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The map label for this gene is queF [H]

Identifier: 45657695

GI number: 45657695

Start: 2228867

End: 2229268

Strand: Direct

Name: queF [H]

Synonym: LIC11832

Alternate gene names: 45657695

Gene position: 2228867-2229268 (Clockwise)

Preceding gene: 45657693

Following gene: 45657696

Centisome position: 52.11

GC content: 36.82

Gene sequence:

>402_bases
ATGAAAACGAATCATCCAGAAACCTACGACGGAAGACAGGATCATATCCCTTCTTTACAAACTCCCGAGATCGAATCTTT
CACCAATGTTTATGAGGGAAAAGATTACACAATCGATTTTACGGTTCCTGAATTTACTGCAGTTTGTCCCAAAACAGGTC
TTCCCGATTTTGGTGTGATCTTAGTTTCCTACATTCCCAACAAACGTTGTATCGAACTTAAATCCTTTAAAGAATATATC
TTAAGCTATAGAAACGTAGGTATCTTTCATGAATTTTTGGTGAACAAGATCTTGGAAGACGTAATCAAATCGATTGACCC
AAAATACTTGAAAGTGATTGGAGATTATAACGCTCGAGGCGGAATTAAGACGATCGTAACCAGAGAATACAAAAAACCTT
AA

Upstream 100 bases:

>100_bases
GATAACCATTTCAAGCCTCTTCTGGACTTTGCTATCGATTCGGGAAAAAGAATTTTCGCAATTACAAGATCAAAAAATCT
GGTTATCAAGGAAATTGTCC

Downstream 100 bases:

>100_bases
TCGGAATTTAAAACGACATGGACTCTATTACGTTTTTAGGATATATTGCATCCCTACTAACAACAATCTCATTTTTACCC
CAATTGATCCGAATATTGAT

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MKTNHPETYDGRQDHIPSLQTPEIESFTNVYEGKDYTIDFTVPEFTAVCPKTGLPDFGVILVSYIPNKRCIELKSFKEYI
LSYRNVGIFHEFLVNKILEDVIKSIDPKYLKVIGDYNARGGIKTIVTREYKKP

Sequences:

>Translated_133_residues
MKTNHPETYDGRQDHIPSLQTPEIESFTNVYEGKDYTIDFTVPEFTAVCPKTGLPDFGVILVSYIPNKRCIELKSFKEYI
LSYRNVGIFHEFLVNKILEDVIKSIDPKYLKVIGDYNARGGIKTIVTREYKKP
>Mature_133_residues
MKTNHPETYDGRQDHIPSLQTPEIESFTNVYEGKDYTIDFTVPEFTAVCPKTGLPDFGVILVSYIPNKRCIELKSFKEYI
LSYRNVGIFHEFLVNKILEDVIKSIDPKYLKVIGDYNARGGIKTIVTREYKKP

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) [H]

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016856
- InterPro:   IPR020602 [H]

Pfam domain/function: PF01227 GTP_cyclohydroI [H]

EC number: =1.7.1.13 [H]

Molecular weight: Translated: 15353; Mature: 15353

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNHPETYDGRQDHIPSLQTPEIESFTNVYEGKDYTIDFTVPEFTAVCPKTGLPDFGVI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCCHHHHH
LVSYIPNKRCIELKSFKEYILSYRNVGIFHEFLVNKILEDVIKSIDPKYLKVIGDYNARG
HEECCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCC
GIKTIVTREYKKP
CCHHEEECCCCCC
>Mature Secondary Structure
MKTNHPETYDGRQDHIPSLQTPEIESFTNVYEGKDYTIDFTVPEFTAVCPKTGLPDFGVI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCCHHHHH
LVSYIPNKRCIELKSFKEYILSYRNVGIFHEFLVNKILEDVIKSIDPKYLKVIGDYNARG
HEECCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCC
GIKTIVTREYKKP
CCHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA