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The map label for this gene is zraR [H]

Identifier: 45657400

GI number: 45657400

Start: 1887446

End: 1888708

Strand: Reverse

Name: zraR [H]

Synonym: LIC11527

Alternate gene names: 45657400

Gene position: 1888708-1887446 (Counterclockwise)

Preceding gene: 45657401

Following gene: 45657399

Centisome position: 44.16

GC content: 31.2

Gene sequence:

>1263_bases
TTGGAAATCGAACTGAAAAAGAAGAATATTCTTCGTAAAATTCCGAATGATCCTATTTTGATCATCGAAGACAAAAAAGA
AAATTGTATTCTTTTAGAAAGTTTATGTGACGAACTTAGTGTTAAACACGAGGTGGCACCTAACGGAGCTGAAGCTTTAA
AACAAATCGAAAATAAGAAATATTCCATTTTTATTTTGGACTTGATGATGCCCGTAATGGACGGAGGTTCCTTTTTAGTT
AAACTTAAAGAAATTTATCCTAACGCGATTGTACTTGTTCAAACGGCCATCGATAGCAATGAGAAAATCATAGAAATTAT
GAAACTAGGAGTTTTCGATTATATTCTAAAACCGATTTATCCAGAAATTTTTCTCAAGATTCTACAAAAGGCACTGAACT
ATTATTTTCTAAAAAATATGGAGGAAAATTTAGCCGAGATAGAAAATCAAAAATTAAGAAATCAACTTGAATGGCTTACT
TATAAAGAGACGATTCGCAAATCGGATAGCGAATCTTTTGAAAAGAATTCGATTCATAGTTTAAAAACTTCCCTTTCCCA
AGGTAGTGGTATCGGTTCCATGATCAGTCTTTTAGATATGATTGATTCCGTTAAAATCCAAGAAGGAAACTTTTATAAAG
TTGATAAGGAAATTTTAGATCTTCTTCTTACGAACAATCGAGTAACTAAGAATATGCTTCTTGGTCTTGAAAAACTATTG
AATCTAATCGATCAAAATTTCGAATTCAATACAACTTCCACTAAAGAAATTCTAGAAAAAACTAAAGACCTTCCCGAAAA
CCTAAATTCATTTCTTTTATCTAAAAAGGTTTCGGTCAAACTTCCAGTTTTTAAAAAAGAACATAAGATAAACGTAAACC
TTTCTCTTTTATATCTTGCAATGGAAGAATTATTTCTAAACGCGTTAAAATATTGTTCTTTCAATTCAACAATCGATGTT
TTTACAAATATCAATCAGAATTATTTTTGTATTACTTTTAAAAATCGAGTAGATGAAAAACCGTATGGAGGGATTCCAGA
AAAGTTTGAACAACTAGTAATCCAACCTTTTTTTAGAATTTATCCTCCCGTTGAAAACGTGAGTCATTTAGAAAAATTCG
GTTTAGGTTTAGGTCTAACTGCGGTAGATCATATCGTCCGTAAACATCACGGTTTATTTTTTATCCATAACGCAAACGAT
CATACTTCCGAAGACGTAAGCCTCTGTGTTCTCGCTGAAATTTTTATACCTTTGGTTTCTTAA

Upstream 100 bases:

>100_bases
GAAGATCTACTTCCTTTCTTCCCAAACTACACGATCCAAAACCCGTTTTCTTTAGATAAATTGAAATCGATTTTAATCGA
AATTGAAAAGGAGATATATC

Downstream 100 bases:

>100_bases
GGAGATAGTTTACATGAAACGAATTCTAATCGTAGATGATTCGGCAGTTTTTAGAAAAATTCTCAGCCTACACCTAAGCA
ATTCCAGTTTCGACATTTTA

Product: histidine kinase response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MEIELKKKNILRKIPNDPILIIEDKKENCILLESLCDELSVKHEVAPNGAEALKQIENKKYSIFILDLMMPVMDGGSFLV
KLKEIYPNAIVLVQTAIDSNEKIIEIMKLGVFDYILKPIYPEIFLKILQKALNYYFLKNMEENLAEIENQKLRNQLEWLT
YKETIRKSDSESFEKNSIHSLKTSLSQGSGIGSMISLLDMIDSVKIQEGNFYKVDKEILDLLLTNNRVTKNMLLGLEKLL
NLIDQNFEFNTTSTKEILEKTKDLPENLNSFLLSKKVSVKLPVFKKEHKINVNLSLLYLAMEELFLNALKYCSFNSTIDV
FTNINQNYFCITFKNRVDEKPYGGIPEKFEQLVIQPFFRIYPPVENVSHLEKFGLGLGLTAVDHIVRKHHGLFFIHNAND
HTSEDVSLCVLAEIFIPLVS

Sequences:

>Translated_420_residues
MEIELKKKNILRKIPNDPILIIEDKKENCILLESLCDELSVKHEVAPNGAEALKQIENKKYSIFILDLMMPVMDGGSFLV
KLKEIYPNAIVLVQTAIDSNEKIIEIMKLGVFDYILKPIYPEIFLKILQKALNYYFLKNMEENLAEIENQKLRNQLEWLT
YKETIRKSDSESFEKNSIHSLKTSLSQGSGIGSMISLLDMIDSVKIQEGNFYKVDKEILDLLLTNNRVTKNMLLGLEKLL
NLIDQNFEFNTTSTKEILEKTKDLPENLNSFLLSKKVSVKLPVFKKEHKINVNLSLLYLAMEELFLNALKYCSFNSTIDV
FTNINQNYFCITFKNRVDEKPYGGIPEKFEQLVIQPFFRIYPPVENVSHLEKFGLGLGLTAVDHIVRKHHGLFFIHNAND
HTSEDVSLCVLAEIFIPLVS
>Mature_420_residues
MEIELKKKNILRKIPNDPILIIEDKKENCILLESLCDELSVKHEVAPNGAEALKQIENKKYSIFILDLMMPVMDGGSFLV
KLKEIYPNAIVLVQTAIDSNEKIIEIMKLGVFDYILKPIYPEIFLKILQKALNYYFLKNMEENLAEIENQKLRNQLEWLT
YKETIRKSDSESFEKNSIHSLKTSLSQGSGIGSMISLLDMIDSVKIQEGNFYKVDKEILDLLLTNNRVTKNMLLGLEKLL
NLIDQNFEFNTTSTKEILEKTKDLPENLNSFLLSKKVSVKLPVFKKEHKINVNLSLLYLAMEELFLNALKYCSFNSTIDV
FTNINQNYFCITFKNRVDEKPYGGIPEKFEQLVIQPFFRIYPPVENVSHLEKFGLGLGLTAVDHIVRKHHGLFFIHNAND
HTSEDVSLCVLAEIFIPLVS

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48374; Mature: 48374

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIELKKKNILRKIPNDPILIIEDKKENCILLESLCDELSVKHEVAPNGAEALKQIENKK
CCEEEHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHCCHHCCCCCHHHHHHHHHCCC
YSIFILDLMMPVMDGGSFLVKLKEIYPNAIVLVQTAIDSNEKIIEIMKLGVFDYILKPIY
EEEEEHHHHHHHHCCCHHEEEEHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCC
PEIFLKILQKALNYYFLKNMEENLAEIENQKLRNQLEWLTYKETIRKSDSESFEKNSIHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LKTSLSQGSGIGSMISLLDMIDSVKIQEGNFYKVDKEILDLLLTNNRVTKNMLLGLEKLL
HHHHHHCCCCHHHHHHHHHHHHCCEECCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHH
NLIDQNFEFNTTSTKEILEKTKDLPENLNSFLLSKKVSVKLPVFKKEHKINVNLSLLYLA
HHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCCCCEEEEEHHHHHHH
MEELFLNALKYCSFNSTIDVFTNINQNYFCITFKNRVDEKPYGGIPEKFEQLVIQPFFRI
HHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
YPPVENVSHLEKFGLGLGLTAVDHIVRKHHGLFFIHNANDHTSEDVSLCVLAEIFIPLVS
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIELKKKNILRKIPNDPILIIEDKKENCILLESLCDELSVKHEVAPNGAEALKQIENKK
CCEEEHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHHCCHHCCCCCHHHHHHHHHCCC
YSIFILDLMMPVMDGGSFLVKLKEIYPNAIVLVQTAIDSNEKIIEIMKLGVFDYILKPIY
EEEEEHHHHHHHHCCCHHEEEEHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCC
PEIFLKILQKALNYYFLKNMEENLAEIENQKLRNQLEWLTYKETIRKSDSESFEKNSIHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LKTSLSQGSGIGSMISLLDMIDSVKIQEGNFYKVDKEILDLLLTNNRVTKNMLLGLEKLL
HHHHHHCCCCHHHHHHHHHHHHCCEECCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHH
NLIDQNFEFNTTSTKEILEKTKDLPENLNSFLLSKKVSVKLPVFKKEHKINVNLSLLYLA
HHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCCCCEEEEEHHHHHHH
MEELFLNALKYCSFNSTIDVFTNINQNYFCITFKNRVDEKPYGGIPEKFEQLVIQPFFRI
HHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
YPPVENVSHLEKFGLGLGLTAVDHIVRKHHGLFFIHNANDHTSEDVSLCVLAEIFIPLVS
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]