| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is mrcA [H]
Identifier: 45658457
GI number: 45658457
Start: 3169681
End: 3172164
Strand: Direct
Name: mrcA [H]
Synonym: LIC12620
Alternate gene names: 45658457
Gene position: 3169681-3172164 (Clockwise)
Preceding gene: 45658456
Following gene: 45658458
Centisome position: 74.11
GC content: 41.51
Gene sequence:
>2484_bases ATGAAACAAGAACCAGTCAGCTATCTTTTCCGTTTTTTCGTCATTCATTTCCGGGATAAAATTCTATCTAGAGTTTTCAA TTCAGAAAACCCACTAAAACAGCTAGTCAAACTTTGTTCCGTCCTATTATTTTTAAACGGATTTCTATTCGTATTTTCCA TCAAGGATTTATGGAGAGTTCCAGAATCCAATCAATATGAAAAACCGTCCGTATTATACGGATTAGGCGAAAAAAACGAA TACGAACCAATCGCAGAATTTTATCGTTTTTCAAGGGTCGTTTTGAACATCAAAGAACTACCGCCAGAAGCGGACGGTAA ACCGAACAAACTCATCCGAAGTTTTGTTTCTACCGAAGACAATAATTTTTATTCTCATTGGGGATTGGATCTACGCGGAA TCTTTAGGGCGTTTATGGTAAATATACTCGCGGGAAGGATCAAAGAAGGAGCCTCGACGATCACCCAACAAGTAGCAAGA CTTAGATTCTTAAATACGGAACGTTCTTTTCTTCGAAAAGCAAGAGAAGCCTGGCTCGCTCTACTTTTAGAAGTAGTTTT TGATAAAGACACTCTGATGGAAATTTATCTCAATGAAATTCCACTCGGACACGGAACGATCGGAGTAGGAGCCGCCGCTA GATTTTATTTTAGAAAAGACGTAAAAGATTTAACCTGGGGAGAATCCGCGCTGTTAGCGAGCCTTACCACAAGGCCCACC GAATTTTCTCCCTTGGTCAATCCAAATTCATCCAGTGCCAAAGTCAGAGTTGTATTTAAGAAATTTGTAGAGAATGGAAT TTTAGACGTCAAAACCGCGGAAAAAGAATACGAAAGCTTTTCAGAATATTATATTACTCTAAATCGTTCCCCAAACGATT CCGCGTTTGGAGATAGACTCAATCGTTTTCCATACTTTACAGAATACGTTCGTAAAAACCTAACACGTTATATTCCAAAA TCCACACTTTATAGTGGCGGTCTCAAGATCTATTCCACCTTGAACATACAACACCAAACACAGGCAGAAAAAGCATTGTA TGCAGGACTCAAAGCGCAAACTGCATTGTCCAATCAAAGAACATTCACAAAAATAGATGCATTTGATGACGCCTACGGAG AAATCTACGATCTGTTATCGATGTTAAACGACATCCCGGATTTTAAATTTAAAATTTCCAGATCAGCGAGAACCTTCAAC CGCGCCTGGCAAGAAGACTTAAGAGACGAACTCAGCGCTCTCAATTTATTGAGTGGAACCGAAAGTTTAGGAGAGACAAT CGATTGGAATTACAAAAGCCAACAAACGGAAGACTTTCTTTTACCAGTCGAAGGGGCTTTGATTTCTATGAGACCAGATA CCGGATATATAACCGCAGTGGTAGGAGGTTCCGGATTTCGTTCGGACAATCAGCAGATCCGAGCCTTTCAAGCTTATCGT CAACCAGGCTCCGCGTTCAAACCTATCATATACGCTGCAGCAATGGAATACTTCAATGAACATCCAGATCCTAAAAAAAA TGTAACCGCTGCATCCCTTTTTTCGGATTCCCCTTTGCAATACGTATTAGAAGACGGTGATGAATGGAATCCATCTAATT ATACGGGAGAATATTCAGGATTTATAAAATTGCGAGAAGCCTTAGAACTTTCCAGAAACAGCGTCGCCGTCCGAGTGTTA GAGCATACAGGGATCAGCAACTTGATGCCCTACTTAGAAAAAATTCTTCAGATAGAAAACAGACCCATCCCAAAAAATTA CTCTATATCTTTGGGAACTTTTGAAGTATCACCTTACGAATTAGCGCGTGCCTATGCGGTGATCGCATCCGGAGGCAAAC AAGTATTTCCGCTCAGCGTTCTTTATGTAGAAGACGGGTCCGGCAAAGTGATCAAGGATTTTAGAGAGGAAGCAAACAAA CAAGAAAAGAAACAAATTCTTTCTCCGGCGGTTTGTTTTATTCTTACTTCCATGATGGAAGACGTAATCAAAAAAGGAAC CGGAACTGGTGCGGCCTCGTATGGGCTCAGTCGTCCTGCAGCGGGTAAAACTGGAACCACGAATAACTTTAGAGACGCAT GGTTTGCCGGTTATTCTTCCGAGTTAGTCAGCGTGGTTTGGTTAGGTTACGACACTGGAACCTTATCGATGGGAAAAGGG ATGTCGGGCGGAGTAGTAGCGGCTCCCATTTGGGGAAGGTTTATGTCCAACGCACTTTCCAGAGAAAAATCAAAGCCGTT TCACTTTGGAGAAACGGGTGTAGTTCGCAAACAAATCTGCTCCATTTCTGGAAAACTTCCGGGCTCTCATTGTCATCAAA CCGAAGAAGAATATTTTACTAAAGAAACTGTACCAAAAGAAGTTTGTGACGATCATCGTGGAGCCGGTTTTATTCCGGAG CCAGAACCGACTACTCATCCTACACAGCCAAAAAAGAAGCAGAAAACGAATATTTTCCAGGGAGACGATGATTTGATCCG GTAA
Upstream 100 bases:
>100_bases TTTAAAAGAATACCAAGGATATAACTTGGACACGGGACTCCGATTTCAAGGAGTAGACAGTATGAAAGAATTTTCACCGT TGGAAGAAGTTTAATCAAAC
Downstream 100 bases:
>100_bases TTGAGAACAAAAATACTTGTCGTTTTGGGATTGAGTACACAAATAGATTTACGGCATGTCCCAAACCAAGGGACAGTTTC GATTGTTAGCAGGAGTTTTA
Product: membrane carboxypeptidase
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 827; Mature: 827
Protein sequence:
>827_residues MKQEPVSYLFRFFVIHFRDKILSRVFNSENPLKQLVKLCSVLLFLNGFLFVFSIKDLWRVPESNQYEKPSVLYGLGEKNE YEPIAEFYRFSRVVLNIKELPPEADGKPNKLIRSFVSTEDNNFYSHWGLDLRGIFRAFMVNILAGRIKEGASTITQQVAR LRFLNTERSFLRKAREAWLALLLEVVFDKDTLMEIYLNEIPLGHGTIGVGAAARFYFRKDVKDLTWGESALLASLTTRPT EFSPLVNPNSSSAKVRVVFKKFVENGILDVKTAEKEYESFSEYYITLNRSPNDSAFGDRLNRFPYFTEYVRKNLTRYIPK STLYSGGLKIYSTLNIQHQTQAEKALYAGLKAQTALSNQRTFTKIDAFDDAYGEIYDLLSMLNDIPDFKFKISRSARTFN RAWQEDLRDELSALNLLSGTESLGETIDWNYKSQQTEDFLLPVEGALISMRPDTGYITAVVGGSGFRSDNQQIRAFQAYR QPGSAFKPIIYAAAMEYFNEHPDPKKNVTAASLFSDSPLQYVLEDGDEWNPSNYTGEYSGFIKLREALELSRNSVAVRVL EHTGISNLMPYLEKILQIENRPIPKNYSISLGTFEVSPYELARAYAVIASGGKQVFPLSVLYVEDGSGKVIKDFREEANK QEKKQILSPAVCFILTSMMEDVIKKGTGTGAASYGLSRPAAGKTGTTNNFRDAWFAGYSSELVSVVWLGYDTGTLSMGKG MSGGVVAAPIWGRFMSNALSREKSKPFHFGETGVVRKQICSISGKLPGSHCHQTEEEYFTKETVPKEVCDDHRGAGFIPE PEPTTHPTQPKKKQKTNIFQGDDDLIR
Sequences:
>Translated_827_residues MKQEPVSYLFRFFVIHFRDKILSRVFNSENPLKQLVKLCSVLLFLNGFLFVFSIKDLWRVPESNQYEKPSVLYGLGEKNE YEPIAEFYRFSRVVLNIKELPPEADGKPNKLIRSFVSTEDNNFYSHWGLDLRGIFRAFMVNILAGRIKEGASTITQQVAR LRFLNTERSFLRKAREAWLALLLEVVFDKDTLMEIYLNEIPLGHGTIGVGAAARFYFRKDVKDLTWGESALLASLTTRPT EFSPLVNPNSSSAKVRVVFKKFVENGILDVKTAEKEYESFSEYYITLNRSPNDSAFGDRLNRFPYFTEYVRKNLTRYIPK STLYSGGLKIYSTLNIQHQTQAEKALYAGLKAQTALSNQRTFTKIDAFDDAYGEIYDLLSMLNDIPDFKFKISRSARTFN RAWQEDLRDELSALNLLSGTESLGETIDWNYKSQQTEDFLLPVEGALISMRPDTGYITAVVGGSGFRSDNQQIRAFQAYR QPGSAFKPIIYAAAMEYFNEHPDPKKNVTAASLFSDSPLQYVLEDGDEWNPSNYTGEYSGFIKLREALELSRNSVAVRVL EHTGISNLMPYLEKILQIENRPIPKNYSISLGTFEVSPYELARAYAVIASGGKQVFPLSVLYVEDGSGKVIKDFREEANK QEKKQILSPAVCFILTSMMEDVIKKGTGTGAASYGLSRPAAGKTGTTNNFRDAWFAGYSSELVSVVWLGYDTGTLSMGKG MSGGVVAAPIWGRFMSNALSREKSKPFHFGETGVVRKQICSISGKLPGSHCHQTEEEYFTKETVPKEVCDDHRGAGFIPE PEPTTHPTQPKKKQKTNIFQGDDDLIR >Mature_827_residues MKQEPVSYLFRFFVIHFRDKILSRVFNSENPLKQLVKLCSVLLFLNGFLFVFSIKDLWRVPESNQYEKPSVLYGLGEKNE YEPIAEFYRFSRVVLNIKELPPEADGKPNKLIRSFVSTEDNNFYSHWGLDLRGIFRAFMVNILAGRIKEGASTITQQVAR LRFLNTERSFLRKAREAWLALLLEVVFDKDTLMEIYLNEIPLGHGTIGVGAAARFYFRKDVKDLTWGESALLASLTTRPT EFSPLVNPNSSSAKVRVVFKKFVENGILDVKTAEKEYESFSEYYITLNRSPNDSAFGDRLNRFPYFTEYVRKNLTRYIPK STLYSGGLKIYSTLNIQHQTQAEKALYAGLKAQTALSNQRTFTKIDAFDDAYGEIYDLLSMLNDIPDFKFKISRSARTFN RAWQEDLRDELSALNLLSGTESLGETIDWNYKSQQTEDFLLPVEGALISMRPDTGYITAVVGGSGFRSDNQQIRAFQAYR QPGSAFKPIIYAAAMEYFNEHPDPKKNVTAASLFSDSPLQYVLEDGDEWNPSNYTGEYSGFIKLREALELSRNSVAVRVL EHTGISNLMPYLEKILQIENRPIPKNYSISLGTFEVSPYELARAYAVIASGGKQVFPLSVLYVEDGSGKVIKDFREEANK QEKKQILSPAVCFILTSMMEDVIKKGTGTGAASYGLSRPAAGKTGTTNNFRDAWFAGYSSELVSVVWLGYDTGTLSMGKG MSGGVVAAPIWGRFMSNALSREKSKPFHFGETGVVRKQICSISGKLPGSHCHQTEEEYFTKETVPKEVCDDHRGAGFIPE PEPTTHPTQPKKKQKTNIFQGDDDLIR
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=828, Percent_Identity=28.2608695652174, Blast_Score=284, Evalue=1e-77, Organism=Escherichia coli, GI1786343, Length=283, Percent_Identity=31.4487632508834, Blast_Score=127, Evalue=3e-30, Organism=Escherichia coli, GI1789601, Length=129, Percent_Identity=41.0852713178295, Blast_Score=90, Evalue=5e-19, Organism=Escherichia coli, GI1788867, Length=169, Percent_Identity=30.1775147928994, Blast_Score=87, Evalue=3e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 93431; Mature: 93431
Theoretical pI: Translated: 8.33; Mature: 8.33
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKQEPVSYLFRFFVIHFRDKILSRVFNSENPLKQLVKLCSVLLFLNGFLFVFSIKDLWRV CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PESNQYEKPSVLYGLGEKNEYEPIAEFYRFSRVVLNIKELPPEADGKPNKLIRSFVSTED CCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC NNFYSHWGLDLRGIFRAFMVNILAGRIKEGASTITQQVARLRFLNTERSFLRKAREAWLA CCEEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH LLLEVVFDKDTLMEIYLNEIPLGHGTIGVGAAARFYFRKDVKDLTWGESALLASLTTRPT HHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC EFSPLVNPNSSSAKVRVVFKKFVENGILDVKTAEKEYESFSEYYITLNRSPNDSAFGDRL CCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHEEEEEEECCCCCCHHHHHH NRFPYFTEYVRKNLTRYIPKSTLYSGGLKIYSTLNIQHQTQAEKALYAGLKAQTALSNQR HCCCHHHHHHHHHHHHHCCCHHHHCCCEEEEEEECCCHHHHHHHHHHHCCHHHHHHCCCC TFTKIDAFDDAYGEIYDLLSMLNDIPDFKFKISRSARTFNRAWQEDLRDELSALNLLSGT CEEEECCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCH ESLGETIDWNYKSQQTEDFLLPVEGALISMRPDTGYITAVVGGSGFRSDNQQIRAFQAYR HHHCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHH QPGSAFKPIIYAAAMEYFNEHPDPKKNVTAASLFSDSPLQYVLEDGDEWNPSNYTGEYSG CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHCCCCCCCCCCCCCCCHHH FIKLREALELSRNSVAVRVLEHTGISNLMPYLEKILQIENRPIPKNYSISLGTFEVSPYE HHHHHHHHHHCCCCCEEEEHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHH LARAYAVIASGGKQVFPLSVLYVEDGSGKVIKDFREEANKQEKKQILSPAVCFILTSMME HHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DVIKKGTGTGAASYGLSRPAAGKTGTTNNFRDAWFAGYSSELVSVVWLGYDTGTLSMGKG HHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHCCCHHHEEEEEEEECCCCCCCCCCC MSGGVVAAPIWGRFMSNALSREKSKPFHFGETGVVRKQICSISGKLPGSHCHQTEEEYFT CCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHH KETVPKEVCDDHRGAGFIPEPEPTTHPTQPKKKQKTNIFQGDDDLIR HHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHCC >Mature Secondary Structure MKQEPVSYLFRFFVIHFRDKILSRVFNSENPLKQLVKLCSVLLFLNGFLFVFSIKDLWRV CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC PESNQYEKPSVLYGLGEKNEYEPIAEFYRFSRVVLNIKELPPEADGKPNKLIRSFVSTED CCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC NNFYSHWGLDLRGIFRAFMVNILAGRIKEGASTITQQVARLRFLNTERSFLRKAREAWLA CCEEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH LLLEVVFDKDTLMEIYLNEIPLGHGTIGVGAAARFYFRKDVKDLTWGESALLASLTTRPT HHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC EFSPLVNPNSSSAKVRVVFKKFVENGILDVKTAEKEYESFSEYYITLNRSPNDSAFGDRL CCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHEEEEEEECCCCCCHHHHHH NRFPYFTEYVRKNLTRYIPKSTLYSGGLKIYSTLNIQHQTQAEKALYAGLKAQTALSNQR HCCCHHHHHHHHHHHHHCCCHHHHCCCEEEEEEECCCHHHHHHHHHHHCCHHHHHHCCCC TFTKIDAFDDAYGEIYDLLSMLNDIPDFKFKISRSARTFNRAWQEDLRDELSALNLLSGT CEEEECCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCH ESLGETIDWNYKSQQTEDFLLPVEGALISMRPDTGYITAVVGGSGFRSDNQQIRAFQAYR HHHCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHH QPGSAFKPIIYAAAMEYFNEHPDPKKNVTAASLFSDSPLQYVLEDGDEWNPSNYTGEYSG CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHCCCCCCCCCCCCCCCHHH FIKLREALELSRNSVAVRVLEHTGISNLMPYLEKILQIENRPIPKNYSISLGTFEVSPYE HHHHHHHHHHCCCCCEEEEHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHH LARAYAVIASGGKQVFPLSVLYVEDGSGKVIKDFREEANKQEKKQILSPAVCFILTSMME HHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DVIKKGTGTGAASYGLSRPAAGKTGTTNNFRDAWFAGYSSELVSVVWLGYDTGTLSMGKG HHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHCCCHHHEEEEEEEECCCCCCCCCCC MSGGVVAAPIWGRFMSNALSREKSKPFHFGETGVVRKQICSISGKLPGSHCHQTEEEYFT CCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHH KETVPKEVCDDHRGAGFIPEPEPTTHPTQPKKKQKTNIFQGDDDLIR HHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA