFLGILYWKKEFGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
I
C
>Mature Secondary Structure
MFSFIDWFFIFMYLFFAFTAGILLSPKAGKSLVSYFVADRKLPWWWLGTSMVATTFAADT
CCHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHCCCCCEEECCHHHHHHHHCCCC
PLVITGFIAADGISANWFWWSWAIGYMAMTVFFAGKWRRMEVLTDVEFVELRYGGKPAII
CEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCHHHH
LRMVKAFYLSILVNSIVLGWVFKAMSKITGPFLDWKDLLGADRFSIIQNVWPSFLIFDSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHCHHHEEHHCC
NNTITVLILFLVVVVYSSMGGIQGVILTDLVQFALGMGGAILFAVYAVSSQGGISGLLSK
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHH
MEELYPDKHKSILSFWPDFQEASLSINVFLIFISVQWWAQYYSDGSGYLAQRIHTAKNPK
HHHHCCCHHHHHHHHCCCHHHCCCEEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCC
EAEKGSLWFNIANFMVRTWPWILTALVTLVVFPLHDPTKYFSEGWIVGGDREMGYPILMK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEECCCCCCCHHHHHH
LILPNGILGIVFASLMAAFMSTADTHINWGASYLVNDFYLRFVHPKADDKTLVKASRIAV
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHH
VTMSIIAILVATQIQSIANAWKFLLAFASGMGLPQILRWIWWRTNAWTELSGMITALILS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
MILYPSYPNVRSEYLLFWVAIGSVAVSILVTFLTPPVPQNTLDDFIKRVDPIGFWKGEDN
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
KKRLEDFYKKIFLWLLGTVALFFGMFSLGYFFLLQSWQGFFCLFGFVFLGILYWKKEFGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]