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The map label for this gene is pcm

Identifier: 45658391

GI number: 45658391

Start: 3088522

End: 3089187

Strand: Direct

Name: pcm

Synonym: LIC12550

Alternate gene names: 45658391

Gene position: 3088522-3089187 (Clockwise)

Preceding gene: 45658390

Following gene: 45658392

Centisome position: 72.21

GC content: 37.99

Gene sequence:

>666_bases
ATGTTTTCTTCGTCTAAAGTCTGTAATCCGATTCTTCGTGAACAAGAAAGAAAAAATATGGTCGATCTTCAAATCGCCTC
TCGAGGAATTAGAGATAAAAAAATTCTCTCTGCAATGCTTTCGATTCCAAGAGAATGTTTTGTTCCGAATTCCCATATTT
TGCAAGCATACGAAGATAAACCACTTCCAATCGGTTGTAATCAAACCATCTCTCAGCCGTTTATGGTAGCATGGATGTCT
TTACTTCTTGAAGTTCGAAAAGGAGACCGTATCTTTGAAATTGGAACCGGCTCGGGTTATCAAAGCGCCGTTTTAATTTT
TTTAGAAGCCACGTTATACTCCGTTGAATTCTTTGACTCTCTTTCTAAAACCGCTACTCAAAATTTAGAATGTTGGAATC
CAGGCTGTACTCAAACGAATCGTTTTATGATCGGAAGTGCGACTGAAATTCTAAAACCGGAACTTCAATTTGATAAGATG
ATTTCTTGCGCTGCACTTCCGAATCTTCCAGATACAAAAAGCTCCTACTTTCAATCTCTTATACCGGGAGGAATTTTTAT
CTTCCCAATGGGAAAACGAGATCAATATTTGATCTTCGCAAAAAGAAATCTCAACGACTGGTCCTTTGAATCCAAAGGTG
GGGTTCGATTTGTTCCTTTACTTTAA

Upstream 100 bases:

>100_bases
TACAAGGCCAAACTCATGGACAGAATAGAAAGACGATCGACACTGTCAACGAAAAAGATCGAAGCCGCTCTTCTCAAATC
CTGTTTAGTGGAGAGACATT

Downstream 100 bases:

>100_bases
CTTGTATCCACGTCTTTATGGATTATTTTAAAAATACTTTTGAATATTCGCTTTTGCAAGATAAAGTATTTTTGAAATTG
TTGATAGAATTCTTTTAATC

Product: protein-L-isoaspartate O-methyltransferase

Products: NA

Alternate protein names: L-isoaspartyl protein carboxyl methyltransferase; Protein L-isoaspartyl methyltransferase; Protein-beta-aspartate methyltransferase; PIMT [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MFSSSKVCNPILREQERKNMVDLQIASRGIRDKKILSAMLSIPRECFVPNSHILQAYEDKPLPIGCNQTISQPFMVAWMS
LLLEVRKGDRIFEIGTGSGYQSAVLIFLEATLYSVEFFDSLSKTATQNLECWNPGCTQTNRFMIGSATEILKPELQFDKM
ISCAALPNLPDTKSSYFQSLIPGGIFIFPMGKRDQYLIFAKRNLNDWSFESKGGVRFVPLL

Sequences:

>Translated_221_residues
MFSSSKVCNPILREQERKNMVDLQIASRGIRDKKILSAMLSIPRECFVPNSHILQAYEDKPLPIGCNQTISQPFMVAWMS
LLLEVRKGDRIFEIGTGSGYQSAVLIFLEATLYSVEFFDSLSKTATQNLECWNPGCTQTNRFMIGSATEILKPELQFDKM
ISCAALPNLPDTKSSYFQSLIPGGIFIFPMGKRDQYLIFAKRNLNDWSFESKGGVRFVPLL
>Mature_221_residues
MFSSSKVCNPILREQERKNMVDLQIASRGIRDKKILSAMLSIPRECFVPNSHILQAYEDKPLPIGCNQTISQPFMVAWMS
LLLEVRKGDRIFEIGTGSGYQSAVLIFLEATLYSVEFFDSLSKTATQNLECWNPGCTQTNRFMIGSATEILKPELQFDKM
ISCAALPNLPDTKSSYFQSLIPGGIFIFPMGKRDQYLIFAKRNLNDWSFESKGGVRFVPLL

Specific function: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins [H]

COG id: COG2518

COG function: function code O; Protein-L-isoaspartate carboxylmethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789100, Length=198, Percent_Identity=36.8686868686869, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: =2.1.1.77 [H]

Molecular weight: Translated: 24982; Mature: 24982

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSSSKVCNPILREQERKNMVDLQIASRGIRDKKILSAMLSIPRECFVPNSHILQAYEDK
CCCCCCCCCHHHHHHHHCCEEEEHHHHCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHCCC
PLPIGCNQTISQPFMVAWMSLLLEVRKGDRIFEIGTGSGYQSAVLIFLEATLYSVEFFDS
CCCCCCCCHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LSKTATQNLECWNPGCTQTNRFMIGSATEILKPELQFDKMISCAALPNLPDTKSSYFQSL
HHHHHHCCCCCCCCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
IPGGIFIFPMGKRDQYLIFAKRNLNDWSFESKGGVRFVPLL
CCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MFSSSKVCNPILREQERKNMVDLQIASRGIRDKKILSAMLSIPRECFVPNSHILQAYEDK
CCCCCCCCCHHHHHHHHCCEEEEHHHHCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHCCC
PLPIGCNQTISQPFMVAWMSLLLEVRKGDRIFEIGTGSGYQSAVLIFLEATLYSVEFFDS
CCCCCCCCHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LSKTATQNLECWNPGCTQTNRFMIGSATEILKPELQFDKMISCAALPNLPDTKSSYFQSL
HHHHHHCCCCCCCCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
IPGGIFIFPMGKRDQYLIFAKRNLNDWSFESKGGVRFVPLL
CCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA