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The map label for this gene is ywfG

Identifier: 45658671

GI number: 45658671

Start: 3444916

End: 3446142

Strand: Direct

Name: ywfG

Synonym: LIC12841

Alternate gene names: 45658671

Gene position: 3444916-3446142 (Clockwise)

Preceding gene: 45658670

Following gene: 45658672

Centisome position: 80.54

GC content: 40.18

Gene sequence:

>1227_bases
ATGGCGAACATCAATGAAAATTATTTAAAACTAAAAGCGGGATATTTATTTCCAGAAATTTCGAAACGAGTCAAGATTTA
CTCCGAAAAAAATCCTTCGGCAAAAATCATTCGACTGGGTATCGGAGATGTGACTCTTCCGATCGTTCCTTCGGTTGTGG
ATGCAATGGTAGAGGCTTCTAAAGAGATGGGAACCGTTGGGGGTTTTCACGGTTATGGTCCCGAACAAGGATATTCATTT
TTGCTAAAGTCGATTGCGGATCATGACTACGGTTCACTTGGAATCAAAATAGACGAAAGCGAAATATTTGTCTCAGACGG
ATCTAAATGCGATTGTGGTAATATTCAAGAAATCTTTTCTACGGATTCTAAAATCGCGGTCGCAGATCCGGTTTATCCAG
TTTACGTAGATACAAACGTAATGGCGGGTAGAACCGGCGAAATCGGTCCTGACGGCAGATACTCCAATTTGATCTATATG
CCCGCCACGAAAGAAAACGGTTTTCAACCGGAAATTCCGAAAGAAAAAGCGGACATCGTTTATCTTTGTTATCCGAACAA
TCCTACCGGAACCGTAACCACAAAAGAATCCTTAAAAGCTTGGGTAGAATATGCTAAAAAAAATAACTCTATCATTCTTT
ATGATTCCGCTTACGAAGCTTTTATCAGCGAACCTGGAGTTCCTCGTTCTATCTATGAAGTAGAAGGCGCGAAGGAAGTA
GCGATCGAATTCCGTTCTTTTTCAAAAACTGCGGGTTTTACAGGTTTAAGATGTGCTTATATAGTTATCCCTAAAGAACT
CAAAGGAAGAACACGTTCCGGCGAAGAAGTCAGTCTCAATTCTCTTTGGAATAGAAGACATACCACTAAGTTCAACGGAG
TTTCTTATGTGACTCAAAAAGGTGCAGAAGCTTGTTATTCCCCTCAAGGAAAAAAAGAAATCCAAACTTCCATCGCTTAT
TATATGGCAAACGCTTCTAAAATTCGAGATGGTTTAAAAAAAGCTGGTTATGAAGTTTTCGGCGGGGTTAACGCTCCTTA
CATCTGGTTAAAAACTTCGGATAATCTTTCTTCTTGGGATTTTTTTGATAAACTTTTAAATAAAGCTCAAGTGGTCGGAA
CTCCGGGCTCCGGTTTTGGTCCAGCGGGCGAAGGTTATTTCCGTCTCAGTGCTTTTGGTAAAAAAGAAGACGTAGAAGAA
GCAATCGCAAGGATTACATCTCTTTAA

Upstream 100 bases:

>100_bases
GGATATTATTGTTGGCACTTAGGAGAGGAAGACCTTCTTTACGAACACGGCTACGAAGAAGGTTTTGCCGGAAGAAAACA
AATCGACAAGGATCAAAAAG

Downstream 100 bases:

>100_bases
AAGTAGGAGTTCCCACATTTTAGAAACAATTTTACAGTAAAGTTTTGTCGTGCAGTAGTTCCCACAAATTAAGTCGCATT
TGGCAATTTACGAACTTTCA

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MANINENYLKLKAGYLFPEISKRVKIYSEKNPSAKIIRLGIGDVTLPIVPSVVDAMVEASKEMGTVGGFHGYGPEQGYSF
LLKSIADHDYGSLGIKIDESEIFVSDGSKCDCGNIQEIFSTDSKIAVADPVYPVYVDTNVMAGRTGEIGPDGRYSNLIYM
PATKENGFQPEIPKEKADIVYLCYPNNPTGTVTTKESLKAWVEYAKKNNSIILYDSAYEAFISEPGVPRSIYEVEGAKEV
AIEFRSFSKTAGFTGLRCAYIVIPKELKGRTRSGEEVSLNSLWNRRHTTKFNGVSYVTQKGAEACYSPQGKKEIQTSIAY
YMANASKIRDGLKKAGYEVFGGVNAPYIWLKTSDNLSSWDFFDKLLNKAQVVGTPGSGFGPAGEGYFRLSAFGKKEDVEE
AIARITSL

Sequences:

>Translated_408_residues
MANINENYLKLKAGYLFPEISKRVKIYSEKNPSAKIIRLGIGDVTLPIVPSVVDAMVEASKEMGTVGGFHGYGPEQGYSF
LLKSIADHDYGSLGIKIDESEIFVSDGSKCDCGNIQEIFSTDSKIAVADPVYPVYVDTNVMAGRTGEIGPDGRYSNLIYM
PATKENGFQPEIPKEKADIVYLCYPNNPTGTVTTKESLKAWVEYAKKNNSIILYDSAYEAFISEPGVPRSIYEVEGAKEV
AIEFRSFSKTAGFTGLRCAYIVIPKELKGRTRSGEEVSLNSLWNRRHTTKFNGVSYVTQKGAEACYSPQGKKEIQTSIAY
YMANASKIRDGLKKAGYEVFGGVNAPYIWLKTSDNLSSWDFFDKLLNKAQVVGTPGSGFGPAGEGYFRLSAFGKKEDVEE
AIARITSL
>Mature_407_residues
ANINENYLKLKAGYLFPEISKRVKIYSEKNPSAKIIRLGIGDVTLPIVPSVVDAMVEASKEMGTVGGFHGYGPEQGYSFL
LKSIADHDYGSLGIKIDESEIFVSDGSKCDCGNIQEIFSTDSKIAVADPVYPVYVDTNVMAGRTGEIGPDGRYSNLIYMP
ATKENGFQPEIPKEKADIVYLCYPNNPTGTVTTKESLKAWVEYAKKNNSIILYDSAYEAFISEPGVPRSIYEVEGAKEVA
IEFRSFSKTAGFTGLRCAYIVIPKELKGRTRSGEEVSLNSLWNRRHTTKFNGVSYVTQKGAEACYSPQGKKEIQTSIAYY
MANASKIRDGLKKAGYEVFGGVNAPYIWLKTSDNLSSWDFFDKLLNKAQVVGTPGSGFGPAGEGYFRLSAFGKKEDVEEA
IARITSL

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=403, Percent_Identity=24.317617866005, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44819; Mature: 44688

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANINENYLKLKAGYLFPEISKRVKIYSEKNPSAKIIRLGIGDVTLPIVPSVVDAMVEAS
CCCCCCCEEEEEECCCCHHHHHHEEEEECCCCCCEEEEEECCCEEHHHHHHHHHHHHHHH
KEMGTVGGFHGYGPEQGYSFLLKSIADHDYGSLGIKIDESEIFVSDGSKCDCGNIQEIFS
HHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCCCCCCHHHHHC
TDSKIAVADPVYPVYVDTNVMAGRTGEIGPDGRYSNLIYMPATKENGFQPEIPKEKADIV
CCCCEEEECCCEEEEEECCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEE
YLCYPNNPTGTVTTKESLKAWVEYAKKNNSIILYDSAYEAFISEPGVPRSIYEVEGAKEV
EEEECCCCCCCEEEHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCHHEECCCCHHH
AIEFRSFSKTAGFTGLRCAYIVIPKELKGRTRSGEEVSLNSLWNRRHTTKFNGVSYVTQK
HHHHHHHHCCCCCCCCEEEEEEEEHHHCCCCCCCCEEEHHHHHCCCCCCCCCCCHHHHHH
GAEACYSPQGKKEIQTSIAYYMANASKIRDGLKKAGYEVFGGVNAPYIWLKTSDNLSSWD
CHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCHHEECCCCCCEEEEEECCCCCHHH
FFDKLLNKAQVVGTPGSGFGPAGEGYFRLSAFGKKEDVEEAIARITSL
HHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANINENYLKLKAGYLFPEISKRVKIYSEKNPSAKIIRLGIGDVTLPIVPSVVDAMVEAS
CCCCCCEEEEEECCCCHHHHHHEEEEECCCCCCEEEEEECCCEEHHHHHHHHHHHHHHH
KEMGTVGGFHGYGPEQGYSFLLKSIADHDYGSLGIKIDESEIFVSDGSKCDCGNIQEIFS
HHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCCCCCCHHHHHC
TDSKIAVADPVYPVYVDTNVMAGRTGEIGPDGRYSNLIYMPATKENGFQPEIPKEKADIV
CCCCEEEECCCEEEEEECCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEE
YLCYPNNPTGTVTTKESLKAWVEYAKKNNSIILYDSAYEAFISEPGVPRSIYEVEGAKEV
EEEECCCCCCCEEEHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCHHEECCCCHHH
AIEFRSFSKTAGFTGLRCAYIVIPKELKGRTRSGEEVSLNSLWNRRHTTKFNGVSYVTQK
HHHHHHHHCCCCCCCCEEEEEEEEHHHCCCCCCCCEEEHHHHHCCCCCCCCCCCHHHHHH
GAEACYSPQGKKEIQTSIAYYMANASKIRDGLKKAGYEVFGGVNAPYIWLKTSDNLSSWD
CHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCHHEECCCCCCEEEEEECCCCCHHH
FFDKLLNKAQVVGTPGSGFGPAGEGYFRLSAFGKKEDVEEAIARITSL
HHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA