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The map label for this gene is yhdY [H]

Identifier: 45658507

GI number: 45658507

Start: 3234020

End: 3235030

Strand: Direct

Name: yhdY [H]

Synonym: LIC12671

Alternate gene names: 45658507

Gene position: 3234020-3235030 (Clockwise)

Preceding gene: 45658502

Following gene: 45658508

Centisome position: 75.61

GC content: 34.03

Gene sequence:

>1011_bases
ATGAATTGGAACGAAGTTCAAGACTGGTTCTCTAAAGACTTTCTTTGGGAATTAGGAAAAGCGACCGGAGTTTTTCTTTT
TGTATTGTTTTTTGGCTATCTATTAAGCGACAGAATCAGTCCCAAATTGTTTGGAGTTTTTTTCGGAAATAAAATTCCAA
CTTCCCATCCGATTTACAAAGCGGGAAGAAAAATCATCCGTTTATTTTTTTTACTACTTTCTTCTTTTTTATTTCTTAAA
TTTTTAAAACTCACTTCGGTAGAATCCGTTTTTTTAGGTTTTAAAATTCTTTCGATCGTACTTTGTACAATTTCACTCTC
TCATCTTTTTTCGGCAGTATTCGAAACCAAAACAGAAGGAATGGTTTCTTCTGCTTCTATCATAGGTAATGCGATCCGGA
TCATATTATTTACAGTTTGTATTCTATTGATTCTTCAATCTTTAGGAATTTCAATCGTTCCCATATTAGGAGCATTGGGA
GTAGGAGGTCTTGCAGTCGCTCTCGGTTTACAACCTACACTTTCAAATTTATTTTCCGGTTTAGGAATCCTTCTCGGAAA
ACAACTTAAAAGAGGAGACTACGTTCGAATGCAGGGAGAAGGATTAGAAGGTTACGTTCAAGACATCACTTGGAGAAGTA
CTACAATTCGAAAACGTAACGATAGTGTAATCGTAGTTCCAAACTCTGTGATGGCTTCCTCTGTAGTCACTACTTTAGAA
TTATCTAAAAAATGTTTTTCGATTCCAATCGAAGCAAGTATAAATTCTCAAACCGATTTGGAAAAAGTAGAGTCACTCGC
CATAAACATAGGAAATGAAGTCTTAAAAAAGTTTTATCCATCCGATTCAATCCGAGAAATTTCTTTCTCTTATCAAAAAT
TTGGACCTAATTCGGTAGGATTCCAAATGGATTTACCTTGTTTAGAATTTTCAGATCAATTTTTGATTCGACACGAATTT
ATCAAACAACTACATTCTAATTTTCAAAAAGAAGGAATCGAGTTTAAGTGA

Upstream 100 bases:

>100_bases
AATAGACACGATATAGACTTGAAATCCTTAAACCTTACATCAAAATGAAATCAAACGATTTGATCTTGCACGATTAATAT
TTTAAATAAAAAATGTTCTC

Downstream 100 bases:

>100_bases
TGATATACTTTATTCTCTGGCTGGTTTTGAAAAGAAAGGAACTACTCTATGTTTTACAGAATATTCTACTATTGGAATGT
ATTAAGTATTGATATAGTAT

Product: small conductance mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNWNEVQDWFSKDFLWELGKATGVFLFVLFFGYLLSDRISPKLFGVFFGNKIPTSHPIYKAGRKIIRLFFLLLSSFLFLK
FLKLTSVESVFLGFKILSIVLCTISLSHLFSAVFETKTEGMVSSASIIGNAIRIILFTVCILLILQSLGISIVPILGALG
VGGLAVALGLQPTLSNLFSGLGILLGKQLKRGDYVRMQGEGLEGYVQDITWRSTTIRKRNDSVIVVPNSVMASSVVTTLE
LSKKCFSIPIEASINSQTDLEKVESLAINIGNEVLKKFYPSDSIREISFSYQKFGPNSVGFQMDLPCLEFSDQFLIRHEF
IKQLHSNFQKEGIEFK

Sequences:

>Translated_336_residues
MNWNEVQDWFSKDFLWELGKATGVFLFVLFFGYLLSDRISPKLFGVFFGNKIPTSHPIYKAGRKIIRLFFLLLSSFLFLK
FLKLTSVESVFLGFKILSIVLCTISLSHLFSAVFETKTEGMVSSASIIGNAIRIILFTVCILLILQSLGISIVPILGALG
VGGLAVALGLQPTLSNLFSGLGILLGKQLKRGDYVRMQGEGLEGYVQDITWRSTTIRKRNDSVIVVPNSVMASSVVTTLE
LSKKCFSIPIEASINSQTDLEKVESLAINIGNEVLKKFYPSDSIREISFSYQKFGPNSVGFQMDLPCLEFSDQFLIRHEF
IKQLHSNFQKEGIEFK
>Mature_336_residues
MNWNEVQDWFSKDFLWELGKATGVFLFVLFFGYLLSDRISPKLFGVFFGNKIPTSHPIYKAGRKIIRLFFLLLSSFLFLK
FLKLTSVESVFLGFKILSIVLCTISLSHLFSAVFETKTEGMVSSASIIGNAIRIILFTVCILLILQSLGISIVPILGALG
VGGLAVALGLQPTLSNLFSGLGILLGKQLKRGDYVRMQGEGLEGYVQDITWRSTTIRKRNDSVIVVPNSVMASSVVTTLE
LSKKCFSIPIEASINSQTDLEKVESLAINIGNEVLKKFYPSDSIREISFSYQKFGPNSVGFQMDLPCLEFSDQFLIRHEF
IKQLHSNFQKEGIEFK

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1787591, Length=112, Percent_Identity=34.8214285714286, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789291, Length=208, Percent_Identity=25.4807692307692, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 37558; Mature: 37558

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWNEVQDWFSKDFLWELGKATGVFLFVLFFGYLLSDRISPKLFGVFFGNKIPTSHPIYK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCHHH
AGRKIIRLFFLLLSSFLFLKFLKLTSVESVFLGFKILSIVLCTISLSHLFSAVFETKTEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MVSSASIIGNAIRIILFTVCILLILQSLGISIVPILGALGVGGLAVALGLQPTLSNLFSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHH
LGILLGKQLKRGDYVRMQGEGLEGYVQDITWRSTTIRKRNDSVIVVPNSVMASSVVTTLE
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHHEEEECCCCEEEECCHHHHHHHHHHHH
LSKKCFSIPIEASINSQTDLEKVESLAINIGNEVLKKFYPSDSIREISFSYQKFGPNSVG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
FQMDLPCLEFSDQFLIRHEFIKQLHSNFQKEGIEFK
EEECCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNWNEVQDWFSKDFLWELGKATGVFLFVLFFGYLLSDRISPKLFGVFFGNKIPTSHPIYK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCHHH
AGRKIIRLFFLLLSSFLFLKFLKLTSVESVFLGFKILSIVLCTISLSHLFSAVFETKTEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MVSSASIIGNAIRIILFTVCILLILQSLGISIVPILGALGVGGLAVALGLQPTLSNLFSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHH
LGILLGKQLKRGDYVRMQGEGLEGYVQDITWRSTTIRKRNDSVIVVPNSVMASSVVTTLE
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCHHEEEECCCCEEEECCHHHHHHHHHHHH
LSKKCFSIPIEASINSQTDLEKVESLAINIGNEVLKKFYPSDSIREISFSYQKFGPNSVG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
FQMDLPCLEFSDQFLIRHEFIKQLHSNFQKEGIEFK
EEECCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]