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The map label for this gene is fadH

Identifier: 45657595

GI number: 45657595

Start: 2103794

End: 2105803

Strand: Direct

Name: fadH

Synonym: LIC11729

Alternate gene names: 45657595

Gene position: 2103794-2105803 (Clockwise)

Preceding gene: 45657593

Following gene: 45657596

Centisome position: 49.19

GC content: 38.86

Gene sequence:

>2010_bases
ATGAAATATTCCGAAATTTTCCAACCAATTCAAATTGGTTCCATTGTTCTTCCGAACAGAGTCATAATGGGATCAATGCA
TTTAGGATTAGAAGGGATGCCTATGACCGCAGATAGAATGATCGCATTCTACGGTAGACGTTTTGACGGGGGCGCAAGTT
TTATTACTACGGGCGGAATCGCAGTCAACCACGAAGGAAGAGGATCCAATATCTTTTTTAATTTTCAAAGAGAAGAAGAC
TGTAAAGAGTTATCTGTTGTCGCTAATTCTCTCAAGTCCAAAGGTATTTTTTGCGCACAGTTATTTCACGCTGGAAGATA
CGCTTATCATAGAGAGCTCGTAGCACCTTCTGCATTGAGGGCACCTATCAACCGTTATGTTCCAAAGGCTCTTTCCGAAG
AAGAAGCTTGGAAAACCGTAGAAGATTTTGGAGATTCTGCGCTCAAAGCAAAAGAAGTAGGTTTTGGTGCAGTAGAAGTA
ATGGGAAGTGAAGGTTATTTAGTAAATCAATTTTTTTCTCCAGTAACCAACCATAGAGAAGATTTTTTTGGCGGAAGTTC
CGAAAAAAGAATGAACTTTGCAATCGAAGTGATGAAGAACATACGCAAGAAGGTAGGAAAAGATTTTCCAGTAGTTTATC
GTATGTCTGGAATCGATTTGATTCCAGGGAATCCAACTTTTGAAGAAGTGATACTTCTTGCAGAAAAATTAAAAGAAGCG
GGAGCGGATGCTCTTAACATAGGAATTGGTTGGCATGAATCCAGAATTCCTACAATTTCTATGCTCGTTCCTAGAGGTGC
TTGGGCAAAAATTTCCGGAAAAATCAAAGCAAAAGTCAAGGATATTCCAATCATCGCATCGAATAGAGTCAACATGCCAG
AAACCATGTCTAGGATACTCAAAGATCAAGAAGCGGATATTTTGAGTATGGCCAGACCTTTTTTAGCAGATCCTGATATT
CTAAATAAAATCAAAGCTAATCAGGAAGAAAGAATCAATACTTGTATTGCTTGTAACCAAGCTTGTCTGGATCATACGTT
CAAAGAGCAGATGGTTTCTTGTTTAGTTAATCCTTCCGCAAATAGAGAATTAGAACTTAGTAAGTTAAAAAAAGCGGATA
AAAAACACGTGGTTGTAGTAGGTTCTGGACCGGGAGGACTTGAGTCTGCAAGAATCAGTGCAATTCGAGGTCACAAAGTA
ACCGTATTAGAAGCCACAGATAAAATTGGAGGACAACTCAATCTGGCCGCTCAGATTCCAGGAAAATCTGAATTTTTAGA
AACGATACGTTATTTCAAAAATGAACTCAAAAATCTAGGAGTAGAAATTCACTTTGGCTATCAAGCAACGTTAGACAGCA
TTCTCGCGTTAAAACCAGACGCGGTAATTTTTGCGACCGGAGTAAAACCTAGGGAATTTACGTTACCCGGAATAGAAAAA
AAGAAAACAGCTTCTTATGCAGATTATCTTTCCGGAAAATTTCAACCAGGAAACAAAGTGGTGGTTATCGGAGGTGGAGG
AATTGGTTGTGACGTGGCTCATAAACTTACAGAAGAAGATTCTTCTACTATCGATTCCTATTTTCATCGTTACAATGTAA
CGTCTTATACAAACGCACAAATTCAAAAAGAAAAACCGAACCGCAAAGTTTCAATCTTTCGAAGATCCGGAAAAATTGGT
TCCGGATTGGGAGCGACTACCGCTTGGGCTTTACTTCAAGAATTAGAATCAAAGGAAGTAGGATTTTATACTTCTTTAAG
TTATAAAGAAGTTACAGATCAAGGGCTTGTGATAGAAACTAAAAAAGACGGCGCACAAACGATTGAATGCGATTCTATTA
TTCTTTGTGCGGGACAACTGAGCGAAGTTTCTCTTTACGAAGAATTTAAGTCTAAAGTTCCGGAAATTCCATCGTATTTG
ATCGGAGGCGCCAAGGATGCTTCTGGAATTGATGCAAAACGTGCTATGTTAGAAGGATTTGAAGCTGCAATTGAGATCGG
AGTCAATTGA

Upstream 100 bases:

>100_bases
TTCCCACATTTTGAAAGAATATCCATCCCAATAATTCTCTTGCCGGTTTACCAATCTGTTTTCAACATGAGGAAAAGATT
CACTATAAAAAAGGTTTGTT

Downstream 100 bases:

>100_bases
ATGATTTTTGGGTTAAAGTTTACATCAAAAATAAATTAAGTTTAAAAACAGTATTTGTAAAAATGAGTAAACTATTGCAG
ATAAGTAAGTTGAGAATATA

Product: 2,4-dienoyl-coa reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MKYSEIFQPIQIGSIVLPNRVIMGSMHLGLEGMPMTADRMIAFYGRRFDGGASFITTGGIAVNHEGRGSNIFFNFQREED
CKELSVVANSLKSKGIFCAQLFHAGRYAYHRELVAPSALRAPINRYVPKALSEEEAWKTVEDFGDSALKAKEVGFGAVEV
MGSEGYLVNQFFSPVTNHREDFFGGSSEKRMNFAIEVMKNIRKKVGKDFPVVYRMSGIDLIPGNPTFEEVILLAEKLKEA
GADALNIGIGWHESRIPTISMLVPRGAWAKISGKIKAKVKDIPIIASNRVNMPETMSRILKDQEADILSMARPFLADPDI
LNKIKANQEERINTCIACNQACLDHTFKEQMVSCLVNPSANRELELSKLKKADKKHVVVVGSGPGGLESARISAIRGHKV
TVLEATDKIGGQLNLAAQIPGKSEFLETIRYFKNELKNLGVEIHFGYQATLDSILALKPDAVIFATGVKPREFTLPGIEK
KKTASYADYLSGKFQPGNKVVVIGGGGIGCDVAHKLTEEDSSTIDSYFHRYNVTSYTNAQIQKEKPNRKVSIFRRSGKIG
SGLGATTAWALLQELESKEVGFYTSLSYKEVTDQGLVIETKKDGAQTIECDSIILCAGQLSEVSLYEEFKSKVPEIPSYL
IGGAKDASGIDAKRAMLEGFEAAIEIGVN

Sequences:

>Translated_669_residues
MKYSEIFQPIQIGSIVLPNRVIMGSMHLGLEGMPMTADRMIAFYGRRFDGGASFITTGGIAVNHEGRGSNIFFNFQREED
CKELSVVANSLKSKGIFCAQLFHAGRYAYHRELVAPSALRAPINRYVPKALSEEEAWKTVEDFGDSALKAKEVGFGAVEV
MGSEGYLVNQFFSPVTNHREDFFGGSSEKRMNFAIEVMKNIRKKVGKDFPVVYRMSGIDLIPGNPTFEEVILLAEKLKEA
GADALNIGIGWHESRIPTISMLVPRGAWAKISGKIKAKVKDIPIIASNRVNMPETMSRILKDQEADILSMARPFLADPDI
LNKIKANQEERINTCIACNQACLDHTFKEQMVSCLVNPSANRELELSKLKKADKKHVVVVGSGPGGLESARISAIRGHKV
TVLEATDKIGGQLNLAAQIPGKSEFLETIRYFKNELKNLGVEIHFGYQATLDSILALKPDAVIFATGVKPREFTLPGIEK
KKTASYADYLSGKFQPGNKVVVIGGGGIGCDVAHKLTEEDSSTIDSYFHRYNVTSYTNAQIQKEKPNRKVSIFRRSGKIG
SGLGATTAWALLQELESKEVGFYTSLSYKEVTDQGLVIETKKDGAQTIECDSIILCAGQLSEVSLYEEFKSKVPEIPSYL
IGGAKDASGIDAKRAMLEGFEAAIEIGVN
>Mature_669_residues
MKYSEIFQPIQIGSIVLPNRVIMGSMHLGLEGMPMTADRMIAFYGRRFDGGASFITTGGIAVNHEGRGSNIFFNFQREED
CKELSVVANSLKSKGIFCAQLFHAGRYAYHRELVAPSALRAPINRYVPKALSEEEAWKTVEDFGDSALKAKEVGFGAVEV
MGSEGYLVNQFFSPVTNHREDFFGGSSEKRMNFAIEVMKNIRKKVGKDFPVVYRMSGIDLIPGNPTFEEVILLAEKLKEA
GADALNIGIGWHESRIPTISMLVPRGAWAKISGKIKAKVKDIPIIASNRVNMPETMSRILKDQEADILSMARPFLADPDI
LNKIKANQEERINTCIACNQACLDHTFKEQMVSCLVNPSANRELELSKLKKADKKHVVVVGSGPGGLESARISAIRGHKV
TVLEATDKIGGQLNLAAQIPGKSEFLETIRYFKNELKNLGVEIHFGYQATLDSILALKPDAVIFATGVKPREFTLPGIEK
KKTASYADYLSGKFQPGNKVVVIGGGGIGCDVAHKLTEEDSSTIDSYFHRYNVTSYTNAQIQKEKPNRKVSIFRRSGKIG
SGLGATTAWALLQELESKEVGFYTSLSYKEVTDQGLVIETKKDGAQTIECDSIILCAGQLSEVSLYEEFKSKVPEIPSYL
IGGAKDASGIDAKRAMLEGFEAAIEIGVN

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=679, Percent_Identity=41.2371134020619, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI1787939, Length=360, Percent_Identity=25.2777777777778, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=321, Percent_Identity=26.4797507788162, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17564188, Length=318, Percent_Identity=25.4716981132075, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72001454, Length=318, Percent_Identity=25.4716981132075, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17559802, Length=318, Percent_Identity=24.5283018867925, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17565138, Length=318, Percent_Identity=25.1572327044025, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540738, Length=314, Percent_Identity=25.1592356687898, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321973, Length=396, Percent_Identity=23.2323232323232, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325086, Length=396, Percent_Identity=21.4646464646465, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73391; Mature: 73391

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYSEIFQPIQIGSIVLPNRVIMGSMHLGLEGMPMTADRMIAFYGRRFDGGASFITTGGI
CCHHHHCCCHHCCCEECCCEEEEEEHCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEECCE
AVNHEGRGSNIFFNFQREEDCKELSVVANSLKSKGIFCAQLFHAGRYAYHRELVAPSALR
EEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHCCCHHHH
APINRYVPKALSEEEAWKTVEDFGDSALKAKEVGFGAVEVMGSEGYLVNQFFSPVTNHRE
HHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHCCHH
DFFGGSSEKRMNFAIEVMKNIRKKVGKDFPVVYRMSGIDLIPGNPTFEEVILLAEKLKEA
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHHC
GADALNIGIGWHESRIPTISMLVPRGAWAKISGKIKAKVKDIPIIASNRVNMPETMSRIL
CCCEEEEECCCCCCCCCEEEEEECCCCCEEECCEEEEEEECCCEEECCCCCCHHHHHHHH
KDQEADILSMARPFLADPDILNKIKANQEERINTCIACNQACLDHTFKEQMVSCLVNPSA
CCCCCHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
NRELELSKLKKADKKHVVVVGSGPGGLESARISAIRGHKVTVLEATDKIGGQLNLAAQIP
CCEEEHHHHHCCCCCEEEEEECCCCCCCHHHEEEECCCEEEEEECCCCCCCEEEEEEECC
GKSEFLETIRYFKNELKNLGVEIHFGYQATLDSILALKPDAVIFATGVKPREFTLPGIEK
CHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCC
KKTASYADYLSGKFQPGNKVVVIGGGGIGCDVAHKLTEEDSSTIDSYFHRYNVTSYTNAQ
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCE
IQKEKPNRKVSIFRRSGKIGSGLGATTAWALLQELESKEVGFYTSLSYKEVTDQGLVIET
EECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCEEEEE
KKDGAQTIECDSIILCAGQLSEVSLYEEFKSKVPEIPSYLIGGAKDASGIDAKRAMLEGF
CCCCCCEEECCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHH
EAAIEIGVN
HHHEEECCC
>Mature Secondary Structure
MKYSEIFQPIQIGSIVLPNRVIMGSMHLGLEGMPMTADRMIAFYGRRFDGGASFITTGGI
CCHHHHCCCHHCCCEECCCEEEEEEHCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEECCE
AVNHEGRGSNIFFNFQREEDCKELSVVANSLKSKGIFCAQLFHAGRYAYHRELVAPSALR
EEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHCCCHHHH
APINRYVPKALSEEEAWKTVEDFGDSALKAKEVGFGAVEVMGSEGYLVNQFFSPVTNHRE
HHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHCCHH
DFFGGSSEKRMNFAIEVMKNIRKKVGKDFPVVYRMSGIDLIPGNPTFEEVILLAEKLKEA
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHHC
GADALNIGIGWHESRIPTISMLVPRGAWAKISGKIKAKVKDIPIIASNRVNMPETMSRIL
CCCEEEEECCCCCCCCCEEEEEECCCCCEEECCEEEEEEECCCEEECCCCCCHHHHHHHH
KDQEADILSMARPFLADPDILNKIKANQEERINTCIACNQACLDHTFKEQMVSCLVNPSA
CCCCCHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
NRELELSKLKKADKKHVVVVGSGPGGLESARISAIRGHKVTVLEATDKIGGQLNLAAQIP
CCEEEHHHHHCCCCCEEEEEECCCCCCCHHHEEEECCCEEEEEECCCCCCCEEEEEEECC
GKSEFLETIRYFKNELKNLGVEIHFGYQATLDSILALKPDAVIFATGVKPREFTLPGIEK
CHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCC
KKTASYADYLSGKFQPGNKVVVIGGGGIGCDVAHKLTEEDSSTIDSYFHRYNVTSYTNAQ
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCE
IQKEKPNRKVSIFRRSGKIGSGLGATTAWALLQELESKEVGFYTSLSYKEVTDQGLVIET
EECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCEEEEE
KKDGAQTIECDSIILCAGQLSEVSLYEEFKSKVPEIPSYLIGGAKDASGIDAKRAMLEGF
CCCCCCEEECCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHH
EAAIEIGVN
HHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]