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The map label for this gene is serB

Identifier: 45657641

GI number: 45657641

Start: 2166673

End: 2167554

Strand: Reverse

Name: serB

Synonym: LIC11775

Alternate gene names: 45657641

Gene position: 2167554-2166673 (Counterclockwise)

Preceding gene: 45657642

Following gene: 45657638

Centisome position: 50.68

GC content: 34.01

Gene sequence:

>882_bases
TTGCTTTTAGTTCTTACAGAAAAGCCAGAAGAAATTCGAAAAGAAATCCTATTAGGAATGGGGGGGGGGATTTCTTTAAA
ACCGGAAGAAACCTTTTTACTTTCTTCTTCTAAGATACGGAATAGAGGTTTTTGGAGTTGTATTGAATGGAAAATTCCAC
GTATCTTAGAACGTTCCGAATTACTTCAATTGAGAGAAACTTTTGCTAAAAAAAATACGGATTTGATTCAAGTGAATCGT
TTGCTGGATCCTAAGGAAAAAAGTTTTTTCTCGTTTGATATGGATTCTACTTTGATTCGTCAAGAGGTTATAGACGAATT
GGCAAGACTCGCTGGAGTTTATGAGGAAGTTGCTTCTGTAACCAAAGAGGCCATGGAAGGAAACCTAGATTTTCATGAGG
CTTTAAAAAAGAGATGTATTTATCTAAAAGGTCTTTCTAGTTCTATTTTTACAGAATTATATCCTAAATTGGAATTGAAT
ACTGGTGTAGAAAGACTTCTGAAAATATTAAAGGAAAATAATACTAGAACCGCAGTTTTTTCCGGAGGTTTTACGGATAT
TTTAGAAATGTTCCAAAAACAGTATGGAATAGATGAAGTTTATGCAAATATTTTAGAAAAAAAAGATGGAGAGCTTTCTG
GAAACGTTCTTGGAGAAATCGTAGACAAAAATAAAAAATTAGAGTATTTAAAAACAATTCGAGACCGGGAAAAAATTCAC
CCTTCTCAAGTAGTGGCGATTGGTGACGGTGCAAATGATTCTTTGATGTTAAACGAAGCCGGAATTGGGATTGGTTTTCA
CGCAAAGGAAGGTTTAAAAAAGCAGATCGTAAACTGGATTGATTTTGCTCCTATGGACGTTCTTTTATTTTTGTTTCCTT
AA

Upstream 100 bases:

>100_bases
TTTTGGCCAGGCCAGGATAAAATTCATGTGAACGAAAAAGCATATCGAGCCTGGATTCATAAATTAAAACCGATACTTTT
ACCCTATCTTTAAGGTTCCC

Downstream 100 bases:

>100_bases
CTTCTTTTGAAAATCTTCCAAAGTTTTTAATGCTTCTATCGGAGTCATTTCTTCTAGTTTGAGTTTTAAAATGGATTCCT
CTGTTTGTGAATTAAAATTT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MLLVLTEKPEEIRKEILLGMGGGISLKPEETFLLSSSKIRNRGFWSCIEWKIPRILERSELLQLRETFAKKNTDLIQVNR
LLDPKEKSFFSFDMDSTLIRQEVIDELARLAGVYEEVASVTKEAMEGNLDFHEALKKRCIYLKGLSSSIFTELYPKLELN
TGVERLLKILKENNTRTAVFSGGFTDILEMFQKQYGIDEVYANILEKKDGELSGNVLGEIVDKNKKLEYLKTIRDREKIH
PSQVVAIGDGANDSLMLNEAGIGIGFHAKEGLKKQIVNWIDFAPMDVLLFLFP

Sequences:

>Translated_293_residues
MLLVLTEKPEEIRKEILLGMGGGISLKPEETFLLSSSKIRNRGFWSCIEWKIPRILERSELLQLRETFAKKNTDLIQVNR
LLDPKEKSFFSFDMDSTLIRQEVIDELARLAGVYEEVASVTKEAMEGNLDFHEALKKRCIYLKGLSSSIFTELYPKLELN
TGVERLLKILKENNTRTAVFSGGFTDILEMFQKQYGIDEVYANILEKKDGELSGNVLGEIVDKNKKLEYLKTIRDREKIH
PSQVVAIGDGANDSLMLNEAGIGIGFHAKEGLKKQIVNWIDFAPMDVLLFLFP
>Mature_293_residues
MLLVLTEKPEEIRKEILLGMGGGISLKPEETFLLSSSKIRNRGFWSCIEWKIPRILERSELLQLRETFAKKNTDLIQVNR
LLDPKEKSFFSFDMDSTLIRQEVIDELARLAGVYEEVASVTKEAMEGNLDFHEALKKRCIYLKGLSSSIFTELYPKLELN
TGVERLLKILKENNTRTAVFSGGFTDILEMFQKQYGIDEVYANILEKKDGELSGNVLGEIVDKNKKLEYLKTIRDREKIH
PSQVVAIGDGANDSLMLNEAGIGIGFHAKEGLKKQIVNWIDFAPMDVLLFLFP

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=186, Percent_Identity=34.4086021505376, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1790849, Length=196, Percent_Identity=40.3061224489796, Blast_Score=141, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI115534454, Length=235, Percent_Identity=32.3404255319149, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534456, Length=258, Percent_Identity=30.6201550387597, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534458, Length=237, Percent_Identity=32.0675105485232, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6321647, Length=210, Percent_Identity=38.5714285714286, Blast_Score=134, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24661601, Length=188, Percent_Identity=34.0425531914894, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 33378; Mature: 33378

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVLTEKPEEIRKEILLGMGGGISLKPEETFLLSSSKIRNRGFWSCIEWKIPRILERSE
CEEEEECCHHHHHHHHHHCCCCCCCCCCCHHEEECCHHHCCCCCCHHHHHCCHHHHHHHH
LLQLRETFAKKNTDLIQVNRLLDPKEKSFFSFDMDSTLIRQEVIDELARLAGVYEEVASV
HHHHHHHHHHCCCCCEEHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
TKEAMEGNLDFHEALKKRCIYLKGLSSSIFTELYPKLELNTGVERLLKILKENNTRTAVF
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEE
SGGFTDILEMFQKQYGIDEVYANILEKKDGELSGNVLGEIVDKNKKLEYLKTIRDREKIH
ECCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCC
PSQVVAIGDGANDSLMLNEAGIGIGFHAKEGLKKQIVNWIDFAPMDVLLFLFP
CCCEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MLLVLTEKPEEIRKEILLGMGGGISLKPEETFLLSSSKIRNRGFWSCIEWKIPRILERSE
CEEEEECCHHHHHHHHHHCCCCCCCCCCCHHEEECCHHHCCCCCCHHHHHCCHHHHHHHH
LLQLRETFAKKNTDLIQVNRLLDPKEKSFFSFDMDSTLIRQEVIDELARLAGVYEEVASV
HHHHHHHHHHCCCCCEEHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
TKEAMEGNLDFHEALKKRCIYLKGLSSSIFTELYPKLELNTGVERLLKILKENNTRTAVF
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEE
SGGFTDILEMFQKQYGIDEVYANILEKKDGELSGNVLGEIVDKNKKLEYLKTIRDREKIH
ECCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCC
PSQVVAIGDGANDSLMLNEAGIGIGFHAKEGLKKQIVNWIDFAPMDVLLFLFP
CCCEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]