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The map label for this gene is yjbC [C]

Identifier: 45657519

GI number: 45657519

Start: 2013175

End: 2013915

Strand: Direct

Name: yjbC [C]

Synonym: LIC11647

Alternate gene names: 45657519

Gene position: 2013175-2013915 (Clockwise)

Preceding gene: 45657516

Following gene: 45657520

Centisome position: 47.07

GC content: 36.57

Gene sequence:

>741_bases
TTGAATCTTTCTGAAATGGAAGAATTCATGCAGCATTTAGAGATTCGATTGAATCGTTTTCTTGCAGATTGTGGTCTTGG
TTCTCGTAGAAAAACGGAGGAACTGATTCAAAAGGGTCATATTGAGATTAATGGTAAACGAGTGACAAACTTGGGGACAA
GGATTGATCCCGAAATAGACGTAGTGTCTTATTTAGGAGATGTAGTAAAACCAATTGTAGAATCTAAAAAGATTCTAATT
TTTAATAAACCCATTGGTTATCTTTGTTCTCATGCAGATCGTTTTCACGAAAAAACGATTTTTTCCCTTTTGCCTTCTGA
TTATAAAAACTTTAAAATTGCAGGACGTCTAGATCTCAATTCAAGGGGACTTTTGATCTTAACCAACGACGGTGCATTGG
CTCAAAAAATTACACATCCTTCTAACGGTTCAGAAAAAGAATATCTCGTGACCTTAAAACACGATCCGGGAGAAAAGTTG
ATTCAAGCCGCTTTTCAAAAAGGGATTTTGGATGCAGGAGAAATTCTACATGCAAAGATGGTTAAACTCGTCCCTGGAAA
AAAATGTGTCTATCGAGTGATTTTAGAAGAAGGAAAAAAAAGACAGATTAGAAGGATGTTTCGGTGGTTTGGGGTGAGTG
TGGTCGATCTTCAAAGAATTAGAATCGGTCCGCTAAAATTAGAAAAATTTAATTTGGAAGAAGGGCAATACCTTCTGGCC
GAAACTGGAATTTGGAAATGA

Upstream 100 bases:

>100_bases
TACAATTCTATACTTTTTACGTGATAAATGGCAAAGTCTTTCCTTCTATCCTTTGAATATTTGTAAAACCGGTCAACGAA
AGTTTTAGGTAGAAGATTTT

Downstream 100 bases:

>100_bases
ATTTTATAAGTATTGAATTTCTTTTATTTTTTTTAGTGTTTTATCTGCTCTATTGGAATATTCCAGCAAAGAGTAGAAAG
TATCTTTTGATAGTAGGGTC

Product: pseudouridylate synthase

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MNLSEMEEFMQHLEIRLNRFLADCGLGSRRKTEELIQKGHIEINGKRVTNLGTRIDPEIDVVSYLGDVVKPIVESKKILI
FNKPIGYLCSHADRFHEKTIFSLLPSDYKNFKIAGRLDLNSRGLLILTNDGALAQKITHPSNGSEKEYLVTLKHDPGEKL
IQAAFQKGILDAGEILHAKMVKLVPGKKCVYRVILEEGKKRQIRRMFRWFGVSVVDLQRIRIGPLKLEKFNLEEGQYLLA
ETGIWK

Sequences:

>Translated_246_residues
MNLSEMEEFMQHLEIRLNRFLADCGLGSRRKTEELIQKGHIEINGKRVTNLGTRIDPEIDVVSYLGDVVKPIVESKKILI
FNKPIGYLCSHADRFHEKTIFSLLPSDYKNFKIAGRLDLNSRGLLILTNDGALAQKITHPSNGSEKEYLVTLKHDPGEKL
IQAAFQKGILDAGEILHAKMVKLVPGKKCVYRVILEEGKKRQIRRMFRWFGVSVVDLQRIRIGPLKLEKFNLEEGQYLLA
ETGIWK
>Mature_246_residues
MNLSEMEEFMQHLEIRLNRFLADCGLGSRRKTEELIQKGHIEINGKRVTNLGTRIDPEIDVVSYLGDVVKPIVESKKILI
FNKPIGYLCSHADRFHEKTIFSLLPSDYKNFKIAGRLDLNSRGLLILTNDGALAQKITHPSNGSEKEYLVTLKHDPGEKL
IQAAFQKGILDAGEILHAKMVKLVPGKKCVYRVILEEGKKRQIRRMFRWFGVSVVDLQRIRIGPLKLEKFNLEEGQYLLA
ETGIWK

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790453, Length=223, Percent_Identity=36.322869955157, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787524, Length=221, Percent_Identity=33.4841628959276, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788510, Length=225, Percent_Identity=32.4444444444444, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87081838, Length=184, Percent_Identity=29.8913043478261, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 28137; Mature: 28137

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSEMEEFMQHLEIRLNRFLADCGLGSRRKTEELIQKGHIEINGKRVTNLGTRIDPEID
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCEEEECCCCCCCCCHH
VVSYLGDVVKPIVESKKILIFNKPIGYLCSHADRFHEKTIFSLLPSDYKNFKIAGRLDLN
HHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECC
SRGLLILTNDGALAQKITHPSNGSEKEYLVTLKHDPGEKLIQAAFQKGILDAGEILHAKM
CCCEEEEECCCHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHH
VKLVPGKKCVYRVILEEGKKRQIRRMFRWFGVSVVDLQRIRIGPLKLEKFNLEEGQYLLA
HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEHHHEEECCEEEEEECCCCCCEEEE
ETGIWK
CCCCCC
>Mature Secondary Structure
MNLSEMEEFMQHLEIRLNRFLADCGLGSRRKTEELIQKGHIEINGKRVTNLGTRIDPEID
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCEEEECCCCCCCCCHH
VVSYLGDVVKPIVESKKILIFNKPIGYLCSHADRFHEKTIFSLLPSDYKNFKIAGRLDLN
HHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECC
SRGLLILTNDGALAQKITHPSNGSEKEYLVTLKHDPGEKLIQAAFQKGILDAGEILHAKM
CCCEEEEECCCHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHH
VKLVPGKKCVYRVILEEGKKRQIRRMFRWFGVSVVDLQRIRIGPLKLEKFNLEEGQYLLA
HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEHHHEEECCEEEEEECCCCCCEEEE
ETGIWK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]