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The map label for this gene is aspC

Identifier: 45657656

GI number: 45657656

Start: 2181250

End: 2182464

Strand: Reverse

Name: aspC

Synonym: LIC11790

Alternate gene names: 45657656

Gene position: 2182464-2181250 (Counterclockwise)

Preceding gene: 45657657

Following gene: 45657655

Centisome position: 51.03

GC content: 40.66

Gene sequence:

>1215_bases
ATGGATCTCAGCGCAAAGAGGCTGAATGTCATCGAACCTTCTCCTACTCTCGTAATTACTGCTAAGGCAAACGAGTTGAA
AAAAAAGGGAGAAGATATTGTTAGTTTTGGAGCCGGTGAGCCGGATTTTGAAACTCCATCTCATATCAGAGACGCTGCAA
AAAATGCAATCGATAGGGGAATGACTCGTTATACGGCTGTTTCTGGAACGGTTGAATTGAAAGAAGCAATCGTCCACAAG
TTCAAAAGAGACAATGGTCTTGATTACGATAAAAGTCAGGTAATCGTTGGAACCGGTGGTAAACAAGTTATTTACAACTA
CTTTCTCGCAACCTTAAATGCGGGGGACGAAGTAATCATTCCCGCTCCGTATTGGGTGAGTTATGCGGATATTGTTCGTT
TGGCAGAAGGTGTTCCTGTGATTGTCAACACTACTCCGGAGGCAAATTTTCAAATTACTCCGGAACAATTGAAAAAGGTA
ATTACTCCTAAGACAAAATGTTTGATTCTAAATTCTCCCTCCAATCCTACCGGTGCGGGATATACTAAGAAAGATATAGA
AGCTTTGGGAGAGGTTGTACTTTCTACCGGAATTCAAGTCATGAGCGATGACATTTACGAAAAAATAGTCTATGACGGAT
TCGTATTTTCTAATCTTGCTATGTTGTCTCCGGAACTTAAAAAACAAACCTTTGTAATCAATGGAGTTTCTAAAACGTAT
TCCATGACCGGTTGGAGAATTGGCTACGGGGCGGGCGATTTGAATATCGTTAAAAATATGGAAACGATTCAAAGTCAATC
TACTTCGAATCCTTCTTCGATTTCTCAGGCAGCTGCACAAGCTGCAATTGCAGGAGATCAATCCTGTGTAGAGGAGATGA
GAAAAGCGTTTCAAGTCAGAAGAGATCTTATCGTTTCTCTTTTAAATGCGATTCCGGGTGTAAAATGTAACAACCCTCAA
GGAGCCTTTTACGTATTTCCGTATTTGACGGATGTTTACAAAACTACTGGTTTTATAAAACTAAAACAAGGATCTTCCGA
AACCTCTCTCAGTAAAATTTTCTGTAGCACTTTATTAGAAAAATATAAAGTAGCCGCGGTTCCAGGAATTGCATTTGGAG
AAGACCAGGCTCTCAGACTTTCTTACGCAATGGGAGAAAACGACATCCGACGCGGGGTGGAAAGAATCGCGGAAATGATA
AGGGATTTGAACTAG

Upstream 100 bases:

>100_bases
TAGAGAAGCTCAAGAAGAATTGGCTCAGTTACAATTGAATAATGTCTAATTTTTTCCGTGTAATTGAAAAAACGGATCAA
AATAAAAAAAGAGGAATAGC

Downstream 100 bases:

>100_bases
TAAATGATGAGACGGATCGTTCTGATCCTAATCTTTTTTACTTCTTTTCCATGTCTTTGGGGAGGGGATAGATTGGTTCT
AAAACCAAATTCTCCTCTTT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MDLSAKRLNVIEPSPTLVITAKANELKKKGEDIVSFGAGEPDFETPSHIRDAAKNAIDRGMTRYTAVSGTVELKEAIVHK
FKRDNGLDYDKSQVIVGTGGKQVIYNYFLATLNAGDEVIIPAPYWVSYADIVRLAEGVPVIVNTTPEANFQITPEQLKKV
ITPKTKCLILNSPSNPTGAGYTKKDIEALGEVVLSTGIQVMSDDIYEKIVYDGFVFSNLAMLSPELKKQTFVINGVSKTY
SMTGWRIGYGAGDLNIVKNMETIQSQSTSNPSSISQAAAQAAIAGDQSCVEEMRKAFQVRRDLIVSLLNAIPGVKCNNPQ
GAFYVFPYLTDVYKTTGFIKLKQGSSETSLSKIFCSTLLEKYKVAAVPGIAFGEDQALRLSYAMGENDIRRGVERIAEMI
RDLN

Sequences:

>Translated_404_residues
MDLSAKRLNVIEPSPTLVITAKANELKKKGEDIVSFGAGEPDFETPSHIRDAAKNAIDRGMTRYTAVSGTVELKEAIVHK
FKRDNGLDYDKSQVIVGTGGKQVIYNYFLATLNAGDEVIIPAPYWVSYADIVRLAEGVPVIVNTTPEANFQITPEQLKKV
ITPKTKCLILNSPSNPTGAGYTKKDIEALGEVVLSTGIQVMSDDIYEKIVYDGFVFSNLAMLSPELKKQTFVINGVSKTY
SMTGWRIGYGAGDLNIVKNMETIQSQSTSNPSSISQAAAQAAIAGDQSCVEEMRKAFQVRRDLIVSLLNAIPGVKCNNPQ
GAFYVFPYLTDVYKTTGFIKLKQGSSETSLSKIFCSTLLEKYKVAAVPGIAFGEDQALRLSYAMGENDIRRGVERIAEMI
RDLN
>Mature_404_residues
MDLSAKRLNVIEPSPTLVITAKANELKKKGEDIVSFGAGEPDFETPSHIRDAAKNAIDRGMTRYTAVSGTVELKEAIVHK
FKRDNGLDYDKSQVIVGTGGKQVIYNYFLATLNAGDEVIIPAPYWVSYADIVRLAEGVPVIVNTTPEANFQITPEQLKKV
ITPKTKCLILNSPSNPTGAGYTKKDIEALGEVVLSTGIQVMSDDIYEKIVYDGFVFSNLAMLSPELKKQTFVINGVSKTY
SMTGWRIGYGAGDLNIVKNMETIQSQSTSNPSSISQAAAQAAIAGDQSCVEEMRKAFQVRRDLIVSLLNAIPGVKCNNPQ
GAFYVFPYLTDVYKTTGFIKLKQGSSETSLSKIFCSTLLEKYKVAAVPGIAFGEDQALRLSYAMGENDIRRGVERIAEMI
RDLN

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=386, Percent_Identity=27.4611398963731, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI169881279, Length=386, Percent_Identity=27.4611398963731, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI56713254, Length=312, Percent_Identity=26.9230769230769, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI56713256, Length=312, Percent_Identity=26.9230769230769, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI169881281, Length=383, Percent_Identity=24.8041775456919, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI4507369, Length=308, Percent_Identity=26.6233766233766, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI19263340, Length=375, Percent_Identity=23.2, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI215599424, Length=375, Percent_Identity=23.2, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788722, Length=408, Percent_Identity=29.4117647058824, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786816, Length=371, Percent_Identity=24.2587601078167, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788627, Length=323, Percent_Identity=28.4829721362229, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787909, Length=389, Percent_Identity=21.5938303341902, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=350, Percent_Identity=26.2857142857143, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=366, Percent_Identity=25.4098360655738, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=366, Percent_Identity=25.4098360655738, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17567369, Length=260, Percent_Identity=27.3076923076923, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71981209, Length=324, Percent_Identity=23.7654320987654, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=314, Percent_Identity=26.4331210191083, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6323118, Length=347, Percent_Identity=23.0547550432277, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320317, Length=352, Percent_Identity=21.0227272727273, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573069, Length=377, Percent_Identity=24.1379310344828, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24646114, Length=377, Percent_Identity=24.1379310344828, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28573067, Length=377, Percent_Identity=24.1379310344828, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28573065, Length=377, Percent_Identity=24.1379310344828, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI18859735, Length=192, Percent_Identity=26.0416666666667, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44155; Mature: 44155

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSAKRLNVIEPSPTLVITAKANELKKKGEDIVSFGAGEPDFETPSHIRDAAKNAIDRG
CCCCCCCCEEECCCCCEEEEECHHHHHHCCCHHEECCCCCCCCCCHHHHHHHHHHHHHHC
MTRYTAVSGTVELKEAIVHKFKRDNGLDYDKSQVIVGTGGKQVIYNYFLATLNAGDEVII
CHHHEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYADIVRLAEGVPVIVNTTPEANFQITPEQLKKVITPKTKCLILNSPSNPTGAG
CCCHHHHHHHHHHHHCCCCEEEECCCCCCEEECHHHHHHHHCCCCEEEEEECCCCCCCCC
YTKKDIEALGEVVLSTGIQVMSDDIYEKIVYDGFVFSNLAMLSPELKKQTFVINGVSKTY
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHCCEEEEECCCHHE
SMTGWRIGYGAGDLNIVKNMETIQSQSTSNPSSISQAAAQAAIAGDQSCVEEMRKAFQVR
ECCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RDLIVSLLNAIPGVKCNNPQGAFYVFPYLTDVYKTTGFIKLKQGSSETSLSKIFCSTLLE
HHHHHHHHHHCCCCEECCCCCCEEEHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHH
KYKVAAVPGIAFGEDQALRLSYAMGENDIRRGVERIAEMIRDLN
HHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLSAKRLNVIEPSPTLVITAKANELKKKGEDIVSFGAGEPDFETPSHIRDAAKNAIDRG
CCCCCCCCEEECCCCCEEEEECHHHHHHCCCHHEECCCCCCCCCCHHHHHHHHHHHHHHC
MTRYTAVSGTVELKEAIVHKFKRDNGLDYDKSQVIVGTGGKQVIYNYFLATLNAGDEVII
CHHHEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYADIVRLAEGVPVIVNTTPEANFQITPEQLKKVITPKTKCLILNSPSNPTGAG
CCCHHHHHHHHHHHHCCCCEEEECCCCCCEEECHHHHHHHHCCCCEEEEEECCCCCCCCC
YTKKDIEALGEVVLSTGIQVMSDDIYEKIVYDGFVFSNLAMLSPELKKQTFVINGVSKTY
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHCCEEEEECCCHHE
SMTGWRIGYGAGDLNIVKNMETIQSQSTSNPSSISQAAAQAAIAGDQSCVEEMRKAFQVR
ECCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RDLIVSLLNAIPGVKCNNPQGAFYVFPYLTDVYKTTGFIKLKQGSSETSLSKIFCSTLLE
HHHHHHHHHHCCCCEECCCCCCEEEHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHH
KYKVAAVPGIAFGEDQALRLSYAMGENDIRRGVERIAEMIRDLN
HHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA