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The map label for this gene is atoS [H]

Identifier: 45658084

GI number: 45658084

Start: 2700653

End: 2702119

Strand: Reverse

Name: atoS [H]

Synonym: LIC12235

Alternate gene names: 45658084

Gene position: 2702119-2700653 (Counterclockwise)

Preceding gene: 45658088

Following gene: 45658082

Centisome position: 63.18

GC content: 36.33

Gene sequence:

>1467_bases
TTGCCACTAAGAATGAATTTTACCAATCCCTCTATCCTAATTGTAGACGACGAATGGCTGATTGCTTTTAACCTTCAACT
TTCTCTTCAAAAGTTAGGATATAAAATAGCCGGGACGGCAAGAACCGCGGACGAAGCTTTAGAAATGGCCGAACGAACAA
ATCCGGATTTGATTCTAATGGATATTCGTATTGAAGGTGAATTAGATGGAATTCAGGCCGCAGAAAAAATCCAAAAAAAA
ATGGATATTCCAGTTATATTTATGACTGCGTTTGCAGACGAAGAAACCTTTAATCGAGCTGTAGACAAGGCTTCCTTATT
TGGATACATTTCAAAACCTTTTCAGCCTACATCTCTTAAGAATTCTATTGAGATTGCACTCAAACAACAAAAGAGGTTTG
GAAGGGTTAAAGAAGAAGGAAAGGAATTCAAGGATGTAATTCAAAACATTGGTGAGGGTGCGATTTCTCTGGACCGAGAA
GGAAAAATTTTATTTATGAATCGAACTGCGGAGTATCTTACCGGTTGGTCTCTTTCTGAAGTTCAGGGAGAATATGGAGA
AAAGGTTTTAAGATTTTCCACAAACAAAGGAGAAAATATTCGTGCGATGGAGTCCGATCGGTTGAGATACATTCCGTCTT
TATTGACTCGCAATGATGGAAGTAAGATTCAGGTGGCCTTTCGTGTTTCTGCAGTTAGAGACGAGAAAGGATTTATTGTA
GGTTCTATCATTATGCTTTCTGAAATTACGGCTCTTTCTATTTCCGAAAAAGAAAAATCCGAAATGGAAAAAGTCATTCA
ATCCGAAAGAAGATTAGAATCCATTCAGAAACTTGCGGCAGGTCTAGCTCATGAAATCAATAATCCTTTGATGGGAATTA
TCAATTACGGACATGTCATTCAAAATCATAAAGGTGGAGATGCTGAGACTAAAAATTATGCCCGGCTTATCATTGAACAA
GGCGAAAGAATTGCTGCGATCATTCGCAATTTGGTTTTATTTTCCAAAAAAGATCCGGAACAACCTGTAAGGTGTAATGT
AAAACAACTCGTCAATTCTGTGGAAGACATGATTGCTGAAATGTTAAAATTACAAGAAATTCAATTGGAAAAACAAATTC
CGGAAGATTTGGAAATTTCAATTCGTCCGAATCAAATTCGTGAAGTTCTTTATAATATTCTGTATTACTATTCTGAAAAT
CAAAAAAAGGCTTTGATTCATTTGAAAGCCGCTTTGGATTCTGCGGATCCTTCTTATCTTAAAATTTTAATTTCTGGAAA
GCTAAATCTAGATTTGAATCTGAGTGAAGAAAGTAGATTTGAACCATTTGAAAATTTTCGTTCGAATGATTCTCGAATTG
GCATGGGACTTTCGGTTTGTTATGGAATTCTTCAAGCAAACCGAGGACAGCTGCTTCTTAAAAAATCGGAATCTGGTTGG
GATTTTATCGTTCAACTTCCAGTTTAA

Upstream 100 bases:

>100_bases
AAATAAGAACTTAATATCTTTTGAATTCAAGGCCCGTTCGAGTAGAATTCTATAATCTAGATGAAAAAAGGTTTTCAATT
CAAATAGAATCTAATCTTTC

Downstream 100 bases:

>100_bases
ATTTAGACAAAATGGCGCCCTTCTAGGTCTTGAAAAAGATGGGTTAGATATCAAACATTTACCACAAAAGTTGTTTTTAC
TTAGTGAAGTAAATGATTTC

Product: histidine kinase response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MPLRMNFTNPSILIVDDEWLIAFNLQLSLQKLGYKIAGTARTADEALEMAERTNPDLILMDIRIEGELDGIQAAEKIQKK
MDIPVIFMTAFADEETFNRAVDKASLFGYISKPFQPTSLKNSIEIALKQQKRFGRVKEEGKEFKDVIQNIGEGAISLDRE
GKILFMNRTAEYLTGWSLSEVQGEYGEKVLRFSTNKGENIRAMESDRLRYIPSLLTRNDGSKIQVAFRVSAVRDEKGFIV
GSIIMLSEITALSISEKEKSEMEKVIQSERRLESIQKLAAGLAHEINNPLMGIINYGHVIQNHKGGDAETKNYARLIIEQ
GERIAAIIRNLVLFSKKDPEQPVRCNVKQLVNSVEDMIAEMLKLQEIQLEKQIPEDLEISIRPNQIREVLYNILYYYSEN
QKKALIHLKAALDSADPSYLKILISGKLNLDLNLSEESRFEPFENFRSNDSRIGMGLSVCYGILQANRGQLLLKKSESGW
DFIVQLPV

Sequences:

>Translated_488_residues
MPLRMNFTNPSILIVDDEWLIAFNLQLSLQKLGYKIAGTARTADEALEMAERTNPDLILMDIRIEGELDGIQAAEKIQKK
MDIPVIFMTAFADEETFNRAVDKASLFGYISKPFQPTSLKNSIEIALKQQKRFGRVKEEGKEFKDVIQNIGEGAISLDRE
GKILFMNRTAEYLTGWSLSEVQGEYGEKVLRFSTNKGENIRAMESDRLRYIPSLLTRNDGSKIQVAFRVSAVRDEKGFIV
GSIIMLSEITALSISEKEKSEMEKVIQSERRLESIQKLAAGLAHEINNPLMGIINYGHVIQNHKGGDAETKNYARLIIEQ
GERIAAIIRNLVLFSKKDPEQPVRCNVKQLVNSVEDMIAEMLKLQEIQLEKQIPEDLEISIRPNQIREVLYNILYYYSEN
QKKALIHLKAALDSADPSYLKILISGKLNLDLNLSEESRFEPFENFRSNDSRIGMGLSVCYGILQANRGQLLLKKSESGW
DFIVQLPV
>Mature_487_residues
PLRMNFTNPSILIVDDEWLIAFNLQLSLQKLGYKIAGTARTADEALEMAERTNPDLILMDIRIEGELDGIQAAEKIQKKM
DIPVIFMTAFADEETFNRAVDKASLFGYISKPFQPTSLKNSIEIALKQQKRFGRVKEEGKEFKDVIQNIGEGAISLDREG
KILFMNRTAEYLTGWSLSEVQGEYGEKVLRFSTNKGENIRAMESDRLRYIPSLLTRNDGSKIQVAFRVSAVRDEKGFIVG
SIIMLSEITALSISEKEKSEMEKVIQSERRLESIQKLAAGLAHEINNPLMGIINYGHVIQNHKGGDAETKNYARLIIEQG
ERIAAIIRNLVLFSKKDPEQPVRCNVKQLVNSVEDMIAEMLKLQEIQLEKQIPEDLEISIRPNQIREVLYNILYYYSENQ
KKALIHLKAALDSADPSYLKILISGKLNLDLNLSEESRFEPFENFRSNDSRIGMGLSVCYGILQANRGQLLLKKSESGWD
FIVQLPV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=358, Percent_Identity=22.9050279329609, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55383; Mature: 55251

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLRMNFTNPSILIVDDEWLIAFNLQLSLQKLGYKIAGTARTADEALEMAERTNPDLILM
CCEEEECCCCEEEEEECCEEEEEEEEEEHHHCCEEEECCCCHHHHHHHHHHCCCCCEEEE
DIRIEGELDGIQAAEKIQKKMDIPVIFMTAFADEETFNRAVDKASLFGYISKPFQPTSLK
EEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
NSIEIALKQQKRFGRVKEEGKEFKDVIQNIGEGAISLDREGKILFMNRTAEYLTGWSLSE
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCHHHHCCCCHHH
VQGEYGEKVLRFSTNKGENIRAMESDRLRYIPSLLTRNDGSKIQVAFRVSAVRDEKGFIV
HHHHHCCCEEEEECCCCCCEEECCCCHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEEE
GSIIMLSEITALSISEKEKSEMEKVIQSERRLESIQKLAAGLAHEINNPLMGIINYGHVI
EHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
QNHKGGDAETKNYARLIIEQGERIAAIIRNLVLFSKKDPEQPVRCNVKQLVNSVEDMIAE
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
MLKLQEIQLEKQIPEDLEISIRPNQIREVLYNILYYYSENQKKALIHLKAALDSADPSYL
HHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHCCCCCCEE
KILISGKLNLDLNLSEESRFEPFENFRSNDSRIGMGLSVCYGILQANRGQLLLKKSESGW
EEEEECCEEEEEECCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCC
DFIVQLPV
EEEEECCC
>Mature Secondary Structure 
PLRMNFTNPSILIVDDEWLIAFNLQLSLQKLGYKIAGTARTADEALEMAERTNPDLILM
CEEEECCCCEEEEEECCEEEEEEEEEEHHHCCEEEECCCCHHHHHHHHHHCCCCCEEEE
DIRIEGELDGIQAAEKIQKKMDIPVIFMTAFADEETFNRAVDKASLFGYISKPFQPTSLK
EEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
NSIEIALKQQKRFGRVKEEGKEFKDVIQNIGEGAISLDREGKILFMNRTAEYLTGWSLSE
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCHHHHCCCCHHH
VQGEYGEKVLRFSTNKGENIRAMESDRLRYIPSLLTRNDGSKIQVAFRVSAVRDEKGFIV
HHHHHCCCEEEEECCCCCCEEECCCCHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCEEE
GSIIMLSEITALSISEKEKSEMEKVIQSERRLESIQKLAAGLAHEINNPLMGIINYGHVI
EHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
QNHKGGDAETKNYARLIIEQGERIAAIIRNLVLFSKKDPEQPVRCNVKQLVNSVEDMIAE
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
MLKLQEIQLEKQIPEDLEISIRPNQIREVLYNILYYYSENQKKALIHLKAALDSADPSYL
HHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHCCCCCCEE
KILISGKLNLDLNLSEESRFEPFENFRSNDSRIGMGLSVCYGILQANRGQLLLKKSESGW
EEEEECCEEEEEECCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCC
DFIVQLPV
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]