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The map label for this gene is galE

Identifier: 45657997

GI number: 45657997

Start: 2598646

End: 2599608

Strand: Reverse

Name: galE

Synonym: LIC12149

Alternate gene names: 45657997

Gene position: 2599608-2598646 (Counterclockwise)

Preceding gene: 45657998

Following gene: 45657996

Centisome position: 60.78

GC content: 37.18

Gene sequence:

>963_bases
TTGGGGCTAGTGATTCTTAAGAGGATATTAATCACTGGCTCTTTCGGGTTTTTAGGTGGAAGAATTGCGCAATATTTCGG
GCAATTAAACGAATACGAATTAATTTTAGGGACTACTAAAAACTTTGAGCTGCCGGATTATATTCGATTTGGAAAAGTAA
TTTTAATTGATTGGAATTCTCAGGCTTCTATGGAGGCAGCCTGTGAAAATGTGGAATACGTCATTCATTGTGCTGGAATG
AACGCGCAAGATGCGACAAAAGATCCACAAAAAGCTTTTGAATTTAACGGGCATGTTACCGGACGTCTGATGGATGCGGC
CATTAAGAATCATTCCTTTAAGTTCATCTATTTTTCAACAGCTCATGTATATGGAAATCCTTTGGTAGGAAATGTTTCCG
AGGCTTCTCCTCTTACAAACGAACATCCTTACGCTCAGAGTAATTTAGCAGGAGAGAGGGAAGTTAGTGATCGCGCAGTT
TTAGGAAAGATTTTCGGCGTTAATCTTCGATTATCAAATGCTTTTGGTGCTCCGGTAAATTCGAAGGTCAATTGCTGGAT
GCTCCTTGTAAACGATCTTTGTAAACAGGCAGTTACAACACGAAAAATGATCCTCAAGACATCTGGAATGCAACGAAGAG
ATTTTATTACTATTCGGGATGTATGTAAAGCGGTTGAACATCTTTTGAGAATAAAATCGAATTATAAAAATGATACATAC
AATGTTGGTGGTTGTATGTCTTTGAGCGTTTGGGAGATGGCAAATTTAGTAAGAGAACGTTGCAAGCAAACTCTTGGATT
TTTACCTGAACTGGAAAGGGTTGAGCCGGATAGAAATGAAATATCGATGGATTTTAATTACAACGTAACAAAACTTCTTT
CGACTGGATTTCATTATTCGAATTCATTTTTGTCTGAAATTGATGATCTATTAACTTTTTGTAATTTGCACTTTAAAGGT
TAG

Upstream 100 bases:

>100_bases
TTTCTAAGGAAAAAGCGCTCATTGCAAATTTTACCGACATACCTCATGATCCATCCGAAGCTGAGCGTTTGCCAGAACAT
GGTTCATTCATTCCATTTAC

Downstream 100 bases:

>100_bases
ATATTTTATGAATCCGCTTGTTTCCGTCGTTATCCCTACTTACAACCACTCAGATTTTTTGAAGCTATCTTTAGCATCGG
TTATAAATCAAACGTATTTG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MGLVILKRILITGSFGFLGGRIAQYFGQLNEYELILGTTKNFELPDYIRFGKVILIDWNSQASMEAACENVEYVIHCAGM
NAQDATKDPQKAFEFNGHVTGRLMDAAIKNHSFKFIYFSTAHVYGNPLVGNVSEASPLTNEHPYAQSNLAGEREVSDRAV
LGKIFGVNLRLSNAFGAPVNSKVNCWMLLVNDLCKQAVTTRKMILKTSGMQRRDFITIRDVCKAVEHLLRIKSNYKNDTY
NVGGCMSLSVWEMANLVRERCKQTLGFLPELERVEPDRNEISMDFNYNVTKLLSTGFHYSNSFLSEIDDLLTFCNLHFKG

Sequences:

>Translated_320_residues
MGLVILKRILITGSFGFLGGRIAQYFGQLNEYELILGTTKNFELPDYIRFGKVILIDWNSQASMEAACENVEYVIHCAGM
NAQDATKDPQKAFEFNGHVTGRLMDAAIKNHSFKFIYFSTAHVYGNPLVGNVSEASPLTNEHPYAQSNLAGEREVSDRAV
LGKIFGVNLRLSNAFGAPVNSKVNCWMLLVNDLCKQAVTTRKMILKTSGMQRRDFITIRDVCKAVEHLLRIKSNYKNDTY
NVGGCMSLSVWEMANLVRERCKQTLGFLPELERVEPDRNEISMDFNYNVTKLLSTGFHYSNSFLSEIDDLLTFCNLHFKG
>Mature_319_residues
GLVILKRILITGSFGFLGGRIAQYFGQLNEYELILGTTKNFELPDYIRFGKVILIDWNSQASMEAACENVEYVIHCAGMN
AQDATKDPQKAFEFNGHVTGRLMDAAIKNHSFKFIYFSTAHVYGNPLVGNVSEASPLTNEHPYAQSNLAGEREVSDRAVL
GKIFGVNLRLSNAFGAPVNSKVNCWMLLVNDLCKQAVTTRKMILKTSGMQRRDFITIRDVCKAVEHLLRIKSNYKNDTYN
VGGCMSLSVWEMANLVRERCKQTLGFLPELERVEPDRNEISMDFNYNVTKLLSTGFHYSNSFLSEIDDLLTFCNLHFKG

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=271, Percent_Identity=28.0442804428044, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36101; Mature: 35970

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLVILKRILITGSFGFLGGRIAQYFGQLNEYELILGTTKNFELPDYIRFGKVILIDWNS
CCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHCCCEEEEECCC
QASMEAACENVEYVIHCAGMNAQDATKDPQKAFEFNGHVTGRLMDAAIKNHSFKFIYFST
CCHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEEE
AHVYGNPLVGNVSEASPLTNEHPYAQSNLAGEREVSDRAVLGKIFGVNLRLSNAFGAPVN
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCCC
SKVNCWMLLVNDLCKQAVTTRKMILKTSGMQRRDFITIRDVCKAVEHLLRIKSNYKNDTY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
NVGGCMSLSVWEMANLVRERCKQTLGFLPELERVEPDRNEISMDFNYNVTKLLSTGFHYS
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEEECCCCHHHHHHHCCCCH
NSFLSEIDDLLTFCNLHFKG
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GLVILKRILITGSFGFLGGRIAQYFGQLNEYELILGTTKNFELPDYIRFGKVILIDWNS
CHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHCCCEEEEECCC
QASMEAACENVEYVIHCAGMNAQDATKDPQKAFEFNGHVTGRLMDAAIKNHSFKFIYFST
CCHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEEE
AHVYGNPLVGNVSEASPLTNEHPYAQSNLAGEREVSDRAVLGKIFGVNLRLSNAFGAPVN
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCCC
SKVNCWMLLVNDLCKQAVTTRKMILKTSGMQRRDFITIRDVCKAVEHLLRIKSNYKNDTY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
NVGGCMSLSVWEMANLVRERCKQTLGFLPELERVEPDRNEISMDFNYNVTKLLSTGFHYS
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEEECCCCHHHHHHHCCCCH
NSFLSEIDDLLTFCNLHFKG
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]