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The map label for this gene is glpD

Identifier: 45657565

GI number: 45657565

Start: 2065227

End: 2066879

Strand: Direct

Name: glpD

Synonym: LIC11699

Alternate gene names: 45657565

Gene position: 2065227-2066879 (Clockwise)

Preceding gene: 45657562

Following gene: 45657566

Centisome position: 48.28

GC content: 39.26

Gene sequence:

>1653_bases
ATGCAAATTTGTAGGGGGAAAGAAACCTGTAAAGCAGGAAGAGTTCTCAAAATGGAAAAACAAAAACGAGTCGATCAAAT
TTCTAAACTACAAAAAGAATCCTTTGATATTTTAGTAATCGGAGGTGGGTCTACAGGTGCTGGAGCCGCTTTCGACGCAG
CAAAAAGAGGTTATAAAACAGCTCTGATTGAAAGAAAAGATTTTGCTTCGGGAACTTCTTCCCGTTCCACCAAACTGATT
CATGGTGGGGTCCGTTATTTAGCTCAGTTCCATTTTAAATTGATTCACGAGGCTTTGACGGAAAGGCAGAGGTTATTGGA
AAACGCACCTCACTTAGTCAAACCTCTTAAGTTCGTTTTACCTGCATATCGATTTTACGAAAGACCGTATTACGGAATCG
GTCTTACTCTCTATGATATTCTTGCGTCTAAGGGAAAACTTCCTTCTCACAAAACGGTTTCTAAATCCGAAACAATTTCC
GAGTTTAAAGCCATCAAGAAGGAAGGTTTATTTGGTGGAATTACCTATTACGACGCTCAGTTTAATGATGCTCGTTTGAA
TGTTCTTTTGGCAAGATCTGCACAAAAAGAAGGAGCCGTAGTTGCCAATCGAATAGAACTCGTTTCTTTTATTAAAAAGA
GCGGAAAGATTGTAGGAGCCAATCTCAAAGATTTAGAGACCGCAAAAACCTTTCCAGTTTATACAAAGGTAATCGCAAAT
ACAACTGGAATCTGGGTAGATCACATTCGTAAGTTAGACGATCCAAGAACGTTTAACGTGCTTTCTCCCAGCCAAGGGAT
CCACTTAGTATTCTCCAAAGAAAGAGTTCCTTGTACATCCGCCATGATCATTCCGAAAACAAAGGATGGGCGAGTCGTAT
TTATCATTCCTTGGGAAGACCACGTAATTCTTGGAACCACGGATACTCCGATTGAAAATCCAGGAGAAGAACCACTTCCG
ATCGGAAATGAGGTTCAATTTTTATTGGATACTGGAAACGAATATTTGGAAAATCCAGTCACTGAAAAAGATATTCTTTC
CGTGTTTGTAGGAATTCGTCCTTTGATTTCACCAGAGGGAAATCAGGATACGAAGAATATTTCGAGAGAGGAAGTGATTT
TAGTTTCTAATTCCGGTTTGGTTACGATGGGAGGAGGAAAATGGTCCACTTACAGAAAGATGGCTGAGGATTTGGTGGAT
AAACTCATTCAGATCGGAAATCTAGAAGTTAGAGAAAAATGTTCTACTAAATTTTATGTTTATCCTGGAGCTGCAGATTA
TTCAGAATCTCTTTACCAGGAAATTGAAAAAACATATAAGATCGATACGATCTTTGCAAAAAGGCTTCAAAATTATTATG
GAACGGAAGTTTTCGAAGTTTTGGGAAAAAAACCGAAACTATTGGGAAAAGGAATTCCGTATTTCGAAGAGGAAGTTTTG
TTTGCGGTTAACGAAGAATTTGCGTTAGGCGTCACGGACGTTCTTGCAAGAAGATTTAGAATTCTATTTGTAGATCTCAG
TTTGGCGCAGAAGATGGTCGCTCCTGTGGCTATGGTTCTTTCCAAACAACTCAAGTGGAAGGACAAAACAAAAAAAGCGG
AAGAATCCGCTGCAATGGAGCTAATCGAAAGTTTGAGGAAGTCGTATCGATAA

Upstream 100 bases:

>100_bases
AATTCCTCTTCGCTAATCAGATCAACGGTGCCGCGACGGATAATTTCGATTTGTTTTTGAATGTCCATGAAAGAAAATCC
GAATTGGATTGTGAAACTTA

Downstream 100 bases:

>100_bases
GATTGGATAATTTGGAAAAAAGTTAGAATATTAAAAATATTTAATTCTTAAATTGAAATTTGTTTTATTTGTCGGAGCTA
CGACGATTCCCCATGAAAAA

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MQICRGKETCKAGRVLKMEKQKRVDQISKLQKESFDILVIGGGSTGAGAAFDAAKRGYKTALIERKDFASGTSSRSTKLI
HGGVRYLAQFHFKLIHEALTERQRLLENAPHLVKPLKFVLPAYRFYERPYYGIGLTLYDILASKGKLPSHKTVSKSETIS
EFKAIKKEGLFGGITYYDAQFNDARLNVLLARSAQKEGAVVANRIELVSFIKKSGKIVGANLKDLETAKTFPVYTKVIAN
TTGIWVDHIRKLDDPRTFNVLSPSQGIHLVFSKERVPCTSAMIIPKTKDGRVVFIIPWEDHVILGTTDTPIENPGEEPLP
IGNEVQFLLDTGNEYLENPVTEKDILSVFVGIRPLISPEGNQDTKNISREEVILVSNSGLVTMGGGKWSTYRKMAEDLVD
KLIQIGNLEVREKCSTKFYVYPGAADYSESLYQEIEKTYKIDTIFAKRLQNYYGTEVFEVLGKKPKLLGKGIPYFEEEVL
FAVNEEFALGVTDVLARRFRILFVDLSLAQKMVAPVAMVLSKQLKWKDKTKKAEESAAMELIESLRKSYR

Sequences:

>Translated_550_residues
MQICRGKETCKAGRVLKMEKQKRVDQISKLQKESFDILVIGGGSTGAGAAFDAAKRGYKTALIERKDFASGTSSRSTKLI
HGGVRYLAQFHFKLIHEALTERQRLLENAPHLVKPLKFVLPAYRFYERPYYGIGLTLYDILASKGKLPSHKTVSKSETIS
EFKAIKKEGLFGGITYYDAQFNDARLNVLLARSAQKEGAVVANRIELVSFIKKSGKIVGANLKDLETAKTFPVYTKVIAN
TTGIWVDHIRKLDDPRTFNVLSPSQGIHLVFSKERVPCTSAMIIPKTKDGRVVFIIPWEDHVILGTTDTPIENPGEEPLP
IGNEVQFLLDTGNEYLENPVTEKDILSVFVGIRPLISPEGNQDTKNISREEVILVSNSGLVTMGGGKWSTYRKMAEDLVD
KLIQIGNLEVREKCSTKFYVYPGAADYSESLYQEIEKTYKIDTIFAKRLQNYYGTEVFEVLGKKPKLLGKGIPYFEEEVL
FAVNEEFALGVTDVLARRFRILFVDLSLAQKMVAPVAMVLSKQLKWKDKTKKAEESAAMELIESLRKSYR
>Mature_550_residues
MQICRGKETCKAGRVLKMEKQKRVDQISKLQKESFDILVIGGGSTGAGAAFDAAKRGYKTALIERKDFASGTSSRSTKLI
HGGVRYLAQFHFKLIHEALTERQRLLENAPHLVKPLKFVLPAYRFYERPYYGIGLTLYDILASKGKLPSHKTVSKSETIS
EFKAIKKEGLFGGITYYDAQFNDARLNVLLARSAQKEGAVVANRIELVSFIKKSGKIVGANLKDLETAKTFPVYTKVIAN
TTGIWVDHIRKLDDPRTFNVLSPSQGIHLVFSKERVPCTSAMIIPKTKDGRVVFIIPWEDHVILGTTDTPIENPGEEPLP
IGNEVQFLLDTGNEYLENPVTEKDILSVFVGIRPLISPEGNQDTKNISREEVILVSNSGLVTMGGGKWSTYRKMAEDLVD
KLIQIGNLEVREKCSTKFYVYPGAADYSESLYQEIEKTYKIDTIFAKRLQNYYGTEVFEVLGKKPKLLGKGIPYFEEEVL
FAVNEEFALGVTDVLARRFRILFVDLSLAQKMVAPVAMVLSKQLKWKDKTKKAEESAAMELIESLRKSYR

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=555, Percent_Identity=39.0990990990991, Blast_Score=408, Evalue=1e-114,
Organism=Homo sapiens, GI285002231, Length=555, Percent_Identity=39.0990990990991, Blast_Score=408, Evalue=1e-114,
Organism=Escherichia coli, GI2367226, Length=463, Percent_Identity=30.6695464362851, Blast_Score=175, Evalue=7e-45,
Organism=Escherichia coli, GI1788574, Length=391, Percent_Identity=26.3427109974425, Blast_Score=116, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17509253, Length=563, Percent_Identity=36.9449378330373, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI115534726, Length=513, Percent_Identity=38.401559454191, Blast_Score=347, Evalue=8e-96,
Organism=Saccharomyces cerevisiae, GI6322036, Length=593, Percent_Identity=32.7150084317032, Blast_Score=303, Evalue=4e-83,
Organism=Drosophila melanogaster, GI161077125, Length=546, Percent_Identity=38.2783882783883, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24653942, Length=546, Percent_Identity=38.2783882783883, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24653944, Length=546, Percent_Identity=38.2783882783883, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI20130025, Length=546, Percent_Identity=38.2783882783883, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24586295, Length=542, Percent_Identity=31.549815498155, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI19921278, Length=563, Percent_Identity=31.2611012433393, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI45550977, Length=398, Percent_Identity=28.391959798995, Blast_Score=174, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 61773; Mature: 61773

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQICRGKETCKAGRVLKMEKQKRVDQISKLQKESFDILVIGGGSTGAGAAFDAAKRGYKT
CCCCCCCHHHHCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCHH
ALIERKDFASGTSSRSTKLIHGGVRYLAQFHFKLIHEALTERQRLLENAPHLVKPLKFVL
HHEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
PAYRFYERPYYGIGLTLYDILASKGKLPSHKTVSKSETISEFKAIKKEGLFGGITYYDAQ
HHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECC
FNDARLNVLLARSAQKEGAVVANRIELVSFIKKSGKIVGANLKDLETAKTFPVYTKVIAN
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCHHHHHHHHC
TTGIWVDHIRKLDDPRTFNVLSPSQGIHLVFSKERVPCTSAMIIPKTKDGRVVFIIPWED
CCCHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEEECCC
HVILGTTDTPIENPGEEPLPIGNEVQFLLDTGNEYLENPVTEKDILSVFVGIRPLISPEG
EEEECCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHCHHCCCCCC
NQDTKNISREEVILVSNSGLVTMGGGKWSTYRKMAEDLVDKLIQIGNLEVREKCSTKFYV
CCCHHCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEE
YPGAADYSESLYQEIEKTYKIDTIFAKRLQNYYGTEVFEVLGKKPKLLGKGIPYFEEEVL
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHCCCCCCHHHHHH
FAVNEEFALGVTDVLARRFRILFVDLSLAQKMVAPVAMVLSKQLKWKDKTKKAEESAAME
EEECCCHHCCHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LIESLRKSYR
HHHHHHHHCC
>Mature Secondary Structure
MQICRGKETCKAGRVLKMEKQKRVDQISKLQKESFDILVIGGGSTGAGAAFDAAKRGYKT
CCCCCCCHHHHCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCHH
ALIERKDFASGTSSRSTKLIHGGVRYLAQFHFKLIHEALTERQRLLENAPHLVKPLKFVL
HHEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
PAYRFYERPYYGIGLTLYDILASKGKLPSHKTVSKSETISEFKAIKKEGLFGGITYYDAQ
HHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECC
FNDARLNVLLARSAQKEGAVVANRIELVSFIKKSGKIVGANLKDLETAKTFPVYTKVIAN
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCHHHHHHHHC
TTGIWVDHIRKLDDPRTFNVLSPSQGIHLVFSKERVPCTSAMIIPKTKDGRVVFIIPWED
CCCHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEEECCC
HVILGTTDTPIENPGEEPLPIGNEVQFLLDTGNEYLENPVTEKDILSVFVGIRPLISPEG
EEEECCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHCHHCCCCCC
NQDTKNISREEVILVSNSGLVTMGGGKWSTYRKMAEDLVDKLIQIGNLEVREKCSTKFYV
CCCHHCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEE
YPGAADYSESLYQEIEKTYKIDTIFAKRLQNYYGTEVFEVLGKKPKLLGKGIPYFEEEVL
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHCCCCCCHHHHHH
FAVNEEFALGVTDVLARRFRILFVDLSLAQKMVAPVAMVLSKQLKWKDKTKKAEESAAME
EEECCCHHCCHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LIESLRKSYR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]