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The map label for this gene is secY

Identifier: 45658683

GI number: 45658683

Start: 3458869

End: 3460251

Strand: Reverse

Name: secY

Synonym: LIC12853

Alternate gene names: 45658683

Gene position: 3460251-3458869 (Counterclockwise)

Preceding gene: 45658684

Following gene: 45658682

Centisome position: 80.9

GC content: 38.32

Gene sequence:

>1383_bases
ATGCTGACAACATTTAAAAATATATTCAGAATTCCGGAGTTACGTCAGAAAATTATTTTTACTTTGAGTATGCTTCTGTT
GTTCCGTATGGGTACGCATATTACGATTCCAGGAATCAATCCGGTTGTGGTTGCAGGAATTGCGAATGATCCTTCTTCCG
AAGGTCTTCTCGGAATGGTAGATCTTTTTGCTGGCGGAGCCTTGTTGAAATTTTCCATTTTCGCGCTTGGAATCATGCCT
TATATTTCTTCTTCGATCGTAATGCAGCTTTTTATGGTCCTTGTTCCTGCCCTTCAAAAACTTCAAAAAGAAGGAGAAGA
AGGAAGAAAAAAAATCGGTCAATATACTAAGTATGGAACCGTAATTCTTTGTGCTATTCAATCTTTAGCAGTGATCCAAC
TCGCAAAGGGCTGGTCTACCGGCACGGAACTTGAGCCTGCGCGTTACCCGGGCTTAATCAATTCTTCTGTTGTTCCTTAT
TTTTATTTAATCGGAATCTTATCCATTACTACCGGAACCGTTCTTCTCATTTGGTTAGGAGAACAGATCACCGAAAGAGG
AATTGGTAATGGAATTTCTCTTTTGATCTTCGCTGGAATTATCGGAAGACTGCCTGAGTCTATGGTTCAACTTTTCTCTA
CCGATACGATGGATGCGTTGAATGTTCTTATCCTTTTGATTCTTTTTATTCTTCTCATTTCCTTGACGGTGTTATTAACG
CAAGGTGTGAGAAAGGTTCCTCTGCAGTACGGAAAACAAATGGTCGGAAGAAAAATGGTTCAGGCCAAGAGTCAATCTAT
TCCTTTCAAAGTAAACGGCGCGAACGTGATGCCGATCATTTTTGCTTCGTCTTTGATTTTATTTCCTCAGACGATTATTC
AATGGTTATCTAATAGTAGTCAAGAATGGGCTGGATGGGCAGTGATTATGGATTTTTTTAATCCATTCTCTCAGATTTGG
TATCATGCGTTATTTTATTTCGTAATTTATACCGCTTTAATTGTATTCTTTGCTTACTTTTATACAGCGATTCAGTTTAA
TCCTGCAGAATTGGCTGAGAATTTGAAAAAATACGGTGGGTTCATTCCAGGAATTCGTCCGGGTTCTCACACAAAAGAAT
ACATTGAAAAAGTGTTAAATAGAATCACTCTTCCCGGAGCTATGTTTCTTGCAGGTTTGGCATTAGCACCTTATATTATT
ATAAAATTCTTAGATTTGAGCTCTAACTCCGGCGGTGGATCTTTGGTTTATACATTCGGTGGAACTTCTCTTCTAATTAT
GGTAGGGGTTGCACTCGAGACTTTAAAACAAATTGAGTCTCAACTTTTAATGAGAAATTATGAAGGCTTCATGAAGAAGT
CTAAAATTAAGGGACGGTCTTAA

Upstream 100 bases:

>100_bases
CGGCCAAAGAAAAAATTGAGAAAGCGGGCGGATCTATCAAATTACGCGCCGAACTTAAACTGGCCACGTCAGAAACTAAA
AAATAAAAGCAAGAGTATCC

Downstream 100 bases:

>100_bases
TTTTTCCGTGAAGAATATTATCTTCATGGGGCCTCCTGGGGCTGGAAAAGGTACACAAGCAAAGATTCTTTGTGAGCGCC
TTTCTATTCCTCAGATTTCT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MLTTFKNIFRIPELRQKIIFTLSMLLLFRMGTHITIPGINPVVVAGIANDPSSEGLLGMVDLFAGGALLKFSIFALGIMP
YISSSIVMQLFMVLVPALQKLQKEGEEGRKKIGQYTKYGTVILCAIQSLAVIQLAKGWSTGTELEPARYPGLINSSVVPY
FYLIGILSITTGTVLLIWLGEQITERGIGNGISLLIFAGIIGRLPESMVQLFSTDTMDALNVLILLILFILLISLTVLLT
QGVRKVPLQYGKQMVGRKMVQAKSQSIPFKVNGANVMPIIFASSLILFPQTIIQWLSNSSQEWAGWAVIMDFFNPFSQIW
YHALFYFVIYTALIVFFAYFYTAIQFNPAELAENLKKYGGFIPGIRPGSHTKEYIEKVLNRITLPGAMFLAGLALAPYII
IKFLDLSSNSGGGSLVYTFGGTSLLIMVGVALETLKQIESQLLMRNYEGFMKKSKIKGRS

Sequences:

>Translated_460_residues
MLTTFKNIFRIPELRQKIIFTLSMLLLFRMGTHITIPGINPVVVAGIANDPSSEGLLGMVDLFAGGALLKFSIFALGIMP
YISSSIVMQLFMVLVPALQKLQKEGEEGRKKIGQYTKYGTVILCAIQSLAVIQLAKGWSTGTELEPARYPGLINSSVVPY
FYLIGILSITTGTVLLIWLGEQITERGIGNGISLLIFAGIIGRLPESMVQLFSTDTMDALNVLILLILFILLISLTVLLT
QGVRKVPLQYGKQMVGRKMVQAKSQSIPFKVNGANVMPIIFASSLILFPQTIIQWLSNSSQEWAGWAVIMDFFNPFSQIW
YHALFYFVIYTALIVFFAYFYTAIQFNPAELAENLKKYGGFIPGIRPGSHTKEYIEKVLNRITLPGAMFLAGLALAPYII
IKFLDLSSNSGGGSLVYTFGGTSLLIMVGVALETLKQIESQLLMRNYEGFMKKSKIKGRS
>Mature_460_residues
MLTTFKNIFRIPELRQKIIFTLSMLLLFRMGTHITIPGINPVVVAGIANDPSSEGLLGMVDLFAGGALLKFSIFALGIMP
YISSSIVMQLFMVLVPALQKLQKEGEEGRKKIGQYTKYGTVILCAIQSLAVIQLAKGWSTGTELEPARYPGLINSSVVPY
FYLIGILSITTGTVLLIWLGEQITERGIGNGISLLIFAGIIGRLPESMVQLFSTDTMDALNVLILLILFILLISLTVLLT
QGVRKVPLQYGKQMVGRKMVQAKSQSIPFKVNGANVMPIIFASSLILFPQTIIQWLSNSSQEWAGWAVIMDFFNPFSQIW
YHALFYFVIYTALIVFFAYFYTAIQFNPAELAENLKKYGGFIPGIRPGSHTKEYIEKVLNRITLPGAMFLAGLALAPYII
IKFLDLSSNSGGGSLVYTFGGTSLLIMVGVALETLKQIESQLLMRNYEGFMKKSKIKGRS

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=449, Percent_Identity=40.7572383073497, Blast_Score=301, Evalue=9e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 50852; Mature: 50852

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS00018 EF_HAND_1 ; PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTFKNIFRIPELRQKIIFTLSMLLLFRMGTHITIPGINPVVVAGIANDPSSEGLLGMV
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCCCCHHHHH
DLFAGGALLKFSIFALGIMPYISSSIVMQLFMVLVPALQKLQKEGEEGRKKIGQYTKYGT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILCAIQSLAVIQLAKGWSTGTELEPARYPGLINSSVVPYFYLIGILSITTGTVLLIWLG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEHHH
EQITERGIGNGISLLIFAGIIGRLPESMVQLFSTDTMDALNVLILLILFILLISLTVLLT
HHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QGVRKVPLQYGKQMVGRKMVQAKSQSIPFKVNGANVMPIIFASSLILFPQTIIQWLSNSS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
QEWAGWAVIMDFFNPFSQIWYHALFYFVIYTALIVFFAYFYTAIQFNPAELAENLKKYGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
FIPGIRPGSHTKEYIEKVLNRITLPGAMFLAGLALAPYIIIKFLDLSSNSGGGSLVYTFG
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
GTSLLIMVGVALETLKQIESQLLMRNYEGFMKKSKIKGRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLTTFKNIFRIPELRQKIIFTLSMLLLFRMGTHITIPGINPVVVAGIANDPSSEGLLGMV
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCCCCHHHHH
DLFAGGALLKFSIFALGIMPYISSSIVMQLFMVLVPALQKLQKEGEEGRKKIGQYTKYGT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILCAIQSLAVIQLAKGWSTGTELEPARYPGLINSSVVPYFYLIGILSITTGTVLLIWLG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEHHH
EQITERGIGNGISLLIFAGIIGRLPESMVQLFSTDTMDALNVLILLILFILLISLTVLLT
HHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QGVRKVPLQYGKQMVGRKMVQAKSQSIPFKVNGANVMPIIFASSLILFPQTIIQWLSNSS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
QEWAGWAVIMDFFNPFSQIWYHALFYFVIYTALIVFFAYFYTAIQFNPAELAENLKKYGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
FIPGIRPGSHTKEYIEKVLNRITLPGAMFLAGLALAPYIIIKFLDLSSNSGGGSLVYTFG
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
GTSLLIMVGVALETLKQIESQLLMRNYEGFMKKSKIKGRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10542330 [H]