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The map label for this gene is aphA [H]

Identifier: 45658225

GI number: 45658225

Start: 2883898

End: 2885286

Strand: Direct

Name: aphA [H]

Synonym: LIC12379

Alternate gene names: 45658225

Gene position: 2883898-2885286 (Clockwise)

Preceding gene: 45658224

Following gene: 45658226

Centisome position: 67.43

GC content: 32.69

Gene sequence:

>1389_bases
TTGAAAAATAAAATTGAAAAGAATATCGTCTATGGATTAATCATAATTCTTTTTCTAAACCTCATCATGACAGGATCTGC
ATATTATACTCTACAACAATCCTTAGAACTTAGAAAATGGGAAACCCATACTCAAGAAGTTCTTTTAAACCTGGAAGAAA
CCCTTTCTTCATTCAGAGAAACTCATTCCGTCTTAAGGGCTTATATTTTATATCGAGATAAAGAATTAATAGATTCTTAT
TTCAAAAACAAAAGAATAGTTTTAGAAAAAATTCAAGAACTAAGAAATAAAACGGTCGATAACCCGGTAGAACAAAAACG
ACTTTTGAACATAGAATCCAATTTGAAAGAAAAGTTTTCTTATATGGAAGACATACTTTTAATCAAAAAATATAAATCAT
TTCAGGATTATGTTGAATTGTATCGTTCTCCTAATGGATTTACTTTATCGGAAAAAATCAAGTTCCTACTTCAGGAAATC
AAAGACGAAGAACTTAGACTTCTAAACATACGAAAACACAATTCTAAAATCAACATGACCATATCGGTTACTCTTCTTTT
TTCCGGAATTGTATTAAATCTTTCCTTTATTCTTCTACAGAACTGGCTTATCTACAAAGAAAGCCAACGTAGGCTAAAAA
CAGAGGAAATATTAGAAAAATCTAATCAAAATCTCAAACTCTATTCAGAACAATTAGAAAGGTCAAACAGAGATTTAGAA
GCCTTTTCCTATTCGGTTTCTCATGACCTTCGTTCTCCCATTCGAGGTATATTAGGATTTTCTAAAATATTGCTTGAGGA
TCACGGAGCAGAACTCAGAGAAGACAGTCGTAGAATCGTAAACATCATCATTCGAAACTCCGAAAACATGGGGAAACTCA
TAGACGATCTTTTGGAATATTCAAGACTGGGAAGAAGGGAACCAATGTTCTCTGTCGTAAATATGAAAGTTTTGGTAGAG
AAAGTGATTGAAGAAGTTATCAGTTATTATCCGGATATGAAAGCAGAAATTTCCGTCGCAGAACTTCCTTACGCAAATGC
AGACACAAGTCTTCTCAAACAACTTTTATTCAATTTGATTTCCAACGCTTTTAAATATTCTCAAAAAAAAGAAATTCCTA
AAATCGAAATAGGATCGTATCAAAATGGAGAAGAAACCGTTTTCTTTGTAAAAGATAACGGAGCTGGATTTGATATGAAA
TATCAACATAAATTATTCAACATATTTCAAAGGTTACATCATACCGATCAGTTTGAAGGAACCGGGGTCGGACTTGCCAT
CGTCAAAAGGGTAATAGAAAGACACAATGGTAGAGTTTGGGGAAAAGGTAACCTGAACGAGGGCGCTTGTTTTTATTTTA
CGTTAGGAGTCAATGATAAAAATGTATAA

Upstream 100 bases:

>100_bases
GAATAGATGCGAATCGACATGTTTTATAAACTCGTATTATAAGGGTTTAGCTTTCCTTGAATAAAAAGATTTCCAATACT
AGACATTTGAGGTATTTCCT

Downstream 100 bases:

>100_bases
TCTTCAGGATGAATTGATAGAGATCTTATATGCGGAAGACAATCCTCAGGATTCTGAACTTACTCTAAGAAGTTTAAAAA
AACATAAACTTACAGATCAA

Product: histidine kinase sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MKNKIEKNIVYGLIIILFLNLIMTGSAYYTLQQSLELRKWETHTQEVLLNLEETLSSFRETHSVLRAYILYRDKELIDSY
FKNKRIVLEKIQELRNKTVDNPVEQKRLLNIESNLKEKFSYMEDILLIKKYKSFQDYVELYRSPNGFTLSEKIKFLLQEI
KDEELRLLNIRKHNSKINMTISVTLLFSGIVLNLSFILLQNWLIYKESQRRLKTEEILEKSNQNLKLYSEQLERSNRDLE
AFSYSVSHDLRSPIRGILGFSKILLEDHGAELREDSRRIVNIIIRNSENMGKLIDDLLEYSRLGRREPMFSVVNMKVLVE
KVIEEVISYYPDMKAEISVAELPYANADTSLLKQLLFNLISNAFKYSQKKEIPKIEIGSYQNGEETVFFVKDNGAGFDMK
YQHKLFNIFQRLHHTDQFEGTGVGLAIVKRVIERHNGRVWGKGNLNEGACFYFTLGVNDKNV

Sequences:

>Translated_462_residues
MKNKIEKNIVYGLIIILFLNLIMTGSAYYTLQQSLELRKWETHTQEVLLNLEETLSSFRETHSVLRAYILYRDKELIDSY
FKNKRIVLEKIQELRNKTVDNPVEQKRLLNIESNLKEKFSYMEDILLIKKYKSFQDYVELYRSPNGFTLSEKIKFLLQEI
KDEELRLLNIRKHNSKINMTISVTLLFSGIVLNLSFILLQNWLIYKESQRRLKTEEILEKSNQNLKLYSEQLERSNRDLE
AFSYSVSHDLRSPIRGILGFSKILLEDHGAELREDSRRIVNIIIRNSENMGKLIDDLLEYSRLGRREPMFSVVNMKVLVE
KVIEEVISYYPDMKAEISVAELPYANADTSLLKQLLFNLISNAFKYSQKKEIPKIEIGSYQNGEETVFFVKDNGAGFDMK
YQHKLFNIFQRLHHTDQFEGTGVGLAIVKRVIERHNGRVWGKGNLNEGACFYFTLGVNDKNV
>Mature_462_residues
MKNKIEKNIVYGLIIILFLNLIMTGSAYYTLQQSLELRKWETHTQEVLLNLEETLSSFRETHSVLRAYILYRDKELIDSY
FKNKRIVLEKIQELRNKTVDNPVEQKRLLNIESNLKEKFSYMEDILLIKKYKSFQDYVELYRSPNGFTLSEKIKFLLQEI
KDEELRLLNIRKHNSKINMTISVTLLFSGIVLNLSFILLQNWLIYKESQRRLKTEEILEKSNQNLKLYSEQLERSNRDLE
AFSYSVSHDLRSPIRGILGFSKILLEDHGAELREDSRRIVNIIIRNSENMGKLIDDLLEYSRLGRREPMFSVVNMKVLVE
KVIEEVISYYPDMKAEISVAELPYANADTSLLKQLLFNLISNAFKYSQKKEIPKIEIGSYQNGEETVFFVKDNGAGFDMK
YQHKLFNIFQRLHHTDQFEGTGVGLAIVKRVIERHNGRVWGKGNLNEGACFYFTLGVNDKNV

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=353, Percent_Identity=25.4957507082153, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=26.6129032258064, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786912, Length=267, Percent_Identity=26.5917602996255, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789149, Length=256, Percent_Identity=24.21875, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081816, Length=257, Percent_Identity=25.6809338521401, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=28.2157676348548, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=236, Percent_Identity=28.3898305084746, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789808, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=274, Percent_Identity=21.8978102189781, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790551, Length=214, Percent_Identity=27.5700934579439, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788713, Length=225, Percent_Identity=23.1111111111111, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790346, Length=202, Percent_Identity=28.2178217821782, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54229; Mature: 54229

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKIEKNIVYGLIIILFLNLIMTGSAYYTLQQSLELRKWETHTQEVLLNLEETLSSFRE
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THSVLRAYILYRDKELIDSYFKNKRIVLEKIQELRNKTVDNPVEQKRLLNIESNLKEKFS
HHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
YMEDILLIKKYKSFQDYVELYRSPNGFTLSEKIKFLLQEIKDEELRLLNIRKHNSKINMT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEE
ISVTLLFSGIVLNLSFILLQNWLIYKESQRRLKTEEILEKSNQNLKLYSEQLERSNRDLE
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHCCCCHH
AFSYSVSHDLRSPIRGILGFSKILLEDHGAELREDSRRIVNIIIRNSENMGKLIDDLLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHH
SRLGRREPMFSVVNMKVLVEKVIEEVISYYPDMKAEISVAELPYANADTSLLKQLLFNLI
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCCCCCCHHHHHHHHHHHH
SNAFKYSQKKEIPKIEIGSYQNGEETVFFVKDNGAGFDMKYQHKLFNIFQRLHHTDQFEG
HHHHHHHHHCCCCCEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCC
TGVGLAIVKRVIERHNGRVWGKGNLNEGACFYFTLGVNDKNV
CCHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MKNKIEKNIVYGLIIILFLNLIMTGSAYYTLQQSLELRKWETHTQEVLLNLEETLSSFRE
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THSVLRAYILYRDKELIDSYFKNKRIVLEKIQELRNKTVDNPVEQKRLLNIESNLKEKFS
HHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
YMEDILLIKKYKSFQDYVELYRSPNGFTLSEKIKFLLQEIKDEELRLLNIRKHNSKINMT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEE
ISVTLLFSGIVLNLSFILLQNWLIYKESQRRLKTEEILEKSNQNLKLYSEQLERSNRDLE
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHCCCCHH
AFSYSVSHDLRSPIRGILGFSKILLEDHGAELREDSRRIVNIIIRNSENMGKLIDDLLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHH
SRLGRREPMFSVVNMKVLVEKVIEEVISYYPDMKAEISVAELPYANADTSLLKQLLFNLI
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCCCCCCHHHHHHHHHHHH
SNAFKYSQKKEIPKIEIGSYQNGEETVFFVKDNGAGFDMKYQHKLFNIFQRLHHTDQFEG
HHHHHHHHHCCCCCEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCC
TGVGLAIVKRVIERHNGRVWGKGNLNEGACFYFTLGVNDKNV
CCHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]