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The map label for this gene is blaR1

Identifier: 45658069

GI number: 45658069

Start: 2678288

End: 2679139

Strand: Direct

Name: blaR1

Synonym: LIC12220

Alternate gene names: 45658069

Gene position: 2678288-2679139 (Clockwise)

Preceding gene: 45658068

Following gene: 45658070

Centisome position: 62.62

GC content: 33.8

Gene sequence:

>852_bases
TTGGTTTTAGATTTAGTGAAAAACGGATTCTTAATCTTTTTAGTTATTCTTTCGTTTCTTTCTTGTAAAATTAATTCTTC
TAATTATATCCTAAGTACAAAATCTTTTTCCGAAAAAAATCTCAACGGAAACCTCTGTGCGATTTTAATCAATCAAACCA
CAAACAATAAAATTTACTTTCAAAAAGATGAATGTTTTTATAAAACTCCCCCTTCTTCTTTGTTTCATCCTGTTTTAGCT
TTCATTTCTGTAGAAGGAGGTTATCTTAAAGAAAATCAAACCCTTTTTTTCTGGGATAAAACTAGATACCCTTATATTCG
TTGGCAAAAAGATCAAAATCTAAAATCTGCTTTGGAATATTCTGTACACTGGTATTTTACAAATTTATGGAATGATATAG
GACCGGAAAAAGGAAAATCACTTTTAGAAAAAATAGGAATCTTTCAGATCCCGAATACAAGAAATTCTTTTTGGTCGGAC
GGCTCTTATACAATTTCACCTTCCGAGTTTGCAGATTTTTTAATGCGACTTCAAGAAATTTCTCCACCTATTCGTAAAAA
GACGATTCAAACCGTTTGGGATTTGTTAAAAAGAACTCCTGGCTCATACTCCAATGCAACCGGAATTCACGATCTTTCGG
GAGACTGGAACGGAGTGGAAGACTATAGATCCGATTCCGCATTTTATTATACACAAGAAGAAACTAGTTCCTGGTTCTGG
GTTTCTTTTCAAAAGTCTAATGTTCGATGGCTCTTACTTACTCGTGTCCGAATTTCGGGAGAAGTTACAAATCCTTTGAA
AGCGGCGGAACTCACTTCTAAAATTCTCAAAGACGAATCCATCATTCCTTAA

Upstream 100 bases:

>100_bases
TAAAATGCAAAAACCTTGGAAGAAAGCGGGAAAAATCTATTTTTTCTTTATTTATATTCCAATCGCGTTTGTTCTAATTT
GTATTTCTATTTTAATGTGA

Downstream 100 bases:

>100_bases
ACGATCCTAAAAAATCTGAATGACGAAACAGGAATTCGTTCCTACAATGCCTCCGAACATGAAAAAAATATCGCTATTTT
ATATTTTTCTAATTTTCTTA

Product: beta-lactamase regulatory protein 1

Products: substituted beta-amino acid

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MVLDLVKNGFLIFLVILSFLSCKINSSNYILSTKSFSEKNLNGNLCAILINQTTNNKIYFQKDECFYKTPPSSLFHPVLA
FISVEGGYLKENQTLFFWDKTRYPYIRWQKDQNLKSALEYSVHWYFTNLWNDIGPEKGKSLLEKIGIFQIPNTRNSFWSD
GSYTISPSEFADFLMRLQEISPPIRKKTIQTVWDLLKRTPGSYSNATGIHDLSGDWNGVEDYRSDSAFYYTQEETSSWFW
VSFQKSNVRWLLLTRVRISGEVTNPLKAAELTSKILKDESIIP

Sequences:

>Translated_283_residues
MVLDLVKNGFLIFLVILSFLSCKINSSNYILSTKSFSEKNLNGNLCAILINQTTNNKIYFQKDECFYKTPPSSLFHPVLA
FISVEGGYLKENQTLFFWDKTRYPYIRWQKDQNLKSALEYSVHWYFTNLWNDIGPEKGKSLLEKIGIFQIPNTRNSFWSD
GSYTISPSEFADFLMRLQEISPPIRKKTIQTVWDLLKRTPGSYSNATGIHDLSGDWNGVEDYRSDSAFYYTQEETSSWFW
VSFQKSNVRWLLLTRVRISGEVTNPLKAAELTSKILKDESIIP
>Mature_283_residues
MVLDLVKNGFLIFLVILSFLSCKINSSNYILSTKSFSEKNLNGNLCAILINQTTNNKIYFQKDECFYKTPPSSLFHPVLA
FISVEGGYLKENQTLFFWDKTRYPYIRWQKDQNLKSALEYSVHWYFTNLWNDIGPEKGKSLLEKIGIFQIPNTRNSFWSD
GSYTISPSEFADFLMRLQEISPPIRKKTIQTVWDLLKRTPGSYSNATGIHDLSGDWNGVEDYRSDSAFYYTQEETSSWFW
VSFQKSNVRWLLLTRVRISGEVTNPLKAAELTSKILKDESIIP

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: 3.5.2.6

Molecular weight: Translated: 32839; Mature: 32839

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLDLVKNGFLIFLVILSFLSCKINSSNYILSTKSFSEKNLNGNLCAILINQTTNNKIYF
CEEHHHHCCHHHHHHHHHHHCEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCCCEEEE
QKDECFYKTPPSSLFHPVLAFISVEGGYLKENQTLFFWDKTRYPYIRWQKDQNLKSALEY
EECCCEEECCCHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCEEEECCCCCHHHHHHH
SVHWYFTNLWNDIGPEKGKSLLEKIGIFQIPNTRNSFWSDGSYTISPSEFADFLMRLQEI
HEEEEEEHHHHHCCHHHHHHHHHHCCEEECCCCCCCCCCCCCEEECHHHHHHHHHHHHHC
SPPIRKKTIQTVWDLLKRTPGSYSNATGIHDLSGDWNGVEDYRSDSAFYYTQEETSSWFW
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCEEE
VSFQKSNVRWLLLTRVRISGEVTNPLKAAELTSKILKDESIIP
EEEECCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVLDLVKNGFLIFLVILSFLSCKINSSNYILSTKSFSEKNLNGNLCAILINQTTNNKIYF
CEEHHHHCCHHHHHHHHHHHCEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCCCEEEE
QKDECFYKTPPSSLFHPVLAFISVEGGYLKENQTLFFWDKTRYPYIRWQKDQNLKSALEY
EECCCEEECCCHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCEEEECCCCCHHHHHHH
SVHWYFTNLWNDIGPEKGKSLLEKIGIFQIPNTRNSFWSDGSYTISPSEFADFLMRLQEI
HEEEEEEHHHHHCCHHHHHHHHHHCCEEECCCCCCCCCCCCCEEECHHHHHHHHHHHHHC
SPPIRKKTIQTVWDLLKRTPGSYSNATGIHDLSGDWNGVEDYRSDSAFYYTQEETSSWFW
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCEEE
VSFQKSNVRWLLLTRVRISGEVTNPLKAAELTSKILKDESIIP
EEEECCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-lactam; H2O

Specific reaction: A beta-lactam + H2O = a substituted beta-amino acid

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]