Click here to switch to the map view.

The map label for this gene is 45657277

Identifier: 45657277

GI number: 45657277

Start: 1719727

End: 1720725

Strand: Reverse

Name: 45657277

Synonym: LIC11400

Alternate gene names: NA

Gene position: 1720725-1719727 (Counterclockwise)

Preceding gene: 45657278

Following gene: 45657276

Centisome position: 40.23

GC content: 37.34

Gene sequence:

>999_bases
ATGAACTTTTCAAAAGAATTTTCAATCGCATCCAAATTAGATCTAGGCCCTGAACATCCTCCAATCGTCGTAGCCGAAAT
TGGACTCAATCACAACAACGATGAAGAAATCGGCAAAAAAACGATCGCTGCTGCTAAAAAAGCTGGAGCGCAAGCAGTAA
AATTTCAATCCTATGTCACTGAAGAATTTATAGACGTTCACAATCCGGAAGCAAAGGTTTTAGTAGATATATTCAAAAAA
TATGAACTATCGGAAACGATGCATAAAAAATTCCAAAAAACCGCGGAGGAAGAAGGTTTAATTTTTTTCTCCACTCCTCT
TTGTATTAGTTCTCTAAATCTGCTTATAGGTCTAAAAGTTCCATTAATCAAAATTGCAAGTGGAGACGTGACAAACAAAA
CACTTCTTTTAGAAACTGCAAAATCGAAACTACCGGTAATCCTTTCTTCGGGGGCTGCGGATTTTTTTGAACTAAACAGA
GCGATTTCCTTTTTAGAAAAAGAAGGAACAGATAAACTTTGTCTTTTACACTGTGTTTCTATTTATCCTACTCCCCCAGA
AAAAGCGAATCTCAAAGTGTTAGAAACATTCAAAAACCTTTATACGTTTCCGATTGGTTTTTCGGATCATACTACGGGAA
ATATCGCCGCATCCGTAGCCGTTTCCTTAGGGGCTTGTATGATTGAAAAACATTTTACTTTAGATAAAAATCTGGACGGC
CCAGACCATGTTATCTCTGCAAATCCGGAAGAATTGAAAAATGTTTGTGAAAGCGCTTTTACCTCTTGGAAAATGAAAGG
GAACGGTGAAAAAAAACCTTGGCCGGAAGAAATAAACGGAAGATTTTTCGGTAGAAGATCTCTGTATGCAGACTCTAAAG
GAAATCCGATCGCACTTCGTCCGGATCTAACTCAAAAAGATAAAAAATATTTGGATTCTTGGGAAACGGAAAAAACCAAT
CTCTTAAGTCCAAAGCCAGGTAAACCCTTTCATGTTTGA

Upstream 100 bases:

>100_bases
AACCTATCATCTAAAAGCGAAATCATTTTGGAACTTAAGTTATGAGCTAATGAGCCGAAATCTTATATATCCAACTCAAA
AATAAAATACGAAGTAAACC

Downstream 100 bases:

>100_bases
TCGATTGTATTTTTGTAAATTAGAATATTTAATTTTACTAATATTATTTATTATATCTTTCGCTTCTACTTCTGCCGTAA
GTGCGCCAATCGCCTACGGA

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNFSKEFSIASKLDLGPEHPPIVVAEIGLNHNNDEEIGKKTIAAAKKAGAQAVKFQSYVTEEFIDVHNPEAKVLVDIFKK
YELSETMHKKFQKTAEEEGLIFFSTPLCISSLNLLIGLKVPLIKIASGDVTNKTLLLETAKSKLPVILSSGAADFFELNR
AISFLEKEGTDKLCLLHCVSIYPTPPEKANLKVLETFKNLYTFPIGFSDHTTGNIAASVAVSLGACMIEKHFTLDKNLDG
PDHVISANPEELKNVCESAFTSWKMKGNGEKKPWPEEINGRFFGRRSLYADSKGNPIALRPDLTQKDKKYLDSWETEKTN
LLSPKPGKPFHV

Sequences:

>Translated_332_residues
MNFSKEFSIASKLDLGPEHPPIVVAEIGLNHNNDEEIGKKTIAAAKKAGAQAVKFQSYVTEEFIDVHNPEAKVLVDIFKK
YELSETMHKKFQKTAEEEGLIFFSTPLCISSLNLLIGLKVPLIKIASGDVTNKTLLLETAKSKLPVILSSGAADFFELNR
AISFLEKEGTDKLCLLHCVSIYPTPPEKANLKVLETFKNLYTFPIGFSDHTTGNIAASVAVSLGACMIEKHFTLDKNLDG
PDHVISANPEELKNVCESAFTSWKMKGNGEKKPWPEEINGRFFGRRSLYADSKGNPIALRPDLTQKDKKYLDSWETEKTN
LLSPKPGKPFHV
>Mature_332_residues
MNFSKEFSIASKLDLGPEHPPIVVAEIGLNHNNDEEIGKKTIAAAKKAGAQAVKFQSYVTEEFIDVHNPEAKVLVDIFKK
YELSETMHKKFQKTAEEEGLIFFSTPLCISSLNLLIGLKVPLIKIASGDVTNKTLLLETAKSKLPVILSSGAADFFELNR
AISFLEKEGTDKLCLLHCVSIYPTPPEKANLKVLETFKNLYTFPIGFSDHTTGNIAASVAVSLGACMIEKHFTLDKNLDG
PDHVISANPEELKNVCESAFTSWKMKGNGEKKPWPEEINGRFFGRRSLYADSKGNPIALRPDLTQKDKKYLDSWETEKTN
LLSPKPGKPFHV

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=275, Percent_Identity=32.7272727272727, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21357081, Length=280, Percent_Identity=34.6428571428571, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 36824; Mature: 36824

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFSKEFSIASKLDLGPEHPPIVVAEIGLNHNNDEEIGKKTIAAAKKAGAQAVKFQSYVT
CCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
EEFIDVHNPEAKVLVDIFKKYELSETMHKKFQKTAEEEGLIFFSTPLCISSLNLLIGLKV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHEECCC
PLIKIASGDVTNKTLLLETAKSKLPVILSSGAADFFELNRAISFLEKEGTDKLCLLHCVS
CEEEEECCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEHHHH
IYPTPPEKANLKVLETFKNLYTFPIGFSDHTTGNIAASVAVSLGACMIEKHFTLDKNLDG
HCCCCCCCCCHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
PDHVISANPEELKNVCESAFTSWKMKGNGEKKPWPEEINGRFFGRRSLYADSKGNPIALR
CCCEECCCHHHHHHHHHHHHHEEEECCCCCCCCCCHHHCCEEEECCCCCCCCCCCEEEEC
PDLTQKDKKYLDSWETEKTNLLSPKPGKPFHV
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNFSKEFSIASKLDLGPEHPPIVVAEIGLNHNNDEEIGKKTIAAAKKAGAQAVKFQSYVT
CCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
EEFIDVHNPEAKVLVDIFKKYELSETMHKKFQKTAEEEGLIFFSTPLCISSLNLLIGLKV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHEECCC
PLIKIASGDVTNKTLLLETAKSKLPVILSSGAADFFELNRAISFLEKEGTDKLCLLHCVS
CEEEEECCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEHHHH
IYPTPPEKANLKVLETFKNLYTFPIGFSDHTTGNIAASVAVSLGACMIEKHFTLDKNLDG
HCCCCCCCCCHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
PDHVISANPEELKNVCESAFTSWKMKGNGEKKPWPEEINGRFFGRRSLYADSKGNPIALR
CCCEECCCHHHHHHHHHHHHHEEEECCCCCCCCCCHHHCCEEEECCCCCCCCCCCEEEEC
PDLTQKDKKYLDSWETEKTNLLSPKPGKPFHV
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]