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The map label for this gene is rfbG

Identifier: 45657999

GI number: 45657999

Start: 2600054

End: 2601145

Strand: Reverse

Name: rfbG

Synonym: LIC12151

Alternate gene names: 45657999

Gene position: 2601145-2600054 (Counterclockwise)

Preceding gene: 45658000

Following gene: 45657998

Centisome position: 60.81

GC content: 37.27

Gene sequence:

>1092_bases
ATGTTTCAAAATATCTATAAAAATAAAAAGGTTCTGGTCACTGGACATACCGGTTTCAAAGGGTCTTGGTTAGTTATTTG
GTTACAGTCTTTAGGTGCGGAAGTAGCAGGATTTTCACTTGGACTTCCAACGTCGCCGAACCATTTTGAATTGCTCAATT
TAGATAAGAAGATTAAAGATTATCGAGGAGACATTCGGGATCGAGCTTCGCTTTCTCAAGCAATAGATGAATTTAAACCT
CAAGTTATTTTTCATATGGCTGCACAAGCATTAGTAAGAAAATCTTACCAAGATCCGGTTGCTACTTTTGAAATCAACAT
TATGGGGATGATCAATTTACTGGATGTTATCCGTACTAAATCGTTTGTAGAAGCCACGATTTTGATTACTAGTGATAAAG
CATACAGAAATGACGAGTGGTGTTGGGGTTATCGTGAGACAGATGTTTTAGGTGGTCACGATCCTTACAGCAGTTCTAAA
AGTTGTGCGGATTTAATTGCACAATCCTATTATTATTCTTTTCTAAAAGATACAAAAACAAAAATTGCAATTACAAGAGC
TGGTAACGTGATCGGTGGCGGAGATTGGGCTGCAGATAGAATTGTTCCGGATTGTATTCGGGCTTGGGGTGGTAACGAAT
CTGTTACGATTCGCAGTCCTTTAGCGACTCGTCCTTGGCAGCATGTATTAGAACCTTTGAGCGGCTATTTATTATTAGGT
GAAAAATTATACATTGGTCAAGAAGGATTGGTCGGAGAGGCATTTAACTTCGGTCCAGATGCAAGTGTTAATCAAACTGT
TTTGGAATTATTAAATGCAATAGCTGAAAGATGGCCTGGGGTTCAATGGGAAATTCCAAAAGGATATGAAGGTGGAGGTA
GGGAAGCCAATCTTCTCAAACTTTCTTGTGACAAAGCTTTATATCATTTAAAATGGAAGCCCGTTTTAGGTTTTTCCGAG
ACGGTTGACTTTACGGTTAATTGGTATAGAAATTGGATTGAAAAAAAAGAAAACGTTTATGATTTCACTCTTTCTCAAAT
TCGTATTTATTGTGAACTAGCTTCAAAAAAGAATTACATTTGGACTCAATAA

Upstream 100 bases:

>100_bases
ATCACGCCGGGTATTGGCAGTGTATGGATACTCTTCGAGATAAACATACTTTGGAAGAACTCTGGAACCAAAATAAAGCG
CCTTGGAAATTTAATTAAGT

Downstream 100 bases:

>100_bases
CAATGAACAAAGTTCTTTTAGAAGGCGTAGTAATTACTTCGTTGAAAGAAATATTCGATCCAAGAGGATCCGTACTACAT
ATGATTCGTATCGATGATCC

Product: CDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MFQNIYKNKKVLVTGHTGFKGSWLVIWLQSLGAEVAGFSLGLPTSPNHFELLNLDKKIKDYRGDIRDRASLSQAIDEFKP
QVIFHMAAQALVRKSYQDPVATFEINIMGMINLLDVIRTKSFVEATILITSDKAYRNDEWCWGYRETDVLGGHDPYSSSK
SCADLIAQSYYYSFLKDTKTKIAITRAGNVIGGGDWAADRIVPDCIRAWGGNESVTIRSPLATRPWQHVLEPLSGYLLLG
EKLYIGQEGLVGEAFNFGPDASVNQTVLELLNAIAERWPGVQWEIPKGYEGGGREANLLKLSCDKALYHLKWKPVLGFSE
TVDFTVNWYRNWIEKKENVYDFTLSQIRIYCELASKKNYIWTQ

Sequences:

>Translated_363_residues
MFQNIYKNKKVLVTGHTGFKGSWLVIWLQSLGAEVAGFSLGLPTSPNHFELLNLDKKIKDYRGDIRDRASLSQAIDEFKP
QVIFHMAAQALVRKSYQDPVATFEINIMGMINLLDVIRTKSFVEATILITSDKAYRNDEWCWGYRETDVLGGHDPYSSSK
SCADLIAQSYYYSFLKDTKTKIAITRAGNVIGGGDWAADRIVPDCIRAWGGNESVTIRSPLATRPWQHVLEPLSGYLLLG
EKLYIGQEGLVGEAFNFGPDASVNQTVLELLNAIAERWPGVQWEIPKGYEGGGREANLLKLSCDKALYHLKWKPVLGFSE
TVDFTVNWYRNWIEKKENVYDFTLSQIRIYCELASKKNYIWTQ
>Mature_363_residues
MFQNIYKNKKVLVTGHTGFKGSWLVIWLQSLGAEVAGFSLGLPTSPNHFELLNLDKKIKDYRGDIRDRASLSQAIDEFKP
QVIFHMAAQALVRKSYQDPVATFEINIMGMINLLDVIRTKSFVEATILITSDKAYRNDEWCWGYRETDVLGGHDPYSSSK
SCADLIAQSYYYSFLKDTKTKIAITRAGNVIGGGDWAADRIVPDCIRAWGGNESVTIRSPLATRPWQHVLEPLSGYLLLG
EKLYIGQEGLVGEAFNFGPDASVNQTVLELLNAIAERWPGVQWEIPKGYEGGGREANLLKLSCDKALYHLKWKPVLGFSE
TVDFTVNWYRNWIEKKENVYDFTLSQIRIYCELASKKNYIWTQ

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7657641, Length=340, Percent_Identity=25, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI48994969, Length=344, Percent_Identity=25.5813953488372, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115532424, Length=345, Percent_Identity=22.3188405797101, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17568069, Length=275, Percent_Identity=24.7272727272727, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013445
- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =4.2.1.45 [H]

Molecular weight: Translated: 41172; Mature: 41172

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQNIYKNKKVLVTGHTGFKGSWLVIWLQSLGAEVAGFSLGLPTSPNHFELLNLDKKIKD
CCCCHHCCCEEEEEECCCCCCCHHEEEEHHHCCHHCCEEECCCCCCCCEEEECCHHHHHH
YRGDIRDRASLSQAIDEFKPQVIFHMAAQALVRKSYQDPVATFEINIMGMINLLDVIRTK
HHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHH
SFVEATILITSDKAYRNDEWCWGYRETDVLGGHDPYSSSKSCADLIAQSYYYSFLKDTKT
HHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE
KIAITRAGNVIGGGDWAADRIVPDCIRAWGGNESVTIRSPLATRPWQHVLEPLSGYLLLG
EEEEEECCCEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCEEEEC
EKLYIGQEGLVGEAFNFGPDASVNQTVLELLNAIAERWPGVQWEIPKGYEGGGREANLLK
CEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEE
LSCDKALYHLKWKPVLGFSETVDFTVNWYRNWIEKKENVYDFTLSQIRIYCELASKKNYI
EECCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHCCCHHHEEHHHEEEEEEECCCCCCC
WTQ
CCC
>Mature Secondary Structure
MFQNIYKNKKVLVTGHTGFKGSWLVIWLQSLGAEVAGFSLGLPTSPNHFELLNLDKKIKD
CCCCHHCCCEEEEEECCCCCCCHHEEEEHHHCCHHCCEEECCCCCCCCEEEECCHHHHHH
YRGDIRDRASLSQAIDEFKPQVIFHMAAQALVRKSYQDPVATFEINIMGMINLLDVIRTK
HHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHH
SFVEATILITSDKAYRNDEWCWGYRETDVLGGHDPYSSSKSCADLIAQSYYYSFLKDTKT
HHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE
KIAITRAGNVIGGGDWAADRIVPDCIRAWGGNESVTIRSPLATRPWQHVLEPLSGYLLLG
EEEEEECCCEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCEEEEC
EKLYIGQEGLVGEAFNFGPDASVNQTVLELLNAIAERWPGVQWEIPKGYEGGGREANLLK
CEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEE
LSCDKALYHLKWKPVLGFSETVDFTVNWYRNWIEKKENVYDFTLSQIRIYCELASKKNYI
EECCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHCCCHHHEEHHHEEEEEEECCCCCCC
WTQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]