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The map label for this gene is mgsA

Identifier: 45658567

GI number: 45658567

Start: 3329123

End: 3329569

Strand: Reverse

Name: mgsA

Synonym: LIC12733

Alternate gene names: 45658567

Gene position: 3329569-3329123 (Counterclockwise)

Preceding gene: 45658570

Following gene: 45658566

Centisome position: 77.84

GC content: 37.36

Gene sequence:

>447_bases
ATGAAAGAAGTTTCCGTTCCGGCAATCAAAAGAATCGTATTGATTGCCCATGATAATCGTAAAGAAGATTTAGTAAACTG
GGTAAAAACTCACAGAGAAATCCTTTCAAAACATCAGCTATATGGAACTGGAACGACTGGAAAATTGATAAGCGAAGAAA
CCGAACTTCCGGTTTACAGATTTCTTTCTGGGCCGTTGGGAGGAGATCAGCAAATTGGTGCTAAGATTGCTGAAGGAGAT
TTAGATATAGTAATTTTTTTCTGGGATCCACTAACAGCTCAACCCCATGATCCGGATGTAAAAGCTTTGCTTAGAATTGC
GGTTTTATACAACGTTCCTATGGCTTGTAACCGATCCACTGCCGATTATATGATCAGTTCTCCTCAATTTACAAAAACTT
ATAAAAAGATCCTTTTGAGTTACAATACTAAAGTAAAAAAGGACTGA

Upstream 100 bases:

>100_bases
GAATCGATTTGAAAAAAAATATTTTAAGTCAATTTAGGATTGGTTTGAAATTTGCGTCATCAAAAAATTAGATTCAAAAT
AAACGAGAAAGAGTAATAAA

Downstream 100 bases:

>100_bases
TTAAAATAAGATTTATATTCAAAAGAAAATTTGAATATAGTAGGTTTTTAAAAAAAACAGATGCAGAATTCTAAAATGTT
TATATTTACGGTATCGGTTA

Product: methylglyoxal synthase

Products: NA

Alternate protein names: MGS

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKEVSVPAIKRIVLIAHDNRKEDLVNWVKTHREILSKHQLYGTGTTGKLISEETELPVYRFLSGPLGGDQQIGAKIAEGD
LDIVIFFWDPLTAQPHDPDVKALLRIAVLYNVPMACNRSTADYMISSPQFTKTYKKILLSYNTKVKKD

Sequences:

>Translated_148_residues
MKEVSVPAIKRIVLIAHDNRKEDLVNWVKTHREILSKHQLYGTGTTGKLISEETELPVYRFLSGPLGGDQQIGAKIAEGD
LDIVIFFWDPLTAQPHDPDVKALLRIAVLYNVPMACNRSTADYMISSPQFTKTYKKILLSYNTKVKKD
>Mature_148_residues
MKEVSVPAIKRIVLIAHDNRKEDLVNWVKTHREILSKHQLYGTGTTGKLISEETELPVYRFLSGPLGGDQQIGAKIAEGD
LDIVIFFWDPLTAQPHDPDVKALLRIAVLYNVPMACNRSTADYMISSPQFTKTYKKILLSYNTKVKKD

Specific function: Unknown

COG id: COG1803

COG function: function code G; Methylglyoxal synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methylglyoxal synthase family

Homologues:

Organism=Escherichia coli, GI87081809, Length=137, Percent_Identity=54.014598540146, Blast_Score=166, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MGSA_LEPIC (Q72NU6)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_002653.1
- ProteinModelPortal:   Q72NU6
- SMR:   Q72NU6
- GeneID:   2770986
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC12733
- HOGENOM:   HBG298005
- OMA:   EPQPHDP
- ProtClustDB:   PRK05234
- BioCyc:   LINT267671:LIC_12733-MONOMER
- HAMAP:   MF_00549
- InterPro:   IPR004363
- InterPro:   IPR018148
- InterPro:   IPR011607
- Gene3D:   G3DSA:3.40.50.1380
- PIRSF:   PIRSF006614
- SMART:   SM00851
- TIGRFAMs:   TIGR00160

Pfam domain/function: PF02142 MGS; SSF52335 MGS-like_dom

EC number: =4.2.3.3

Molecular weight: Translated: 16728; Mature: 16728

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS01335 METHYLGLYOXAL_SYNTH

Important sites: ACT_SITE 69-69

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVSVPAIKRIVLIAHDNRKEDLVNWVKTHREILSKHQLYGTGTTGKLISEETELPVYR
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHH
FLSGPLGGDQQIGAKIAEGDLDIVIFFWDPLTAQPHDPDVKALLRIAVLYNVPMACNRST
HHCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
ADYMISSPQFTKTYKKILLSYNTKVKKD
CCEEECCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKEVSVPAIKRIVLIAHDNRKEDLVNWVKTHREILSKHQLYGTGTTGKLISEETELPVYR
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHH
FLSGPLGGDQQIGAKIAEGDLDIVIFFWDPLTAQPHDPDVKALLRIAVLYNVPMACNRST
HHCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
ADYMISSPQFTKTYKKILLSYNTKVKKD
CCEEECCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA